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Ontology Browser
Term:
purine-rich negative regulatory element binding (GO:0032422)
Annotations: Rat: (4) Mouse: (4) Human: (4) Chinchilla: (3) Bonobo: (4) Dog: (4) Squirrel: (4) Pig: (4) Naked Mole-rat: (4) Green Monkey: (4)
Parent Terms Term With Siblings Child Terms
cis-regulatory region sequence-specific DNA binding +   
core promoter sequence-specific DNA binding +   
intronic transcription regulatory region sequence-specific DNA binding +   
mitochondrial promoter sequence-specific DNA binding  
plastid promoter transcription regulatory region sequence-specific DNA binding 
purine-rich negative regulatory element binding  
Binding to a 30-bp purine-rich negative regulatory element; the best characterized such element is found in the first intronic region of the rat cardiac alpha-myosin heavy chain gene, and contains two palindromic high-affinity Ets-binding sites (CTTCCCTGGAAG). The presence of this element restricts expression of the gene containing it to cardiac myocytes.
RNA polymerase I transcription regulatory region sequence-specific DNA binding +   
RNA polymerase II transcription regulatory region sequence-specific DNA binding +   
RNA polymerase III transcription regulatory region sequence-specific DNA binding +   
transcription termination site sequence-specific DNA binding  

Synonyms
Broad Synonyms: PNR element binding
Definition Sources: GOC:mah, PMID:9819411

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