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ONTOLOGY REPORT - ANNOTATIONS

Term:chromosome passenger complex
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Accession:GO:0032133 term browser browse the term
Definition:A eukaryotically conserved protein complex that localizes to kinetochores in early mitosis, the spindle mid-zone in anaphase B and to the telophase midbody. It has been proposed that the passenger complex coordinates various events based on its location to different structures during the course of mitosis. Complex members include the BIR-domain-containing protein Survivin, Aurora kinase, INCENP and Borealin.
Synonyms:exact_synonym: CPC complex;   chromosomal passenger complex
 broad_synonym: CPC


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chromosome passenger complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aurka aurora kinase A part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390 		JBrowse link
G Aurkb aurora kinase B part_of IEA
IBA
ISO		 GO_REF:0000107
GO_REF:0000033
(PMID:20562830)
UniProtKB:O15392|UniProtKB:Q53HL2 (PMID:15260989), (PMID:17956729), (PMID:18591255)		 Ensembl
GO_Central
RGD		 PMID:15260989 PMID:17956729 PMID:18591255 PMID:20562830 GO_REF:0000033 GO_REF:0000107 NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837 		JBrowse link
G Aurkc aurora kinase C part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:66,843,653...66,849,775
Ensembl chr 1:66,843,653...66,864,386 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 part_of ISS
ISO
IBA		 GO_REF:0000024
UniProtKB:Q53HL2|UniProtKB:Q96GD4 (PMID:15260989), (PMID:17956729), (PMID:18591255)
GO_REF:0000033		 UniProt
RGD
GO_Central		 PMID:15260989 PMID:17956729 PMID:18591255 GO_REF:0000024 GO_REF:0000033 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380 		JBrowse link
G Cdca8 cell division cycle associated 8 part_of ISS
IBA
ISO		 GO_REF:0000024
GO_REF:0000033
UniProtKB:O15392|UniProtKB:Q96GD4 (PMID:15260989), (PMID:17956729), (PMID:18591255)		 UniProt
GO_Central
RGD		 PMID:15260989 PMID:17956729 PMID:18591255 GO_REF:0000024 GO_REF:0000033 NCBI chr 5:137,176,414...137,198,686
Ensembl chr 5:137,176,417...137,198,629 		JBrowse link
G Incenp inner centromere protein part_of IBA
ISO		 GO_REF:0000033
(PMID:17956729)		 GO_Central
RGD		 PMID:17956729 GO_REF:0000033 NCBI chr 1:206,520,655...206,550,575
Ensembl chr 1:206,523,380...206,553,265 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20833
    protein-containing complex 6558
      microtubule associated complex 150
        chromosome passenger complex 6
Path 2
Term Annotations click to browse term
  cellular_component 20833
    cellular anatomical structure 20633
      organelle 13975
        membraneless organelle 5268
          intracellular membraneless organelle 5268
            cytoskeleton 2384
              microtubule cytoskeleton 1407
                microtubule associated complex 150
                  chromosome passenger complex 6
paths to the root