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ONTOLOGY REPORT - ANNOTATIONS

Term:Cul4A-RING E3 ubiquitin ligase complex
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Accession:GO:0031464 term browser browse the term
Definition:A ubiquitin ligase complex in which a cullin from the Cul4A subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by an adaptor protein.
Synonyms:exact_synonym: CDL4 complex;   CRL4 complex;   DCX complex;   cullin-RING ligase 4A
 narrow_synonym: VDC complex
 related_synonym: SCF4 complex

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Cul4A-RING E3 ubiquitin ligase complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arih1 ariadne RBR E3 ubiquitin protein ligase 1 located_in ISO (PMID:24076655) UniProt PMID:24076655 NCBI chrNW_004624781:1,567,343...1,665,766 JBrowse link
G Cdkn1b cyclin dependent kinase inhibitor 1B part_of IEA Ensembl GO_REF:0000107 NCBI chrNW_004624752:25,202,474...25,207,107
Ensembl chrNW_004624752:25,203,474...25,207,114 		JBrowse link
G Cop1 COP1 E3 ubiquitin ligase part_of ISO (PMID:14739464) UniProt PMID:14739464 NCBI chrNW_004624771:5,922,086...6,132,537
Ensembl chrNW_004624771:5,922,067...6,133,597 		JBrowse link
G Crbn cereblon part_of IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624773:13,383,697...13,406,892
Ensembl chrNW_004624773:13,384,383...13,407,191 		JBrowse link
G Cul4a cullin 4A part_of ISO (PMID:22118460)
(PMID:12732143), (PMID:14739464), (PMID:17085480), (PMID:18794347), (PMID:20129063), (PMID:20223979)		 ComplexPortal
UniProt		 PMID:12732143 PMID:14739464 PMID:17085480 PMID:18794347 PMID:20129063 More... NCBI chrNW_004624793:686,720...722,516
Ensembl chrNW_004624793:688,135...722,490 		JBrowse link
G Cul4b cullin 4B part_of ISO (PMID:22118460) ComplexPortal PMID:22118460 NCBI chrNW_004624931:431,835...568,609 JBrowse link
G Ddb1 damage specific DNA binding protein 1 part_of ISO (PMID:22118460)
(PMID:12732143), (PMID:14739464), (PMID:18794347), (PMID:20129063), (PMID:20223979)		 ComplexPortal
UniProt		 PMID:12732143 PMID:14739464 PMID:18794347 PMID:20129063 PMID:20223979 More... NCBI chrNW_004624926:871,003...893,902
Ensembl chrNW_004624926:871,000...897,777 		JBrowse link
G Ddb2 damage specific DNA binding protein 2 part_of ISO (PMID:22118460) ComplexPortal PMID:22118460 NCBI chrNW_004624767:1,481,151...1,495,073
Ensembl chrNW_004624767:1,481,447...1,492,467 		JBrowse link
G Det1 DET1 partner of COP1 E3 ubiquitin ligase part_of ISO (PMID:14739464) UniProt PMID:14739464 NCBI chrNW_004624768:15,869,949...15,919,368
Ensembl chrNW_004624768:15,870,035...15,884,201 		JBrowse link
G Dtl denticleless E3 ubiquitin protein ligase homolog part_of IEA Ensembl GO_REF:0000107 NCBI chrNW_004624771:17,612,264...17,660,772
Ensembl chrNW_004624771:17,612,284...17,662,405 		JBrowse link
G Ercc8 ERCC excision repair 8, CSA ubiquitin ligase complex subunit part_of IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624815:9,054,576...9,135,136
Ensembl chrNW_004624815:9,054,651...9,134,286 		JBrowse link
G Glmn glomulin, FKBP associated protein part_of ISO (PMID:22405651) MGI PMID:22405651 NCBI chrNW_004624742:5,434,588...5,477,647 JBrowse link
G Rbx1 ring-box 1 part_of IEA Ensembl GO_REF:0000107 NCBI chrNW_004624752:7,547,702...7,560,605
Ensembl chrNW_004624752:7,546,959...7,560,668 		JBrowse link
G Trpc4ap transient receptor potential cation channel subfamily C member 4 associated protein part_of IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004624842:4,317,710...4,395,792
Ensembl chrNW_004624842:4,316,578...4,395,792 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 18619
    protein-containing complex 6050
      intracellular protein-containing complex 882
        ubiquitin ligase complex 298
          cullin-RING ubiquitin ligase complex 184
            Cul4-RING E3 ubiquitin ligase complex 36
              Cul4A-RING E3 ubiquitin ligase complex 14
Path 2
Term Annotations click to browse term
  cellular_component 18619
    protein-containing complex 6050
      catalytic complex 1701
        transferase complex 835
          ubiquitin ligase complex 298
            cullin-RING ubiquitin ligase complex 184
              Cul4-RING E3 ubiquitin ligase complex 36
                Cul4A-RING E3 ubiquitin ligase complex 14
paths to the root