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ONTOLOGY REPORT - ANNOTATIONS

Term:Cul4A-RING E3 ubiquitin ligase complex
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Accession:GO:0031464 term browser browse the term
Definition:A ubiquitin ligase complex in which a cullin from the Cul4A subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by an adaptor protein.
Synonyms:exact_synonym: CDL4 complex;   CRL4 complex;   DCX complex;   cullin-RING ligase 4A
 narrow_synonym: VDC complex
 related_synonym: SCF4 complex

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Cul4A-RING E3 ubiquitin ligase complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 part_of
located_in		 IEA
ISO		 (PMID:24076655) Ensembl
UniProt		 PMID:24076655 GO_REF:0000107 NCBI chr26:10,890,440...11,002,812
Ensembl chr26:10,893,735...11,002,159 		JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B part_of IEA Ensembl GO_REF:0000107 NCBI chr11:12,612,064...12,617,228
Ensembl chr11:12,612,079...12,617,531 		JBrowse link
G COP1 COP1 E3 ubiquitin ligase part_of IEA Ensembl GO_REF:0000107 NCBI chr25:53,057,479...53,316,662
Ensembl chr25:53,057,784...53,314,398 		JBrowse link
G CRBN cereblon part_of IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr22:39,248,087...39,277,778
Ensembl chr22:39,248,905...39,277,749 		JBrowse link
G CUL4A cullin 4A part_of IEA Ensembl GO_REF:0000107 NCBI chr 3:91,211,238...91,267,236
Ensembl chr 3:91,212,193...91,268,838 		JBrowse link
G CUL4B cullin 4B part_of ISO (PMID:22118460) ComplexPortal PMID:22118460
G DDB1 damage specific DNA binding protein 1 part_of IEA Ensembl GO_REF:0000107 NCBI chr 1:12,508,712...12,543,127
Ensembl chr 1:12,508,443...12,544,913 		JBrowse link
G DDB2 damage specific DNA binding protein 2 part_of ISO (PMID:22118460) ComplexPortal PMID:22118460 NCBI chr 1:18,071,011...18,096,660
Ensembl chr 1:18,071,383...18,096,595 		JBrowse link
G DET1 DET1 partner of COP1 E3 ubiquitin ligase part_of IEA Ensembl GO_REF:0000107 NCBI chr29:7,078,777...7,103,174
Ensembl chr29:7,078,578...7,096,486 		JBrowse link
G DTL denticleless E3 ubiquitin protein ligase homolog part_of IEA Ensembl GO_REF:0000107 NCBI chr25:17,418,078...17,485,320
Ensembl chr25:17,418,090...17,485,164 		JBrowse link
G ERCC8 ERCC excision repair 8, CSA ubiquitin ligase complex subunit part_of IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 4:57,048,262...57,128,338
Ensembl chr 4:57,045,018...57,128,307 		JBrowse link
G GLMN glomulin, FKBP associated protein part_of IEA Ensembl GO_REF:0000107 NCBI chr20:40,950,948...41,007,120
Ensembl chr20:40,951,342...41,008,791 		JBrowse link
G RBX1 ring-box 1 part_of IEA Ensembl GO_REF:0000107 NCBI chr19:23,500,361...23,521,676
Ensembl chr19:23,500,356...23,522,723 		JBrowse link
G TRPC4AP transient receptor potential cation channel subfamily C member 4 associated protein part_of IEA Ensembl
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 2:39,304,240...39,391,447
Ensembl chr 2:39,305,203...39,391,418 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 17898
    protein-containing complex 5833
      intracellular protein-containing complex 892
        ubiquitin ligase complex 307
          cullin-RING ubiquitin ligase complex 192
            Cul4-RING E3 ubiquitin ligase complex 38
              Cul4A-RING E3 ubiquitin ligase complex 14
Path 2
Term Annotations click to browse term
  cellular_component 17898
    protein-containing complex 5833
      catalytic complex 1754
        transferase complex 851
          ubiquitin ligase complex 307
            cullin-RING ubiquitin ligase complex 192
              Cul4-RING E3 ubiquitin ligase complex 38
                Cul4A-RING E3 ubiquitin ligase complex 14
paths to the root