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ONTOLOGY REPORT - ANNOTATIONS

Term:nucleoside diphosphate phosphatase activity
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Accession:GO:0017110 term browser browse the term
Definition:Catalysis of the reaction: a nucleoside diphosphate + H2O = a nucleoside monophosphate + phosphate.
Synonyms:exact_synonym: nucleoside diphosphatase activity
 narrow_synonym: inosine 5'-diphosphatase;   inosine diphosphatase;   type B nucleoside diphosphatase;   type L nucleoside diphosphatase
 broad_synonym: apyrase activity
 related_synonym: NDPase activity;   nucleoside 5'-diphosphatase activity;   nucleoside diphosphate phosphohydrolase activity
 xref: EC:3.6.1.6;   MetaCyc:NUCLEOSIDE-DIPHOSPHATASE-RXN;   RHEA:36799;   reactome:R-HSA-8850854 "NTPDase1 hydrolyzes nucleoside diphosphates";   reactome:R-HSA-8851129 "NTPDase3 hydrolyzes nucleoside diphosphates";   reactome:R-HSA-8851225 "NTPDase4 hydrolyzes nucleoside diphosphates";   reactome:R-HSA-8851356 "NTPDase5 hydrolyzes nucleoside diphosphates";   reactome:R-HSA-8851396 "NTPDase6 hydrolyzes nucleoside diphosphates";   reactome:R-HSA-8851550 "NTPDase8 hydrolyzes nucleoside diphosphates"


show annotations for term's descendants           Sort by:
nucleoside diphosphate phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CANT1 calcium activated nucleotidase 1 enables IEA InterPro
UniProt
RHEA		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000116 NCBI chr17:78,991,716...79,009,764
Ensembl chr17:78,991,716...79,009,867 		JBrowse link
G ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 enables IDA (PMID:10636909), (PMID:8529670), (PMID:8626624), (PMID:8955160), (PMID:8996251) UniProt PMID:8529670 PMID:8626624 PMID:8955160 PMID:8996251 PMID:10636909 NCBI chr10:95,694,186...95,877,266
Ensembl chr10:95,711,779...95,877,266 		JBrowse link
G ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 enables IEA Ensembl GO_REF:0000107 NCBI chr 9:137,048,107...137,054,061
Ensembl chr 9:137,048,107...137,054,061 		JBrowse link
G ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 enables IEA
IDA		 (PMID:10231536), (PMID:11300774) Ensembl
UniProt		 PMID:10231536 PMID:11300774 GO_REF:0000107 NCBI chr 3:40,387,184...40,428,744
Ensembl chr 3:40,387,184...40,428,744 		JBrowse link
G ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 enables IDA (PMID:10858452) UniProt PMID:10858452 NCBI chr 8:23,429,162...23,457,647
Ensembl chr 8:23,385,783...23,457,695 		JBrowse link
G ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 enables ISO
IDA
IEA		 (PMID:14529283) RGD
UniProt
Ensembl		 PMID:11042118 PMID:14529283 GO_REF:0000003 GO_REF:0000107 RGD:727304 NCBI chr20:25,195,712...25,228,075
Ensembl chr20:25,195,693...25,228,075 		JBrowse link
G ENTPD8 ectonucleoside triphosphate diphosphohydrolase 8 enables IEA Ensembl GO_REF:0000107 NCBI chr 9:137,434,364...137,441,357
Ensembl chr 9:137,434,364...137,441,816 		JBrowse link
G NUDT18 nudix hydrolase 18 enables IEA InterPro GO_REF:0000002 NCBI chr 8:22,106,878...22,110,482
Ensembl chr 8:22,105,748...22,109,419 		JBrowse link
G NUDT5 nudix hydrolase 5 enables IEA Ensembl GO_REF:0000107 NCBI chr10:12,165,330...12,195,891
Ensembl chr10:12,165,330...12,195,891 		JBrowse link
8-hydroxy-dADP phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NUDT18 nudix hydrolase 18 enables EXP
IDA		 (PMID:22556419) Reactome
UniProt		 PMID:22556419 NCBI chr 8:22,106,878...22,110,482
Ensembl chr 8:22,105,748...22,109,419 		JBrowse link
8-oxo-dGDP phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NUDT15 nudix hydrolase 15 enables EXP (PMID:22556419) Reactome PMID:22556419 NCBI chr13:48,037,726...48,052,755
Ensembl chr13:48,037,726...48,047,221 		JBrowse link
G NUDT18 nudix hydrolase 18 enables IDA
IBA
EXP
IEA		 (PMID:22556419) UniProt
GO_Central
Reactome
RHEA		 PMID:22556419 GO_REF:0000003 GO_REF:0000033 GO_REF:0000116 NCBI chr 8:22,106,878...22,110,482
Ensembl chr 8:22,105,748...22,109,419 		JBrowse link
G NUDT5 nudix hydrolase 5 enables IEA
IDA		 (PMID:19699693), (PMID:21389046) UniProt
RHEA		 PMID:19699693 PMID:21389046 GO_REF:0000003 GO_REF:0000116 NCBI chr10:12,165,330...12,195,891
Ensembl chr10:12,165,330...12,195,891 		JBrowse link
8-oxo-GDP phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NUDT18 nudix hydrolase 18 enables EXP
IBA
IEA
IDA		 (PMID:22556419) Reactome
GO_Central
RHEA
UniProt		 PMID:22556419 GO_REF:0000003 GO_REF:0000033 GO_REF:0000116 NCBI chr 8:22,106,878...22,110,482
Ensembl chr 8:22,105,748...22,109,419 		JBrowse link
G NUDT5 nudix hydrolase 5 enables IEA UniProt GO_REF:0000003 NCBI chr10:12,165,330...12,195,891
Ensembl chr10:12,165,330...12,195,891 		JBrowse link
ADP phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALPL alkaline phosphatase, biomineralization associated enables IEA RHEA GO_REF:0000116 NCBI chr 1:21,508,984...21,578,410
Ensembl chr 1:21,509,397...21,578,410 		JBrowse link
G CANT1 calcium activated nucleotidase 1 enables IDA (PMID:16835225) UniProt PMID:16835225 NCBI chr17:78,991,716...79,009,764
Ensembl chr17:78,991,716...79,009,867 		JBrowse link
G ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 enables ISO
IEA		 RGD
RHEA		 PMID:18841405 GO_REF:0000116 RGD:9685441 NCBI chr10:95,694,186...95,877,266
Ensembl chr10:95,711,779...95,877,266 		JBrowse link
G ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 ISO RGD PMID:16414200 RGD:9685525 NCBI chr 9:137,048,107...137,054,061
Ensembl chr 9:137,048,107...137,054,061 		JBrowse link
G ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 (inactive) enables IDA
IEA		 (PMID:10400613) UniProt
RHEA		 PMID:10400613 GO_REF:0000116 NCBI chr14:73,955,329...74,019,288
Ensembl chr14:73,958,010...74,019,399 		JBrowse link
G PGP phosphoglycolate phosphatase enables IEA Ensembl GO_REF:0000107 NCBI chr16:2,211,593...2,214,840
Ensembl chr16:2,211,593...2,214,840 		JBrowse link
G SLC25A42 solute carrier family 25 member 42 enables IDA (PMID:19429682) UniProt PMID:19429682 NCBI chr19:19,063,994...19,113,030
Ensembl chr19:19,063,994...19,113,030 		JBrowse link
CDP phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 enables IEA RHEA GO_REF:0000116 NCBI chr10:95,694,186...95,877,266
Ensembl chr10:95,711,779...95,877,266 		JBrowse link
G ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 enables IDA (PMID:10858452) UniProt PMID:10858452 NCBI chr 8:23,429,162...23,457,647
Ensembl chr 8:23,385,783...23,457,695 		JBrowse link
G ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 (inactive) enables IDA
IEA		 (PMID:10400613) UniProt
RHEA		 PMID:10400613 GO_REF:0000116 NCBI chr14:73,955,329...74,019,288
Ensembl chr14:73,958,010...74,019,399 		JBrowse link
G ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 enables IDA
IEA		 (PMID:14529283) UniProt
Ensembl		 PMID:14529283 GO_REF:0000107 NCBI chr20:25,195,712...25,228,075
Ensembl chr20:25,195,693...25,228,075 		JBrowse link
dIDP phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NUDT16 nudix hydrolase 16 enables IEA RHEA GO_REF:0000116 NCBI chr 3:131,381,671...131,388,830
Ensembl chr 3:131,381,671...131,388,830 		JBrowse link
GDP phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CANT1 calcium activated nucleotidase 1 enables IDA
IBA		 (PMID:16835225) UniProt
GO_Central		 PMID:16835225 GO_REF:0000033 NCBI chr17:78,991,716...79,009,764
Ensembl chr17:78,991,716...79,009,867 		JBrowse link
G ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 enables IEA
IBA		 RHEA
GO_Central		 GO_REF:0000033 GO_REF:0000116 NCBI chr10:95,694,186...95,877,266
Ensembl chr10:95,711,779...95,877,266 		JBrowse link
G ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 enables IBA GO_Central GO_REF:0000033 NCBI chr 9:137,048,107...137,054,061
Ensembl chr 9:137,048,107...137,054,061 		JBrowse link
G ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 enables IBA GO_Central GO_REF:0000033 NCBI chr 3:40,387,184...40,428,744
Ensembl chr 3:40,387,184...40,428,744 		JBrowse link
G ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 enables IEA
IBA
IDA		 (PMID:10858452) UniProt
GO_Central
RHEA		 PMID:10858452 GO_REF:0000003 GO_REF:0000033 GO_REF:0000116 NCBI chr 8:23,429,162...23,457,647
Ensembl chr 8:23,385,783...23,457,695 		JBrowse link
G ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 (inactive) enables IEA
IBA
IDA
ISS		 (PMID:10400613), (PMID:15698960) UniProt
GO_Central
RHEA		 PMID:10400613 PMID:15698960 GO_REF:0000003 GO_REF:0000024 GO_REF:0000033 GO_REF:0000116 NCBI chr14:73,955,329...74,019,288
Ensembl chr14:73,958,010...74,019,399 		JBrowse link
G ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 enables IDA
IBA
IEA		 (PMID:14529283) UniProt
GO_Central
RHEA
Ensembl		 PMID:14529283 GO_REF:0000033 GO_REF:0000107 GO_REF:0000116 NCBI chr20:25,195,712...25,228,075
Ensembl chr20:25,195,693...25,228,075 		JBrowse link
G ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7 enables IBA GO_Central GO_REF:0000033 NCBI chr10:99,659,509...99,711,241
Ensembl chr10:99,659,509...99,711,241 		JBrowse link
G ENTPD8 ectonucleoside triphosphate diphosphohydrolase 8 enables IBA GO_Central GO_REF:0000033 NCBI chr 9:137,434,364...137,441,357
Ensembl chr 9:137,434,364...137,441,816 		JBrowse link
G GBP1 guanylate binding protein 1 enables IDA
IEA		 (PMID:16511497), (PMID:28645896), (PMID:7512561) UniProt
RHEA		 PMID:7512561 PMID:16511497 PMID:28645896 GO_REF:0000116 NCBI chr 1:89,052,319...89,065,208
Ensembl chr 1:89,051,882...89,065,360 		JBrowse link
IDP phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 enables IEA RHEA GO_REF:0000116 NCBI chr10:95,694,186...95,877,266
Ensembl chr10:95,711,779...95,877,266 		JBrowse link
G ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 (inactive) enables IDA
IEA		 (PMID:15698960) UniProt
RHEA		 PMID:15698960 GO_REF:0000116 NCBI chr14:73,955,329...74,019,288
Ensembl chr14:73,958,010...74,019,399 		JBrowse link
G ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 enables IEA
IDA		 (PMID:14529283) RHEA
UniProt
Ensembl		 PMID:14529283 GO_REF:0000107 GO_REF:0000116 NCBI chr20:25,195,712...25,228,075
Ensembl chr20:25,195,693...25,228,075 		JBrowse link
G NUDT16 nudix hydrolase 16 enables IEA
IDA		 (PMID:20385596) RHEA
UniProt		 PMID:20385596 GO_REF:0000003 GO_REF:0000116 NCBI chr 3:131,381,671...131,388,830
Ensembl chr 3:131,381,671...131,388,830 		JBrowse link
UDP phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CANT1 calcium activated nucleotidase 1 enables IBA GO_Central GO_REF:0000033 NCBI chr17:78,991,716...79,009,764
Ensembl chr17:78,991,716...79,009,867 		JBrowse link
G ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 enables IEA
IBA		 RHEA
GO_Central		 GO_REF:0000033 GO_REF:0000116 NCBI chr10:95,694,186...95,877,266
Ensembl chr10:95,711,779...95,877,266 		JBrowse link
G ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 enables IBA GO_Central GO_REF:0000033 NCBI chr 9:137,048,107...137,054,061
Ensembl chr 9:137,048,107...137,054,061 		JBrowse link
G ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 enables IBA GO_Central GO_REF:0000033 NCBI chr 3:40,387,184...40,428,744
Ensembl chr 3:40,387,184...40,428,744 		JBrowse link
G ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 enables IEA
IBA
IDA		 (PMID:10858452), (PMID:9556635) RHEA
GO_Central
UniProt		 PMID:9556635 PMID:10858452 GO_REF:0000033 GO_REF:0000116 NCBI chr 8:23,429,162...23,457,647
Ensembl chr 8:23,385,783...23,457,695 		JBrowse link
G ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 (inactive) enables ISS
IBA
IEA
IDA		 (PMID:10400613), (PMID:15698960) UniProt
GO_Central
RHEA		 PMID:10400613 PMID:15698960 GO_REF:0000024 GO_REF:0000033 GO_REF:0000116 NCBI chr14:73,955,329...74,019,288
Ensembl chr14:73,958,010...74,019,399 		JBrowse link
G ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 enables IDA
IBA
IEA		 (PMID:14529283) UniProt
GO_Central
Ensembl
RHEA		 PMID:14529283 GO_REF:0000033 GO_REF:0000107 GO_REF:0000116 NCBI chr20:25,195,712...25,228,075
Ensembl chr20:25,195,693...25,228,075 		JBrowse link
G ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7 enables IBA GO_Central GO_REF:0000033 NCBI chr10:99,659,509...99,711,241
Ensembl chr10:99,659,509...99,711,241 		JBrowse link
G ENTPD8 ectonucleoside triphosphate diphosphohydrolase 8 enables IBA GO_Central GO_REF:0000033 NCBI chr 9:137,434,364...137,441,357
Ensembl chr 9:137,434,364...137,441,816 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 19551
    catalytic activity 6024
      hydrolase activity 2641
        hydrolase activity, acting on acid anhydrides 852
          hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 852
            pyrophosphatase activity 848
              nucleoside diphosphate phosphatase activity 17
                8-hydroxy-dADP phosphatase activity 1
                8-oxo-GDP phosphatase activity 2
                8-oxo-dADP diphosphate phosphatase activity 0
                8-oxo-dGDP phosphatase activity 3
                ADP phosphatase activity 7
                CDP phosphatase activity 4
                GDP phosphatase activity 10
                IDP phosphatase activity 4
                UDP phosphatase activity 9
                dIDP phosphatase activity 1
paths to the root