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ONTOLOGY REPORT - ANNOTATIONS

Term:tRNA (cytidine) methyltransferase activity
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Accession:GO:0016427 term browser browse the term
Definition:Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing methylcytosine.
Synonyms:exact_synonym: tRNA (cytosine) methyltransferase activity


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tRNA (cytidine) methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FTSJ1 FtsJ RNA 2'-O-methyltransferase 1 enables IEA UniProt GO_REF:0000117 NCBI chr  X:48,476,021...48,486,364
Ensembl chr  X:48,476,021...48,486,364 		JBrowse link
G METTL2B methyltransferase 2B, tRNA N3-cytidine enables IMP (PMID:21518805) UniProt PMID:21518805 NCBI chr 7:128,476,748...128,506,602
Ensembl chr 7:128,476,729...128,506,602 		JBrowse link
tRNA (cytidine(32)-2'-O)-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FTSJ1 FtsJ RNA 2'-O-methyltransferase 1 enables IEA
IMP		 (PMID:36720500) UniProt
RHEA		 PMID:36720500 GO_REF:0000003 GO_REF:0000116 NCBI chr  X:48,476,021...48,486,364
Ensembl chr  X:48,476,021...48,486,364 		JBrowse link
tRNA (cytidine-3-)-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G METTL2A methyltransferase 2A, tRNA N3-cytidine enables IMP
IEA
IBA
IDA		 (PMID:28655767)
(PMID:34268557)		 UniProt
TreeGrafter
GO_Central		 PMID:28655767 PMID:34268557 GO_REF:0000033 GO_REF:0000118 NCBI chr17:62,423,897...62,453,385
Ensembl chr17:62,423,875...62,453,385 		JBrowse link
G METTL2B methyltransferase 2B, tRNA N3-cytidine enables IMP
IBA		 (PMID:28655767) UniProt
GO_Central		 PMID:28655767 GO_REF:0000033 NCBI chr 7:128,476,748...128,506,602
Ensembl chr 7:128,476,729...128,506,602 		JBrowse link
G METTL6 methyltransferase 6, tRNA N3-cytidine enables IEA
IDA		 (PMID:32923617), (PMID:34268557), (PMID:34862464), (PMID:34922197) Ensembl
UniProt		 PMID:32923617 PMID:34268557 PMID:34862464 PMID:34922197 GO_REF:0000107 NCBI chr 3:15,381,275...15,427,643
Ensembl chr 3:15,381,275...15,440,566 		JBrowse link
G METTL8 methyltransferase 8, tRNA N3-cytidine enables IDA
IEA
IBA		 (PMID:34774131), (PMID:35017528) UniProt
TreeGrafter
GO_Central		 PMID:34774131 PMID:35017528 GO_REF:0000033 GO_REF:0000118 NCBI chr 2:171,315,746...171,434,772
Ensembl chr 2:171,315,746...171,434,802 		JBrowse link
tRNA (cytidine-5-)-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NSUN2 NOP2/Sun RNA methyltransferase 2 enables IEA
IBA
IDA
EXP		 (PMID:17071714), (PMID:31287866), (PMID:34556860) Ensembl
GO_Central
UniProt
Reactome
InterPro		 PMID:17071714 PMID:31287866 PMID:34556860 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:6,599,239...6,633,044
Ensembl chr 5:6,599,239...6,633,291 		JBrowse link
G NSUN3 NOP2/Sun RNA methyltransferase 3 enables IDA (PMID:27214402), (PMID:27356879), (PMID:27497299) UniProt PMID:27214402 PMID:27356879 PMID:27497299 NCBI chr 3:94,063,061...94,131,832
Ensembl chr 3:94,062,980...94,131,832 		JBrowse link
G NSUN4 NOP2/Sun RNA methyltransferase 4 enables IEA RHEA GO_REF:0000116 NCBI chr 1:46,340,807...46,385,199
Ensembl chr 1:46,340,789...46,365,152 		JBrowse link
G NSUN6 NOP2/Sun RNA methyltransferase 6 enables EXP
IDA		 (PMID:26160102)
(PMID:26160102), (PMID:27703015), (PMID:28531330), (PMID:37226891)		 Reactome
GO_Central		 PMID:26160102 PMID:27703015 PMID:28531330 PMID:37226891 NCBI chr10:18,545,561...18,659,327
Ensembl chr10:18,545,561...18,659,285 		JBrowse link
G TRDMT1 tRNA aspartic acid methyltransferase 1 enables EXP
IDA
IEA
ISS		 (PMID:16424344), (PMID:18567810) Reactome
UniProt
Ensembl		 PMID:16424344 PMID:18567810 GO_REF:0000024 GO_REF:0000107 NCBI chr10:17,137,336...17,201,672
Ensembl chr10:17,137,336...17,202,054 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 19488
    catalytic activity 5987
      catalytic activity, acting on a nucleic acid 655
        catalytic activity, acting on RNA 419
          RNA methyltransferase activity 68
            tRNA methyltransferase activity 34
              tRNA (cytidine) methyltransferase activity 10
                tRNA (cytidine(32)-2'-O)-methyltransferase activity 1
                tRNA (cytidine(34)-2'-O)-methyltransferase activity 0
                tRNA (cytidine(56)-2'-O)-methyltransferase activity 0
                tRNA (cytidine-3-)-methyltransferase activity 4
                tRNA (cytidine-5-)-methyltransferase activity 5
Path 2
Term Annotations click to browse term
  molecular_function 19488
    catalytic activity 5987
      transferase activity 2465
        transferase activity, transferring one-carbon groups 238
          methyltransferase activity 228
            RNA methyltransferase activity 68
              tRNA methyltransferase activity 34
                tRNA (cytidine) methyltransferase activity 10
                  tRNA (cytidine(32)-2'-O)-methyltransferase activity 1
                  tRNA (cytidine(34)-2'-O)-methyltransferase activity 0
                  tRNA (cytidine(56)-2'-O)-methyltransferase activity 0
                  tRNA (cytidine-3-)-methyltransferase activity 4
                  tRNA (cytidine-5-)-methyltransferase activity 5
paths to the root