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Gene: FTSJ1 (FtsJ RNA 2'-O-methyltransferase 1) Homo sapiens
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Symbol: FTSJ1
Name: FtsJ RNA 2'-O-methyltransferase 1
Description: Exhibits tRNA (cytosine-2'-O-)-methyltransferase activity and tRNA (guanosine-2'-O-)-methyltransferase activity. Predicted to be involved in cytoplasmic translation and tRNA methylation. Predicted to localize to the cytoplasm. Implicated in non-syndromic X-linked intellectual disability.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 2'-O-ribose RNA methyltransferase TRM7 homolog; CDLIV; cell division protein; FtsJ homolog 1; FtsJ RNA methyltransferase homolog 1; FtsJ RNA methyltransferase homolog 1 (E. coli); FtsJ-like protein 1; JM23; mental retardation, X-linked 44; mental retardation, X-linked 9; MRX44; MRX9; putative ribosomal RNA methyltransferase 1; putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; rRNA (uridine-2'-O-)-methyltransferase; SPB1; TRM7; TRMT7; tRNA methyltransferase 7 homolog
Orthologs:
Mus musculus (house mouse) : Ftsj1 (FtsJ RNA methyltransferase homolog 1 (E. coli))  MGI  Alliance
Rattus norvegicus (Norway rat) : Ftsj1 (FtsJ RNA 2'-O-methyltransferase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ftsj1 (FtsJ RNA 2'-O-methyltransferase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : FTSJ1 (FtsJ RNA 2'-O-methyltransferase 1)
Canis lupus familiaris (dog) : FTSJ1 (FtsJ RNA 2'-O-methyltransferase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ftsj1 (FtsJ RNA 2'-O-methyltransferase 1)
Sus scrofa (pig) : FTSJ1 (FtsJ RNA 2'-O-methyltransferase 1)
Chlorocebus sabaeus (African green monkey) : FTSJ1 (FtsJ RNA 2'-O-methyltransferase 1)
Heterocephalus glaber (naked mole-rat) : Ftsj1 (FtsJ RNA 2'-O-methyltransferase 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 EnsemblX48,476,021 - 48,486,364 (+)Ensembl
GRCh38X48,476,021 - 48,486,364 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X48,334,454 - 48,344,752 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X48,219,493 - 48,229,696 (+)NCBINCBI36hg18NCBI36
Build 34X48,090,802 - 48,101,006NCBI
CeleraX53,320,980 - 53,331,186 (-)NCBI
Cytogenetic MapXp11.23NCBI
HuRefX45,998,280 - 46,007,952 (+)NCBIHuRef
CHM1_1X48,365,666 - 48,376,012 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on FTSJ1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1345273
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-02-11
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.