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ONTOLOGY REPORT - ANNOTATIONS

Term:ganglioside biosynthetic process via lactosylceramide
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Accession:GO:0010706 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of gangliosides that begins with the formation of lactosylceramides, Gal-beta-(1->4)-Glc-beta-(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group.
Synonyms:exact_synonym: ganglioside biosynthesis via lactosylceramide biosynthesis
 related_synonym: biosynthesis of lactosylceramide precursor to ganglioside;   lactosylceramide biosynthesis leading to ganglioside;   lactosylceramide biosynthetic process leading to ganglioside


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ganglioside biosynthetic process via lactosylceramide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B4galt5 beta-1,4-galactosyltransferase 5 involved_in ISO (MGI:6196231|PMID:30114188) RGD PMID:30114188 MGI:6196231 NCBI chr 3:156,018,056...156,033,983
Ensembl chr 3:156,018,053...156,070,074 		JBrowse link
G B4galt6 beta-1,4-galactosyltransferase 6 involved_in ISS
ISO		 GO_REF:0000024
(MGI:6196231|PMID:30114188)		 UniProt
RGD		 PMID:30114188 GO_REF:0000024 MGI:6196231 NCBI chr18:11,958,382...12,015,247
Ensembl chr18:11,958,390...12,015,247 		JBrowse link
G St3gal1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 involved_in ISO
IBA		 (PMID:8027041)
(MGI:65558|PMID:8144500)
GO_REF:0000033		 RGD
GO_Central		 PMID:8027041 PMID:8144500 GO_REF:0000033 MGI:65558 NCBI chr 7:98,845,270...98,913,409
Ensembl chr 7:98,845,270...98,913,236 		JBrowse link
G St3gal2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 involved_in IDA
ISO
IEA
IBA		 PMID:8144500
(PMID:8920913)
(MGI:6467685|PMID:22735313), (MGI:65558|PMID:8144500)
GO_REF:0000117
GO_REF:0000033		 RGD
UniProt
GO_Central		 PMID:8144500 PMID:8920913 PMID:22735313 PMID:8144500 GO_REF:0000033 GO_REF:0000117 MGI:6467685 MGI:65558, RGD:68307 NCBI chr19:38,888,851...38,939,874
Ensembl chr19:38,923,999...38,939,869 		JBrowse link
G St3gal3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 involved_in IEA
ISO		 GO_REF:0000107
(MGI:6467685|PMID:22735313)		 Ensembl
RGD		 PMID:22735313 GO_REF:0000107 MGI:6467685 NCBI chr 5:131,470,348...131,670,794
Ensembl chr 5:131,470,348...131,670,810 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19692
    metabolic process 11455
      amide metabolic process 435
        ceramide metabolic process 109
          ganglioside metabolic process 27
            ganglioside biosynthetic process 16
              ganglioside biosynthetic process via lactosylceramide 5
Path 2
Term Annotations click to browse term
  biological_process 19692
    metabolic process 11455
      primary metabolic process 10015
        lipid metabolic process 1453
          cellular lipid metabolic process 1074
            membrane lipid metabolic process 207
              sphingolipid metabolic process 155
                glycosphingolipid metabolic process 58
                  ganglioside metabolic process 27
                    ganglioside biosynthetic process 16
                      ganglioside biosynthetic process via lactosylceramide 5
paths to the root