ONTOLOGY REPORT - ANNOTATIONS
Term: respiratory chain complex IV assembly
Accession: GO:0008535
browse the term
Definition: The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase), the terminal member of the respiratory chain of the mitochondrion and some aerobic bacteria. Cytochrome c oxidases are multi-subunit enzymes containing from 13 subunits in the mammalian mitochondrial form to 3-4 subunits in the bacterial forms.
Synonyms: exact_synonym: cytochrome c oxidase complex assembly
broad_synonym: cytochrome c oxidase biogenesis
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LOC102022268
protoheme IX farnesyltransferase, mitochondrial
involved_in
ISO
(PMID:14607829)
HGNC-UCL
PMID:14607829
NCBI chrNW_004955467:3,294,200...3,415,778
Ensembl chrNW_004955467:3,292,018...3,415,778
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LOC102025739
mitochondrial inner membrane protein COX18
involved_in
ISO
(PMID:16911509)
UniProt
PMID:16911509
NCBI chrNW_004955447:382,631...390,399
Ensembl chrNW_004955447:382,679...390,037
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LOC102028200
cytochrome c oxidase assembly factor 6 homolog
involved_in
ISO
(PMID:25959673), (PMID:26160915) (PMID:24549041)
UniProt
PMID:24549041 PMID:25959673 PMID:26160915
NCBI chrNW_004955492:5,316,594...5,324,913
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LOC106146232
protein SCO2 homolog, mitochondrial
acts_upstream_of_or_within
ISO
(PMID:19837698)
MGI
PMID:19837698
NCBI chrNW_004955413:33,503,882...33,505,417
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Slc25a46
solute carrier family 25 member 46
acts_upstream_of_or_within
ISO
(PMID:27390132)
UniProt
PMID:27390132
NCBI chrNW_004955418:4,316,790...4,342,748
Ensembl chrNW_004955418:4,316,790...4,341,973
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Apopt1
apoptogenic 1, mitochondrial
involved_in
ISO
(PMID:25175347) (PMID:30552096) (MGI:6355662|PMID:30552096)
UniProt
PMID:25175347 PMID:30552096
MGI:6355662
NCBI chrNW_004955538:2,415,781...2,432,742
Ensembl chrNW_004955538:2,415,604...2,434,658
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CUNH12orf73
chromosome unknown C12orf73 homolog
involved_in
ISO
(PMID:34969438)
UniProt
PMID:34969438
NCBI chrNW_004955405:38,651,787...38,656,564
Ensembl chrNW_004955405:38,651,787...38,656,564
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Fastkd3
FAST kinase domains 3
involved_in
ISO
(PMID:27789713)
UniProt
PMID:27789713
NCBI chrNW_004955504:5,401,956...5,412,216
Ensembl chrNW_004955504:5,400,544...5,411,401
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LOC102007967
mitochondrial chaperone BCS1
involved_in
ISO
(PMID:18628306)
UniProt
PMID:18628306
NCBI chrNW_004955453:14,762,237...14,766,693
Ensembl chrNW_004955453:14,762,237...14,766,383
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LOC102011844
cytochrome c oxidase assembly factor 1 homolog
involved_in
ISO
(PMID:23260140)
UniProt
PMID:23260140
NCBI chrNW_004955460:182,778...285,053
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LOC102015156
cytochrome c oxidase assembly protein COX14
involved_in
ISO
(PMID:22243966)
UniProt
PMID:22243966
NCBI chrNW_004955547:690,167...690,777
Ensembl chrNW_004955547:676,342...690,777
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LOC102016346
cytochrome c oxidase protein 20 homolog
involved_in
ISO
(PMID:23125284), (PMID:24403053)
UniProt
PMID:23125284 PMID:24403053
NCBI chrNW_004955406:7,994,226...8,002,639
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LOC102021151
cytochrome c oxidase copper chaperone
involved_in
ISO
(PMID:19393246) (PMID:37813994)
CAFA UniProt
PMID:19393246 PMID:37813994
NCBI chrNW_004955427:19,376,482...19,384,270
Ensembl chrNW_004955427:19,376,482...19,384,270
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LOC102023128
cytochrome c oxidase assembly protein COX16 homolog, mitochondrial
involved_in
ISO
(PMID:29381136) (PMID:29355485)
UniProt
PMID:29355485 PMID:29381136
NCBI chrNW_004955466:130,341...142,969
Ensembl chrNW_004955466:130,341...142,969
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LOC102024671
translational activator of cytochrome c oxidase 1
acts_upstream_of_or_within
ISO
(PMID:27319982)
MGI
PMID:27319982
NCBI chrNW_004955478:8,198,563...8,204,820
Ensembl chrNW_004955478:8,199,244...8,204,577
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LOC102025739
mitochondrial inner membrane protein COX18
involved_in
ISO
(PMID:28330871)
UniProt
PMID:28330871
NCBI chrNW_004955447:382,631...390,399
Ensembl chrNW_004955447:382,679...390,037
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LOC102025968
cytochrome c oxidase assembly factor 3 homolog, mitochondrial
involved_in
ISO
(PMID:23260140)
UniProt
PMID:23260140
NCBI chrNW_004955451:16,607,495...16,608,732
Ensembl chrNW_004955451:16,607,895...16,608,647
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LOC102030058
protein SCO1 homolog, mitochondrial
involved_in acts_upstream_of_or_within
ISO
(PMID:15229189) (PMID:25683716)
UniProt MGI
PMID:15229189 PMID:25683716
NCBI chrNW_004955467:6,519,873...6,535,321
Ensembl chrNW_004955467:6,519,873...6,537,753
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LOC106146232
protein SCO2 homolog, mitochondrial
involved_in
ISO
(PMID:15229189)
UniProt
PMID:15229189
NCBI chrNW_004955413:33,503,882...33,505,417
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Smim20
small integral membrane protein 20
involved_in
ISO
(PMID:26321642)
UniProt
PMID:26321642
NCBI chrNW_004955443:19,242,776...19,254,002
Ensembl chrNW_004955443:19,243,419...19,253,798
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Smim4
small integral membrane protein 4
involved_in
ISO
(PMID:34969438)
UniProt
PMID:34969438
NCBI chrNW_004956313:1,988...5,240
Ensembl chrNW_004956313:1,988...5,240
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Stmp1
short transmembrane mitochondrial protein 1
involved_in
ISO
(PMID:35450818)
UniProt
PMID:35450818
NCBI chrNW_004955494:7,063,374...7,077,052
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Surf1
surfeit 1
involved_in
ISO
(PMID:24027061)
UniProt
PMID:24027061
NCBI chrNW_004955513:2,707,877...2,711,606
Ensembl chrNW_004955513:2,707,951...2,711,566
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Timm21
translocase of inner mitochondrial membrane 21
involved_in
ISO
(PMID:23260140)
UniProt
PMID:23260140
NCBI chrNW_004955402:57,586,651...57,598,817
Ensembl chrNW_004955402:57,586,998...57,599,869
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Tmem223
transmembrane protein 223
involved_in
ISO
(PMID:34969438)
UniProt
PMID:34969438
NCBI chrNW_004955599:450,518...451,947
Ensembl chrNW_004955599:450,971...451,880
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