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ONTOLOGY REPORT - ANNOTATIONS

Term:spectrin
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Accession:GO:0008091 term browser browse the term
Definition:Membrane associated dimeric protein (240 and 220 kDa) of erythrocytes. Forms a complex with ankyrin, actin and probably other components of the membrane cytoskeleton, so that there is a mesh of proteins underlying the plasma membrane, potentially restricting the lateral mobility of integral proteins.
Synonyms:xref: NIF_Subcellular:sao536287099;   Wikipedia:Spectrin

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spectrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prkcb protein kinase C beta part_of ISO (MGI:1346761|PMID:10534118) CACAO PMID:10534118 MGI:1346761 NCBI chrNW_004955493:2,395,494...2,710,522
Ensembl chrNW_004955493:2,395,109...2,710,934 		JBrowse link
G Spta1 spectrin alpha, erythrocytic 1 part_of ISO (PMID:6234993) MGI PMID:6234993 NCBI chrNW_004955468:10,472,601...10,545,402
Ensembl chrNW_004955468:10,472,671...10,545,313 		JBrowse link
G Sptbn2 spectrin beta, non-erythrocytic 2 part_of ISO (PMID:9826670) UniProt PMID:9826670 NCBI chrNW_004955422:18,659,489...18,699,338
Ensembl chrNW_004955422:18,659,489...18,699,338 		JBrowse link
G Sptbn4 spectrin beta, non-erythrocytic 4 part_of ISO (PMID:11086001) UniProt PMID:11086001 NCBI chrNW_004955578:730,916...813,740
Ensembl chrNW_004955578:731,814...810,065 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 12560
    protein-containing complex 4414
      spectrin 4
Path 2
Term Annotations click to browse term
  cellular_component 12560
    cellular anatomical entity 12401
      organelle 9810
        non-membrane-bounded organelle 3689
          intracellular non-membrane-bounded organelle 3687
            cytoskeleton 1695
              actin cytoskeleton 409
                cortical actin cytoskeleton 68
                  spectrin 4
paths to the root