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ONTOLOGY REPORT - ANNOTATIONS

Term:mitochondrial DNA replication
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Accession:GO:0006264 term browser browse the term
Definition:The process in which new strands of DNA are synthesized in the mitochondrion.
Synonyms:exact_synonym: mtDNA replication;   replication of mitochondrial DNA
 related_synonym: mitochondrial DNA synthesis;   mtDNA synthesis
 only_in_taxon: NCBITaxon:2759 ! Eukaryota


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mitochondrial DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNA2 DNA replication helicase/nuclease 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:19,626,001...19,683,819
Ensembl chr 4:19,626,977...19,684,660 		JBrowse link
G DNAJA3 DnaJ heat shock protein family (Hsp40) member A3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16327803) Ensembl
MGI		 PMID:16327803 GO_REF:0000107 NCBI chr 6:36,921,941...36,967,718
Ensembl chr 6:36,917,858...36,967,689 		JBrowse link
G MGME1 mitochondrial genome maintenance exonuclease 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:5,068,147...5,083,941 JBrowse link
G POLG DNA polymerase gamma, catalytic subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15888483) Ensembl
MGI
InterPro		 PMID:15888483 GO_REF:0000002 GO_REF:0000107 NCBI chr 3:52,357,062...52,373,768
Ensembl chr 3:52,357,068...52,421,544 		JBrowse link
G POLG2 DNA polymerase gamma 2, accessory subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23197651) Ensembl
MGI		 PMID:23197651 GO_REF:0000107 NCBI chr 9:12,258,188...12,298,376
Ensembl chr 9:12,269,990...12,298,272 		JBrowse link
G PRIMPOL primase and DNA directed polymerase involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:45,861,244...45,920,183
Ensembl chr16:45,856,042...45,918,761 		JBrowse link
G RNASEH1 ribonuclease H1 acts_upstream_of_or_within ISO (PMID:12667461) MGI PMID:12667461 NCBI chr17:2,117,446...2,127,893
Ensembl chr17:2,117,446...2,127,893 		JBrowse link
G RRM1 ribonucleotide reductase catalytic subunit M1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:26,595,838...26,631,476
Ensembl chr21:26,595,914...26,631,135 		JBrowse link
G RRM2B ribonucleotide reductase regulatory TP53 inducible subunit M2B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17486094) Ensembl
MGI		 PMID:17486094 GO_REF:0000107 NCBI chr13:3,774,725...3,838,576
Ensembl chr13:3,799,025...3,837,934 		JBrowse link
G SSBP1 single stranded DNA binding protein 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr16:7,445,351...7,461,513
Ensembl chr16:7,451,444...7,461,464 		JBrowse link
G TEFM transcription elongation factor, mitochondrial NOT|involved_in ISO (PMID:21278163) UniProt PMID:21278163 NCBI chr 9:40,860,850...40,868,020
Ensembl chr 9:40,860,938...40,868,020 		JBrowse link
G TK2 thymidine kinase 2 acts_upstream_of_or_within ISO (PMID:18434326) MGI PMID:18434326 NCBI chr 5:82,730,514...82,758,153
Ensembl chr 5:82,729,150...82,756,457 		JBrowse link
G TWNK twinkle mtDNA helicase involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:13,672,772...13,680,732
Ensembl chr28:13,676,304...13,680,044 		JBrowse link
negative regulation of mitochondrial DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATG7 autophagy related 7 ISO RGD PMID:23800874 RGD:11557986 NCBI chr20:6,916,354...7,154,849
Ensembl chr20:6,916,515...7,154,800 		JBrowse link
G LIG3 DNA ligase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:38,346,275...38,366,634
Ensembl chr 9:38,346,199...38,366,193 		JBrowse link
positive regulation of mitochondrial DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENDOG endonuclease G involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:54,809,470...54,812,795
Ensembl chr 9:54,809,530...54,813,042 		JBrowse link
G MTNAP1 mitochondrial nucleoid associated protein 1 involved_in ISO (PMID:37676315) UniProt PMID:37676315 NCBI chr 9:6,937,549...6,948,439
Ensembl chr 9:6,937,588...6,947,403 		JBrowse link
G SSBP1 single stranded DNA binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:7,445,351...7,461,513
Ensembl chr16:7,451,444...7,461,464 		JBrowse link
regulation of mitochondrial DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G METTL4 methyltransferase 4, N6-adenosine involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:69,229,717...69,268,223
Ensembl chr 7:69,191,223...69,267,683 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17099
    cellular process 16594
      metabolic process 10706
        macromolecule metabolic process 8777
          nucleic acid metabolic process 4580
            DNA metabolic process 888
              mitochondrial DNA metabolic process 27
                mitochondrial DNA replication 18
                  DNA synthesis involved in mitochondrial DNA replication 0
                  kinetoplast DNA replication 0
                  negative regulation of mitochondrial DNA replication 2
                  positive regulation of mitochondrial DNA replication 3
                  regulation of mitochondrial DNA replication + 6
Path 2
Term Annotations click to browse term
  biological_process 17099
    cellular process 16594
      metabolic process 10706
        primary metabolic process 9411
          nucleobase-containing compound metabolic process 5139
            nucleic acid metabolic process 4580
              DNA metabolic process 888
                DNA replication 256
                  DNA-templated DNA replication 143
                    mitochondrial DNA replication 18
                      DNA synthesis involved in mitochondrial DNA replication 0
                      kinetoplast DNA replication 0
                      negative regulation of mitochondrial DNA replication 2
                      positive regulation of mitochondrial DNA replication 3
                      regulation of mitochondrial DNA replication + 6
paths to the root