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ONTOLOGY REPORT - ANNOTATIONS

Term:eukaryotic translation initiation factor 2B complex
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Accession:GO:0005851 term browser browse the term
Definition:A multisubunit guanine nucleotide exchange factor which catalyzes the exchange of GDP bound to initiation factor eIF2 for GTP, generating active eIF2-GTP. In humans, it is composed of five subunits, alpha, beta, delta, gamma and epsilon.
Synonyms:exact_synonym: eIF-2B;   eif2B
 only_in_taxon: NCBITaxon:2759 ! Eukaryota


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eukaryotic translation initiation factor 2B complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2b1 eukaryotic translation initiation factor 2B subunit alpha part_of IDA
IBA
ISO
IEA
ISS		 GO_REF:0000033
(PMID:11323413), (PMID:15060152), (PMID:27023709)
GO_REF:0000107
GO_REF:0000024		 GO_Central
RGD
Ensembl
UniProt		 PMID:11323413 PMID:15060152 PMID:27023709 PMID:9631509 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107, RGD:11041878 NCBI chr12:32,025,593...32,033,848
Ensembl chr12:32,025,557...32,046,601 		JBrowse link
G Eif2b2 eukaryotic translation initiation factor 2B subunit beta part_of IDA
IBA
ISO
ISS
IEA		 GO_REF:0000033
(PMID:11323413), (PMID:15060152), (PMID:27023709)
GO_REF:0000024
GO_REF:0000107		 GO_Central
RGD
UniProt
Ensembl		 PMID:11323413 PMID:15060152 PMID:27023709 PMID:9631509 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107, RGD:11041878 NCBI chr 6:104,866,926...104,873,351
Ensembl chr 6:104,866,753...104,873,353 		JBrowse link
G Eif2b3 eukaryotic translation initiation factor 2B subunit gamma part_of IDA
IBA
ISO
IEA
ISS		 GO_REF:0000033
(PMID:11323413), (PMID:15060152), (PMID:27023709)
GO_REF:0000107
GO_REF:0000024		 GO_Central
RGD
Ensembl
UniProt		 PMID:11323413 PMID:15060152 PMID:27023709 PMID:9139680 PMID:9631509 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000107, RGD:1581073, RGD:11041878, RGD:1581075 NCBI chr 5:130,492,167...130,558,692
Ensembl chr 5:130,492,220...130,563,332 		JBrowse link
G Eif2b4 eukaryotic translation initiation factor 2B subunit delta part_of IDA
ISO
IEA
NAS
ISS		 (PMID:11323413), (PMID:15060152), (PMID:27023709)
GO_REF:0000107
PMID:9582312
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:11323413 PMID:15060152 PMID:27023709 PMID:9139680 PMID:9582312 More... GO_REF:0000024 GO_REF:0000107, RGD:1581073, RGD:1581075, RGD:11041878, RGD:1581075 NCBI chr 6:25,183,177...25,188,832
Ensembl chr 6:25,183,186...25,188,829 		JBrowse link
G Eif2b5 eukaryotic translation initiation factor 2B subunit epsilon part_of IDA
ISS
ISO
IBA		 GO_REF:0000024
(PMID:11323413), (PMID:15060152), (PMID:27023709)
GO_REF:0000033		 UniProt
RGD
GO_Central		 PMID:11323413 PMID:15060152 PMID:27023709 PMID:9139680 PMID:9582312 More... GO_REF:0000024 GO_REF:0000033, RGD:1581073, RGD:1581075, RGD:11041878 NCBI chr11:80,394,433...80,404,468
Ensembl chr11:80,394,433...80,404,419 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20624
    protein-containing complex 6602
      eukaryotic translation initiation factor 2B complex 5
Path 2
Term Annotations click to browse term
  cellular_component 20624
    cellular anatomical entity 20386
      intracellular anatomical structure 15010
        cytoplasm 11694
          eukaryotic translation initiation factor 2B complex 5
paths to the root