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ONTOLOGY REPORT - ANNOTATIONS

Term:D-glucose:sodium symporter activity
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Accession:GO:0005412 term browser browse the term
Definition:Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: D-glucose(out) + Na+(out) = D-glucose(in) + Na+(in).
Synonyms:exact_synonym: glucose:sodium symporter activity
 xref: MetaCyc:RXN-22596;   Reactome:R-HSA-5656356 "Defective SLC5A1 does not cotransport Glc and Na+";   Reactome:R-HSA-5658163 "Defective SLC5A2 does not cotransport Glc and Na+ from extracellular region to cytosol";   reactome:R-HSA-189208 "SLC5A2 cotransports Na+ and glucose from extracellular region to cytosol";   reactome:R-HSA-429613 "SLC5As, NAGLT1 cotransport Glc and Na+ from extracellular region to cytosol";   reactome:R-HSA-8932955 "SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol"


show annotations for term's descendants           Sort by:
D-glucose:sodium symporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC5A1 solute carrier family 5 member 1 enables ISO
IBA
IDA
TAS		 (PMID:20980548), (PMID:34880492), (PMID:35077764), (PMID:8563765), (PMID:8836035) RGD
GO_Central
UniProt
Reactome		 PMID:8563765 PMID:8836035 PMID:15829715 PMID:20980548 PMID:34880492 More... GO_REF:0000033 RGD:1624261 Reactome:R-HSA-5656356 Reactome:R-HSA-8932955 NCBI chr22:32,043,261...32,113,029
Ensembl chr22:32,043,261...32,113,029 		JBrowse link
G SLC5A10 solute carrier family 5 member 10 enables IBA GO_Central GO_REF:0000033 NCBI chr17:18,950,676...19,022,565
Ensembl chr17:18,950,345...19,022,595 		JBrowse link
G SLC5A11 solute carrier family 5 member 11 enables IBA GO_Central GO_REF:0000033 NCBI chr16:24,845,963...24,911,626
Ensembl chr16:24,845,841...24,911,628 		JBrowse link
G SLC5A2 solute carrier family 5 member 2 enables ISO
IBA
IDA
EXP
TAS		 (PMID:20980548), (PMID:28592437)
(PMID:11133510)		 RGD
GO_Central
ARUK-UCL
Reactome		 PMID:7493971 PMID:11133510 PMID:14506074 PMID:20980548 PMID:28592437 GO_REF:0000033 RGD:1599050 RGD:633997 Reactome:R-HSA-429613 Reactome:R-HSA-5658163 NCBI chr16:31,483,123...31,490,769
Ensembl chr16:31,483,002...31,490,860 		JBrowse link
G SLC5A3 solute carrier family 5 member 3 enables ISS
IBA
IEA		 ARUK-UCL
GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 NCBI chr21:34,073,578...34,106,260
Ensembl chr21:34,073,578...34,106,260 		JBrowse link
G SLC5A4 solute carrier family 5 member 4 NOT|enables IDA
ISO		 (PMID:13130073), (PMID:20421923), (PMID:22766068)
(PMID:20392930)
(PMID:8077195)		 UniProt
UniProt		 PMID:8077195 PMID:13130073 PMID:20392930 PMID:20421923 PMID:22766068 NCBI chr22:32,218,464...32,355,063
Ensembl chr22:32,218,464...32,255,347 		JBrowse link
G SLC5A9 solute carrier family 5 member 9 enables IBA GO_Central GO_REF:0000033 NCBI chr 1:48,222,716...48,248,638
Ensembl chr 1:48,222,685...48,248,644 		JBrowse link
low-affinity D-glucose:sodium symporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC5A2 solute carrier family 5 member 2 enables TAS (PMID:8244402) PINC PMID:8244402 NCBI chr16:31,483,123...31,490,769
Ensembl chr16:31,483,002...31,490,860 		JBrowse link
G SLC5A4 solute carrier family 5 member 4 enables ISO (PMID:13130073) UniProt PMID:13130073 NCBI chr22:32,218,464...32,355,063
Ensembl chr22:32,218,464...32,255,347 		JBrowse link
G SLC5A9 solute carrier family 5 member 9 enables TAS Reactome Reactome:R-HSA-429567 NCBI chr 1:48,222,716...48,248,638
Ensembl chr 1:48,222,685...48,248,644 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 19551
    transporter activity 1302
      transmembrane transporter activity 1183
        carbohydrate transmembrane transporter activity 42
          carbohydrate:monoatomic cation symporter activity 16
            D-glucose:sodium symporter activity 7
              low-affinity D-glucose:sodium symporter activity 3
Path 2
Term Annotations click to browse term
  molecular_function 19551
    transporter activity 1302
      transmembrane transporter activity 1183
        monoatomic ion transmembrane transporter activity 799
          monoatomic cation transmembrane transporter activity 677
            metal ion transmembrane transporter activity 469
              sodium ion transmembrane transporter activity 169
                solute:sodium symporter activity 81
                  D-glucose:sodium symporter activity 7
                    low-affinity D-glucose:sodium symporter activity 3
paths to the root