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ONTOLOGY REPORT - ANNOTATIONS

Term:death receptor activity
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Accession:GO:0005035 term browser browse the term
Definition:Combining with an extracellular messenger (called a death ligand), and transmitting the signal from one side of the plasma membrane to the other to initiate apoptotic or necrotic cell death.
Synonyms:related_synonym: apoptosis-activating receptor activity

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death receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC101711815 death domain-containing membrane protein NRADD enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624730:74,280,616...74,283,789 JBrowse link
G Ngfr nerve growth factor receptor enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624795:5,623,686...5,639,545
Ensembl chrNW_004624795:5,623,700...5,639,655 		JBrowse link
TRAIL receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfrsf10b TNF receptor superfamily member 10b enables ISO (PMID:28362429) ARUK-UCL PMID:28362429 NCBI chrNW_004624758:18,464,005...18,498,740 JBrowse link
tumor necrosis factor receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eda2r ectodysplasin A2 receptor enables IEA InterPro GO_REF:0000002 NCBI chrNW_004624898:643,941...679,421
Ensembl chrNW_004624898:657,924...676,365 		JBrowse link
G Fas Fas cell surface death receptor enables ISO
IEA		 RGD
TreeGrafter		 PMID:16154149 GO_REF:0000118 RGD:1582433 NCBI chrNW_004624791:15,290,022...15,315,848
Ensembl chrNW_004624791:15,289,348...15,315,848 		JBrowse link
G Tnfrsf11a TNF receptor superfamily member 11a enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624792:8,029,383...8,087,824
Ensembl chrNW_004624792:8,029,364...8,084,424 		JBrowse link
G Tnfrsf18 TNF receptor superfamily member 18 enables IEA InterPro GO_REF:0000002 NCBI chrNW_004624818:8,376,204...8,380,266
Ensembl chrNW_004624818:8,378,131...8,379,974 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A enables ISO
IEA		 RGD
TreeGrafter
InterPro		 PMID:20649583 GO_REF:0000002 GO_REF:0000118 RGD:5130976 NCBI chrNW_004624860:3,111,244...3,123,041
Ensembl chrNW_004624860:3,111,630...3,122,711 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B enables IEA
ISO		 TreeGrafter
InterPro
RGD		 PMID:12376316 GO_REF:0000002 GO_REF:0000118 RGD:628388 NCBI chrNW_004624818:894,470...922,806
Ensembl chrNW_004624818:896,150...922,710 		JBrowse link
G Tnfrsf4 TNF receptor superfamily member 4 enables IEA TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004624818:8,372,092...8,376,108
Ensembl chrNW_004624818:8,373,810...8,376,204 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 18442
    molecular transducer activity 1985
      signaling receptor activity 1985
        transmembrane signaling receptor activity 1804
          death receptor activity 10
            TRAIL receptor activity 1
            tumor necrosis factor receptor activity 7
paths to the root