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ONTOLOGY REPORT - ANNOTATIONS

Term:granuloma formation
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Accession:GO:0002432 term browser browse the term
Definition:The formation of nodular inflammatory lesions, usually small or granular, firm, persistent, well-structured, and containing compactly grouped T lymphocytes and modified phagocytes such as epithelioid cells, giant cells, and other macrophages. Granuloma formation represents a chronic inflammatory response initiated by various infectious and noninfectious agents. The center of a granuloma consists of fused macrophages, which can become necrotic.

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granuloma formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CEBPB CCAAT enhancer binding protein beta involved_in ISO (MGI:4360613|PMID:17911624) UniProt PMID:17911624 MGI:4360613 NCBI chr 2:13,780,538...13,782,639
Ensembl chr 2:13,781,160...13,782,194 		JBrowse link
G UNC13D unc-13 homolog D acts_upstream_of_or_within ISO (PMID:17420270) MGI PMID:17420270 NCBI chr16:45,836,659...45,856,805
Ensembl chr16:45,838,175...45,857,201 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16925
    immune system process 2492
      immune effector process 667
        granuloma formation 2
          negative regulation of granuloma formation 0
          positive regulation of granuloma formation 0
          regulation of granuloma formation + 0
Path 2
Term Annotations click to browse term
  biological_process 16925
    response to stimulus 8685
      response to stress 3993
        defense response 1691
          inflammatory response 788
            chronic inflammatory response 31
              granuloma formation 2
                negative regulation of granuloma formation 0
                positive regulation of granuloma formation 0
                regulation of granuloma formation + 0
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