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ONTOLOGY REPORT - ANNOTATIONS

Term:transitional stage B cell differentiation
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Accession:GO:0002332 term browser browse the term
Definition:The process in which immature B cells from the bone marrow become mature B cells in the spleen. Transitional stage B cells are subdivided into transitional one (T1) and transitional two (T2) stages and are short-lived and functionally incompetent.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: transitional stage B-lymphocyte differentiation
 related_synonym: transitional stage B cell development


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transitional one stage B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:2153718 (PMID:19228876) RGD PMID:19228876 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065 		JBrowse link
G Tnfsf13b TNF superfamily member 13b acts_upstream_of_or_within ISO (PMID:17581616) RGD PMID:17581616 NCBI chr16:79,462,406...79,492,888
Ensembl chr16:79,462,402...79,492,693 		JBrowse link
transitional two stage B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Traf3ip2 Traf3 interacting protein 2 involved_in ISO MGI:3510784 (PMID:20543113) RGD PMID:20543113 NCBI chr20:43,011,405...43,054,654
Ensembl chr20:43,011,450...43,054,667 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20069
    immune system process 3008
      leukocyte activation 1056
        lymphocyte activation 856
          lymphocyte differentiation 444
            B cell differentiation 154
              immature B cell differentiation 24
                transitional stage B cell differentiation 3
                  transitional one stage B cell differentiation 2
                  transitional two stage B cell differentiation 1
Path 2
Term Annotations click to browse term
  biological_process 20069
    developmental process 7067
      cellular developmental process 4781
        cell differentiation 4780
          cell development 3325
            hemopoiesis 1075
              leukocyte differentiation 681
                mononuclear cell differentiation 546
                  lymphocyte differentiation 444
                    B cell differentiation 154
                      immature B cell differentiation 24
                        transitional stage B cell differentiation 3
                          transitional one stage B cell differentiation 2
                          transitional two stage B cell differentiation 1
paths to the root