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ONTOLOGY REPORT - ANNOTATIONS


Term:immature B cell differentiation
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Accession:GO:0002327 term browser browse the term
Definition:The process in which a precursor cell type acquires the specialized features of an immature B cell.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: immature B lymphocyte differentiation
 related_synonym: immature B cell development



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immature B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fnip1 folliculin interacting protein 1 acts_upstream_of_or_within
involved_in
ISO
ISS
MGI:5437714 (MGI:5436190|PMID:22608497)
GO_REF:0000024
RGD
UniProt
PMID:22608497 GO_REF:0000024 MGI:5436190 NCBI chr10:38,567,728...38,650,824
Ensembl chr10:38,567,729...38,650,824
JBrowse link
G Irf2bp2 interferon regulatory factor 2 binding protein 2 involved_in ISO (PMID:27016798) RGD PMID:27016798 NCBI chr19:54,559,409...54,564,714
Ensembl chr19:54,560,128...54,566,642
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase involved_in ISO (MGI:3040777|PMID:15067126) RGD PMID:15067126 MGI:3040777 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
JBrowse link
G Spi1 Spi-1 proto-oncogene involved_in ISO UniProtKB:O35906 (MGI:5926569|PMID:28062693) RGD PMID:28062693 MGI:5926569 NCBI chr 3:77,059,744...77,093,730
Ensembl chr 3:77,073,012...77,092,393
JBrowse link
G Spib Spi-B transcription factor involved_in ISO UniProtKB:P17433 (MGI:5926569|PMID:28062693) RGD PMID:28062693 MGI:5926569 NCBI chr 1:95,018,939...95,024,804
Ensembl chr 1:95,018,947...95,024,780
JBrowse link
G Syvn1 synoviolin 1 involved_in ISO (MGI:6220623|PMID:29907570) RGD PMID:29907570 MGI:6220623 NCBI chr 1:203,339,235...203,346,137
Ensembl chr 1:203,339,619...203,346,152
JBrowse link
negative regulation of pre-B cell receptor expression term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (MGI:5444793|PMID:22949502) RGD PMID:22949502 MGI:5444793 NCBI chr 5:143,087,759...143,109,807
Ensembl chr 5:143,087,759...143,109,807
JBrowse link
pre-B cell allelic exclusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ATM serine/threonine kinase involved_in ISO (MGI:3848557|PMID:19448632) RGD PMID:19448632 MGI:3848557 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Rag1 recombination activating 1 involved_in IBA
ISO
PMID:21873635
(MGI:3848557|PMID:19448632)
RGD PMID:19448632 PMID:21873635 MGI:3848557, RGD:13792537 NCBI chr 3:87,917,061...87,928,158
Ensembl chr 3:87,917,004...87,928,291
JBrowse link
G Rag2 recombination activating 2 involved_in ISO (MGI:3848557|PMID:19448632) RGD PMID:19448632 MGI:3848557 NCBI chr 3:87,902,373...87,910,227
Ensembl chr 3:87,902,238...87,911,066
JBrowse link
pre-B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp11c ATPase phospholipid transporting 11C involved_in ISO (MGI:5002406|PMID:21423173) RGD PMID:21423173 MGI:5002406 NCBI chr  X:138,564,459...138,752,116
Ensembl chr  X:138,565,836...138,751,204
JBrowse link
G Cd24 CD24 molecule acts_upstream_of_or_within ISO MGI:2179996 (MGI:2179980|PMID:9028339), (MGI:74794|PMID:7795661) RGD PMID:7795661 PMID:9028339 MGI:2179980 MGI:74794 NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662
JBrowse link
G Foxp1 forkhead box P1 acts_upstream_of_or_within ISO MGI:3711150 (MGI:3662963|PMID:16819554) RGD PMID:16819554 MGI:3662963 NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258
JBrowse link
G Lrrc8a leucine rich repeat containing 8 VRAC subunit A involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 3:13,509,577...13,537,174
Ensembl chr 3:13,510,513...13,536,202
JBrowse link
G Mir17 microRNA 17 acts_upstream_of_or_within ISO MGI:2676844|MGI:2676872|MGI:3618743|MGI:3629917|MGI:3629918 (MGI:3789916|PMID:18329372) RGD PMID:18329372 MGI:3789916 NCBI chr15:92,180,629...92,180,712
Ensembl chr15:92,180,629...92,180,712
JBrowse link
G Mir18a microRNA 18a acts_upstream_of_or_within ISO MGI:2676872|MGI:3618743|MGI:3619065|MGI:3629917|MGI:3629918 (MGI:3789916|PMID:18329372) RGD PMID:18329372 MGI:3789916 NCBI chr15:92,180,765...92,180,860
Ensembl chr15:92,180,765...92,180,860
JBrowse link
G Mir19a microRNA 19a acts_upstream_of_or_within ISO MGI:2676844|MGI:2676872|MGI:3619065|MGI:3629917|MGI:3629918 (MGI:3789916|PMID:18329372) RGD PMID:18329372 MGI:3789916 NCBI chr15:92,180,912...92,180,993
Ensembl chr15:92,180,912...92,180,993
JBrowse link
G Mir19b1 microRNA 19b-1 acts_upstream_of_or_within ISO MGI:2676844|MGI:2676872|MGI:3618743|MGI:3619065|MGI:3629918 (MGI:3789916|PMID:18329372) RGD PMID:18329372 MGI:3789916 NCBI chr15:92,181,214...92,181,300
Ensembl chr15:92,181,214...92,181,300
JBrowse link
G Mir20a microRNA 20a acts_upstream_of_or_within ISO MGI:2676844|MGI:3618743|MGI:3619065|MGI:3629917|MGI:3629918 (MGI:3789916|PMID:18329372) RGD PMID:18329372 MGI:3789916 NCBI chr15:92,181,084...92,181,168
Ensembl chr15:92,181,084...92,181,168
JBrowse link
G Mir92a1 microRNA 92a-1 acts_upstream_of_or_within ISO MGI:2676844|MGI:2676872|MGI:3618743|MGI:3619065|MGI:3629917 (MGI:3789916|PMID:18329372) RGD PMID:18329372 MGI:3789916 NCBI chr15:92,181,336...92,181,413
Ensembl chr15:92,181,336...92,181,413
JBrowse link
transitional one stage B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:2153718 (MGI:3839222|PMID:19228876) RGD PMID:19228876 MGI:3839222 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065
JBrowse link
transitional two stage B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Traf3ip2 Traf3 interacting protein 2 involved_in ISO MGI:3510784 (MGI:4460017|PMID:20543113) RGD PMID:20543113 MGI:4460017 NCBI chr20:43,011,405...43,054,654
Ensembl chr20:43,011,450...43,054,667
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19512
    immune system process 2869
      leukocyte activation 1078
        lymphocyte activation 893
          lymphocyte differentiation 427
            B cell differentiation 158
              immature B cell differentiation 22
                pre-B cell differentiation + 14
                transitional stage B cell differentiation + 2
Path 2
Term Annotations click to browse term
  biological_process 19512
    developmental process 6931
      anatomical structure development 6346
        multicellular organism development 5773
          system development 5413
            animal organ development 4174
              hematopoietic or lymphoid organ development 1046
                hemopoiesis 994
                  leukocyte differentiation 621
                    mononuclear cell differentiation 480
                      lymphocyte differentiation 427
                        B cell differentiation 158
                          immature B cell differentiation 22
                            pre-B cell differentiation + 14
                            transitional stage B cell differentiation + 2
paths to the root