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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of T cell mediated cytotoxicity
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Accession:GO:0001916 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of T cell mediated cytotoxicity.
Synonyms:exact_synonym: positive regulation of T cell mediated apoptosis;   positive regulation of T-cell mediated cell death;   positive regulation of T-cell mediated cell killing;   positive regulation of T-lymphocyte mediated cytotoxicity;   up regulation of T cell mediated cytotoxicity;   upregulation of T cell mediated cytotoxicity
 narrow_synonym: activation of T cell mediated cytotoxicity;   stimulation of T cell mediated cytotoxicity
 related_synonym: positive regulation of T-cell mediated cytolysis

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positive regulation of T cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B2m beta-2-microglobulin acts_upstream_of_or_within ISO (PMID:16299293) MGI PMID:16299293 NCBI chrNW_004624804:11,514,728...11,521,625 JBrowse link
G Cyrib CYFIP related Rac1 interactor B involved_in ISO (MGI:5432330|PMID:22522492) UniProt PMID:22522492 MGI:5432330 NCBI chrNW_004624735:25,752,675...25,894,193
Ensembl chrNW_004624735:25,820,175...25,894,193 		JBrowse link
G Fadd Fas associated via death domain involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chrNW_004624767:17,050,929...17,059,648
Ensembl chrNW_004624767:17,055,509...17,059,705 		JBrowse link
G Hfe homeostatic iron regulator involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624756:821,738...831,482
Ensembl chrNW_004624756:823,947...831,376 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 ISO RGD PMID:8871636 RGD:10059395 NCBI chrNW_004624880:2,070,410...2,075,069
Ensembl chrNW_004624880:2,070,523...2,079,421 		JBrowse link
G Il12a interleukin 12A involved_in ISO (PMID:1674604), (PMID:2204066) UniProt PMID:1674604 PMID:2204066 NCBI chrNW_004624730:37,787,772...37,794,871
Ensembl chrNW_004624730:37,787,909...37,794,940 		JBrowse link
G Il12b interleukin 12B involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624733:30,146,050...30,156,144
Ensembl chrNW_004624733:30,146,050...30,154,589 		JBrowse link
G Il23a interleukin 23 subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624802:11,662,851...11,664,444
Ensembl chrNW_004624802:11,662,753...11,665,418 		JBrowse link
G LOC101697206 T-cell surface glycoprotein CD1c3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624805:5,853,594...5,856,018 JBrowse link
G LOC101700189 major histocompatibility complex class I-related gene protein involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624771:1,275,364...1,298,967
Ensembl chrNW_004624771:1,275,302...1,293,552 		JBrowse link
G LOC101706353 HLA class II histocompatibility antigen, DR alpha chain involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624754:24,079,459...24,086,342
Ensembl chrNW_004624754:24,079,366...24,084,512 		JBrowse link
G LOC101721592 class I histocompatibility antigen, Gogo-B*0102 alpha chain-like involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624754:24,680,008...24,683,547
Ensembl chrNW_004624754:24,680,085...24,683,925 		JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO (PMID:14761980) MGI PMID:14761980 NCBI chrNW_004624747:21,725,813...21,768,123
Ensembl chrNW_004624747:21,725,395...21,759,453 		JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C acts_upstream_of_or_within ISO (PMID:6233370) MGI PMID:6233370 NCBI chrNW_004624798:1,700,732...1,814,603
Ensembl chrNW_004624798:1,699,541...1,814,656 		JBrowse link
G Stx7 syntaxin 7 involved_in ISO (PMID:21438968) UniProt PMID:21438968 NCBI chrNW_004624753:6,511,516...6,554,406
Ensembl chrNW_004624753:6,514,056...6,547,480 		JBrowse link
G Tap2 transporter 2, ATP binding cassette subfamily B member acts_upstream_of_or_within ISO PMID:1758495
(PMID:1538753)
(PMID:16299293)		 MGI PMID:1538753 PMID:1758495 PMID:16299293 RGD:1299069 NCBI chrNW_004624754:23,827,782...23,845,690
Ensembl chrNW_004624754:23,827,706...23,837,356 		JBrowse link
positive regulation of T cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC101700189 major histocompatibility complex class I-related gene protein involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624771:1,275,364...1,298,967
Ensembl chrNW_004624771:1,275,302...1,293,552 		JBrowse link
G Slc22a13 solute carrier family 22 member 13 involved_in ISO (PMID:19282870) UniProt PMID:19282870 NCBI chrNW_004624773:19,950,353...19,968,029
Ensembl chrNW_004624773:19,950,303...19,962,575 		JBrowse link
susceptibility to T cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC101712173 poliovirus receptor homolog involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624907:1,582,636...1,596,528 JBrowse link
G Nectin2 nectin cell adhesion molecule 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624907:1,713,786...1,739,158
Ensembl chrNW_004624907:1,713,443...1,740,627 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15093
    cellular process 14237
      cell killing 141
        leukocyte mediated cytotoxicity 98
          positive regulation of leukocyte mediated cytotoxicity 40
            positive regulation of T cell mediated cytotoxicity 19
              positive regulation of T cell mediated cytotoxicity directed against tumor cell target 2
              positive regulation of cytotoxic T cell degranulation 0
              susceptibility to T cell mediated cytotoxicity 2
Path 2
Term Annotations click to browse term
  biological_process 15093
    biological regulation 10618
      regulation of biological process 10301
        regulation of immune system process 1351
          regulation of immune effector process 357
            regulation of leukocyte mediated immunity 220
              regulation of lymphocyte mediated immunity 153
                regulation of T cell mediated immunity 76
                  regulation of T cell mediated cytotoxicity 25
                    positive regulation of T cell mediated cytotoxicity 19
                      positive regulation of T cell mediated cytotoxicity directed against tumor cell target 2
                      positive regulation of cytotoxic T cell degranulation 0
                      susceptibility to T cell mediated cytotoxicity 2
paths to the root