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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of leukocyte mediated cytotoxicity
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Accession:GO:0001912 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of leukocyte mediated cytotoxicity.
Synonyms:exact_synonym: positive regulation of immune cell mediated cytotoxicity;   positive regulation of leucocyte mediated cytotoxicity;   up regulation of leukocyte mediated cytotoxicity;   upregulation of leukocyte mediated cytotoxicity
 narrow_synonym: activation of leukocyte mediated cytotoxicity;   stimulation of leukocyte mediated cytotoxicity


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positive regulation of leukocyte mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl2 C-C motif chemokine ligand 2 IMP RGD PMID:8103296 RGD:8549560 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
positive regulation of antibody-dependent cellular cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RT1-A2 RT1 class Ia, locus A2 involved_in ISO (PMID:30134159) RGD PMID:30134159 NCBI chr20:4,870,939...4,910,183 JBrowse link
positive regulation of microglial cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itgam integrin subunit alpha M involved_in ISO (PMID:18685038) RGD PMID:18685038 NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503 		JBrowse link
G Spi1 Spi-1 proto-oncogene involved_in ISO (PMID:28628103) RGD PMID:28628103 NCBI chr 3:77,059,744...77,093,730
Ensembl chr 3:77,073,012...77,092,393 		JBrowse link
G Stap1 signal transducing adaptor family member 1 involved_in ISO (PMID:19100238) RGD PMID:19100238 NCBI chr14:21,950,466...21,981,395
Ensembl chr14:21,952,496...21,981,245 		JBrowse link
G Tyrobp transmembrane immune signaling adaptor Tyrobp involved_in IBA
ISO		 GO_REF:0000033
(PMID:18685038)		 GO_Central
RGD		 PMID:18685038 GO_REF:0000033 NCBI chr 1:85,672,931...85,676,856
Ensembl chr 1:85,672,994...85,676,848 		JBrowse link
positive regulation of natural killer cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap1g1 adaptor related protein complex 1 subunit gamma 1 involved_in ISO (PMID:23632890) RGD PMID:23632890 NCBI chr19:37,744,633...37,831,134
Ensembl chr19:37,744,633...37,829,167 		JBrowse link
G Cd160 CD160 molecule involved_in ISO (PMID:19109136) RGD PMID:19109136 NCBI chr 2:184,340,820...184,383,421
Ensembl chr 2:184,340,599...184,375,834 		JBrowse link
G Klrc2 killer cell lectin like receptor C2 involved_in ISO (PMID:21825173) RGD PMID:21825173 NCBI chr 4:163,122,700...163,133,843
Ensembl chr 4:163,122,704...163,133,843 		JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 involved_in ISO
IEA		 (PMID:23632890)
GO_REF:0000107		 RGD
Ensembl		 PMID:23632890 GO_REF:0000107 NCBI chr16:76,355,982...76,380,700
Ensembl chr16:76,355,984...76,381,883 		JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO (PMID:27455421) RGD PMID:27455421 NCBI chr20:3,403,418...3,479,476 JBrowse link
positive regulation of natural killer cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap1g1 adaptor related protein complex 1 subunit gamma 1 involved_in ISO (PMID:23632890) RGD PMID:23632890 NCBI chr19:37,744,633...37,831,134
Ensembl chr19:37,744,633...37,829,167 		JBrowse link
G Bid BH3 interacting domain death agonist IMP RGD PMID:17893612 RGD:408346749 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720 		JBrowse link
G Cadm1 cell adhesion molecule 1 involved_in ISO
ISS		 (PMID:15811952)
GO_REF:0000024		 RGD
HGNC		 PMID:15811952 GO_REF:0000024 NCBI chr 8:47,847,836...48,178,703
Ensembl chr 8:47,847,325...48,182,833 		JBrowse link
G Cd160 CD160 molecule involved_in ISO (PMID:12486241), (PMID:17307798) RGD PMID:12486241 PMID:17307798 NCBI chr 2:184,340,820...184,383,421
Ensembl chr 2:184,340,599...184,375,834 		JBrowse link
G Cd226 CD226 molecule involved_in ISO (PMID:16304049) RGD PMID:16304049 NCBI chr18:82,449,924...82,545,107
Ensembl chr18:82,450,568...82,543,051 		JBrowse link
G Crtam cytotoxic and regulatory T cell molecule involved_in ISO (PMID:15811952) RGD PMID:15811952 NCBI chr 8:41,340,117...41,377,381
Ensembl chr 8:41,340,837...41,377,343 		JBrowse link
G Gimap5 GTPase, IMAP family member 5 IMP RGD PMID:15100275 RGD:2303778 NCBI chr 4:77,693,417...77,701,025
Ensembl chr 4:77,687,564...77,703,086 		JBrowse link
G Il12a interleukin 12A involved_in ISO (PMID:2204066) RGD PMID:2204066 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734 		JBrowse link
G Il18rap interleukin 18 receptor accessory protein acts_upstream_of_or_within ISO MGI:3579137 (PMID:15843532) RGD PMID:15843532 NCBI chr 9:42,768,112...42,800,964
Ensembl chr 9:42,768,220...42,800,959 		JBrowse link
G Il21 interleukin 21 involved_in
acts_upstream_of_or_within		 ISO
IBA
IEA		 (PMID:18005035)
GO_REF:0000033
(PMID:14764669)
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:14764669 PMID:18005035 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:120,117,105...120,127,012
Ensembl chr 2:120,119,444...120,126,996 		JBrowse link
G Klrc1 killer cell lectin like receptor C1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:163,142,142...163,152,425
Ensembl chr 4:163,147,189...163,152,425 		JBrowse link
G Klrc2 killer cell lectin like receptor C2 involved_in ISO (PMID:9754572) RGD PMID:9754572 NCBI chr 4:163,122,700...163,133,843
Ensembl chr 4:163,122,704...163,133,843 		JBrowse link
G Klrd1 killer cell lectin like receptor D1 involved_in ISO
IBA
IEA		 (PMID:9754572)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:9754572 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:163,044,920...163,056,568
Ensembl chr 4:163,045,067...163,056,518 		JBrowse link
G Klre1 killer cell lectin like receptor E1 involved_in ISO
IBA		 (PMID:15294961)
GO_REF:0000033		 RGD
GO_Central		 PMID:15294961 GO_REF:0000033 NCBI chr 4:163,033,581...163,041,641
Ensembl chr 4:163,033,563...163,041,638 		JBrowse link
G Klrh1 killer cell lectin-like receptor subfamily H, member 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:163,288,228...163,301,977
Ensembl chr 4:163,288,229...163,300,535 		JBrowse link
G Klri1 killer cell lectin-like receptor family I member 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:163,183,675...163,218,903
Ensembl chr 4:163,183,669...163,218,870 		JBrowse link
G Klri2 killer cell lectin-like receptor family I member 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:163,252,844...163,261,484
Ensembl chr 4:163,252,844...163,261,484 		JBrowse link
G Klrk1 killer cell lectin like receptor K1 involved_in
acts_upstream_of_or_within		 ISS
ISO
IBA
IEA		 GO_REF:0000024
(PMID:15294961)
(PMID:12645935)
GO_REF:0000033
GO_REF:0000002
GO_REF:0000107		 UniProt
RGD
GO_Central
InterPro
Ensembl		 PMID:12645935 PMID:15294961 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:163,079,887...163,092,434
Ensembl chr 4:163,081,927...163,092,459 		JBrowse link
G Lag3 lymphocyte activating 3 acts_upstream_of_or_within ISO MGI:2176269 (PMID:8602528) RGD PMID:8602528 NCBI chr 4:157,712,665...157,722,229
Ensembl chr 4:157,712,667...157,720,404 		JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 involved_in ISO (PMID:23632890) RGD PMID:23632890 NCBI chr16:76,355,982...76,380,700
Ensembl chr16:76,355,984...76,381,883 		JBrowse link
G Ly49s3 Ly-49 stimulatory receptor 3 IDA RGD PMID:12077224 RGD:633264 Ensembl chr 4:164,122,072...164,341,692 JBrowse link
G Ncr3 natural cytotoxicity triggering receptor 3 involved_in ISO
IBA
IEA		 (PMID:16304049)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000002		 RGD
GO_Central
Ensembl
InterPro		 PMID:16304049 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr20:3,637,242...3,643,748
Ensembl chr20:3,638,240...3,643,799 		JBrowse link
G Nectin2 nectin cell adhesion molecule 2 involved_in ISO (PMID:16304049) RGD PMID:16304049 NCBI chr 1:79,372,123...79,407,379
Ensembl chr 1:79,372,119...79,407,360 		JBrowse link
G Pvr PVR cell adhesion molecule involved_in ISO (PMID:16304049) RGD PMID:16304049 NCBI chr 1:79,561,294...79,576,700
Ensembl chr 1:79,546,879...79,576,715 		JBrowse link
G Raet1e retinoic acid early transcript 1E involved_in ISO (PMID:18544572) RGD PMID:18544572 NCBI chr 1:1,662,665...1,664,609
Ensembl chr 1:1,807,644...1,812,755 		JBrowse link
G Raet1l retinoic acid early transcript 1L IDA RGD PMID:20306467 RGD:9685184 NCBI chr 1:1,979,433...1,984,410
Ensembl chr 1:1,979,443...1,984,410 		JBrowse link
G Raet1ll1 retinoic acid early transcript 1L like 1 IDA RGD PMID:20306467 RGD:9685184 NCBI chr 1:1,397,219...1,437,802
Ensembl chr 1:1,397,230...1,402,656 		JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 involved_in ISO
IEA		 (PMID:19933860)
GO_REF:0000107		 RGD
Ensembl		 PMID:19933860 GO_REF:0000107 NCBI chr 3:104,168,549...104,230,107
Ensembl chr 3:104,170,013...104,230,056 		JBrowse link
G RT1-A2 RT1 class Ia, locus A2 involved_in ISO (PMID:23335510) RGD PMID:23335510 NCBI chr20:4,870,939...4,910,183 JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 acts_upstream_of_or_within ISO MGI:3701255 (PMID:16476767) RGD PMID:16476767 NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117 		JBrowse link
G Sh2d1a SH2 domain containing 1A acts_upstream_of_or_within ISO MGI:1349420|MGI:3575311|MGI:3622649 (PMID:16127454), (PMID:19648922) RGD PMID:16127454 PMID:19648922 NCBI chr  X:121,373,693...121,401,923 JBrowse link
G Sh2d1b2 SH2 domain containing 1B2 acts_upstream_of_or_within ISO MGI:1328352|MGI:1349420|MGI:98923 (PMID:19648922), (PMID:20962259) RGD PMID:19648922 PMID:20962259 NCBI chr13:82,437,418...82,461,511
Ensembl chr13:82,437,428...82,461,509 		JBrowse link
G Slamf6 SLAM family member 6 involved_in ISO (PMID:16920955) RGD PMID:16920955 NCBI chr13:84,384,561...84,405,300
Ensembl chr13:84,383,742...84,405,300 		JBrowse link
G Stat5a signal transducer and activator of transcription 5A acts_upstream_of_or_within ISO MGI:1857249 (PMID:9841920) RGD PMID:9841920 NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866 		JBrowse link
G Stat5b signal transducer and activator of transcription 5B involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2181592 (PMID:9841920)		 Ensembl
RGD		 PMID:9841920 GO_REF:0000107 NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668 		JBrowse link
G Vav1 vav guanine nucleotide exchange factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1349420|MGI:3622649 (PMID:20962259)		 Ensembl
RGD		 PMID:20962259 GO_REF:0000107 NCBI chr 9:2,161,985...2,209,951
Ensembl chr 9:2,157,900...2,208,937 		JBrowse link
positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd226 CD226 molecule involved_in ISO (PMID:12913096) RGD PMID:12913096 NCBI chr18:82,449,924...82,545,107
Ensembl chr18:82,450,568...82,543,051 		JBrowse link
G Crtam cytotoxic and regulatory T cell molecule involved_in ISO
IBA		 (PMID:15811952)
GO_REF:0000033		 RGD
GO_Central		 PMID:15811952 GO_REF:0000033 NCBI chr 8:41,340,117...41,377,381
Ensembl chr 8:41,340,837...41,377,343 		JBrowse link
G Il12a interleukin 12A involved_in ISO
IEA		 (PMID:7903063)
GO_REF:0000107		 RGD
Ensembl		 PMID:7903063 GO_REF:0000107 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734 		JBrowse link
G Il12b interleukin 12B involved_in ISO (PMID:7903063) RGD PMID:7903063 NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903 		JBrowse link
G Klrk1 killer cell lectin like receptor K1 IMP RGD PMID:16323246 RGD:9685180 NCBI chr 4:163,079,887...163,092,434
Ensembl chr 4:163,081,927...163,092,459 		JBrowse link
G Nectin2 nectin cell adhesion molecule 2 involved_in ISO
IBA		 (PMID:12913096)
GO_REF:0000033		 RGD
GO_Central		 PMID:12913096 GO_REF:0000033 NCBI chr 1:79,372,123...79,407,379
Ensembl chr 1:79,372,119...79,407,360 		JBrowse link
G Pvr PVR cell adhesion molecule involved_in ISO (PMID:12913096) RGD PMID:12913096 NCBI chr 1:79,561,294...79,576,700
Ensembl chr 1:79,546,879...79,576,715 		JBrowse link
G Raet1ll1 retinoic acid early transcript 1L like 1 IMP RGD PMID:16323246 RGD:9685180 NCBI chr 1:1,397,219...1,437,802
Ensembl chr 1:1,397,230...1,402,656 		JBrowse link
positive regulation of neutrophil mediated killing of fungus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg1 arginase 1 involved_in ISO
IEA		 (PMID:15546957)
GO_REF:0000107		 RGD
Ensembl		 PMID:15546957 GO_REF:0000107 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:10725737)		 Ensembl
RGD		 PMID:10725737 GO_REF:0000107 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215 		JBrowse link
G Pomc proopiomelanocortin involved_in ISO (PMID:10670585) RGD PMID:10670585 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664 		JBrowse link
positive regulation of neutrophil mediated killing of gram-negative bacterium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2rl1 F2R like trypsin receptor 1 involved_in ISO (PMID:21501162) RGD PMID:21501162 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226 		JBrowse link
positive regulation of T cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07000147.1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033
G AABR07001348.1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr 1:39,668,472...39,670,153 JBrowse link
G AABR07044308.1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr20:1,789,779...1,793,115 JBrowse link
G AABR07044308.2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr20:1,768,641...1,772,357 JBrowse link
G AABR07044362.1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr20:2,630,622...2,634,751 JBrowse link
G AABR07044383.1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr20:3,403,777...3,436,874 JBrowse link
G Azgp1 alpha-2-glycoprotein 1, zinc-binding involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:16,930,990...16,939,333
Ensembl chr12:16,931,024...16,939,091 		JBrowse link
G B2m beta-2 microglobulin acts_upstream_of_or_within ISO (PMID:16299293) RGD PMID:16299293 NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766 		JBrowse link
G Cd1d1 CD1d1 molecule involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:10201995)		 GO_Central
RGD		 PMID:10201995 GO_REF:0000033 NCBI chr 2:172,423,582...172,427,089
Ensembl chr 2:172,423,582...172,427,089 		JBrowse link
G Cyrib CYFIP related Rac1 interactor B involved_in ISO (PMID:22522492) RGD PMID:22522492 NCBI chr 7:95,633,876...95,760,588
Ensembl chr 7:95,633,876...95,697,686 		JBrowse link
G ENSRNOG00000064836 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr20:2,606,621...2,618,153 JBrowse link
G ENSRNOG00000069480 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr20:3,310,825...3,421,372 JBrowse link
G ENSRNOG00000070971 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr 1:1,841,026...1,859,446 JBrowse link
G Fadd Fas associated via death domain involved_in ISS
ISO		 GO_REF:0000024
(PMID:21876153)		 UniProt
RGD		 PMID:21876153 GO_REF:0000024 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653 		JBrowse link
G H2-M10.6l histocompatibility 2, M region locus 10.6 like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:1,958,270...1,965,247
Ensembl chr20:1,925,049...1,966,105 		JBrowse link
G H60al histocompatibility 60a like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:1,382,896...1,386,846
Ensembl chr 1:1,588,152...1,590,424 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B IDA prevention of heat shock-induced resistance to CTL-mediated killing RGD PMID:10679071 RGD:1298959 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 IMP RGD PMID:8871636 RGD:10059395 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259 		JBrowse link
G Il12a interleukin 12A involved_in ISO
IEA		 (PMID:1674604), (PMID:2204066)
GO_REF:0000107		 RGD
Ensembl		 PMID:1674604 PMID:2204066 GO_REF:0000107 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734 		JBrowse link
G Il12b interleukin 12B involved_in ISO (PMID:14688363) RGD PMID:14688363 NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903 		JBrowse link
G Il23a interleukin 23 subunit alpha involved_in ISO (PMID:14688363) RGD PMID:14688363 NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923 		JBrowse link
G LOC120093164 retinoic acid early-inducible protein 1-gamma-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:1,807,226...1,812,755
Ensembl chr 1:1,807,644...1,812,755 		JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO MGI:3042190 (PMID:14761980) RGD PMID:14761980 NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619 		JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C acts_upstream_of_or_within ISO (PMID:6233370) RGD PMID:6233370 NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692 		JBrowse link
G Raet1l retinoic acid early transcript 1L involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:1,979,433...1,984,410
Ensembl chr 1:1,979,443...1,984,410 		JBrowse link
G Raet1ll1 retinoic acid early transcript 1L like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:1,397,219...1,437,802
Ensembl chr 1:1,397,230...1,402,656 		JBrowse link
G RT1-A RT1 class I, locus A involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033
G RT1-A1 RT1 class Ia, locus A1 IDA RGD PMID:11773898 RGD:2313503 NCBI chr20:4,905,309...4,914,593 JBrowse link
G RT1-A2 RT1 class Ia, locus A2 involved_in
acts_upstream_of_or_within		 ISO (PMID:20195504), (PMID:25631937)
(PMID:1538753)		 RGD PMID:1538753 PMID:20195504 PMID:25631937 NCBI chr20:4,870,939...4,910,183 JBrowse link
G RT1-CE1 RT1 class I, locus1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:3,555,779...3,559,487
Ensembl chr20:3,555,782...3,559,486 		JBrowse link
G RT1-CE10 RT1 class I, locus CE10 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:3,377,284...3,380,301 JBrowse link
G RT1-CE11 RT1 class I, locus CE11 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:3,355,393...3,358,520
Ensembl chr20:3,350,937...3,380,362 		JBrowse link
G RT1-CE12 RT1 class I, locus CE12 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:3,338,907...3,342,547 JBrowse link
G RT1-CE14 RT1 class I, locus CE14 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:3,296,654...3,300,795
Ensembl chr20:3,297,196...3,305,134 		JBrowse link
G RT1-CE16 RT1 class I, locus CE16 involved_in ISO
IBA		 (PMID:22031944), (PMID:2420472), (PMID:25631937), (PMID:8805302)
GO_REF:0000033		 RGD
GO_Central		 PMID:2420472 PMID:8805302 PMID:22031944 PMID:25631937 GO_REF:0000033 NCBI chr20:3,257,109...3,260,747
Ensembl chr20:3,257,123...3,279,563 		JBrowse link
G RT1-CE3 RT1 class I, locus CE3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:3,516,647...3,520,938
Ensembl chr20:2,623,953...2,692,081 		JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO (PMID:23851683) RGD PMID:23851683 NCBI chr20:3,403,418...3,479,476 JBrowse link
G RT1-Da RT1 class II, locus Da involved_in ISO (PMID:29884618) RGD PMID:29884618 NCBI chr20:4,513,464...4,518,457
Ensembl chr20:4,512,911...4,518,455 		JBrowse link
G RT1-Db1 RT1 class II, locus Db1 involved_in ISO (PMID:29884618) RGD PMID:29884618 NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258 		JBrowse link
G RT1-M1-2 RT1 class I, locus M1, gene 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:1,909,506...1,913,423
Ensembl chr20:1,910,656...1,917,936 		JBrowse link
G RT1-M1-4 RT1 class I, locus M1, gene 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:1,891,365...1,893,585
Ensembl chr20:1,889,164...1,893,815 		JBrowse link
G RT1-M1-5 RT1 class I, M1, gene 5 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:1,858,608...1,860,708
Ensembl chr20:1,811,604...1,860,708 		JBrowse link
G RT1-M10-1 RT1 class I, locus M10, gene 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:1,986,817...1,988,908
Ensembl chr20:1,986,788...2,020,117 		JBrowse link
G RT1-M2 RT1 class Ib, locus M2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:978,918...981,510
Ensembl chr20:978,935...981,723 		JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:3701255 (PMID:16299293), (PMID:16461341), (PMID:16476767), (PMID:8464890)
GO_REF:0000033		 RGD
GO_Central		 PMID:8464890 PMID:16299293 PMID:16461341 PMID:16476767 GO_REF:0000033 NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117 		JBrowse link
G RT1-M5 RT1 class Ib, locus M5 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:1,546,496...1,548,948
Ensembl chr20:1,546,511...1,548,775 		JBrowse link
G RT1-M6-2 RT1 class I, locus M6, gene 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:1,583,267...1,587,099
Ensembl chr20:1,583,299...1,586,215 		JBrowse link
G RT1-N1 RT1 class Ib, locus N1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033
G RT1-N2 RT1 class Ib, locus N2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:2,641,157...2,645,439
Ensembl chr20:2,641,202...2,644,900 		JBrowse link
G RT1-N3 RT1 class Ib, locus N3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:2,659,132...2,665,536
Ensembl chr20:2,661,584...2,665,530 		JBrowse link
G RT1-O1l1 RT1 class Ib, locus O1 like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:2,624,073...2,658,023
Ensembl chr20:2,623,953...2,692,081 		JBrowse link
G RT1-S3 RT1 class Ib, locus S3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:2,670,654...2,675,411
Ensembl chr20:2,670,709...2,675,411 		JBrowse link
G RT1-T24-1 RT1 class I, locus T24, gene 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:2,761,495...2,774,871
Ensembl chr20:2,718,279...2,776,154 		JBrowse link
G RT1-T24-3 RT1 class I, locus T24, gene 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:2,718,210...2,730,604
Ensembl chr20:2,718,279...2,776,154 		JBrowse link
G RT1-T24-4 RT1 class I, locus T24, gene 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:2,684,515...2,747,878
Ensembl chr20:2,684,515...2,692,511
Ensembl chr20:2,684,515...2,692,511 		JBrowse link
G Stx7 syntaxin 7 involved_in ISO
IEA		 (PMID:21438968)
GO_REF:0000107		 RGD
Ensembl		 PMID:21438968 GO_REF:0000107 NCBI chr 1:21,197,075...21,237,320
Ensembl chr 1:21,197,075...21,237,279 		JBrowse link
G Tap2 transporter 2, ATP binding cassette subfamily B member acts_upstream_of_or_within
involved_in		 IDA
ISO
IEA		 PMID:1758495
(PMID:1538753), (PMID:16299293)
GO_REF:0000107		 RGD
Ensembl		 PMID:1538753 PMID:16299293 PMID:1758495 GO_REF:0000107, RGD:1299069 NCBI chr20:4,636,347...4,650,387
Ensembl chr20:4,636,357...4,650,407 		JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (PMID:18832695) RGD PMID:18832695 NCBI chr13:77,248,687...77,252,343
Ensembl chr13:77,248,717...77,252,329 		JBrowse link
positive regulation of T cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mr1 major histocompatibility complex, class I-related involved_in ISO
IEA		 (PMID:31959982)
GO_REF:0000107		 RGD
Ensembl		 PMID:31959982 GO_REF:0000107 NCBI chr13:67,298,362...67,317,985
Ensembl chr13:67,299,585...67,317,970 		JBrowse link
G Slc22a13 solute carrier family 22 member 13 involved_in ISO (PMID:19282870) RGD PMID:19282870 NCBI chr 8:118,922,367...118,934,020
Ensembl chr 8:118,922,367...118,953,635 		JBrowse link
susceptibility to natural killer cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cadm1 cell adhesion molecule 1 involved_in ISS
ISO
IBA		 GO_REF:0000024
(PMID:15811952)
GO_REF:0000033		 HGNC
RGD
GO_Central		 PMID:15811952 GO_REF:0000024 GO_REF:0000033 NCBI chr 8:47,847,836...48,178,703
Ensembl chr 8:47,847,325...48,182,833 		JBrowse link
G Nectin2 nectin cell adhesion molecule 2 involved_in ISO (PMID:12913096) RGD PMID:12913096 NCBI chr 1:79,372,123...79,407,379
Ensembl chr 1:79,372,119...79,407,360 		JBrowse link
G Pvr PVR cell adhesion molecule involved_in ISO (PMID:12913096) RGD PMID:12913096 NCBI chr 1:79,561,294...79,576,700
Ensembl chr 1:79,546,879...79,576,715 		JBrowse link
G Ulbp1 UL16 binding protein 1 acts_upstream_of_or_within ISO (PMID:12645935) RGD PMID:12645935 NCBI chr 1:1,694,255...1,716,160 JBrowse link
susceptibility to T cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nectin2 nectin cell adhesion molecule 2 involved_in ISO (PMID:15039383) RGD PMID:15039383 NCBI chr 1:79,372,123...79,407,379
Ensembl chr 1:79,372,119...79,407,360 		JBrowse link
G Pvr PVR cell adhesion molecule involved_in ISO (PMID:15039383) RGD PMID:15039383 NCBI chr 1:79,561,294...79,576,700
Ensembl chr 1:79,546,879...79,576,715 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20535
    cellular process 19524
      cell killing 242
        positive regulation of cell killing 106
          positive regulation of leukocyte mediated cytotoxicity 101
            positive regulation of T cell mediated cytotoxicity + 62
            positive regulation of antibody-dependent cellular cytotoxicity 1
            positive regulation of microglial cell mediated cytotoxicity 4
            positive regulation of natural killer cell mediated cytotoxicity + 39
            positive regulation of neutrophil mediated cytotoxicity + 4
Path 2
Term Annotations click to browse term
  biological_process 20535
    biological regulation 13817
      regulation of biological process 13372
        regulation of immune system process 1732
          regulation of immune effector process 480
            regulation of leukocyte mediated immunity 316
              positive regulation of leukocyte mediated immunity 198
                positive regulation of leukocyte mediated cytotoxicity 101
                  positive regulation of T cell mediated cytotoxicity + 62
                  positive regulation of antibody-dependent cellular cytotoxicity 1
                  positive regulation of microglial cell mediated cytotoxicity 4
                  positive regulation of natural killer cell mediated cytotoxicity + 39
                  positive regulation of neutrophil mediated cytotoxicity + 4
paths to the root