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ONTOLOGY REPORT - ANNOTATIONS


Term:lactosylceramide biosynthetic process
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Accession:GO:0001572 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of lactosylceramides, Gal-beta-(1->4)-Glc-beta(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group. They are the precursors of both gangliosides and globosides.
Synonyms:exact_synonym: lactosylceramide anabolism;   lactosylceramide biosynthesis;   lactosylceramide formation;   lactosylceramide synthesis



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lactosylceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B4galt4 beta-1,4-galactosyltransferase 4 involved_in ISO
ISS
(PMID:9792633)
GO_REF:0000024
RGD
UniProt
PMID:9792633 GO_REF:0000024 NCBI chr11:61,995,807...62,021,751
Ensembl chr11:61,995,814...62,021,671
JBrowse link
G B4galt6 beta-1,4-galactosyltransferase 6 involved_in ISO (PMID:10320813) RGD PMID:10320813 NCBI chr18:11,958,382...12,015,247
Ensembl chr18:11,958,390...12,015,247
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20553
    cellular process 19543
      metabolic process 12181
        biosynthetic process 8678
          amide biosynthetic process 160
            ceramide biosynthetic process 74
              lactosylceramide biosynthetic process 2
Path 2
Term Annotations click to browse term
  biological_process 20553
    cellular process 19543
      metabolic process 12181
        primary metabolic process 10757
          lipid metabolic process 1464
            membrane lipid metabolic process 208
              glycolipid metabolic process 102
                glycosphingolipid metabolic process 60
                  glycosphingolipid biosynthetic process 32
                    lactosylceramide biosynthetic process 2
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