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ONTOLOGY REPORT - ANNOTATIONS


Term:ceramide biosynthetic process
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Accession:GO:0046513 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of ceramides, any N-acylated sphingoid.
Synonyms:exact_synonym: ceramide anabolism;   ceramide biosynthesis;   ceramide formation;   ceramide synthesis



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ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agk acylglycerol kinase involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:3054595|PMID:15252046)
RGD PMID:15252046 PMID:21873635 MGI:3054595, RGD:13792537 NCBI chr 4:69,114,850...69,193,989
Ensembl chr 4:69,114,269...69,193,934
JBrowse link
G Alox12b arachidonate 12-lipoxygenase, 12R type involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:3789553|PMID:17403930)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:17403930 GO_REF:0000024 GO_REF:0000107 MGI:3789553 NCBI chr10:53,863,060...53,874,938
Ensembl chr10:53,863,060...53,874,938
JBrowse link
G Aloxe3 arachidonate lipoxygenase 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:5488571|PMID:22832496)
UniProt
RGD
PMID:22832496 GO_REF:0000024 MGI:5488571 NCBI chr10:53,830,219...53,854,328
Ensembl chr10:53,831,264...53,854,328
JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 involved_in ISO
IEA
ISS
(PMID:12764132), (PMID:12815059)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:12764132 PMID:12815059 GO_REF:0000024 GO_REF:0000107 NCBI chr16:50,966,404...50,997,827
Ensembl chr16:50,966,229...51,008,233
JBrowse link
G Asah2 N-acylsphingosine amidohydrolase 2 involved_in ISO
IDA
(PMID:11278489), (PMID:17475390)
(MGI:6274955|PMID:21613224)
PMID:15123644
RGD PMID:11278489 PMID:17475390 PMID:21613224 PMID:15123644 PMID:11278489 MGI:6274955, RGD:13838793, RGD:13838803 NCBI chr 1:229,865,662...229,973,253
Ensembl chr 1:229,865,662...229,939,162
JBrowse link
G Cers1 ceramide synthase 1 involved_in ISO (PMID:12105227), (PMID:12869556), (PMID:15823095), (PMID:17548428), (PMID:18541923), (PMID:22922758), (PMID:24782409)
(MGI:3696321|PMID:16951403), (MGI:3764760|PMID:17977534), (MGI:5008665|PMID:21625621), (MGI:5755322|PMID:26620563), (MGI:6380950|PMID:30605666)
RGD PMID:12105227 PMID:12869556 PMID:15823095 PMID:16951403 PMID:17548428 More... MGI:3696321 MGI:3764760 MGI:5008665 MGI:5755322 MGI:6380950 NCBI chr16:19,097,309...19,112,519
Ensembl chr16:19,104,466...19,112,519
JBrowse link
G Cers2 ceramide synthase 2 involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:17977534), (PMID:18165233), (PMID:29632068)
(MGI:4421488|PMID:19801672), (MGI:5755322|PMID:26620563)
PMID:21873635
(MGI:3696894|PMID:15823095)
RGD PMID:15823095 PMID:17977534 PMID:18165233 PMID:19801672 PMID:26620563 More... MGI:3696894 MGI:4421488 MGI:5755322, RGD:13792537 NCBI chr 2:182,890,527...182,898,805
Ensembl chr 2:182,890,493...182,933,314
JBrowse link
G Cers3 ceramide synthase 3 involved_in ISO
IBA
(PMID:17977534), (PMID:22038835), (PMID:23754960)
PMID:21873635
(MGI:5303015|PMID:22038835)
RGD PMID:17977534 PMID:22038835 PMID:23754960 PMID:21873635 MGI:5303015, RGD:13792537 NCBI chr 1:120,316,930...120,422,926
Ensembl chr 1:120,318,212...120,422,902
JBrowse link
G Cers4 ceramide synthase 4 involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:17977534), (PMID:29632068)
PMID:21873635
(MGI:2679796|PMID:12912983), (MGI:3696894|PMID:15823095)
RGD PMID:12912983 PMID:15823095 PMID:17977534 PMID:29632068 PMID:21873635 MGI:2679796 MGI:3696894, RGD:13792537 NCBI chr12:2,851,784...2,890,244
Ensembl chr12:2,851,784...2,886,828
JBrowse link
G Cers5 ceramide synthase 5 involved_in ISO
IBA
(PMID:16951403), (PMID:29632068)
PMID:21873635
(MGI:3696624|PMID:16100120), (MGI:3722529|PMID:17609214), (MGI:3764760|PMID:17977534)
RGD PMID:16100120 PMID:16951403 PMID:17609214 PMID:17977534 PMID:29632068 More... MGI:3696624 MGI:3722529 MGI:3764760, RGD:13792537 NCBI chr 7:130,859,993...130,897,979
Ensembl chr 7:130,859,990...130,897,947
JBrowse link
G Cers6 ceramide synthase 6 involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:17609214), (PMID:17977534)
PMID:21873635
(MGI:5513027|PMID:23760501), (MGI:5755322|PMID:26620563)
(MGI:3696894|PMID:15823095)
RGD PMID:15823095 PMID:17609214 PMID:17977534 PMID:23760501 PMID:26620563 More... MGI:3696894 MGI:5513027 MGI:5755322, RGD:13792537 NCBI chr 3:53,630,636...53,879,692
Ensembl chr 3:53,630,959...53,876,848
JBrowse link
G Cyp4f39 cytochrome P450, family 4, subfamily f, polypeptide 39 involved_in IBA
ISO
PMID:21873635
(PMID:26056268)
RGD PMID:26056268 PMID:21873635 RGD:13792537 NCBI chr 7:11,426,806...11,505,553
Ensembl chr 7:11,433,371...11,536,181
JBrowse link
G Degs1 delta(4)-desaturase, sphingolipid 1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:3529540 (MGI:5466789|PMID:22984457)
RGD PMID:22984457 PMID:21873635 MGI:5466789, RGD:13792537 NCBI chr13:93,946,154...93,953,677
Ensembl chr13:93,946,157...93,953,664
JBrowse link
G Degs2 delta(4)-desaturase, sphingolipid 2 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:3694278|PMID:16571104)
RGD PMID:16571104 PMID:21873635 MGI:3694278, RGD:13792537 NCBI chr 6:127,596,063...127,613,293
Ensembl chr 6:127,596,071...127,613,293
JBrowse link
G Elovl1 ELOVL fatty acid elongase 1 involved_in ISO (MGI:5532629|PMID:23689133) RGD PMID:23689133 MGI:5532629 NCBI chr 5:131,961,478...131,965,961
Ensembl chr 5:131,961,322...131,965,958
JBrowse link
G Fa2h fatty acid 2-hydroxylase involved_in ISO
ISS
(PMID:15337768)
(MGI:6245295|PMID:22517924)
GO_REF:0000024
RGD
UniProt
PMID:15337768 PMID:22517924 GO_REF:0000024 MGI:6245295 NCBI chr19:39,312,904...39,364,153
Ensembl chr19:39,312,906...39,364,153
JBrowse link
G Gba glucosylceramidase beta involved_in ISO (PMID:19279011) RGD PMID:19279011 NCBI chr 2:174,609,437...174,615,457
Ensembl chr 2:174,609,403...174,618,263
JBrowse link
G LOC498300 similar to degenerative spermatocyte homolog involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:92,772,654...92,818,811
Ensembl chr13:92,772,649...92,818,574
JBrowse link
G P2rx1 purinergic receptor P2X 1 acts_upstream_of_or_within ISO (MGI:3640029|PMID:16325464) RGD PMID:16325464 MGI:3640029 NCBI chr10:57,618,586...57,633,648
Ensembl chr10:57,618,586...57,633,623
JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO (MGI:3640029|PMID:16325464) RGD PMID:16325464 MGI:3640029 NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619
JBrowse link
G Pnpla1 patatin-like phospholipase domain containing 1 involved_in ISO (PMID:27751867)
(MGI:5882269|PMID:27751867)
RGD PMID:27751867 MGI:5882269 NCBI chr20:6,918,446...6,951,650
Ensembl chr20:6,917,931...6,952,375
JBrowse link
G RGD1564463 similar to Mdes protein involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:92,831,549...92,839,257
Ensembl chr13:92,831,537...92,839,246
JBrowse link
G Samd8 sterile alpha motif domain containing 8 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:5749225 (MGI:5632043|PMID:25605874), (MGI:5707904|PMID:25667419)
(PMID:19506037)
RGD PMID:19506037 PMID:25605874 PMID:25667419 PMID:21873635 MGI:5632043 MGI:5707904, RGD:13792537 NCBI chr15:2,512,104...2,562,368
Ensembl chr15:2,512,105...2,515,379
Ensembl chr15:2,512,105...2,515,379
JBrowse link
G Sgms1 sphingomyelin synthase 1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(PMID:25605874)
(MGI:5632043|PMID:25605874)
RGD PMID:25605874 PMID:21873635 MGI:5632043, RGD:13792537 NCBI chr 1:229,996,673...230,259,591
Ensembl chr 1:229,998,119...230,259,603
JBrowse link
G Sgms2 sphingomyelin synthase 2 involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
GO_REF:0000107
MGI:4818459 (MGI:5632043|PMID:25605874)
PMID:21873635
Ensembl
RGD
PMID:25605874 PMID:21873635 GO_REF:0000107 MGI:5632043, RGD:13792537 NCBI chr 2:219,889,809...219,967,704
Ensembl chr 2:219,893,572...219,967,546
JBrowse link
G Smpd1 sphingomyelin phosphodiesterase 1 involved_in IMP
ISO
IBA
(MGI:82530|PMID:8706124)
(PMID:17303575), (PMID:18815062), (PMID:19279011), (PMID:20807762), (PMID:8706124)
PMID:21873635
RGD PMID:8706124 PMID:17303575 PMID:18815062 PMID:19279011 PMID:20807762 More... MGI:82530, RGD:1601344, RGD:13792537 NCBI chr 1:159,892,946...159,896,789
Ensembl chr 1:159,892,859...159,896,794
JBrowse link
G Smpd2 sphingomyelin phosphodiesterase 2 involved_in IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:12473648 PMID:21873635 RGD:1581395, RGD:13792537 NCBI chr20:44,986,229...44,989,343
Ensembl chr20:44,986,231...44,989,441
JBrowse link
G Smpd4 sphingomyelin phosphodiesterase 4 involved_in ISO
IBA
(PMID:16517606), (PMID:25180167)
(MGI:6450503|PMID:25180167)
PMID:21873635
RGD PMID:16517606 PMID:25180167 PMID:21873635 MGI:6450503, RGD:13792537 NCBI chr11:83,362,534...83,386,257
Ensembl chr11:83,362,534...83,386,250
JBrowse link
G Smpd5 sphingomyelin phosphodiesterase 5 involved_in ISO (MGI:6450238|PMID:21183079) RGD PMID:21183079 MGI:6450238 NCBI chr 7:108,009,182...108,011,767
Ensembl chr 7:108,009,173...108,011,763
JBrowse link
G Sptlc1 serine palmitoyltransferase, long chain base subunit 1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(PMID:25691431)
MGI:3815115 (MGI:3814228|PMID:16216550)
RGD PMID:16216550 PMID:25691431 PMID:21873635 MGI:3814228, RGD:13792537 NCBI chr17:11,877,249...11,916,295
Ensembl chr17:11,877,249...11,916,295
JBrowse link
G Sptlc2 serine palmitoyltransferase, long chain base subunit 2 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(PMID:25691431)
MGI:3815117 (MGI:3814228|PMID:16216550)
RGD PMID:16216550 PMID:25691431 PMID:21873635 MGI:3814228, RGD:13792537 NCBI chr 6:106,948,681...107,031,584
Ensembl chr 6:106,950,949...107,031,542
JBrowse link
G Sptlc3 serine palmitoyltransferase, long chain base subunit 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:126,847,878...126,978,010
Ensembl chr 3:126,847,878...126,978,010
JBrowse link
G Sptssa serine palmitoyltransferase, small subunit A involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(PMID:25691431)
RGD PMID:25691431 PMID:21873635 RGD:13792537 NCBI chr 6:72,144,714...72,156,130
Ensembl chr 6:72,144,714...72,156,214
JBrowse link
G Sptssb serine palmitoyltransferase, small subunit B involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:5689843 (MGI:5689923|PMID:26438849)
RGD PMID:26438849 PMID:21873635 MGI:5689923, RGD:13792537 NCBI chr 2:154,133,728...154,162,127
Ensembl chr 2:154,133,733...154,163,120
JBrowse link
G Tlcd3b TLC domain containing 3B involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:5490837|PMID:23275342)
RGD PMID:23275342 PMID:21873635 MGI:5490837, RGD:13792537 NCBI chr 1:181,421,104...181,439,744
Ensembl chr 1:181,422,830...181,439,743
JBrowse link
galactosylceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B3galt1 Beta-1,3-galactosyltransferase 1 involved_in ISO (PMID:9582303) RGD PMID:9582303 NCBI chr 3:52,253,413...52,826,508
Ensembl chr 3:52,253,618...52,825,313
JBrowse link
G B3galt2 Beta-1,3-galactosyltransferase 2 involved_in ISO (PMID:9582303) RGD PMID:9582303 NCBI chr13:55,389,406...55,398,419
Ensembl chr13:55,389,406...55,398,419
JBrowse link
G B4galt3 beta-1,4-galactosyltransferase 3 involved_in IBA
ISO
PMID:21873635
(PMID:9405390)
RGD PMID:9405390 PMID:21873635 RGD:13792537 NCBI chr13:83,691,378...83,697,448
Ensembl chr13:83,691,446...83,697,448
JBrowse link
G Fa2h fatty acid 2-hydroxylase involved_in ISS
ISO
IMP
IEA
GO_REF:0000024
(MGI:3696647|PMID:15658937), (MGI:3826747|PMID:18815260)
PMID:17901466
GO_REF:0000041
UniProt
RGD
PMID:15658937 PMID:18815260 PMID:17901466 GO_REF:0000024 GO_REF:0000041 MGI:3696647 MGI:3826747, RGD:13825191 NCBI chr19:39,312,904...39,364,153
Ensembl chr19:39,312,906...39,364,153
JBrowse link
G Gal3st1 galactose-3-O-sulfotransferase 1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:1355015|PMID:10727929)
RGD PMID:10727929 PMID:21873635 MGI:1355015, RGD:13792537 NCBI chr14:78,868,049...78,886,402
Ensembl chr14:78,870,793...78,886,388
JBrowse link
G Ugt8 UDP glycosyltransferase 8 involved_in IDA
IEA
PMID:8713090
GO_REF:0000041
UniProt PMID:8713090 GO_REF:0000041, RGD:39458006 NCBI chr 2:214,264,483...214,332,769
Ensembl chr 2:214,264,483...214,332,660
JBrowse link
ganglioside biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07013843.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G B3galt4 Beta-1,3-galactosyltransferase 4 involved_in ISO
IEA
(PMID:9582303)
GO_REF:0000107
RGD
Ensembl
PMID:9582303 GO_REF:0000107 NCBI chr20:4,936,089...4,937,664
Ensembl chr20:4,931,768...4,938,315
JBrowse link
G B4galnt1 beta-1,4-N-acetyl-galactosaminyl transferase 1 involved_in
acts_upstream_of_or_within
IBA
ISO
IDA
ISS
PMID:21873635
(MGI:83232|PMID:8855236)
MGI:2158349|MGI:96074 (MGI:1331265|PMID:10021458)
PMID:3140234
(PMID:1601877), (PMID:7487055), (PMID:7890749)
GO_REF:0000024
RGD
UniProt
PMID:1601877 PMID:7487055 PMID:7890749 PMID:8855236 PMID:10021458 More... GO_REF:0000024 MGI:1331265 MGI:83232, RGD:13792537, RGD:21201261 NCBI chr 7:62,988,429...62,996,190
Ensembl chr 7:62,988,930...62,996,190
JBrowse link
G St6galnac3 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:242,129,755...242,645,120
Ensembl chr 2:242,129,763...242,645,133
JBrowse link
G St6galnac4 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:15,872,230...15,885,250
Ensembl chr 3:15,872,532...15,885,243
JBrowse link
G St6galnac5 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:241,741,933...241,911,214
Ensembl chr 2:241,742,688...241,911,208
JBrowse link
G St6galnac6 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:1354410|PMID:10702226)
RGD PMID:10702226 PMID:21873635 MGI:1354410, RGD:13792537 NCBI chr 3:15,894,278...15,907,502
Ensembl chr 3:15,885,968...15,907,496
JBrowse link
G St8sia2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 involved_in ISO (PMID:10766765) RGD PMID:10766765 NCBI chr 1:127,766,669...127,838,017
Ensembl chr 1:127,762,573...127,838,091
JBrowse link
G St8sia3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 involved_in ISO (PMID:10766765) RGD PMID:10766765 NCBI chr18:57,754,349...57,760,839
Ensembl chr18:57,754,347...57,760,839
JBrowse link
G St8sia4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 involved_in ISO (PMID:10766765) RGD PMID:10766765 NCBI chr 9:95,994,150...96,084,617
Ensembl chr 9:95,993,503...96,084,653
JBrowse link
G St8sia6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 involved_in ISO (MGI:2182536|PMID:11980897) RGD PMID:11980897 MGI:2182536 NCBI chr17:76,740,755...76,883,766
Ensembl chr17:76,745,224...76,884,299
JBrowse link
ganglioside biosynthetic process via lactosylceramide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B4galt5 beta-1,4-galactosyltransferase 5 involved_in ISO (MGI:6196231|PMID:30114188) RGD PMID:30114188 MGI:6196231 NCBI chr 3:156,018,056...156,033,983
Ensembl chr 3:156,018,053...156,070,074
JBrowse link
G B4galt6 beta-1,4-galactosyltransferase 6 involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:6196231|PMID:30114188)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:30114188 GO_REF:0000024 GO_REF:0000107 MGI:6196231 NCBI chr18:11,958,382...12,015,247
Ensembl chr18:11,958,390...12,015,247
JBrowse link
G St3gal1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 involved_in ISO (PMID:8027041)
(MGI:65558|PMID:8144500)
RGD PMID:8027041 PMID:8144500 MGI:65558 NCBI chr 7:98,845,270...98,913,409
Ensembl chr 7:98,845,270...98,913,236
JBrowse link
G St3gal2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 involved_in IDA
IEA
ISO
PMID:8144500
GO_REF:0000107
(MGI:6467685|PMID:22735313), (MGI:65558|PMID:8144500)
(PMID:8920913)
Ensembl
RGD
PMID:8144500 PMID:8920913 PMID:22735313 PMID:8144500 GO_REF:0000107 MGI:6467685 MGI:65558, RGD:68307 NCBI chr19:38,888,851...38,939,874
Ensembl chr19:38,923,999...38,939,869
JBrowse link
G St3gal3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 involved_in IEA
ISO
GO_REF:0000107
(MGI:6467685|PMID:22735313)
Ensembl
RGD
PMID:22735313 GO_REF:0000107 MGI:6467685 NCBI chr 5:131,470,348...131,670,794
Ensembl chr 5:131,470,348...131,670,810
JBrowse link
glucosylceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fa2h fatty acid 2-hydroxylase involved_in ISS
ISO
GO_REF:0000024
(MGI:5285470|PMID:21628453)
UniProt
RGD
PMID:21628453 GO_REF:0000024 MGI:5285470 NCBI chr19:39,312,904...39,364,153
Ensembl chr19:39,312,906...39,364,153
JBrowse link
G Ugcg UDP-glucose ceramide glucosyltransferase involved_in IBA
ISO
ISS
PMID:21873635
(MGI:2180222|PMID:10430909), (MGI:3603060|PMID:16109770), (MGI:5448789|PMID:22851168), (MGI:5510915|PMID:23748427)
GO_REF:0000024
(PMID:8643456)
RGD
UniProt
PMID:8643456 PMID:10430909 PMID:16109770 PMID:22851168 PMID:23748427 More... GO_REF:0000024 MGI:2180222 MGI:3603060 MGI:5448789 MGI:5510915, RGD:13792537 NCBI chr 5:74,032,978...74,065,701
Ensembl chr 5:74,032,978...74,065,393
JBrowse link
lactosylceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B4galt4 beta-1,4-galactosyltransferase 4 involved_in ISO (PMID:9792633) RGD PMID:9792633 NCBI chr11:61,995,807...62,021,751
Ensembl chr11:61,995,814...62,021,671
JBrowse link
G B4galt6 beta-1,4-galactosyltransferase 6 involved_in ISO (PMID:10320813) RGD PMID:10320813 NCBI chr18:11,958,382...12,015,247
Ensembl chr18:11,958,390...12,015,247
JBrowse link
negative regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ormdl1 ORMDL sphingolipid biosynthesis regulator 1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(PMID:25691431)
RGD PMID:25691431 PMID:21873635 RGD:13792537 NCBI chr 9:48,243,365...48,253,316
Ensembl chr 9:48,237,572...48,253,211
JBrowse link
G Ormdl2 ORMDL sphingolipid biosynthesis regulator 2 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(PMID:25691431)
RGD PMID:25691431 PMID:21873635 RGD:13792537 NCBI chr 7:1,247,869...1,250,999
Ensembl chr 7:1,246,479...1,250,907
JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
PMID:21873635
GO_REF:0000107
(PMID:25691431)
(MGI:5638294|PMID:25691431)
Ensembl
RGD
PMID:25691431 PMID:21873635 GO_REF:0000107 MGI:5638294, RGD:13792537 NCBI chr10:83,590,052...83,598,620
Ensembl chr10:83,590,071...83,598,620
JBrowse link
G Sphk1 sphingosine kinase 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(MGI:6294167|PMID:16118219)
(PMID:16118219)
UniProt
Ensembl
RGD
PMID:16118219 GO_REF:0000024 GO_REF:0000107 MGI:6294167 NCBI chr10:101,758,567...101,764,240
Ensembl chr10:101,758,711...101,764,240
JBrowse link
omega-hydroxyceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pnpla1 patatin-like phospholipase domain containing 1 involved_in ISO (PMID:28248318)
(MGI:5888934|PMID:28248300)
RGD PMID:28248300 PMID:28248318 MGI:5888934 NCBI chr20:6,918,446...6,951,650
Ensembl chr20:6,917,931...6,952,375
JBrowse link
positive regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccn1 cellular communication network factor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3849354|PMID:19364818)
Ensembl
RGD
PMID:19364818 GO_REF:0000107 MGI:3849354 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484
JBrowse link
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 involved_in ISS
ISO
GO_REF:0000024
(MGI:4947032|PMID:21177474)
UniProt
RGD
PMID:21177474 GO_REF:0000024 MGI:4947032 NCBI chr10:104,242,223...104,246,589
Ensembl chr10:104,242,223...104,246,589
JBrowse link
G Pla2g6 phospholipase A2 group VI involved_in IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:18936091 PMID:21873635 RGD:6482750, RGD:13792537 NCBI chr 7:110,851,378...110,891,557
Ensembl chr 7:110,851,378...110,891,114
JBrowse link
G Prkcd protein kinase C, delta involved_in ISO
IEA
(PMID:19279011)
GO_REF:0000107
RGD
Ensembl
PMID:19279011 GO_REF:0000107 NCBI chr16:5,769,226...5,807,214
Ensembl chr16:5,769,215...5,799,352
JBrowse link
G Sirt3 sirtuin 3 involved_in ISO (MGI:5755322|PMID:26620563) RGD PMID:26620563 MGI:5755322 NCBI chr 1:195,942,066...195,964,472
Ensembl chr 1:195,942,073...195,964,808
JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 IMP RGD PMID:20096352 RGD:10041064 NCBI chr19:34,162,337...34,245,786
Ensembl chr19:34,162,341...34,245,749
JBrowse link
G Sphk2 sphingosine kinase 2 involved_in ISO (PMID:16118219)
(MGI:6294167|PMID:16118219)
RGD PMID:16118219 MGI:6294167 NCBI chr 1:96,180,872...96,188,592
Ensembl chr 1:96,180,887...96,188,391
JBrowse link
regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ormdl1 ORMDL sphingolipid biosynthesis regulator 1 acts_upstream_of ISO MGI:1913862 (MGI:6393026|PMID:31880535) RGD PMID:31880535 MGI:6393026 NCBI chr 9:48,243,365...48,253,316
Ensembl chr 9:48,237,572...48,253,211
JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 acts_upstream_of ISO MGI:2137691|MGI:2181669|MGI:6382064 (MGI:6393026|PMID:31880535) RGD PMID:31880535 MGI:6393026 NCBI chr10:83,590,052...83,598,620
Ensembl chr10:83,590,071...83,598,620
JBrowse link
G Prkcd protein kinase C, delta involved_in ISO
ISS
(PMID:17303575)
GO_REF:0000024
RGD
UniProt
PMID:17303575 GO_REF:0000024 NCBI chr16:5,769,226...5,807,214
Ensembl chr16:5,769,215...5,799,352
JBrowse link
G Samd8 sterile alpha motif domain containing 8 involved_in ISO (PMID:19506037) RGD PMID:19506037 NCBI chr15:2,512,104...2,562,368
Ensembl chr15:2,512,105...2,515,379
Ensembl chr15:2,512,105...2,515,379
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19497
    metabolic process 11824
      cellular metabolic process 10719
        cellular nitrogen compound metabolic process 6560
          cellular amide metabolic process 1500
            amide biosynthetic process 1193
              ceramide biosynthetic process 69
                ganglioside biosynthetic process + 16
                glycosylceramide biosynthetic process + 7
                isogloboside biosynthetic process 0
                lactosylceramide biosynthetic process 2
                negative regulation of ceramide biosynthetic process + 4
                omega-hydroxyceramide biosynthetic process 1
                positive regulation of ceramide biosynthetic process + 7
                regulation of ceramide biosynthetic process + 12
Path 2
Term Annotations click to browse term
  biological_process 19497
    metabolic process 11824
      primary metabolic process 10535
        lipid metabolic process 1388
          cellular lipid metabolic process 1035
            membrane lipid metabolic process 193
              sphingolipid metabolic process 147
                sphingolipid biosynthetic process 97
                  ceramide biosynthetic process 69
                    ganglioside biosynthetic process + 16
                    glycosylceramide biosynthetic process + 7
                    isogloboside biosynthetic process 0
                    lactosylceramide biosynthetic process 2
                    negative regulation of ceramide biosynthetic process + 4
                    omega-hydroxyceramide biosynthetic process 1
                    positive regulation of ceramide biosynthetic process + 7
                    regulation of ceramide biosynthetic process + 12
paths to the root