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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Mycobacterium avium complex disease
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Accession:DOID:2755 term browser browse the term
Definition:A primary bacterial infectious disease that results_in infection, has_material_basis_in Mycobacterium avium complex (MAC), which is transmitted_by inhalation or transmitted_by ingestion of via the respiratory or gastrointestinal tract respectively. The bacteria cause disseminated infection in HIV infected people, while pulmonary disease in immunocompetent persons. (DO)
Synonyms:exact_synonym: Infection due to Mycobacterium intracellulare;   MAC disease;   Mycobacterium Avium-Intracellulare Infection;   Mycobacterium avium complex;   Mycobacterium avium infection;   Mycobacterium avium-intracellulare Infections;   Mycobacterium intracellulare Infection;   Mycobacterium intracellulare Infections
 primary_id: MESH:D015270
 xref: EFO:0007386;   GARD:7123;   NCI:C36197
For additional species annotation, visit the Alliance of Genome Resources.


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Mycobacterium avium complex disease term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing ISO associated with pulmonary diseases; protein:increased expression:serum RGD PMID:19641295 RGD:5686838 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Il17a interleukin 17A ISO RGD PMID:20797909 RGD:4888520 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889 		JBrowse link
G Tnf tumor necrosis factor ISO associated with HIV Infections RGD PMID:7640175 RGD:10450731 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19087
    disease by infectious agent 2249
      Bacterial Infections and Mycoses 1116
        bacterial infectious disease 824
          primary bacterial infectious disease 197
            Mycobacterium avium complex disease 3
Path 2
Term Annotations click to browse term
  disease 19087
    disease by infectious agent 2249
      Bacterial Infections and Mycoses 1116
        bacterial infectious disease 824
          Gram-Positive Bacterial Infections 395
            Actinomycetales Infections 320
              Mycobacterium Infections 319
                Nontuberculous Mycobacterium Infections 151
                  Mycobacterium avium complex disease 3
paths to the root