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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:childhood acute myeloid leukemia
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Accession:DOID:0070323 term browser browse the term
Definition:A childhood leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells. (DO)
Synonyms:exact_synonym: childhood acute myeloid leukaemia;   paediatric acute myeloid leukaemia;   pediatric acute myeloid leukemia
 narrow_synonym: childhood acute myeloid leukemia with maturation
 xref: EFO:0000330;   EFO:1001945;   ICD-O:M9861/3;   NCI:C9160


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childhood acute myeloid leukemia term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IER2 immediate early response 2 ISO mRNA:increased expression:bone marrow (human) RGD PMID:34702297 RGD:153323323 NCBI chr19:12,714,804...12,718,213
Ensembl chr19:13,452,239...13,452,910 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15684
    disease of cellular proliferation 7263
      Neoplasms by Histologic Type 5078
        leukemia 592
          childhood leukemia 1
            childhood acute myeloid leukemia 1
Path 2
Term Annotations click to browse term
  disease 15684
    disease of anatomical entity 15295
      Hemic and Lymphatic Diseases 3704
        hematopoietic system disease 3220
          Hematologic Neoplasms 990
            hematologic cancer 990
              leukemia 592
                myeloid leukemia 391
                  acute myeloid leukemia 322
                    childhood acute myeloid leukemia 1
paths to the root