Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References FTP Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) RatMine GViewer (Genome Viewer) Overgo Probe Designer ACP Haplotyper Genome Scanner
Aging & Age-Related Disease Cancer Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:myeloid leukemia
go back to main search page
Accession:DOID:8692 term browser browse the term
Definition:Form of leukemia characterized by an uncontrolled proliferation of the myeloid lineage and their precursors (MYELOID PROGENITOR CELLS) in the bone marrow and other sites.
Synonyms:exact_synonym: Granulocytic Leukemia;   Myelocytic Leukemia;   Myelocytic Leukemias;   Myelogenous Leukemia;   Myelogenous Leukemias;   Myeloid Leukemias;   granulocytic leukemias;   leukaemia myelogenous;   myeloid granulocytic leukaemia;   myeloid granulocytic leukemia;   myeloid leukaemia;   non-lymphocytic leukemia
 narrow_synonym: chronic myeloid leukemia
 primary_id: MESH:D007951
 alt_id: OMIA:001573
 xref: GARD:8226;   ICD10CM:C92;   ICD9CM:205;   NCI:C21889;   NCI:C3172
For additional species annotation, visit the Alliance of Genome Resources.

show annotations for term's descendants           Sort by:
 
myeloid leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ago2 argonaute RISC catalytic component 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21535412 NCBI chr 7:114,339,607...114,377,277
Ensembl chr 7:114,339,434...114,380,613 		JBrowse link
G Atg2b autophagy related 2B ISO CTD Direct Evidence: marker/mechanism CTD PMID:26280900 NCBI chr 6:129,449,451...129,519,599
Ensembl chr 6:129,449,449...129,509,720 		JBrowse link
G Camlg calcium modulating ligand ISO mRNA:increased expression:bone marrow (human) RGD PMID:12031912 RGD:2316229 NCBI chr17:9,523,792...9,534,683
Ensembl chr17:9,523,795...9,534,653 		JBrowse link
G Cbx7 chromobox 7 treatment ISO RGD PMID:26343356 RGD:11352715 NCBI chr 7:121,136,067...121,153,503
Ensembl chr 7:121,136,058...121,153,383 		JBrowse link
G Csf3 colony stimulating factor 3 disease_progression ISO RGD PMID:7510191 RGD:11039040 NCBI chr10:86,616,785...86,619,160
Ensembl chr10:86,616,785...86,619,157 		JBrowse link
G Dhfr dihydrofolate reductase ISO RGD PMID:12649191 RGD:11039541 NCBI chr 2:21,931,887...21,958,927
Ensembl chr 2:21,931,493...21,962,453 		JBrowse link
G Erg ETS transcription factor ERG ISO RGD PMID:23719302 RGD:10450751 NCBI chr11:35,645,317...35,749,637
Ensembl chr11:35,646,116...35,749,594 		JBrowse link
G Esr2 estrogen receptor 2 ISO RGD PMID:12740446 RGD:734951 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251 		JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 ISO RGD PMID:19506298 RGD:11352666 NCBI chr16:71,265,390...71,319,046
Ensembl chr16:71,266,248...71,319,449 		JBrowse link
G Flt3 Fms related receptor tyrosine kinase 3 ISO RGD PMID:17936561 RGD:11049465 NCBI chr12:9,360,439...9,437,004
Ensembl chr12:9,360,672...9,436,570 		JBrowse link
G Gata1 GATA binding protein 1 ISO RGD PMID:23719302 RGD:10450751 NCBI chr  X:15,273,937...15,281,759
Ensembl chr  X:15,378,789...15,382,066 		JBrowse link
G Gata2 GATA binding protein 2 disease_progression ISO DNA:missense mutation:cds:p.L359V RGD PMID:19304323 RGD:11049517 NCBI chr 4:120,129,028...120,142,490
Ensembl chr 4:120,133,713...120,142,488 		JBrowse link
G Gfi1 growth factor independent 1 transcriptional repressor ISO RGD PMID:21732494 RGD:11040451 NCBI chr14:3,058,035...3,073,332
Ensembl chr14:3,058,993...3,068,371 		JBrowse link
G Gskip GSK3B interacting protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:26280900 NCBI chr 6:129,512,950...129,536,320
Ensembl chr 6:129,519,709...129,536,221 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 disease_progression ISO RGD PMID:11906705, PMID:16313269 RGD:10755328, RGD:10755403 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 susceptibility ISO DNA:SNP:cds:p.I105V (rs1695) (human) RGD PMID:20843134 RGD:10755535 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147 		JBrowse link
G Gstt1 glutathione S-transferase theta 1 susceptibility
no_association
disease_progression		 ISO RGD PMID:21254556, PMID:16313269, PMID:18760837 RGD:10755324, RGD:10755403, RGD:10755327 NCBI chr20:13,799,102...13,816,527
Ensembl chr20:13,799,102...13,816,526 		JBrowse link
G Hdac2 histone deacetylase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21535412 NCBI chr20:43,084,870...43,108,198
Ensembl chr20:43,084,870...43,108,198 		JBrowse link
G Ifng interferon gamma treatment ISO RGD PMID:20959405 RGD:10755686 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419 		JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 ISO protein:decreased expression:blood: RGD PMID:23716272 RGD:12743616 NCBI chr14:87,457,647...87,465,374
Ensembl chr14:87,457,647...87,465,374 		JBrowse link
G Kmt2a lysine methyltransferase 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:8282816 PMID:17463288 NCBI chr 8:49,110,407...49,185,872
Ensembl chr 8:49,114,990...49,158,971 		JBrowse link
G Kmt2e lysine methyltransferase 2E ISO CTD Direct Evidence: marker/mechanism CTD PMID:18854576 NCBI chr 4:8,187,751...8,255,578
Ensembl chr 4:8,187,751...8,255,514 		JBrowse link
G Mecom MDS1 and EVI1 complex locus ISO CTD Direct Evidence: marker/mechanism CTD PMID:23770046 NCBI chr 2:117,396,084...117,993,604
Ensembl chr 2:117,396,007...117,454,769 		JBrowse link
G Mn1 MN1 proto-oncogene, transcriptional regulator ISO acute myeloid leukemia, DNA:translocation RGD PMID:7731705 RGD:1600424 NCBI chr12:51,214,192...51,250,230
Ensembl chr12:51,214,192...51,250,230 		JBrowse link
G Mpl MPL proto-oncogene, thrombopoietin receptor ISO mRNA:increased expression:peripheral blood mononuclear cell (human) RGD PMID:10621836 RGD:10449009 NCBI chr 5:137,268,412...137,282,032
Ensembl chr 5:137,269,480...137,281,298 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11882782 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180 		JBrowse link
G Nsd3 nuclear receptor binding SET domain protein 3 ISO RGD PMID:11986249 RGD:1599847 NCBI chr16:71,126,276...71,237,118
Ensembl chr16:71,130,668...71,237,118 		JBrowse link
G Pdgfra platelet derived growth factor receptor alpha ISO RGD PMID:24486648 RGD:11075087 NCBI chr14:35,527,926...35,581,130
Ensembl chr14:35,527,927...35,581,031 		JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 ISO mRNA:increased expression:blood (human) RGD PMID:23772643 RGD:11541098 NCBI chr10:94,850,971...94,913,202 JBrowse link
G Prame PRAME nuclear receptor transcriptional regulator severity ISO human cell line in a mouse model RGD PMID:16103086 RGD:11535036 NCBI chr  X:106,082,984...106,091,256
Ensembl chr  X:106,083,203...106,085,878 		JBrowse link
G Prdx2 peroxiredoxin 2 ISO CTD Direct Evidence: therapeutic CTD PMID:16932348 NCBI chr19:26,084,816...26,090,095
Ensembl chr19:26,084,903...26,090,094 		JBrowse link
G Rad21 RAD21 cohesin complex component ISO CTD Direct Evidence: marker/mechanism CTD PMID:23955599 NCBI chr 7:91,511,755...91,538,673
Ensembl chr 7:91,511,756...91,538,673 		JBrowse link
G Setbp1 SET binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23832012 NCBI chr18:75,090,733...75,432,446
Ensembl chr18:75,095,632...75,207,306 		JBrowse link
G Smarcd2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28369036 NCBI chr10:94,451,866...94,460,732
Ensembl chr10:94,451,866...94,460,732 		JBrowse link
G Smc1a structural maintenance of chromosomes 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:23955599 NCBI chr  X:21,710,976...21,755,708
Ensembl chr  X:21,711,019...21,755,525 		JBrowse link
G Smc3 structural maintenance of chromosomes 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23955599 NCBI chr 1:274,310,120...274,352,856
Ensembl chr 1:274,309,758...274,352,854 		JBrowse link
G Snca synuclein alpha ISO RGD PMID:21264917 RGD:6478703 NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285 		JBrowse link
G Spi1 Spi-1 proto-oncogene ISO CTD Direct Evidence: therapeutic CTD PMID:17361223 NCBI chr 3:79,918,127...79,937,708
Ensembl chr 3:79,918,969...79,938,301 		JBrowse link
G Srsf1 serine and arginine rich splicing factor 1 ISO mRNA:increased expression:peripheral blood mononuclear cell (human) RGD PMID:23228155 RGD:11038774 NCBI chr10:75,334,200...75,341,197
Ensembl chr10:75,335,146...75,341,197 		JBrowse link
G Stag2 stromal antigen 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23955599 NCBI chr  X:128,493,603...128,624,418
Ensembl chr  X:128,493,614...128,624,418 		JBrowse link
G Top2b DNA topoisomerase II beta ISO CTD Direct Evidence: therapeutic CTD PMID:16932348 NCBI chr15:10,262,972...10,319,741
Ensembl chr15:10,262,651...10,320,233 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 treatment ISO DNA:polymorphism: : RGD PMID:23609856 RGD:10768829 NCBI chr 9:95,295,701...95,302,822
Ensembl chr 9:95,161,157...95,302,822 		JBrowse link
G Vegfa vascular endothelial growth factor A ISO CTD Direct Evidence: marker/mechanism CTD PMID:21535412 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681 		JBrowse link
Acute Erythroblastic Leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase ISO CTD Direct Evidence: marker/mechanism CTD PMID:38827 NCBI chr 6:26,657,507...26,680,459
Ensembl chr 6:26,657,780...26,680,284 		JBrowse link
G Dhodh dihydroorotate dehydrogenase (quinone) ISO CTD Direct Evidence: marker/mechanism CTD PMID:38827 NCBI chr19:42,066,103...42,087,906
Ensembl chr19:42,066,351...42,082,012 		JBrowse link
G Umps uridine monophosphate synthetase ISO CTD Direct Evidence: marker/mechanism CTD PMID:38827 NCBI chr11:70,034,181...70,044,590
Ensembl chr11:70,034,139...70,044,628 		JBrowse link
Acute Erythroleukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddx41 DEAD-box helicase 41 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30926971 NCBI chr17:9,631,925...9,637,317
Ensembl chr17:9,631,925...9,637,316 		JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 ISO ClinVar Annotator: match by term: Acute erythroleukemia ClinVar PMID:27416908 NCBI chr 7:2,989,202...3,010,610
Ensembl chr 7:2,989,340...3,010,350 		JBrowse link
G Flt3 Fms related receptor tyrosine kinase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30926971 NCBI chr12:9,360,439...9,437,004
Ensembl chr12:9,360,672...9,436,570 		JBrowse link
G Gfi1b growth factor independent 1B transcriptional repressor ISO mRNA:increased expression:bone marrow cell: RGD PMID:17156408 RGD:11040507 NCBI chr 3:7,190,721...7,203,444
Ensembl chr 3:7,190,722...7,203,420 		JBrowse link
G Hoxb9 homeo box B9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30926971 NCBI chr10:84,119,772...84,124,963
Ensembl chr10:84,119,884...84,123,390 		JBrowse link
G Kmt2a lysine methyltransferase 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:30926971 NCBI chr 8:49,110,407...49,185,872
Ensembl chr 8:49,114,990...49,158,971 		JBrowse link
G Npm1 nucleophosmin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30926971 NCBI chr10:18,080,949...18,091,062
Ensembl chr10:18,080,950...18,090,950 		JBrowse link
G Nup98 nucleoporin 98 and 96 precursor ISO CTD Direct Evidence: marker/mechanism CTD PMID:30926971 NCBI chr 1:167,213,866...167,308,851
Ensembl chr 1:167,213,866...167,308,851 		JBrowse link
G Rb1 RB transcriptional corepressor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30926971 NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342 		JBrowse link
G Tp53 tumor protein p53 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30926971 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449 		JBrowse link
acute megakaryocytic leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg2 ATP binding cassette subfamily G member 2 ISO RGD PMID:21640380 RGD:11081147 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621 		JBrowse link
G Apc APC regulator of WNT signaling pathway ISO ClinVar Annotator: match by term: Acute megakaryoblastic leukemia ClinVar PMID:25741868 PMID:28492532 NCBI chr18:27,011,710...27,106,323
Ensembl chr18:27,047,382...27,105,531 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 ISO CTD Direct Evidence: therapeutic CTD PMID:16166298 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413 		JBrowse link
G Coro7 coronin 7 ISO ClinVar Annotator: match by term: Acute megakaryoblastic leukemia ClinVar NCBI chr10:11,090,200...11,144,289
Ensembl chr10:11,090,314...11,143,881
Ensembl chr10:11,090,314...11,143,881 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit ISO associated with Down Syndrome;DNA:mutations:multiple (human) RGD PMID:24056718 RGD:10450890 NCBI chr 4:77,284,404...77,347,011
Ensembl chr 4:77,284,404...77,347,011 		JBrowse link
G Gata1 GATA binding protein 1 ISO ClinVar Annotator: match by term: Acute megakaryoblastic leukemia ClinVar PMID:15070711 NCBI chr  X:15,273,937...15,281,759
Ensembl chr  X:15,378,789...15,382,066 		JBrowse link
G Gfi1b growth factor independent 1B transcriptional repressor ISO mRNA:increased expression:bone marrow cell: RGD PMID:17156408 RGD:11040507 NCBI chr 3:7,190,721...7,203,444
Ensembl chr 3:7,190,722...7,203,420 		JBrowse link
G Jak3 Janus kinase 3 ISO ClinVar Annotator: match by term: Acute megakaryoblastic leukemia ClinVar PMID:10982185 PMID:16843266 PMID:18270328 PMID:18397343 PMID:20132407 PMID:20372971 PMID:20385788 PMID:20400977 PMID:21599579 PMID:21821710 PMID:22271575 PMID:24728327 PMID:25157968 PMID:28492532, PMID:16843266 RGD:11531113 NCBI chr16:20,107,471...20,120,678
Ensembl chr16:20,109,200...20,120,668 		JBrowse link
G Mdga1 MAM domain containing glycosylphosphatidylinositol anchor 1 ISO ClinVar Annotator: match by term: Acute megakaryoblastic leukemia ClinVar NCBI chr20:8,515,142...8,574,632
Ensembl chr20:8,515,142...8,574,082 		JBrowse link
G Mrtfa myocardin related transcription factor A ISO RGD PMID:11431691 RGD:1599948 NCBI chr 7:122,233,196...122,403,661
Ensembl chr 7:122,234,012...122,403,667 		JBrowse link
G Mt-nd6 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 ISO ClinVar Annotator: match by term: Acute megakaryoblastic leukemia ClinVar NCBI chr MT:13,543...14,061
Ensembl chr MT:13,543...14,061 		JBrowse link
G Pcf11 PCF11 cleavage and polyadenylation factor subunit ISO ClinVar Annotator: match by term: Acute megakaryoblastic leukemia ClinVar NCBI chr 1:157,463,014...157,494,134
Ensembl chr 1:157,468,626...157,494,008 		JBrowse link
G Prame PRAME nuclear receptor transcriptional regulator ISO associated with Down Syndrome;mRNA:increased expression:mononuclear cell (human) RGD PMID:15180862 RGD:11535064 NCBI chr  X:106,082,984...106,091,256
Ensembl chr  X:106,083,203...106,085,878 		JBrowse link
G Pten phosphatase and tensin homolog ISO ClinVar Annotator: match by term: Acute megakaryoblastic leukemia ClinVar PMID:10848731 PMID:17941496 PMID:20600018 PMID:21194675 PMID:21343951 PMID:21659347 PMID:22281088 PMID:22520842 PMID:23335809 PMID:23475934 PMID:23886400 PMID:24778394 PMID:26376867 PMID:28492532 PMID:29663862 NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832 		JBrowse link
G Rasal3 RAS protein activator like 3 ISO ClinVar Annotator: match by term: Acute megakaryoblastic leukemia ClinVar NCBI chr 7:14,403,592...14,419,570
Ensembl chr 7:14,403,592...14,418,950 		JBrowse link
G Runx1 RUNX family transcription factor 1 onset ISO RGD PMID:15856017 RGD:11251701 NCBI chr11:32,765,147...33,003,061
Ensembl chr11:32,769,165...33,003,021 		JBrowse link
G Slc9a2 solute carrier family 9 member A2 ISO ClinVar Annotator: match by term: Acute megakaryoblastic leukemia ClinVar NCBI chr 9:47,386,581...47,491,813
Ensembl chr 9:47,386,626...47,491,907 		JBrowse link
G Sncb synuclein, beta ISO RGD PMID:21264917 RGD:6478703 NCBI chr17:10,384,472...10,392,776
Ensembl chr17:10,384,511...10,392,843 		JBrowse link
G Tp53 tumor protein p53 ISO ClinVar Annotator: match by term: Acute megakaryoblastic leukemia ClinVar NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449 		JBrowse link
acute monocytic leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnmt3a DNA methyltransferase 3 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:21399634 NCBI chr 6:28,205,375...28,346,052
Ensembl chr 6:28,235,695...28,340,577 		JBrowse link
G Kmt2a lysine methyltransferase 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:8282816 NCBI chr 8:49,110,407...49,185,872
Ensembl chr 8:49,114,990...49,158,971 		JBrowse link
G Mllt10 MLLT10, histone lysine methyltransferase DOT1L cofactor ISO RGD PMID:7662954 RGD:1598771 NCBI chr17:84,847,660...84,981,134
Ensembl chr17:84,881,414...84,979,543 		JBrowse link
G Nf1 neurofibromin 1 ISO ClinVar Annotator: match by term: Acute monocytic leukemia ClinVar PMID:23407919 PMID:25741868 PMID:28492532 NCBI chr10:66,732,460...66,928,706
Ensembl chr10:66,690,133...66,928,903 		JBrowse link
G Stk11 serine/threonine kinase 11 ISO ClinVar Annotator: match by term: Acute monocytic leukemia ClinVar PMID:25117502 PMID:25741868 PMID:25980754 PMID:26467025 PMID:28492532 NCBI chr 7:12,440,751...12,457,513
Ensembl chr 7:12,440,751...12,457,513 		JBrowse link
acute myeloid leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc3 ATP binding cassette subfamily C member 3 disease_progression ISO RGD PMID:26512967 RGD:11081145 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 disease_progression
treatment		 ISO RGD PMID:26512967, PMID:12145683 RGD:11081145, RGD:11099971 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621 		JBrowse link
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase ISO DNA:translocation: : RGD PMID:12161353 RGD:10450603 NCBI chr 3:10,041,820...10,145,076
Ensembl chr 3:10,041,826...10,144,388 		JBrowse link
G Acsl6 acyl-CoA synthetase long-chain family member 6 ISO DNA:translocation: :t(5;12)(q31;p13) (human) RGD PMID:10502316 RGD:1599805 NCBI chr10:39,654,771...39,717,592
Ensembl chr10:39,655,455...39,719,312 		JBrowse link
G Adcy7 adenylate cyclase 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18206229 NCBI chr19:19,702,307...19,762,973
Ensembl chr19:19,704,859...19,727,081 		JBrowse link
G Agrn agrin ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 5:173,589,910...173,622,813
Ensembl chr 5:173,589,819...173,622,645 		JBrowse link
G Alk ALK receptor tyrosine kinase ISO ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:25741868 PMID:28492532 NCBI chr 6:22,696,415...23,203,791
Ensembl chr 6:22,696,397...23,203,775 		JBrowse link
G Anapc2 anaphase promoting complex subunit 2 ISO mRNA:increased expression:blood (human) RGD PMID:26046517 RGD:11067888 NCBI chr 3:2,490,496...2,502,247
Ensembl chr 3:2,490,518...2,502,248 		JBrowse link
G Anxa2 annexin A2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 8:75,687,134...75,723,589
Ensembl chr 8:75,687,100...75,723,594 		JBrowse link
G Anxa4 annexin A4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 4:118,538,775...118,595,591
Ensembl chr 4:118,538,777...118,595,580 		JBrowse link
G Anxa5 annexin A5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 2:123,162,477...123,194,730
Ensembl chr 2:123,162,461...123,193,130 		JBrowse link
G Anxa6 annexin A6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr10:40,320,581...40,375,605
Ensembl chr10:40,320,581...40,375,605 		JBrowse link
G Aqp9 aquaporin 9 ISO CTD Direct Evidence: therapeutic CTD PMID:16968895 NCBI chr 8:77,559,621...77,599,781
Ensembl chr 8:77,559,624...77,599,781 		JBrowse link
G Arid4a AT-rich interaction domain 4A ISS OMIM:601626 MouseDO NCBI chr 6:93,461,713...93,532,901
Ensembl chr 6:93,461,713...93,532,901 		JBrowse link
G Asmtl acetylserotonin O-methyltransferase-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr12:18,532,090...18,534,761
Ensembl chr12:18,531,990...18,534,836 		JBrowse link
G Asxl1 ASXL transcriptional regulator 1 disease_progression ISO
ISS		 DNA:mutations:exon:
OMIM:601626		 MouseDO PMID:20693432 RGD:11038706 NCBI chr 3:148,832,231...148,902,356
Ensembl chr 3:148,837,814...148,900,452 		JBrowse link
G Asxl2 ASXL transcriptional regulator 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27798625 NCBI chr 6:27,835,346...27,919,285
Ensembl chr 6:27,887,797...27,915,563 		JBrowse link
G Atg2b autophagy related 2B ISO ClinVar Annotator: match by term: Leukemia, acute myeloid ClinVar NCBI chr 6:129,449,451...129,519,599
Ensembl chr 6:129,449,449...129,509,720 		JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr13:82,737,161...82,757,681
Ensembl chr13:82,737,159...82,758,004 		JBrowse link
G Baalc BAALC binder of MAP3K1 and KLF4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19822134 NCBI chr 7:77,761,056...77,836,534
Ensembl chr 7:77,763,512...77,837,453 		JBrowse link
G Bach2 BTB domain and CNC homolog 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21441929 NCBI chr 5:47,458,891...47,807,176
Ensembl chr 5:47,546,014...47,807,166 		JBrowse link
G Bcl2 BCL2, apoptosis regulator susceptibility
severity		 ISO DNA:snp:promoter:g.-938C>A (human)
CTD Direct Evidence: marker/mechanism
DNA:snp:exon:c.+21A>G (rs1801018) (human)
ratio with Flt3, Kit;mRNA:decreased expression:mononuclear cell (human)		 CTD PMID:23906301, PMID:25957891, PMID:19520430, PMID:25216797 RGD:11526107, RGD:11526111, RGD:11526109 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374 		JBrowse link
G Bcl2l1 Bcl2-like 1 severity ISO mRNA:increased expression:peripheral blood, bone marrow, blast cell (human) RGD PMID:11410409 RGD:11353851 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810 		JBrowse link
G Bdkrb1 bradykinin receptor B1 ISO ClinVar Annotator: match by term: Leukemia, acute myeloid ClinVar NCBI chr 6:129,437,423...129,441,553
Ensembl chr 6:129,438,158...129,440,574 		JBrowse link
G Bdkrb2 bradykinin receptor B2 ISO ClinVar Annotator: match by term: Leukemia, acute myeloid ClinVar NCBI chr 6:129,399,468...129,429,676
Ensembl chr 6:129,399,468...129,429,676 		JBrowse link
G Bmi1 BMI1 proto-oncogene, polycomb ring finger ISO RGD PMID:16105758 RGD:1580059 NCBI chr17:85,360,439...85,370,283
Ensembl chr17:85,364,483...85,368,208 		JBrowse link
G Brca2 BRCA2, DNA repair associated ISO ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:15766593 PMID:25741868 PMID:26467025 PMID:28492532 PMID:29021639 NCBI chr12:503,660...544,754
Ensembl chr12:504,007...544,748 		JBrowse link
G Brd4 bromodomain containing 4 ISO RGD PMID:21814200 RGD:9586350 NCBI chr 7:14,222,101...14,303,055
Ensembl chr 7:14,222,101...14,303,055 		JBrowse link
G Brd7 bromodomain containing 7 susceptibility ISO mRNA:increased expression:bone marrow:
DNA:haplotype:cds:737A>G,495C>T(human)		 RGD PMID:18772500, PMID:18772500 RGD:9586443, RGD:9586443 NCBI chr19:19,672,780...19,701,484
Ensembl chr19:19,672,856...19,701,484 		JBrowse link
G Btg1 BTG anti-proliferation factor 1 disease_progression ISO RGD PMID:15449376 RGD:1549463 NCBI chr 7:37,812,831...37,815,088
Ensembl chr 7:37,812,831...37,815,088 		JBrowse link
G Calr calreticulin ISO mRNA:increased expression:peripheral blood (human) RGD PMID:26640226 RGD:11076986 NCBI chr19:25,956,771...25,961,666
Ensembl chr19:25,956,771...25,961,666 		JBrowse link
G Capg capping actin protein, gelsolin like ISO CTD Direct Evidence: marker/mechanism CTD PMID:18206229 NCBI chr 4:100,395,693...100,419,447
Ensembl chr 4:100,407,658...100,419,446 		JBrowse link
G Capn2 calpain 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr13:100,878,649...100,928,811
Ensembl chr13:100,878,650...100,928,811 		JBrowse link
G Casp7 caspase 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774 		JBrowse link
G Cbfb core-binding factor subunit beta ISO ClinVar Annotator: match by term: Acute myeloid leukemia
CTD Direct Evidence: marker/mechanism		 OMIM
ClinVar
CTD		 PMID:18206229 PMID:25741868 PMID:27798625 NCBI chr19:37,127,508...37,171,075
Ensembl chr19:37,127,508...37,171,069 		JBrowse link
G Cbl Cbl proto-oncogene disease_progression ISO associated with Myelodysplastic Syndromes;DNA:mutations:exons: RGD PMID:22131879 RGD:11038796 NCBI chr 8:48,481,256...48,564,775
Ensembl chr 8:48,489,036...48,564,722 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 treatment ISO protein:increased expression:plasma (human) RGD PMID:25382729, PMID:17822317 RGD:11528532, RGD:11528537 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870 		JBrowse link
G Ccna1 cyclin A1 ISO protein:increased expression:leukocyte (human) RGD PMID:10068680 RGD:2316304 NCBI chr 2:144,456,689...144,503,570
Ensembl chr 2:144,458,153...144,467,912 		JBrowse link
G Ccnd1 cyclin D1 treatment ISO mRNA:increased expression:bone marrow (human)
human tumor in a mouse model		 RGD PMID:22391157, PMID:21928377 RGD:11352824, RGD:11353789 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325 		JBrowse link
G Ccnd2 cyclin D2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27798625 NCBI chr 4:159,674,885...159,697,207
Ensembl chr 4:159,674,885...159,697,207 		JBrowse link
G Cd33 CD33 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:12921496 NCBI chr 1:98,388,811...98,403,539
Ensembl chr 1:98,398,660...98,402,968 		JBrowse link
G Cd44 CD44 molecule (Indian blood group) ISO CTD Direct Evidence: marker/mechanism CTD PMID:23098472 NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658 		JBrowse link
G Cd86 CD86 molecule severity ISO protein:increased expression:mononuclear cell of bone marrow (human) RGD PMID:19197726, PMID:16115907 RGD:4892295, RGD:11354960 NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795 		JBrowse link
G Cd9 CD9 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 4:157,977,163...158,010,091
Ensembl chr 4:157,977,162...158,010,166 		JBrowse link
G Cdh1 cadherin 1 disease_progression ISO DNA:hypermethylation:promoter: RGD PMID:15863205 RGD:11252161 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395 		JBrowse link
G Cdk6 cyclin-dependent kinase 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18206229 NCBI chr 4:27,781,728...27,969,653
Ensembl chr 4:27,785,647...27,966,398 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B ISO DNA:deletion: : RGD PMID:9171997 RGD:10450601 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A disease_progression ISO DNA:deletion: :
mRNA,protein:altered expression:bone marrow:		 RGD PMID:11064355, PMID:11697625 RGD:11251749, RGD:11252080 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175 		JBrowse link
G Cdkn2a_v1 cyclin-dependent kinase inhibitor 2A, variant 1 ISO mRNA,protein:altered expression:bone marrow: RGD PMID:11697625 RGD:11252080
G Cdkn2a_v2 cyclin-dependent kinase inhibitor 2A, variant 2 ISO mRNA,protein:altered expression:bone marrow: RGD PMID:11697625 RGD:11252080
G Cdkn2b cyclin-dependent kinase inhibitor 2B susceptibility
treatment
disease_progression		 ISO DNA:hypermethylation: :
mRNA:decreased expression:granulocyte,monocyte:
DNA:hypermethylation:promoter:
DNA:deletion: :		 RGD PMID:25616284, PMID:9001419, PMID:14681685, PMID:27168825, PMID:15863205, PMID:11064355 RGD:11251739, RGD:11252196, RGD:11252167, RGD:11252164, RGD:11252161, RGD:11251749 NCBI chr 5:107,834,353...107,857,428
Ensembl chr 5:107,845,951...107,858,104 		JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha ISO ClinVar Annotator: match by term: Acute myeloid leukemia
ClinVar Annotator: match by term: Acute myelogenous leukemia
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: AML - Acute myeloid leukemia
ClinVar Annotator: match by OMIM:601626		 OMIM
ClinVar
CTD		 PMID:11242107 PMID:12661007 PMID:12692518 PMID:14726504 PMID:15575056 PMID:18768433 PMID:18987666 PMID:19731081 PMID:19822134 PMID:23926458 PMID:24220272 PMID:24728327 PMID:25741868 PMID:26162409 PMID:26721895 PMID:27005833 PMID:28250006 PMID:28492532 PMID:29296967 PMID:30420649 NCBI chr 1:91,363,492...91,366,164
Ensembl chr 1:91,363,492...91,366,164 		JBrowse link
G Cebpd CCAAT/enhancer binding protein delta ISO CTD Direct Evidence: marker/mechanism CTD PMID:17234736 NCBI chr11:89,008,008...89,009,146
Ensembl chr11:89,008,008...89,009,146 		JBrowse link
G Cfhr1 complement factor H-related 1 susceptibility ISO DNA:deletion: : RGD PMID:26317246 RGD:11341662 NCBI chr13:56,862,666...56,877,650
Ensembl chr13:56,836,994...56,877,650 		JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator disease_progression ISO RGD PMID:23167276 RGD:11341679 NCBI chr 9:65,534,608...65,586,395
Ensembl chr 9:65,534,704...65,587,251 		JBrowse link
G Chi3l1 chitinase 3 like 1 severity ISO protein:increased secretion:serum (human) RGD PMID:16361549 RGD:4892644 NCBI chr13:51,022,844...51,030,797
Ensembl chr13:51,022,681...51,030,802 		JBrowse link
G Chic2 cysteine-rich hydrophobic domain 2 ISO OMIM NCBI chr14:35,683,657...35,718,005
Ensembl chr14:35,683,442...35,717,922 		JBrowse link
G Chmp5 charged multivesicular body protein 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17708794 NCBI chr 5:57,267,312...57,284,455
Ensembl chr 5:57,267,312...57,284,448 		JBrowse link
G Cnr2 cannabinoid receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15039279 NCBI chr 5:154,242,010...154,268,126
Ensembl chr 5:154,260,062...154,268,126 		JBrowse link
G Crebbp CREB binding protein ISO
ISS		 DNA:translocations:intron:IVS2 (human)
OMIM:601626		 MouseDO PMID:12461753 RGD:734819 NCBI chr10:11,590,994...11,721,039
Ensembl chr10:11,595,044...11,721,039 		JBrowse link
G Csf1r colony stimulating factor 1 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:1390197 NCBI chr18:56,414,493...56,458,300
Ensembl chr18:56,414,488...56,458,300 		JBrowse link
G Csf2 colony stimulating factor 2 treatment ISO CTD Direct Evidence: marker/mechanism CTD PMID:21441929, PMID:1826536 RGD:10449528 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070 		JBrowse link
G Csf3 colony stimulating factor 3 treatment ISO CTD Direct Evidence: therapeutic CTD PMID:7528855, PMID:10673519 RGD:11039033 NCBI chr10:86,616,785...86,619,160
Ensembl chr10:86,616,785...86,619,157 		JBrowse link
G Csf3r colony stimulating factor 3 receptor disease_progression
susceptibility		 ISO ClinVar Annotator: match by term: Acute myelocytic leukemia
associated with Severe Congenital Neutropenia;DNA:nonsense mutation:cds:		 ClinVar PMID:23604229 PMID:23634996 PMID:23656643 PMID:24081659 PMID:24403076 PMID:24614839 PMID:24854193 PMID:25491280 PMID:25741868 PMID:25932451 PMID:26875968 PMID:27148573 PMID:27581359 PMID:28209919 PMID:28219221 PMID:28492532 PMID:28762112 PMID:30967555, PMID:24746896, PMID:9001427, PMID:21911095 RGD:10450468, RGD:10450487, RGD:10450470 NCBI chr 5:144,031,353...144,051,966
Ensembl chr 5:144,031,402...144,051,600 		JBrowse link
G Cst3 cystatin C ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 3:143,219,671...143,223,544
Ensembl chr 3:143,219,686...143,223,615 		JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 ISO DNA:SNP:3'UTR:rs3087243(human) RGD PMID:19092854 RGD:11344911 NCBI chr 9:67,699,397...67,706,068
Ensembl chr 9:67,699,379...67,706,065 		JBrowse link
G Ctnna1 catenin alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr18:27,923,229...28,055,972
Ensembl chr18:27,923,572...28,055,960 		JBrowse link
G Ctsh cathepsin H ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 8:97,439,155...97,458,293
Ensembl chr 8:97,439,161...97,458,287 		JBrowse link
G Ctsz cathepsin Z ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 3:172,527,107...172,537,877
Ensembl chr 3:172,527,107...172,537,877 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 treatment
disease_progression		 ISO RGD PMID:26031918, PMID:24035716 RGD:11352265, RGD:11352273 NCBI chr13:45,314,952...45,318,856
Ensembl chr13:45,314,933...45,318,878 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 disease_progression
no_association		 ISO DNA:SNP: :6235T>C (human)
DNA:polymorphism: :6235T>C (human)
DNA:SNP: :4889A>G (human)		 RGD PMID:19456854, PMID:15996939, PMID:19456854 RGD:10769358, RGD:11352736, RGD:10769358 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 susceptibility ISO DNA:polymorphism:G15631T RGD PMID:19144407 RGD:6480472 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 susceptibility
treatment		 ISO DNA:polymorphisms: :
DNA:SNP: :(rs16947)(human)		 RGD PMID:11037802, PMID:21518482 RGD:11352820, RGD:11352828 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436 		JBrowse link
G Dapk1 death associated protein kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19874806 NCBI chr17:4,297,038...4,454,941
Ensembl chr17:4,297,224...4,454,778 		JBrowse link
G Ddx41 DEAD-box helicase 41 ISO ClinVar Annotator: match by term: Leukemia, acute myeloid
ClinVar Annotator: match by term: Acute myeloid leukemia		 ClinVar PMID:25741868 PMID:25920683 PMID:26712909 NCBI chr17:9,631,925...9,637,317
Ensembl chr17:9,631,925...9,637,316 		JBrowse link
G Dhx15 DEAH-box helicase 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27798625 PMID:29163777 NCBI chr14:61,136,740...61,174,880
Ensembl chr14:61,136,746...61,174,880 		JBrowse link
G Dlec1 DLEC1 cilia and flagella associated protein treatment ISO DNA:hypermethylation:promoter: RGD PMID:27168825 RGD:11252164 NCBI chr 8:127,788,919...127,835,986
Ensembl chr 8:127,789,048...127,834,637 		JBrowse link
G Dnmt1 DNA methyltransferase 1 ISO mRNA:increased expression:CD34+ bone marrow cells RGD PMID:11222358 RGD:9588667 NCBI chr 8:21,922,515...21,968,495
Ensembl chr 8:21,922,515...21,968,495 		JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha disease_progression
susceptibility
treatment		 ISO mRNA:increased expression:CD34+ bone marrow cells
ClinVar Annotator: match by term: Acute myeloid leukemia
DNA:missense mutation:exon:p.R882 (human)
associated with Myelodysplastic Syndromes; DNA:mutations:cds:
DNA:hypomethylation: :
DNA:mutation::		 ClinVar
OMIM		 PMID:21067377 PMID:21518476 PMID:22160010 PMID:22722925 PMID:22744846 PMID:22898539 PMID:22898540 PMID:22898541 PMID:24606448 PMID:24622842 PMID:24656771 PMID:25741868 PMID:26619011 PMID:26876596 PMID:27991732 PMID:28432085 PMID:28492532 PMID:28941052 PMID:32581362, PMID:11222358, PMID:24512939, PMID:21415852, PMID:26242829, PMID:25609058, PMID:22291079 RGD:9588667, RGD:11041123, RGD:11041122, RGD:11041121, RGD:11041120, RGD:9589067 NCBI chr 6:28,205,375...28,346,052
Ensembl chr 6:28,235,695...28,340,577 		JBrowse link
G Dnmt3b DNA methyltransferase 3 beta susceptibility
disease_progression		 ISO mRNA:increased expression:CD34+ bone marrow cells
DNA:SNP:promoter: C>T46359(human)
DNA:SNPs,haplotype: :rs1569686,rs2424908, rs6087990, rs6119954(human)		 RGD PMID:11222358, PMID:16194411, PMID:24069326, PMID:23251566 RGD:9588667, RGD:9589108, RGD:9589103, RGD:9589071 NCBI chr 3:149,131,541...149,170,061
Ensembl chr 3:149,131,785...149,208,786 		JBrowse link
G Ehd3 EH-domain containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 6:25,076,012...25,102,457
Ensembl chr 6:25,074,955...25,100,977 		JBrowse link
G Ehmt2 euchromatic histone lysine methyltransferase 2 disease_progression ISO CTD Direct Evidence: marker/mechanism CTD PMID:24532712, PMID:24532712 RGD:9589168 NCBI chr20:4,576,033...4,592,980
Ensembl chr20:4,576,057...4,592,980 		JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19458359 NCBI chr16:68,954,860...68,968,248
Ensembl chr16:68,954,875...68,968,248 		JBrowse link
G Enah ENAH, actin regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:26237430 NCBI chr13:100,297,421...100,415,335
Ensembl chr13:100,300,054...100,414,226 		JBrowse link
G Eno2 enolase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 4:157,285,192...157,294,090
Ensembl chr 4:157,285,179...157,294,047 		JBrowse link
G Ephx1 epoxide hydrolase 1 no_association ISO DNA:SNPs:exon:rs1051740, rs2234922 (human)
CTD Direct Evidence: marker/mechanism
DNA:missense mutations:exon:p.Y113H, p.H139R (human)
DNA:polymorphism		 CTD PMID:29605894, PMID:22200898, PMID:11849215, PMID:20731606 RGD:11252114, RGD:11252119, RGD:11252115 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579 		JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit treatment
no_association		 ISO DNA:polymorphism: :p.R399Q (human)
DNA:SNP: :p.Q504K (human)		 RGD PMID:18604718, PMID:23397959, PMID:16507781, PMID:20141440, PMID:21942242 RGD:11252170, RGD:11252193, RGD:11252179, RGD:11252173, RGD:11252171 NCBI chr 1:80,256,973...80,268,198
Ensembl chr 1:80,256,973...80,268,198 		JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit disease_progression
no_association		 ISO DNA:polymorphism: :p.K751Q (rs13181) (human)
DNA:SNPs, haplotypes: :p.D312N, p.K751Q (human)
associated with Myeloproliferative Disorders;DNA:polymorphism: :p.K751Q (rs13181) (human)		 RGD PMID:20141440, PMID:21394217, PMID:22496165, PMID:23397959 RGD:11252173, RGD:11252209, RGD:11252198, RGD:11252193 NCBI chr 1:80,293,574...80,307,334
Ensembl chr 1:80,293,566...80,307,344 		JBrowse link
G Erg ETS transcription factor ERG ISO CTD Direct Evidence: marker/mechanism CTD PMID:19822134 NCBI chr11:35,645,317...35,749,637
Ensembl chr11:35,646,116...35,749,594 		JBrowse link
G Etv6 ETS variant transcription factor 6 ISO ClinVar Annotator: match by term: Acute myeloid leukemia
DNA:translocation: :
DNA:deletion: :
DNA:translocation: :t(5;12)(q31;p13) (human)
ClinVar Annotator: match by term: Leukemia, acute myeloid, UMLS MESH term: Acute Myelogenous Leukemia		 OMIM
ClinVar		 PMID:15806161 PMID:25581430 PMID:25807284 PMID:31248877, PMID:12161353, PMID:9171997, PMID:10502316 RGD:10450603, RGD:10450601, RGD:1599805 NCBI chr 4:167,754,684...167,992,370
Ensembl chr 4:167,754,525...167,992,168 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit disease_progression
susceptibility		 ISO mRNA:increased expression:bone marrow, mononuclear cell (human)
DNA:mutations:cds:multiple (human)		 RGD PMID:22677129, PMID:21125401, PMID:23099237 RGD:10450874, RGD:10450887, RGD:10450876 NCBI chr 4:77,284,404...77,347,011
Ensembl chr 4:77,284,404...77,347,011 		JBrowse link
G F3 coagulation factor III, tissue factor ISO RGD PMID:2617479 RGD:11340207 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272 		JBrowse link
G Fadd Fas associated via death domain disease_progression ISO RGD PMID:15520222 RGD:11341799 NCBI chr 1:217,746,176...217,748,581
Ensembl chr 1:217,742,929...217,748,628 		JBrowse link
G Fanca FA complementation group A ISO DNA, mRNA:deletions, decreased expression: :multiple RGD PMID:14749703 RGD:11344889 NCBI chr19:56,067,548...56,126,075
Ensembl chr19:56,067,548...56,126,063 		JBrowse link
G Fancc FA complementation group C susceptibility ISO DNA:polymorphism:cds:p.S26F (human) RGD PMID:12670332 RGD:11046259 NCBI chr17:826,512...955,703
Ensembl chr17:833,509...955,615 		JBrowse link
G Fas Fas cell surface death receptor susceptibility ISO DNA:polymorphism, haplotype:promoter:-1377 G>A, -670 G>A (human)
CTD Direct Evidence: marker/mechanism		 CTD PMID:7579353, PMID:12907599, PMID:8870373 RGD:11049150, RGD:11049452 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790 		JBrowse link
G Fermt2 FERM domain containing kindlin 2 disease_progression ISO RGD PMID:22391155 RGD:11352307 NCBI chr15:19,807,806...19,876,557
Ensembl chr15:19,807,808...19,876,408 		JBrowse link
G Fermt3 FERM domain containing kindlin 3 disease_progression ISO RGD PMID:22391155 RGD:11352307 NCBI chr 1:222,254,183...222,272,775
Ensembl chr 1:222,254,184...222,272,285 		JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 treatment ISO RGD PMID:27005999, PMID:23777766, PMID:22683780 RGD:11352310, RGD:11352670, RGD:11352665 NCBI chr16:71,265,390...71,319,046
Ensembl chr16:71,266,248...71,319,449 		JBrowse link
G Fhl2 four and a half LIM domains 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 9:49,920,611...49,994,906
Ensembl chr 9:49,920,854...49,950,093 		JBrowse link
G Flt3 Fms related receptor tyrosine kinase 3 treatment
disease_progression		 ISO ClinVar Annotator: match by term: Leukemia, acute myeloid, reduced survival in, somatic
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Leukemia, acute myelogenous
ClinVar Annotator: match by term: Acute myeloid leukemia
DNA:missense mutation:exon:p.D835Y,D835H(human)
DNA:mutations:cds:
DNA:duplication mutation:cds:
mRNA,protein:increased expression:bone marrow:
ClinVar Annotator: match by term: Leukemia, acute myeloid, UMLS MESH term: Acute Myelogenous Leukemia		 ClinVar
CTD
OMIM		 PMID:11091200 PMID:11290608 PMID:11442493 PMID:12384447 PMID:14604974 PMID:14670924 PMID:14737077 PMID:15256420 PMID:15374878 PMID:15625552 PMID:15667533 PMID:15863200 PMID:16091740 PMID:16371029 PMID:16410449 PMID:16573742 PMID:16857985 PMID:16990784 PMID:17047150 PMID:17050201 PMID:17184839 PMID:17387224 PMID:17606455 PMID:17889720 PMID:17942876 PMID:19602710 PMID:19657110 PMID:19822134 PMID:19840437 PMID:20733134 PMID:21441929 PMID:21482694 PMID:21928377 PMID:22368270 PMID:22409268 PMID:22504183 PMID:22504184 PMID:22504185 PMID:22504186 PMID:23036488 PMID:23261068 PMID:23321257 PMID:23430109 PMID:23714533 PMID:23783394 PMID:23878140 PMID:23906301 PMID:24046014 PMID:24526162 PMID:24619500 PMID:25053825 PMID:25157968 PMID:27099147 PMID:27992414, PMID:11290608, PMID:11442493, PMID:23969938, PMID:24184354, PMID:16642044, PMID:8562934 RGD:1598955, RGD:11049497, RGD:11049482, RGD:11049471, RGD:11049467, RGD:11049466 NCBI chr12:9,360,439...9,437,004
Ensembl chr12:9,360,672...9,436,570 		JBrowse link
G Foxo1 forkhead box O1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 2:141,451,234...141,527,016
Ensembl chr 2:141,451,234...141,527,016 		JBrowse link
G Fxyd6 FXYD domain-containing ion transport regulator 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 8:49,676,520...49,703,419
Ensembl chr 8:49,676,540...49,703,419 		JBrowse link
G Gas2l1 growth arrest-specific 2 like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr14:85,308,443...85,318,475
Ensembl chr14:85,308,443...85,318,194 		JBrowse link
G Gata1 GATA binding protein 1 disease_progression ISO RGD PMID:7579412 RGD:10450754 NCBI chr  X:15,273,937...15,281,759
Ensembl chr  X:15,378,789...15,382,066 		JBrowse link
G Gata2 GATA binding protein 2 disease_progression ISO ClinVar Annotator: match by term: Leukemia, acute myeloid, susceptibility to
ClinVar Annotator: match by term: Acute myeloid leukemia
CTD Direct Evidence: marker/mechanism
mRNA:decreased expression:CD34+ bone marrow cell:		 OMIM
ClinVar
CTD		 PMID:20040766 PMID:21242295 PMID:21670465 PMID:21765025 PMID:21892158 PMID:21892162 PMID:22147895 PMID:23365458 PMID:25676417 PMID:25741868 PMID:28492532, PMID:22786876, PMID:24514424, PMID:25241285 RGD:11049515, RGD:11049514, RGD:11049510 NCBI chr 4:120,129,028...120,142,490
Ensembl chr 4:120,133,713...120,142,488 		JBrowse link
G Gfi1 growth factor independent 1 transcriptional repressor susceptibility ISO DNA:SNP:cds:c.107G>A(rs34631763)(human)
CTD Direct Evidence: marker/mechanism		 CTD PMID:17330099, PMID:20075157 RGD:11040450 NCBI chr14:3,058,035...3,073,332
Ensembl chr14:3,058,993...3,068,371 		JBrowse link
G Gfi1b growth factor independent 1B transcriptional repressor ISO mRNA:increased expression:bone marrow cell: RGD PMID:17156408 RGD:11040507 NCBI chr 3:7,190,721...7,203,444
Ensembl chr 3:7,190,722...7,203,420 		JBrowse link
G Gpi glucose-6-phosphate isomerase ISO protein:increased expression:plasma: RGD PMID:6589021 RGD:11051848 NCBI chr 1:90,063,411...90,091,287
Ensembl chr 1:90,063,411...90,091,287 		JBrowse link
G Gpx1 glutathione peroxidase 1 disease_progression
treatment
susceptibility		 ISO DNA:SNP: :c.599C>T (rs1050450) (human)
DNA:polymorphism: :p.P198L (human)		 RGD PMID:26950655, PMID:22930375, PMID:26823947 RGD:11061784, RGD:11352817, RGD:11061561 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522 		JBrowse link
G Gskip GSK3B interacting protein ISO ClinVar Annotator: match by term: Leukemia, acute myeloid ClinVar NCBI chr 6:129,512,950...129,536,320
Ensembl chr 6:129,519,709...129,536,221 		JBrowse link
G Gsr glutathione-disulfide reductase ISO RGD PMID:24191316 RGD:11059506 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 susceptibility
disease_progression		 ISO DNA:methylation: :
DNA:deletion: : (human)		 RGD PMID:11488937, PMID:22924777, PMID:18035413 RGD:10450822, RGD:10755405, RGD:10755318 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 susceptibility ISO chemotherapy-induced;
DNA:polymorphism:cds:p.I105V(human)		 RGD PMID:11553769, PMID:11906705, PMID:21729529 RGD:10755420, RGD:10755328, RGD:10755422 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147 		JBrowse link
G Gstt1 glutathione S-transferase theta 1 no_association
disease_progression
susceptibility		 ISO RGD PMID:9164324, PMID:18035413, PMID:11488937 RGD:10450779, RGD:10755318, RGD:10450822 NCBI chr20:13,799,102...13,816,527
Ensembl chr20:13,799,102...13,816,526 		JBrowse link
G Gtf2i general transcription factor II I ISO CTD Direct Evidence: marker/mechanism CTD PMID:18206229 NCBI chr12:25,410,804...25,487,970
Ensembl chr12:25,411,207...25,488,156 		JBrowse link
G H1f0 H1.0 linker histone ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 7:120,260,776...120,262,636 JBrowse link
G H1f2 H1.2 linker histone, cluster member ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr17:43,638,938...43,640,445
Ensembl chr17:43,639,749...43,640,387 		JBrowse link
G Hgf hepatocyte growth factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:22683780 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362 		JBrowse link
G Hmox1 heme oxygenase 1 IEP mRNA:increased expression:brain, spleen RGD PMID:19268504 RGD:10755700 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456 		JBrowse link
G Hoxa9 homeobox A9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22541086
G Hras HRas proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Leukemia, acute myelogenous
ClinVar Annotator: match by term: Acute myelogenous leukemia
ClinVar Annotator: match by term: Acute myelocytic leukemia
ClinVar Annotator: match by term: Acute myeloid leukemia		 ClinVar PMID:11150980 PMID:12835555 PMID:16155195 PMID:16170316 PMID:16329078 PMID:16372351 PMID:16443854 PMID:16835863 PMID:16881968 PMID:16969868 PMID:17054105 PMID:17211612 PMID:17384584 PMID:17412879 PMID:17979197 PMID:18039947 PMID:18042262 PMID:18247425 PMID:18978862 PMID:19206176 PMID:19213030 PMID:19255327 PMID:19371735 PMID:19382114 PMID:19669404 PMID:19773371 PMID:20660566 PMID:20859122 PMID:20979192 PMID:21438134 PMID:21495179 PMID:21686750 PMID:21834037 PMID:21850009 PMID:22087699 PMID:22256804 PMID:22317973 PMID:22495892 PMID:22499344 PMID:22683711 PMID:22726224 PMID:22926243 PMID:23093928 PMID:23096712 PMID:23406027 PMID:23429430 PMID:23751039 PMID:23884457 PMID:24006476 PMID:24033266 PMID:24129065 PMID:24169525 PMID:24224811 PMID:24390138 PMID:24803665 PMID:25157968 PMID:25326635 PMID:25741868 PMID:25914166 PMID:26619011 PMID:27195699 PMID:27589201 PMID:28027064 PMID:28139825 PMID:28492532 PMID:29493581 PMID:31394527 PMID:31775759 PMID:168335863 NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr12:23,839,390...23,841,051
Ensembl chr12:23,839,399...23,841,049 		JBrowse link
G Id2 inhibitor of DNA binding 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 6:44,360,077...44,361,908
Ensembl chr 6:44,348,501...44,363,915 		JBrowse link
G Idh1 isocitrate dehydrogenase (NADP(+)) 1 disease_progression ISO DNA:mutation:cds:p.R132(human)
ClinVar Annotator: match by term: Acute myelocytic leukemia
ClinVar Annotator: match by term: Acute myelogenous leukemia
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Leukemia, acute myelogenous
ClinVar Annotator: match by term: Acute myeloid leukemia
DNA:SNP::105C>T (rs11554137)(human)		 ClinVar
CTD		 PMID:18772396 PMID:19657110 PMID:19798509 PMID:19818334 PMID:20946881 PMID:21352804 PMID:21446021 PMID:22160010 PMID:22397365 PMID:22417203 PMID:22898539 PMID:23558169 PMID:24606448 PMID:25043048 PMID:25157968 PMID:25324972 PMID:25741868 PMID:26619011 PMID:27992414, PMID:20368543, PMID:25324972 RGD:11522718, RGD:11522721 NCBI chr 9:71,882,108...71,911,645
Ensembl chr 9:71,882,105...71,900,044 		JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 disease_progression ISO DNA:mutation:cds:p.R172(human)
ClinVar Annotator: match by term: Acute myelogenous leukemia
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Acute myeloid leukemia
ClinVar Annotator: match by term: Leukemia, acute myelogenous
DNA:mutation:cds:p.R140 (human)		 ClinVar
CTD		 PMID:20171147 PMID:20847235 PMID:20946881 PMID:21250968 PMID:21596855 PMID:21889589 PMID:21997850 PMID:22160010 PMID:22397365 PMID:22417203 PMID:22616558 PMID:22898539 PMID:23558173 PMID:23815907 PMID:23949315 PMID:24049096 PMID:24606448 PMID:25157968 PMID:25324972 PMID:25326635 PMID:25398939 PMID:25741868 PMID:26619011 PMID:27992414 PMID:28492532, PMID:20368543, PMID:25324972 RGD:11522718, RGD:11522721 NCBI chr 1:141,874,354...141,893,674
Ensembl chr 1:141,866,283...141,893,705 		JBrowse link
G Ifi30 IFI30, lysosomal thiol reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr16:20,426,566...20,430,772
Ensembl chr16:20,426,566...20,430,752 		JBrowse link
G Il10 interleukin 10 disease_progression ISO RGD PMID:23357299 RGD:11046264 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392 		JBrowse link
G Il1a interleukin 1 alpha treatment ISO RGD PMID:2460157 RGD:11051965 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086 		JBrowse link
G Il4r interleukin 4 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:11918534 NCBI chr 1:196,942,343...196,967,221
Ensembl chr 1:196,942,364...196,967,220 		JBrowse link
G Il6 interleukin 6 disease_progression
treatment		 ISO human protein in a rat model RGD PMID:23357299, PMID:8892684 RGD:11046264, RGD:11062010 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807 		JBrowse link
G Inpp4b inositol polyphosphate-4-phosphatase type II B ISO CTD Direct Evidence: marker/mechanism CTD PMID:29415082 NCBI chr19:29,592,889...30,341,528
Ensembl chr19:29,597,905...29,968,424 		JBrowse link
G Insl6 insulin-like 6 ISO ClinVar Annotator: match by term: Leukemia, acute myeloid
ClinVar Annotator: match by term: Acute myelogenous leukemia		 ClinVar PMID:15781101 PMID:15793561 PMID:15858187 PMID:16081687 PMID:16247455 PMID:16293597 PMID:16325696 PMID:16603627 PMID:16707754 PMID:16709929 PMID:16762626 PMID:17989398 PMID:18256599 PMID:18394554 PMID:19036091 PMID:19287384 PMID:19293426 PMID:20339092 PMID:20631743 PMID:20703299 PMID:21120162 PMID:21689158 PMID:22041374 PMID:22422826 PMID:22571758 PMID:22818858 PMID:22829971 PMID:23115274 PMID:24404189 PMID:24986690 PMID:25043017 PMID:25157968 PMID:25671252 PMID:25741868 PMID:32581362 NCBI chr 1:247,473,292...247,476,827
Ensembl chr 1:247,473,292...247,476,827 		JBrowse link
G Itgav integrin subunit alpha V treatment ISO RGD PMID:23770013 RGD:10755448 NCBI chr 3:71,113,269...71,205,958
Ensembl chr 3:71,114,100...71,202,411 		JBrowse link
G Itgb3 integrin subunit beta 3 treatment ISO RGD PMID:23770013, PMID:23770013 RGD:10755448, RGD:10755448 NCBI chr10:92,667,869...92,783,413
Ensembl chr10:92,667,869...92,783,410 		JBrowse link
G Jak1 Janus kinase 1 ISO ClinVar Annotator: match by term: Leukemia, acute myelogenous ClinVar PMID:16239216 PMID:19139102 PMID:19470474 PMID:19838194 PMID:21436584 PMID:21680795 NCBI chr 5:119,982,503...120,091,452
Ensembl chr 5:119,982,943...120,083,904 		JBrowse link
G Jak2 Janus kinase 2 ISO ClinVar Annotator: match by term: Acute myelogenous leukemia
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Leukemia, acute myeloid, UMLS MESH term: Acute Myelogenous Leukemia		 OMIM
ClinVar
CTD		 PMID:15781101 PMID:15793561 PMID:15858187 PMID:16081687 PMID:16247455 PMID:16293597 PMID:16325696 PMID:16603627 PMID:16707754 PMID:16709929 PMID:16762626 PMID:17989398 PMID:18256599 PMID:18394554 PMID:19036091 PMID:19287384 PMID:19293426 PMID:20339092 PMID:20631743 PMID:20703299 PMID:21120162 PMID:21689158 PMID:22041374 PMID:22422826 PMID:22571758 PMID:22818858 PMID:22829971 PMID:23115274 PMID:24404189 PMID:24986690 PMID:25043017 PMID:25157968 PMID:25671252 PMID:25741868 PMID:32581362 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509 		JBrowse link
G Kat6a lysine acetyltransferase 6A ISO human gene in a mouse model;DNA:translocation:exon RGD PMID:12676584 RGD:9590334 NCBI chr16:73,942,669...74,020,750
Ensembl chr16:73,943,455...74,023,005 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase ISO ClinVar Annotator: match by term: Acute myelocytic leukemia
ClinVar Annotator: match by term: Acute myeloid leukemia		 OMIM
ClinVar		 PMID:7479840 PMID:7513208 PMID:7691885 PMID:8589724 PMID:9657776 PMID:9827716 PMID:9990072 PMID:11380399 PMID:11493470 PMID:15685537 PMID:15790786 PMID:15972446 PMID:16352739 PMID:16384925 PMID:16731599 PMID:16741525 PMID:16912224 PMID:17259998 PMID:17699867 PMID:18024392 PMID:18986703 PMID:19164557 PMID:19262599 PMID:19865100 PMID:21642685 PMID:21689725 PMID:22504184 PMID:22932406 PMID:23149070 PMID:23582185 PMID:23714533 PMID:24045550 PMID:25157968 PMID:25741868 PMID:26158763 PMID:26822237 PMID:27777718 PMID:28492532 NCBI chr14:35,072,131...35,149,638
Ensembl chr14:35,072,108...35,149,610 		JBrowse link
G Klf1 Kruppel like factor 1 disease_progression ISO RGD PMID:19097174 RGD:10769344 NCBI chr19:26,016,289...26,019,557
Ensembl chr19:26,016,382...26,019,553 		JBrowse link
G Kmt2a lysine methyltransferase 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:10339604 PMID:26237430, PMID:8361504 RGD:1625285 NCBI chr 8:49,110,407...49,185,872
Ensembl chr 8:49,114,990...49,158,971 		JBrowse link
G Kmt2b lysine methyltransferase 2B susceptibility ISO RGD PMID:25079327 RGD:9588599 NCBI chr 1:89,022,889...89,042,176
Ensembl chr 1:89,023,200...89,042,176 		JBrowse link
G Kmt2c lysine methyltransferase 2C ISO CTD Direct Evidence: marker/mechanism CTD PMID:24794707 NCBI chr 4:82,506...109,986
NCBI chr 4:6,083,650...6,294,413
Ensembl chr 4:6,083,736...6,292,516 		JBrowse link
G Kras KRAS proto-oncogene, GTPase ISO OMIM:601626
ClinVar Annotator: match by term: Acute myeloblastic leukemia
ClinVar Annotator: match by term: Acute myelogenous leukemia
ClinVar Annotator: match by term: Leukemia, acute myelogenous
ClinVar Annotator: match by term: Leukemia, acute myeloid, UMLS MESH term: Acute Myelogenous Leukemia		 ClinVar
OMIM		 PMID:2278970 PMID:2547513 PMID:3122217 PMID:3627975 PMID:7773929 PMID:8439212 PMID:8955068 PMID:12460918 PMID:15696205 PMID:15842656 PMID:16361624 PMID:16434492 PMID:16618717 PMID:17332249 PMID:17384584 PMID:17704260 PMID:17910045 PMID:18316791 PMID:18794081 PMID:19018267 PMID:19029981 PMID:19047918 PMID:19075190 PMID:19114683 PMID:19255327 PMID:19358724 PMID:19679400 PMID:19773371 PMID:19881948 PMID:20609353 PMID:20805368 PMID:20921462 PMID:20921465 PMID:20949522 PMID:20978259 PMID:21063026 PMID:21079152 PMID:21169357 PMID:21228335 PMID:21398618 PMID:21975775 PMID:22025163 PMID:22235099 PMID:22392911 PMID:22407852 PMID:22499344 PMID:22571758 PMID:22683711 PMID:22722830 PMID:22734028 PMID:22897852 PMID:23014527 PMID:23096712 PMID:23182985 PMID:23325582 PMID:23406027 PMID:24033266 PMID:24558511 PMID:24720724 PMID:25044103 PMID:25157968 PMID:25695684 PMID:25705018 PMID:25741868 PMID:25808193 PMID:26372703 PMID:26619011 PMID:26623049 PMID:28492532 PMID:29298116 PMID:31891627 PMID:32581362, PMID:8955068, PMID:21283084 RGD:1600469, RGD:11060151 NCBI chr 4:179,482,562...179,515,483
Ensembl chr 4:179,486,105...179,515,558 		JBrowse link
G LOC100909954 uncharacterized LOC100909954 ISO ClinVar Annotator: match by term: Leukemia, acute myeloid ClinVar NCBI chr 6:129,259,581...129,322,113 JBrowse link
G Lpar1 lysophosphatidic acid receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 5:75,557,038...75,678,067
Ensembl chr 5:75,557,042...75,676,584 		JBrowse link
G Lpp LIM domain containing preferred translocation partner in lipoma ISO OMIM NCBI chr11:79,192,603...79,827,858
Ensembl chr11:79,205,730...79,703,736 		JBrowse link
G Lrrc56 leucine rich repeat containing 56 ISO ClinVar Annotator: match by term: Leukemia, acute myelogenous
ClinVar Annotator: match by term: Acute myelogenous leukemia
ClinVar Annotator: match by term: Acute myelocytic leukemia		 ClinVar PMID:11150980 PMID:12835555 PMID:16155195 PMID:16170316 PMID:16329078 PMID:16372351 PMID:16443854 PMID:16835863 PMID:16881968 PMID:16969868 PMID:17054105 PMID:17211612 PMID:17384584 PMID:17412879 PMID:17979197 PMID:18039947 PMID:18042262 PMID:18247425 PMID:18978862 PMID:19206176 PMID:19213030 PMID:19255327 PMID:19371735 PMID:19382114 PMID:19669404 PMID:19773371 PMID:20660566 PMID:20859122 PMID:20979192 PMID:21438134 PMID:21495179 PMID:21686750 PMID:21834037 PMID:21850009 PMID:22087699 PMID:22256804 PMID:22317973 PMID:22495892 PMID:22499344 PMID:22683711 PMID:22726224 PMID:22926243 PMID:23093928 PMID:23096712 PMID:23406027 PMID:23429430 PMID:23751039 PMID:23884457 PMID:24006476 PMID:24033266 PMID:24129065 PMID:24169525 PMID:24224811 PMID:24390138 PMID:24803665 PMID:25157968 PMID:25326635 PMID:25741868 PMID:25914166 PMID:26619011 PMID:27195699 PMID:27589201 PMID:28027064 PMID:28139825 PMID:28492532 PMID:29493581 PMID:31394527 PMID:31775759 PMID:168335863 NCBI chr 1:214,182,232...214,197,184
Ensembl chr 1:214,182,830...214,197,184 		JBrowse link
G Lyl1 LYL1, basic helix-loop-helix family member ISO CTD Direct Evidence: marker/mechanism CTD PMID:16094422 NCBI chr19:25,815,207...25,818,074
Ensembl chr19:25,815,207...25,818,074 		JBrowse link
G Mdm2 MDM2 proto-oncogene disease_progression ISO RGD PMID:11064355 RGD:11251749 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328 		JBrowse link
G Mecom MDS1 and EVI1 complex locus ISO CTD Direct Evidence: marker/mechanism CTD PMID:30472098 NCBI chr 2:117,396,084...117,993,604
Ensembl chr 2:117,396,007...117,454,769 		JBrowse link
G Mefv MEFV innate immuity regulator, pyrin susceptibility ISO DNA:polymorphisms:cds:p.M694V,E148Q(human) RGD PMID:22351163 RGD:11531114 NCBI chr10:12,045,813...12,056,229
Ensembl chr10:12,046,541...12,056,311 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:22683780 NCBI chr 4:44,747,467...44,854,628
Ensembl chr 4:44,774,741...44,852,665 		JBrowse link
G Mir155 microRNA 155 ISO miRNA:increased expression:blood
miRNA:decreased expression:peripheral blood mononuclear cell		 RGD PMID:28989535, PMID:26923190 RGD:24922214, RGD:25671477 NCBI chr11:24,176,603...24,176,667
Ensembl chr11:24,176,603...24,176,667 		JBrowse link
G Mlf1 myeloid leukemia factor 1 ISO RGD PMID:15659732 RGD:1600902 NCBI chr 2:164,549,423...164,582,645
Ensembl chr 2:164,549,455...164,582,643 		JBrowse link
G Mllt10 MLLT10, histone lysine methyltransferase DOT1L cofactor ISO OMIM NCBI chr17:84,847,660...84,981,134
Ensembl chr17:84,881,414...84,979,543 		JBrowse link
G Mn1 MN1 proto-oncogene, transcriptional regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:19822134 NCBI chr12:51,214,192...51,250,230
Ensembl chr12:51,214,192...51,250,230 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO DNA:SNPs: :677C>T, 1298A>C(human) RGD PMID:17156840 RGD:10449408 NCBI chr 5:164,844,642...164,864,360
Ensembl chr 5:164,845,925...164,860,910 		JBrowse link
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase susceptibility ISO DNA:polymorphism: :66A>G(human) RGD PMID:18774170 RGD:11075096 NCBI chr 1:37,743,089...37,774,485
Ensembl chr 1:37,743,147...37,774,015 		JBrowse link
G Mx2 MX dynamin like GTPase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr11:38,035,306...38,066,185
Ensembl chr11:38,035,450...38,059,950 		JBrowse link
G Mybl2 MYB proto-oncogene like 2 ISS OMIM:601626 MouseDO NCBI chr 3:159,421,638...159,450,087
Ensembl chr 3:159,421,671...159,450,086 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:25956709 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240 		JBrowse link
G Myh11 myosin heavy chain 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18206229 PMID:27798625 NCBI chr10:764,421...859,184
Ensembl chr10:764,421...859,184 		JBrowse link
G Nat2 N-acetyltransferase 2 susceptibility
no_association		 ISO DNA:polymorphisms,haplotype: :
DNA:polymorphism: :		 RGD PMID:21888617, PMID:11352872 RGD:11532769, RGD:11532773 NCBI chr16:23,960,709...23,991,570
Ensembl chr16:23,961,067...23,991,570 		JBrowse link
G Ncoa2 nuclear receptor coactivator 2 ISO human gene in a mouse model;DNA:translocation:exon RGD PMID:12676584 RGD:9590334 NCBI chr 5:5,466,544...5,696,540
Ensembl chr 5:5,616,483...5,694,598 		JBrowse link
G Nectin2 nectin cell adhesion molecule 2 ISO CTD Direct Evidence: therapeutic CTD PMID:29855615 NCBI chr 1:80,631,449...80,666,617
Ensembl chr 1:80,631,450...80,666,585 		JBrowse link
G Nf1 neurofibromin 1 severity
disease_progression		 ISO CTD Direct Evidence: marker/mechanism
DNA:deletion: :		 CTD PMID:21441929 PMID:25822087, PMID:23460398, PMID:12518368 RGD:12789444, RGD:12754447 NCBI chr10:66,732,460...66,928,706
Ensembl chr10:66,690,133...66,928,903 		JBrowse link
G Nos3 nitric oxide synthase 3 disease_progression ISO DNA:polymorphgism: : 894 G>T(human) RGD PMID:24684492 RGD:11533640 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410 		JBrowse link
G Npm1 nucleophosmin 1 onset
disease_progression		 ISO ClinVar Annotator: match by term: Acute myeloid leukemia
CTD Direct Evidence: marker/mechanism
DNA:mutation:exon:
ClinVar Annotator: match by term: Leukemia, acute myeloid, UMLS MESH term: Acute Myelogenous Leukemia		 ClinVar
CTD
OMIM		 PMID:15659725 PMID:19657110 PMID:19822134 PMID:20026798 PMID:21441929 PMID:23877794 PMID:27992414 PMID:30420649 PMID:32581362, PMID:15659725, PMID:21441929, PMID:25992555, PMID:17957027, PMID:24184354, PMID:15659732 RGD:1600907, RGD:11534990, RGD:11070453, RGD:11049474, RGD:11049471, RGD:1600902 NCBI chr10:18,080,949...18,091,062
Ensembl chr10:18,080,950...18,090,950 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 ISO DNA:SNP: :609C>T (human) RGD PMID:19456854 RGD:10769358 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180 		JBrowse link
G Nras NRAS proto-oncogene, GTPase disease_progression ISO ClinVar Annotator: match by term: Acute myelogenous leukemia
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Leukemia, acute myelogenous
ClinVar Annotator: match by term: Acute myeloid leukemia
DNA:missense mutation:cds:		 ClinVar
CTD		 PMID:1654209 PMID:2278970 PMID:2407301 PMID:2674680 PMID:2989702 PMID:3102434 PMID:3122217 PMID:6587382 PMID:8120410 PMID:10598665 PMID:10821536 PMID:12460918 PMID:12727991 PMID:14508525 PMID:14982869 PMID:15046639 PMID:15831708 PMID:15899789 PMID:15951308 PMID:16273091 PMID:16291983 PMID:16434492 PMID:16518851 PMID:17332249 PMID:17384584 PMID:17517660 PMID:17699718 PMID:18375819 PMID:18390968 PMID:18633438 PMID:18668139 PMID:18794081 PMID:18948947 PMID:18952898 PMID:19047918 PMID:19075190 PMID:19657110 PMID:19775298 PMID:19880792 PMID:19966803 PMID:20130576 PMID:20149136 PMID:20179705 PMID:20406486 PMID:20619739 PMID:20736745 PMID:21079152 PMID:21107323 PMID:21263000 PMID:21305640 PMID:21576590 PMID:21729679 PMID:21829508 PMID:22144181 PMID:22407852 PMID:22499344 PMID:22718121 PMID:22761467 PMID:22773810 PMID:22962325 PMID:23076151 PMID:23134356 PMID:23392294 PMID:23400451 PMID:23414587 PMID:23431193 PMID:23515407 PMID:23538902 PMID:23569304 PMID:23614898 PMID:24006476 PMID:24033266 PMID:24148783 PMID:24284627 PMID:24370118 PMID:24671188 PMID:25157968 PMID:25348872 PMID:25695684 PMID:26619011 PMID:26821351 PMID:27050078 PMID:27992414 PMID:28098151 PMID:28492532 PMID:28594414 PMID:28780248, PMID:21283084, PMID:18952898, PMID:25204082 RGD:11060151, RGD:11070616, RGD:11535045 NCBI chr 2:205,553,119...205,563,716
Ensembl chr 2:205,553,163...205,560,791 		JBrowse link
G Nsd1 nuclear receptor binding SET domain protein 1 severity ISO DNA:translocations:multiple (human) RGD PMID:23630019 RGD:9590149 NCBI chr17:9,840,859...9,955,391
Ensembl chr17:9,844,133...9,952,898 		JBrowse link
G Ntrk3 neurotrophic receptor tyrosine kinase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29119387 NCBI chr 1:139,890,537...140,262,503
Ensembl chr 1:139,890,560...140,262,503 		JBrowse link
G Nup214 nucleoporin 214 ISO OMIM NCBI chr 3:9,227,869...9,236,878
NCBI chr 3:10,993,584...11,070,638
Ensembl chr 3:9,227,823...9,236,736
Ensembl chr 3:9,227,823...9,236,736 		JBrowse link
G Nup98 nucleoporin 98 and 96 precursor ISO CTD Direct Evidence: marker/mechanism CTD PMID:21441929 NCBI chr 1:167,213,866...167,308,851
Ensembl chr 1:167,213,866...167,308,851 		JBrowse link
G Pax5 paired box 5 ISO ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:25741868 NCBI chr 5:60,007,587...60,191,973
Ensembl chr 5:60,007,587...60,191,941 		JBrowse link
G Pdcd1 programmed cell death 1 treatment ISO RGD PMID:26712908 RGD:41410789 NCBI chr 9:101,305,742...101,319,937
Ensembl chr 9:101,307,764...101,319,845 		JBrowse link
G Pde4b phosphodiesterase 4B ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 5:121,759,236...122,136,814
Ensembl chr 5:121,952,977...122,136,814 		JBrowse link
G Picalm phosphatidylinositol binding clathrin assembly protein susceptibility ISO DNA:inversion: :inv(11)(q14q23) OMIM PMID:12461747 RGD:1600760 NCBI chr 1:154,377,229...154,458,966
Ensembl chr 1:154,377,247...154,458,425 		JBrowse link
G Pim2 Pim-2 proto-oncogene, serine/threonine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19458359 NCBI chr  X:15,462,621...15,467,890
Ensembl chr  X:15,462,016...15,467,875 		JBrowse link
G Plcb1 phospholipase C beta 1 severity ISO mRNA:increased expression:blood (human) RGD PMID:20516454 RGD:11535940 NCBI chr 3:127,721,244...128,419,565
Ensembl chr 3:128,155,069...128,419,545 		JBrowse link
G Pou4f1 POU class 4 homeobox 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18206229 NCBI chr15:88,618,255...88,622,712
Ensembl chr15:88,620,470...88,622,413 		JBrowse link
G Prame PRAME nuclear receptor transcriptional regulator ISO mRNA:increased expression:bone marrow, mononuclear cell (human) RGD PMID:20376794 RGD:11535023 NCBI chr  X:106,082,984...106,091,256
Ensembl chr  X:106,083,203...106,085,878 		JBrowse link
G Psip1 PC4 and SFRS1 interacting protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 5:101,555,691...101,588,659
Ensembl chr 5:101,555,694...101,588,598 		JBrowse link
G Ptch1 patched 1 ISO ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:25741868 PMID:28492532 PMID:28873162 NCBI chr17:1,032,242...1,085,885
Ensembl chr17:1,029,048...1,093,873 		JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 ISO ClinVar Annotator: match by term: Leukemia, acute myelogenous
ClinVar Annotator: match by term: Acute myeloid leukemia
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD		 PMID:12717436 PMID:14644997 PMID:15385933 PMID:15710330 PMID:15928039 PMID:16358218 PMID:17972951 PMID:19047918 PMID:19179468 PMID:24033266 PMID:25097206 PMID:25395418 PMID:26619011 PMID:27069254 PMID:27992414 PMID:28098151 PMID:30868567 NCBI chr12:40,895,515...40,955,999
Ensembl chr12:40,895,515...40,955,999 		JBrowse link
G Pvr PVR cell adhesion molecule ISO CTD Direct Evidence: therapeutic CTD PMID:29855615 NCBI chr 1:80,820,306...80,835,712
Ensembl chr 1:80,820,050...80,835,701 		JBrowse link
G Pxdn peroxidasin ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 6:48,866,496...48,982,368
Ensembl chr 6:48,866,601...48,980,340 		JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21441929 NCBI chr 3:108,984,029...109,044,420
Ensembl chr 3:108,984,029...109,044,420 		JBrowse link
G Rgs2 regulator of G-protein signaling 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr13:60,846,458...60,849,061
Ensembl chr13:60,846,308...60,849,094 		JBrowse link
G RT1-Bb RT1 class II, locus Bb ISO RGD PMID:20051322, PMID:17237562 RGD:11041763, RGD:11041776 NCBI chr20:4,043,726...4,049,367
Ensembl chr20:4,039,413...4,049,711 		JBrowse link
G Rtel1 regulator of telomere elongation helicase 1 ISO ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:25741868 NCBI chr 3:176,818,012...176,856,531
Ensembl chr 3:176,818,437...176,856,531 		JBrowse link
G Runx1 RUNX family transcription factor 1 disease_progression ISO DNA:translocation
ClinVar Annotator: match by term: Acute myeloid leukemia
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Leukemia, acute myeloid, m0 subtype
DNA:frameshift mutations, missense mutations, nonsense mutations: :multiple		 ClinVar
CTD
OMIM		 PMID:10068652 PMID:10508512 PMID:12200707 PMID:12807882 PMID:15156185 PMID:17234761 PMID:18206229 PMID:19357396 PMID:19387465 PMID:20549580 PMID:22012064 PMID:23817177 PMID:24374719 PMID:24523240 PMID:24616160 PMID:24659740 PMID:25741868 PMID:25840971 PMID:27798625 PMID:28492532 PMID:28513614 PMID:30420649 PMID:31064749, PMID:12760263, PMID:19808697, PMID:11023523 RGD:6482833, RGD:11251704, RGD:11251692 NCBI chr11:32,765,147...33,003,061
Ensembl chr11:32,769,165...33,003,021 		JBrowse link
G Runx1t1 RUNX1 partner transcriptional co-repressor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18206229 PMID:27798625 NCBI chr 5:27,284,921...27,440,802
Ensembl chr 5:27,312,928...27,442,841 		JBrowse link
G Runx3 RUNX family transcription factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18206229 NCBI chr 5:153,507,093...153,531,137
Ensembl chr 5:153,507,093...153,531,137 		JBrowse link
G S100a10 S100 calcium binding protein A10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 2:193,892,589...193,901,236
Ensembl chr 2:193,892,589...193,901,236 		JBrowse link
G S100a8 S100 calcium binding protein A8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21971985 NCBI chr 2:190,073,239...190,074,333
Ensembl chr 2:190,073,815...190,074,354 		JBrowse link
G Septin9 septin 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10339604 NCBI chr10:106,208,308...106,340,747
Ensembl chr10:106,264,434...106,348,490 		JBrowse link
G Sf3b1 splicing factor 3b, subunit 1 ISO ClinVar Annotator: match by term: Acute myeloid leukemia
ClinVar Annotator: match by term: Leukemia, acute myelogenous		 ClinVar PMID:21909114 PMID:21995386 PMID:23395771 PMID:23634996 PMID:26619011 NCBI chr 9:61,594,620...61,634,510
Ensembl chr 9:61,594,620...61,634,510 		JBrowse link
G Sf3b2 splicing factor 3b, subunit 2 ISO ClinVar Annotator: match by term: Leukemia, acute myelogenous ClinVar PMID:26619011 NCBI chr 1:220,645,685...220,665,611
Ensembl chr 1:220,645,672...220,665,603 		JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 1:24,185,451...24,302,309
Ensembl chr 1:24,185,435...24,302,298 		JBrowse link
G Sh3gl1 SH3 domain containing GRB2 like 1, endophilin A2 ISO OMIM NCBI chr 9:11,031,847...11,055,285
Ensembl chr 9:11,031,841...11,055,285 		JBrowse link
G Sod2 superoxide dismutase 2 disease_progression ISO protein:increased expression:serum RGD PMID:1596865, PMID:16769586 RGD:11035286, RGD:11035289 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587 		JBrowse link
G Sparc secreted protein acidic and cysteine rich ISO CTD Direct Evidence: marker/mechanism CTD PMID:18206229 NCBI chr10:40,742,390...40,764,232
Ensembl chr10:40,742,400...40,764,185 		JBrowse link
G Spi1 Spi-1 proto-oncogene ISO CTD Direct Evidence: marker/mechanism CTD PMID:26237430 NCBI chr 3:79,918,127...79,937,708
Ensembl chr 3:79,918,969...79,938,301 		JBrowse link
G Spry4 sprouty RTK signaling antagonist 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25822087 NCBI chr18:32,593,370...32,609,890
Ensembl chr18:32,594,958...32,609,864 		JBrowse link
G Srsf2 serine and arginine rich splicing factor 2 severity ISO DNA:mutations:multiple (human) RGD PMID:22431577 RGD:11039017 NCBI chr10:105,792,779...105,795,986
Ensembl chr10:105,792,779...105,795,958 		JBrowse link
G Srsf4 serine and arginine rich splicing factor 4 ISO mRNA:decreased expression: (human) RGD PMID:22722453 RGD:11039059 NCBI chr 5:150,032,999...150,060,769
Ensembl chr 5:150,032,999...150,060,765 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19796711 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233 		JBrowse link
G Svil supervillin ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr17:55,230,298...55,425,967
Ensembl chr17:55,230,298...55,346,279 		JBrowse link
G Syngr1 synaptogyrin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 7:121,311,008...121,334,437
Ensembl chr 7:121,311,024...121,334,437 		JBrowse link
G Tcea2 transcription elongation factor A2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 3:177,187,686...177,195,898
Ensembl chr 3:177,188,044...177,195,894 		JBrowse link
G Tcl1a Tcl1 family Akt coactivator A ISO ClinVar Annotator: match by term: Leukemia, acute myeloid ClinVar NCBI chr 6:128,888,768...128,894,761
Ensembl chr 6:128,888,768...128,894,761 		JBrowse link
G Tcn2 transcobalamin 2 ISO protein:increased expression:: RGD PMID:1059479 RGD:11060122 NCBI chr14:84,173,992...84,189,299
Ensembl chr14:84,174,138...84,189,266 		JBrowse link
G Tek TEK receptor tyrosine kinase ISO ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:19340004 NCBI chr 5:113,725,717...113,852,799
Ensembl chr 5:113,725,717...113,852,799 		JBrowse link
G Tert telomerase reverse transcriptase disease_progression ISO ClinVar Annotator: match by term: Leukemia, acute myeloid, susceptibility to
ClinVar Annotator: match by term: Acute myeloid leukemia
ClinVar Annotator: match by term: Acute myelocytic leukemia		 OMIM
ClinVar		 PMID:15814878 PMID:17460043 PMID:18460650 PMID:18753630 PMID:18931339 PMID:19147845 PMID:19760749 PMID:19796246 PMID:20966039 PMID:21520173 PMID:21635204 PMID:22476886 PMID:23538340 PMID:23901009 PMID:24033266 PMID:24983628 PMID:25108601 PMID:25741868 PMID:26859482 PMID:28154186 PMID:28492532, PMID:23826993 RGD:11038655 NCBI chr 1:32,250,876...32,275,330
Ensembl chr 1:32,251,714...32,272,476 		JBrowse link
G Tet2 tet methylcytosine dioxygenase 2 disease_progression ISO DNA:deletions RGD PMID:23389918, PMID:25200248 RGD:11038681, RGD:11038682 NCBI chr 2:238,719,389...238,802,975
Ensembl chr 2:238,720,835...238,803,024 		JBrowse link
G Tfpi2 tissue factor pathway inhibitor 2 ISO DNA:hypermethylation:promoter: RGD PMID:22052167 RGD:11060127 NCBI chr 4:28,947,951...28,953,261
Ensembl chr 4:28,947,965...28,953,067 		JBrowse link
G Tfr2 transferrin receptor 2 disease_progression ISO RGD PMID:15015967 RGD:11062090 NCBI chr12:22,177,382...22,194,330
Ensembl chr12:22,177,382...22,194,299 		JBrowse link
G Tgm6 transglutaminase 6 ISO ClinVar Annotator: match by term: Leukemia, acute myeloid, UMLS MESH term: Acute Myelogenous Leukemia ClinVar PMID:21106500 NCBI chr 3:122,644,183...122,680,054
Ensembl chr 3:122,662,086...122,679,128 		JBrowse link
G Tmem127 transmembrane protein 127 ISO ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:20923864 PMID:25741868 PMID:28492532 NCBI chr 3:119,677,575...119,690,371
Ensembl chr 3:119,677,575...119,690,366 		JBrowse link
G Tnfsf10 TNF superfamily member 10 ISO CTD Direct Evidence: therapeutic CTD PMID:12780785 NCBI chr 2:113,008,008...113,026,899
Ensembl chr 2:113,007,549...113,026,899 		JBrowse link
G Tnfsf8 TNF superfamily member 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:9058727 PMID:10512160 PMID:11918534 NCBI chr 5:79,664,779...79,691,547
Ensembl chr 5:79,664,765...79,691,258 		JBrowse link
G Tnfsf9 TNF superfamily member 9 ISO protein:increased expression:serum (human) RGD PMID:11564827 RGD:2317350 NCBI chr 9:9,909,942...9,912,276
Ensembl chr 9:9,909,948...9,912,276 		JBrowse link
G Tp53 tumor protein p53 disease_progression
treatment		 ISO DNA:mutation: :
ClinVar Annotator: match by term: Acute myeloid leukemia
ClinVar Annotator: match by term: Acute myelogenous leukemia
ClinVar Annotator: match by term: Acute myelocytic leukemia
ClinVar Annotator: match by term: Leukemia, acute myelogenous
CTD Direct Evidence: marker/mechanism
DNA:mutations: :		 ClinVar
CTD		 PMID:1359493 PMID:1565143 PMID:1565144 PMID:1569604 PMID:1631137 PMID:1631151 PMID:1683921 PMID:1978757 PMID:2046748 PMID:2113594 PMID:2826609 PMID:7732013 PMID:7887414 PMID:7969167 PMID:8023157 PMID:8062826 PMID:8099841 PMID:8118819 PMID:8164043 PMID:8242631 PMID:8423216 PMID:8425176 PMID:8479749 PMID:8527048 PMID:8633021 PMID:9047394 PMID:9049183 PMID:9242456 PMID:9290701 PMID:9407971 PMID:9546439 PMID:9569050 PMID:9572492 PMID:9598730 PMID:9627118 PMID:9662334 PMID:9825943 PMID:10411893 PMID:10432928 PMID:10589545 PMID:10616528 PMID:10797439 PMID:10864200 PMID:10914716 PMID:10922393 PMID:11051239 PMID:11139324 PMID:11180592 PMID:11315715 PMID:11370630 PMID:11429705 PMID:11479205 PMID:11494139 PMID:11782540 PMID:11793474 PMID:11896595 PMID:11920959 PMID:12124823 PMID:12509279 PMID:12672316 PMID:12700230 PMID:12726864 PMID:12792784 PMID:12826609 PMID:12917626 PMID:14559903 PMID:15004724 PMID:15017592 PMID:15037740 PMID:15381368 PMID:15390294 PMID:15580553 PMID:15607980 PMID:15722483 PMID:15781620 PMID:15825182 PMID:15951970 PMID:15977174 PMID:16209708 PMID:16288208 PMID:16337994 PMID:16401470 PMID:16489069 PMID:16494995 PMID:16508005 PMID:16633321 PMID:16682957 PMID:16778209 PMID:16818505 PMID:16861262 PMID:17015838 PMID:17311302 PMID:17390010 PMID:17401428 PMID:17417627 PMID:17427234 PMID:17530187 PMID:17540308 PMID:17567834 PMID:17606709 PMID:17636407 PMID:17724467 PMID:17875924 PMID:18307025 PMID:18511570 PMID:18555592 PMID:18685109 PMID:19101993 PMID:19336573 PMID:19367569 PMID:19378321 PMID:19405127 PMID:19462533 PMID:19556618 PMID:19681600 PMID:19834951 PMID:19930417 PMID:20013323 PMID:20028212 PMID:20113312 PMID:20127978 PMID:20128691 PMID:20308654 PMID:20407015 PMID:20506564 PMID:20516128 PMID:20522432 PMID:20693561 PMID:20805372 PMID:21056685 PMID:21187651 PMID:21232794 PMID:21305319 PMID:21343334 PMID:21356188 PMID:21483000 PMID:21484931 PMID:21514416 PMID:21519010 PMID:21535297 PMID:21552135 PMID:21601526 PMID:21761402 PMID:22090360 PMID:22110706 PMID:22114072 PMID:22186996 PMID:22265402 PMID:22427690 PMID:22540896 PMID:22713868 PMID:22811390 PMID:22862161 PMID:22899716 PMID:22915647 PMID:22919068 PMID:22923379 PMID:22999923 PMID:23161690 PMID:23172776 PMID:23246812 PMID:23265383 PMID:23315175 PMID:23334668 PMID:23538418 PMID:23630318 PMID:23667202 PMID:23713777 PMID:23950206 PMID:23967324 PMID:24033266 PMID:24038938 PMID:24256616 PMID:24381225 PMID:24395441 PMID:24487413 PMID:24501221 PMID:24573247 PMID:24603336 PMID:24641375 PMID:24651012 PMID:24651015 PMID:24677579 PMID:24702488 PMID:24744791 PMID:24810334 PMID:25157968 PMID:25339994 PMID:25433984 PMID:25503501 PMID:25525159 PMID:25584008 PMID:25587027 PMID:25741868 PMID:25787918 PMID:25822087 PMID:25896519 PMID:25925845 PMID:25927356 PMID:25945745 PMID:25952993 PMID:26014290 PMID:26230955 PMID:26425688 PMID:26467025 PMID:26497680 PMID:26534844 PMID:26554828 PMID:26585234 PMID:26619011 PMID:26659639 PMID:26681312 PMID:26787237 PMID:26822237 PMID:26845104 PMID:27022024 PMID:27276561 PMID:27374712 PMID:27463065 PMID:27501770 PMID:27533082 PMID:27622479 PMID:27680515 PMID:27683180 PMID:27714481 PMID:27724982 PMID:27873457 PMID:27895058 PMID:27959731 PMID:28135145 PMID:28152038 PMID:28369373 PMID:28453743 PMID:28472496 PMID:28476805 PMID:28477316 PMID:28492532 PMID:28724667 PMID:28861920 PMID:28975465 PMID:29025599 PMID:29070607 PMID:29324801 PMID:29478780 PMID:29489754 PMID:29752822 PMID:29753700 PMID:29979965 PMID:30076369 PMID:30128536 PMID:30216591 PMID:30224644 PMID:30311369 PMID:30327374 PMID:30352134 PMID:30720243 PMID:30816478 PMID:30840781 PMID:31016814 PMID:31206626 PMID:31300551 PMID:31775759 PMID:32000721 PMID:32295079, PMID:24836762, PMID:25412846, PMID:25573287 RGD:11073714, RGD:11057925, RGD:11075071 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449 		JBrowse link
G Trh thyrotropin releasing hormone ISO CTD Direct Evidence: marker/mechanism CTD PMID:18206229 NCBI chr 4:124,110,716...124,113,242
Ensembl chr 4:124,110,716...124,113,242 		JBrowse link
G Trio trio Rho guanine nucleotide exchange factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:18206229 NCBI chr 2:80,471,398...80,769,313
Ensembl chr 2:80,473,202...80,667,481 		JBrowse link
G Tsc1 TSC complex subunit 1 ISO ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:25741868 NCBI chr 3:7,219,955...7,269,063
Ensembl chr 3:7,237,192...7,265,145 		JBrowse link
G Tsc2 TSC complex subunit 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19250671 NCBI chr10:13,962,006...13,996,684
Ensembl chr10:13,961,947...13,996,584 		JBrowse link
G Tubb2a tubulin, beta 2A class IIa ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr17:31,493,145...31,496,827
Ensembl chr17:31,493,107...31,498,651 		JBrowse link
G Tyms thymidylate synthetase susceptibility ISO DNA:repeats,insertion/deletion:5'UTR, 3'UTR: RGD PMID:18774170 RGD:11075096 NCBI chr 9:121,918,875...121,931,564
Ensembl chr 9:121,918,947...121,931,564 		JBrowse link
G U2af1 U2 small nuclear RNA auxiliary factor 1 ISO ClinVar Annotator: match by term: Acute myeloid leukemia
ClinVar Annotator: match by term: Leukemia, acute myelogenous		 ClinVar PMID:22158538 PMID:23029227 PMID:23861105 PMID:24498085 PMID:26619011 NCBI chr20:10,396,652...10,407,564
Ensembl chr20:10,396,621...10,407,554 		JBrowse link
G Vegfa vascular endothelial growth factor A disease_progression ISO DNA:SNP,haplotype: :(rs3025039),(rs699947),(rs833061)(human) RGD PMID:17983459 RGD:13432134 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681 		JBrowse link
G Vopp1 VOPP1 WW domain binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:18206229 NCBI chr 4:88,441,067...88,515,141
Ensembl chr 4:88,441,067...88,515,138 		JBrowse link
G Vsig4 V-set and immunoglobulin domain containing 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18206229 NCBI chr  X:65,370,851...65,400,298
Ensembl chr  X:65,370,851...65,400,298 		JBrowse link
G Wt1 WT1 transcription factor ISO ClinVar Annotator: match by term: Acute myeloid leukemia
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD		 PMID:19822134 PMID:24374862 PMID:24422723 PMID:24521058 PMID:24659740 PMID:24667279 PMID:24671364 PMID:25741868 PMID:27992414 NCBI chr 3:95,133,221...95,180,574
Ensembl chr 3:95,133,713...95,180,564 		JBrowse link
G Zbtb7a zinc finger and BTB domain containing 7a ISO CTD Direct Evidence: marker/mechanism CTD PMID:27798625 NCBI chr 7:11,429,266...11,446,119
Ensembl chr 7:11,432,049...11,444,786 		JBrowse link
G Zfp91 zinc finger protein 91 IDA RGD PMID:12738986 RGD:727221 NCBI chr 1:229,602,499...229,640,906
Ensembl chr 1:229,602,499...229,639,187 		JBrowse link
Acute Myelomonocytic Leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgap26 Rho GTPase activating protein 26 ISO juvenile myelomonocytic leukemia, OMIM:607785 RGD PMID:10908648 RGD:1599311 NCBI chr18:31,807,052...32,557,176
Ensembl chr18:31,812,109...32,207,801 		JBrowse link
G Cbfb core-binding factor subunit beta susceptibility ISO DNA:inversion: ;inv(16)(p13q22)
CTD Direct Evidence: marker/mechanism		 CTD PMID:10958941, PMID:8351518 RGD:1599543 NCBI chr19:37,127,508...37,171,075
Ensembl chr19:37,127,508...37,171,069 		JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B ISO RGD PMID:14681685 RGD:11252167 NCBI chr 5:107,834,353...107,857,428
Ensembl chr 5:107,845,951...107,858,104 		JBrowse link
G Flt3 Fms related receptor tyrosine kinase 3 treatment ISO RGD PMID:22187040 RGD:11049503 NCBI chr12:9,360,439...9,437,004
Ensembl chr12:9,360,672...9,436,570 		JBrowse link
G Gmps guanine monophosphate synthase ISO treatment-related acute type M4 myeloid leukemia; chromosomal translocation resulted in a fusion of MLL and GMPS genes RGD PMID:11110714 RGD:1598998 NCBI chr 2:154,555,967...154,590,662
Ensembl chr 2:154,555,871...154,590,662 		JBrowse link
G Kmt2a lysine methyltransferase 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:8282816 NCBI chr 8:49,110,407...49,185,872
Ensembl chr 8:49,114,990...49,158,971 		JBrowse link
G Myh11 myosin heavy chain 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10958941 NCBI chr10:764,421...859,184
Ensembl chr10:764,421...859,184 		JBrowse link
acute promyelocytic leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12556562 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258 		JBrowse link
G Aqp9 aquaporin 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23563754 NCBI chr 8:77,559,621...77,599,781
Ensembl chr 8:77,559,624...77,599,781 		JBrowse link
G Asxl1 ASXL transcriptional regulator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26285909 NCBI chr 3:148,832,231...148,902,356
Ensembl chr 3:148,837,814...148,900,452 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27770503 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413 		JBrowse link
G Ccl7 C-C motif chemokine ligand 7 IEP RGD PMID:19828696 RGD:5130982 NCBI chr10:69,423,083...69,424,933
Ensembl chr10:69,423,086...69,424,979 		JBrowse link
G Cd44 CD44 molecule (Indian blood group) ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:16208414 PMID:17349212 NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658 		JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B disease_progression ISO DNA:hyprmethylation:promoter: RGD PMID:12750706 RGD:11252187 NCBI chr 5:107,834,353...107,857,428
Ensembl chr 5:107,845,951...107,858,104 		JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:16788101 PMID:26285909 NCBI chr 1:91,363,492...91,366,164
Ensembl chr 1:91,363,492...91,366,164 		JBrowse link
G Cebpe CCAAT/enhancer binding protein epsilon ISO CTD Direct Evidence: therapeutic CTD PMID:16788101 NCBI chr15:33,356,119...33,357,517
Ensembl chr15:33,355,947...33,358,138 		JBrowse link
G Dapk2 death-associated protein kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28978663 NCBI chr 8:71,822,107...71,941,941
Ensembl chr 8:71,822,129...71,941,910 		JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:26285909 NCBI chr 6:28,205,375...28,346,052
Ensembl chr 6:28,235,695...28,340,577 		JBrowse link
G F3 coagulation factor III, tissue factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:16206674, PMID:10726043 RGD:11340216 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272 		JBrowse link
G Flt3 Fms related receptor tyrosine kinase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17454189 PMID:24160850 PMID:26285909 NCBI chr12:9,360,439...9,437,004
Ensembl chr12:9,360,672...9,436,570 		JBrowse link
G Fndc3b fibronectin type III domain containing 3B ISO CTD Direct Evidence: marker/mechanism CTD PMID:28314734 NCBI chr 2:113,109,949...113,415,171
Ensembl chr 2:113,112,902...113,345,577 		JBrowse link
G Gli1 GLI family zinc finger 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23867347 NCBI chr 7:70,620,794...70,633,171
Ensembl chr 7:70,620,766...70,630,338 		JBrowse link
G Gli2 GLI family zinc finger 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23867347 NCBI chr13:34,829,021...35,049,172
Ensembl chr13:34,829,139...35,048,444 		JBrowse link
G Gstt1 glutathione S-transferase theta 1 susceptibility ISO RGD PMID:21875282 RGD:10755406 NCBI chr20:13,799,102...13,816,527
Ensembl chr20:13,799,102...13,816,526 		JBrowse link
G Idh1 isocitrate dehydrogenase (NADP(+)) 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26285909 NCBI chr 9:71,882,108...71,911,645
Ensembl chr 9:71,882,105...71,900,044 		JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26285909 NCBI chr 1:141,874,354...141,893,674
Ensembl chr 1:141,866,283...141,893,705 		JBrowse link
G Ifng interferon gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:22617429 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419 		JBrowse link
G Il17a interleukin 17A ISO CTD Direct Evidence: marker/mechanism CTD PMID:22617429 NCBI chr 9:26,841,299...26,844,786
Ensembl chr 9:26,841,299...26,844,786 		JBrowse link
G Irf2bp2 interferon regulatory factor 2 binding protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25583766 NCBI chr19:59,497,021...59,502,298
Ensembl chr19:59,499,876...59,502,161 		JBrowse link
G Itgal integrin subunit alpha L ISO CTD Direct Evidence: marker/mechanism CTD PMID:16764927 NCBI chr 1:198,744,053...198,781,745
Ensembl chr 1:198,744,050...198,781,750 		JBrowse link
G Itgam integrin subunit alpha M ISO CTD Direct Evidence: marker/mechanism CTD PMID:16764927 NCBI chr 1:199,495,312...199,545,738
Ensembl chr 1:199,495,298...199,623,960 		JBrowse link
G Itgax integrin subunit alpha X ISO CTD Direct Evidence: marker/mechanism CTD PMID:16764927 NCBI chr 1:199,555,560...199,576,948
Ensembl chr 1:199,555,722...199,576,932 		JBrowse link
G Itgb2 integrin subunit beta 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16764927 NCBI chr20:11,777,773...11,815,647
Ensembl chr20:11,777,783...11,815,647 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:26285909 NCBI chr14:35,072,131...35,149,638
Ensembl chr14:35,072,108...35,149,610 		JBrowse link
G Kmt2e lysine methyltransferase 2E severity ISO mRNA:decreased expression:peripheral blood, bone marrow, mononuclear cells (human) RGD PMID:24796963 RGD:9588539 NCBI chr 4:8,187,751...8,255,578
Ensembl chr 4:8,187,751...8,255,514 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor onset ISO mRNA:increased expression:promyelocyte: RGD PMID:21059853, PMID:21059853 RGD:11532756, RGD:11532756 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240 		JBrowse link
G Ncam1 neural cell adhesion molecule 1 disease_progression ISO RGD PMID:24296270 RGD:40907062 NCBI chr 8:53,836,797...54,134,881
Ensembl chr 8:53,839,098...53,901,358 		JBrowse link
G Npm1 nucleophosmin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14508522 PMID:26285909, PMID:15659732 RGD:1600902 NCBI chr10:18,080,949...18,091,062
Ensembl chr10:18,080,950...18,090,950 		JBrowse link
G Nras NRAS proto-oncogene, GTPase ISO CTD Direct Evidence: marker/mechanism CTD PMID:26285909 NCBI chr 2:205,553,119...205,563,716
Ensembl chr 2:205,553,163...205,560,791 		JBrowse link
G Numa1 nuclear mitotic apparatus protein 1 ISO OMIM NCBI chr 1:167,044,544...167,091,453
Ensembl chr 1:167,051,209...167,091,453 		JBrowse link
G Plat plasminogen activator, tissue type ISO protein:increased expression:leukocyte (human) RGD PMID:10861807 RGD:11541060 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889 		JBrowse link
G Pml PML nuclear body scaffold ISO CTD Direct Evidence: marker/mechanism
human PML/RARA gene fusion in a mouse model		 CTD PMID:8616088 PMID:10742073 PMID:14706140 PMID:16788101 PMID:16835227 PMID:16891316 PMID:16935935 PMID:17294898 PMID:17649720 PMID:19029980 PMID:19035177 PMID:19884644 PMID:19887701 PMID:21345080 PMID:21613260 PMID:22213200 PMID:23208507 PMID:23734343 PMID:26285909 PMID:26728337, PMID:9122233 RGD:41404695 NCBI chr 8:63,002,515...63,034,310
Ensembl chr 8:63,004,870...63,034,226 		JBrowse link
G Prame PRAME nuclear receptor transcriptional regulator severity ISO mRNA:increased expression:bone marrow (human) RGD PMID:18815192 RGD:11535037 NCBI chr  X:106,082,984...106,091,256
Ensembl chr  X:106,083,203...106,085,878 		JBrowse link
G Prkar1a protein kinase cAMP-dependent type I regulatory subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:17712046 NCBI chr10:97,940,705...97,959,199
Ensembl chr10:97,940,705...97,957,336 		JBrowse link
G Rap1gap Rap1 GTPase-activating protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:22614916 NCBI chr 5:156,008,868...156,074,350
Ensembl chr 5:156,026,911...156,074,395 		JBrowse link
G Rara retinoic acid receptor, alpha ISO CTD Direct Evidence: marker/mechanism CTD
OMIM		 PMID:8616088 PMID:10742073 PMID:14508522 PMID:14706140 PMID:16239915 PMID:16788101 PMID:16835227 PMID:16891316 PMID:16935935 PMID:17294898 PMID:17649720 PMID:17712046 PMID:19029980 PMID:19035177 PMID:19884644 PMID:19887701 PMID:21613260 PMID:22213200 PMID:23208507 PMID:25583766 PMID:26285909 PMID:26728337 PMID:28314734, PMID:15659732 RGD:1600902 NCBI chr10:86,838,819...86,884,224
Ensembl chr10:86,860,685...86,884,210 		JBrowse link
G Smo smoothened, frizzled class receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:23867347 NCBI chr 4:57,019,941...57,041,779
Ensembl chr 4:57,019,941...57,042,770 		JBrowse link
G Tet2 tet methylcytosine dioxygenase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26285909 NCBI chr 2:238,719,389...238,802,975
Ensembl chr 2:238,720,835...238,803,024 		JBrowse link
G Thbd thrombomodulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16206674 NCBI chr 3:142,748,673...142,752,325
Ensembl chr 3:142,748,674...142,752,325 		JBrowse link
G Tmem127 transmembrane protein 127 ISO ClinVar Annotator: match by term: Acute promyelocytic leukemia ClinVar PMID:25741868 PMID:28492532 NCBI chr 3:119,677,575...119,690,371
Ensembl chr 3:119,677,575...119,690,366 		JBrowse link
G Top2a DNA topoisomerase II alpha ISO ClinVar Annotator: match by term: Dna topoisomerase II, resistance to inhibition of, by amsacrine ClinVar PMID:1651812 NCBI chr10:86,901,467...86,930,947
Ensembl chr10:86,901,007...86,932,154 		JBrowse link
G Wt1 WT1 transcription factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:26285909 NCBI chr 3:95,133,221...95,180,574
Ensembl chr 3:95,133,713...95,180,564 		JBrowse link
G Zbtb16 zinc finger and BTB domain containing 16 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23208507, PMID:8387545 RGD:1599922 NCBI chr 8:52,980,226...53,146,765
Ensembl chr 8:52,985,313...53,146,953 		JBrowse link
atypical chronic myeloid leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgfr1 Fibroblast growth factor receptor 1 ISO RGD PMID:15050920 RGD:11352668 NCBI chr16:71,265,390...71,319,046
Ensembl chr16:71,266,248...71,319,449 		JBrowse link
G Setbp1 SET binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23222956 NCBI chr18:75,090,733...75,432,446
Ensembl chr18:75,095,632...75,207,306 		JBrowse link
Blast Crisis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aicda activation-induced cytidine deaminase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21570118 NCBI chr 4:155,359,909...155,371,104
Ensembl chr 4:155,359,921...155,369,671 		JBrowse link
G Bcr BCR activator of RhoGEF and GTPase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21570118 NCBI chr20:14,421,250...14,546,406
Ensembl chr20:14,421,141...14,545,772 		JBrowse link
G Esr2 estrogen receptor 2 ISO RGD PMID:12740446 RGD:734951 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251 		JBrowse link
G Hmox1 heme oxygenase 1 ISO RGD PMID:22139798 RGD:10755566 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456 		JBrowse link
G Mir150 microRNA 150 ISO miRNA:decreased expression:leukocytes RGD PMID:21501493 RGD:13782140 NCBI chr 1:101,115,974...101,116,058
Ensembl chr 1:101,115,974...101,116,058 		JBrowse link
G Tcn2 transcobalamin 2 ISO protein:increased expression:: RGD PMID:1059479 RGD:11060122 NCBI chr14:84,173,992...84,189,299
Ensembl chr14:84,174,138...84,189,266 		JBrowse link
chronic myeloid leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A treatment
susceptibility		 ISO DNA:SNPs: :1236T>C,2677G>A(human)
DNA:SNP, haplotype: :3435C>T (human)		 RGD PMID:24581936, PMID:26250462 RGD:11081178, RGD:11081180 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 treatment ISO DNA:haploltype: :-24C>T, 1249G>A, 3972C>T(human) RGD PMID:25060527 RGD:11080961 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 treatment
susceptibility		 ISO DNA:SNP: :421C>A(human)
DNA:haplotype:cds: p.Q141K,p.V12M,(rs2231142),(rs2725252)(human)
DNA:SNP,haplotype: :C>A421(human)		 RGD PMID:24581936, PMID:24123600, PMID:26250462 RGD:11081178, RGD:11081181, RGD:11081180 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621 		JBrowse link
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase susceptibility
treatment		 ISO ClinVar Annotator: match by term: Chronic myelogenous leukemia
ClinVar Annotator: match by term: ABL1-Related Disorder
DNA:gene fusion
ClinVar Annotator: match by term: Chronic myeloid leukemia
ClinVar Annotator: match by term: Chronic myeloid leukemia, resistant to imatinib
ClinVar Annotator: match by term: Leukemia, philadelphia chromosome-positive, resistant to imatinib
CTD Direct Evidence: marker/mechanism
DNA:missense mutations: :multiple		 ClinVar
OMIM
CTD		 PMID:10988075 PMID:11423618 PMID:11567109 PMID:11569495 PMID:11853795 PMID:11861307 PMID:11964322 PMID:12130516 PMID:12399961 PMID:12576318 PMID:12623848 PMID:12663457 PMID:12783380 PMID:14559829 PMID:14745431 PMID:15194504 PMID:15256422 PMID:15381060 PMID:15510211 PMID:15604220 PMID:17008892 PMID:17114651 PMID:17189410 PMID:18223278 PMID:18354488 PMID:18615627 PMID:18673174 PMID:18757400 PMID:18828913 PMID:19164531 PMID:19264234 PMID:19466505 PMID:19557636 PMID:19652056 PMID:19768693 PMID:19811824 PMID:20010464 PMID:20367437 PMID:20512393 PMID:20537386 PMID:20557306 PMID:20607847 PMID:20697894 PMID:20702476 PMID:20963643 PMID:21221851 PMID:21489624 PMID:21505103 PMID:21509757 PMID:21562040 PMID:21605905 PMID:21762985 PMID:21872826 PMID:21888027 PMID:21895409 PMID:21908430 PMID:22210874 PMID:22306673 PMID:22772060 PMID:22870928 PMID:22912393 PMID:23355941 PMID:23540562 PMID:23575252 PMID:23676790 PMID:24109527 PMID:24236021 PMID:24456693 PMID:25152116 PMID:25157968 PMID:25686603 PMID:28492532 PMID:31775759, PMID:3021820, PMID:25133686, PMID:21481795, PMID:12067277, PMID:23289634 RGD:1598673, RGD:13674161, RGD:11038814, RGD:14392796, RGD:11038807 NCBI chr 3:10,041,820...10,145,076
Ensembl chr 3:10,041,826...10,144,388 		JBrowse link
G Abl2 ABL proto-oncogene 2, non-receptor tyrosine kinase TAS RGD PMID:7773298 RGD:1298615 NCBI chr13:74,154,533...74,333,244
Ensembl chr13:74,154,835...74,333,244 		JBrowse link
G Ace angiotensin I converting enzyme ISO RGD PMID:19761684 RGD:11039056 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822 		JBrowse link
G Agt angiotensinogen ISO RGD PMID:19761684 RGD:11039056 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 ISO protein:increased phosphorylation:blood RGD PMID:17900686 RGD:13674160 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase ISO CTD Direct Evidence: therapeutic CTD PMID:19503090 PMID:19823023 NCBI chr 4:148,398,004...148,446,308
Ensembl chr 4:148,398,892...148,446,303 		JBrowse link
G Arntl aryl hydrocarbon receptor nuclear translocator-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:16999817 NCBI chr 1:178,039,002...178,137,469
Ensembl chr 1:178,039,063...178,137,465 		JBrowse link
G Bcl2l1 Bcl2-like 1 ISO RGD PMID:20728382 RGD:11353850 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810 		JBrowse link
G Bcr BCR activator of RhoGEF and GTPase susceptibility
treatment
disease_progression		 ISO DNA:gene fusion
BCR/ABL fusion
CTD Direct Evidence: marker/mechanism
DNA:methylation: :
DNA:translocations:cds:		 CTD
OMIM		 PMID:15604220 PMID:18673174 PMID:21908430, PMID:3101769, PMID:12613514, PMID:25133686, PMID:12067277, PMID:7683349, PMID:2683759, PMID:1362728 RGD:1600510, RGD:41404631, RGD:13674161, RGD:14392796, RGD:11038783, RGD:11038776, RGD:11038775 NCBI chr20:14,421,250...14,546,406
Ensembl chr20:14,421,141...14,545,772 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 ISO CTD Direct Evidence: therapeutic CTD PMID:16254145 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413 		JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase ISO ClinVar Annotator: match by term: Chronic myeloid leukemia ClinVar PMID:24033266 PMID:24446311 PMID:25157968 PMID:26619011 NCBI chr 4:67,389,331...67,520,549
Ensembl chr 4:67,396,192...67,520,356 		JBrowse link
G Ca9 carbonic anhydrase 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17157168 NCBI chr 5:59,008,277...59,015,535
Ensembl chr 5:59,008,933...59,015,528 		JBrowse link
G Cd36 CD36 molecule ISO protein:increased expression:platelet, cell surface RGD PMID:8555064 RGD:11041099 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749 		JBrowse link
G Cd40 CD40 molecule ISO protein:increased expression:peripheral blood, dendritic cell (human) RGD PMID:16527350 RGD:11520794 NCBI chr 3:161,519,789...161,534,943
Ensembl chr 3:161,519,743...161,534,704 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B ISO Protein:increased expression:Blood, common myeloid progenitor, CD34-positive RGD PMID:20200561 RGD:13673878 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A treatment ISO RGD PMID:16533530 RGD:11251777 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175 		JBrowse link
G Cdkn2a_v1 cyclin-dependent kinase inhibitor 2A, variant 1 treatment ISO RGD PMID:16533530 RGD:11251777
G Cdkn2a_v2 cyclin-dependent kinase inhibitor 2A, variant 2 treatment ISO RGD PMID:16533530 RGD:11251777
G Chordc1 cysteine and histidine rich domain containing 1 ISS OMIM:608232 MouseDO NCBI chr 8:17,421,552...17,445,513
Ensembl chr 8:17,421,557...17,446,165 		JBrowse link
G Crkl CRK like proto-oncogene, adaptor protein ISO protein:increased phosphorylation:blood RGD PMID:17900686 RGD:13674160 NCBI chr11:87,338,606...87,356,644
Ensembl chr11:87,778,312...87,815,043 		JBrowse link
G Cry1 cryptochrome circadian regulator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16999817 NCBI chr 7:24,534,593...24,634,098
Ensembl chr 7:24,534,615...24,634,097 		JBrowse link
G Cry2 cryptochrome circadian regulator 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16999817 NCBI chr 3:81,314,151...81,344,143
Ensembl chr 3:81,314,149...81,344,110 		JBrowse link
G Csf3r colony stimulating factor 3 receptor ISO ClinVar Annotator: match by term: Chronic myeloid leukemia
ClinVar Annotator: match by term: Chronic myelogenous leukemia		 ClinVar PMID:23604229 PMID:23634996 PMID:23656643 PMID:24081659 PMID:24403076 PMID:24614839 PMID:24854193 PMID:25491280 PMID:25741868 PMID:25932451 PMID:26875968 PMID:27148573 PMID:27581359 PMID:28209919 PMID:28219221 PMID:28492532 PMID:28762112 PMID:30967555 NCBI chr 5:144,031,353...144,051,966
Ensembl chr 5:144,031,402...144,051,600 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 treatment ISO DNA:polymorphism:cds:4889A>G(p.I462V)(human) RGD PMID:26464823 RGD:11352729 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147 		JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 susceptibility
treatment		 ISO DNA:polymorphism:intron :6986A>G(human)
DNA:SNP::rs776746(human)		 RGD PMID:21039054, PMID:19584153 RGD:11353798, RGD:11353810 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399 		JBrowse link
G Dnmt1 DNA methyltransferase 1 disease_progression ISO RGD PMID:11222358 RGD:9588667 NCBI chr 8:21,922,515...21,968,495
Ensembl chr 8:21,922,515...21,968,495 		JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha disease_progression ISO RGD PMID:11222358 RGD:9588667 NCBI chr 6:28,205,375...28,346,052
Ensembl chr 6:28,235,695...28,340,577 		JBrowse link
G Dnmt3b DNA methyltransferase 3 beta disease_progression ISO RGD PMID:11222358 RGD:9588667 NCBI chr 3:149,131,541...149,170,061
Ensembl chr 3:149,131,785...149,208,786 		JBrowse link
G E2f1 E2F transcription factor 1 ISO mRNA:increased expression:blood RGD PMID:26460262 RGD:13674165 NCBI chr 3:150,062,895...150,073,721
Ensembl chr 3:150,047,826...150,073,721 		JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit ISO DNA:polymorphism: :p.K751Q (human)
DNA:polymorphism: :p.K751Q (rs13181) (human)		 RGD PMID:24955348, PMID:25311495 RGD:11252188, RGD:11060463 NCBI chr 1:80,293,574...80,307,334
Ensembl chr 1:80,293,566...80,307,344 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit ISO mRNA:increased expression:bone marrow mononuclear cells (human) RGD PMID:27070757 RGD:13782088 NCBI chr 4:77,284,404...77,347,011
Ensembl chr 4:77,284,404...77,347,011 		JBrowse link
G Fas Fas cell surface death receptor susceptibility ISO DNA:polymorphisms, haplotype:promoter: -670 G>A, -1377 G>A (human) RGD PMID:26563376 RGD:11049146 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790 		JBrowse link
G Faslg Fas ligand susceptibility ISO DNA:polymorphism:promoter: -844 T>C(human) RGD PMID:26563376 RGD:11049146 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705 		JBrowse link
G Fcgr2a Fc fragment of IgG receptor IIa ISO RGD PMID:8632671 RGD:11344957 NCBI chr13:91,146,878...91,163,691
Ensembl chr13:91,168,973...91,198,036
Ensembl chr13:91,168,973...91,198,036 		JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 ISO mRNA:increased expression:peripheral blood (human) RGD PMID:14562121 RGD:36947884 NCBI chr14:82,272,322...82,287,739
Ensembl chr14:82,273,070...82,287,706 		JBrowse link
G Gab2 GRB2-associated binding protein 2 disease_progression ISO protein:increased expression:bone marrow RGD PMID:22858987 RGD:13699433 NCBI chr 1:162,082,876...162,283,379
Ensembl chr 1:162,083,030...162,279,727 		JBrowse link
G Gpx1 glutathione peroxidase 1 no_association ISO DNA:polymorphism: :p.P198L (human) RGD PMID:25436036 RGD:11352762 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20843134 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 IMP rat gene in a mouse model RGD PMID:19861684 RGD:9685380 NCBI chr11:74,312,837...74,315,249
Ensembl chr11:74,312,806...74,315,248 		JBrowse link
G Hmmr hyaluronan-mediated motility receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:17157168 NCBI chr10:25,861,490...25,890,639
Ensembl chr10:25,861,490...25,890,639 		JBrowse link
G Hmox1 heme oxygenase 1 ISO RGD PMID:22139798 RGD:10755566 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23777986 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762 		JBrowse link
G Il10 interleukin 10 treatment ISO RGD PMID:20305143 RGD:11049154 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392 		JBrowse link
G Il1b interleukin 1 beta severity ISO RGD PMID:7949186 RGD:10450889 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726 		JBrowse link
G Il1rn interleukin 1 receptor antagonist severity ISO RGD PMID:7949186 RGD:10450889 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614 		JBrowse link
G Insl6 insulin-like 6 ISO ClinVar Annotator: match by term: Chronic myelogenous leukemia ClinVar PMID:15781101 PMID:15793561 PMID:15858187 PMID:16081687 PMID:16247455 PMID:16293597 PMID:16325696 PMID:16603627 PMID:16707754 PMID:16709929 PMID:16762626 PMID:17989398 PMID:18256599 PMID:18394554 PMID:19036091 PMID:19287384 PMID:19293426 PMID:20339092 PMID:20631743 PMID:20703299 PMID:21120162 PMID:21689158 PMID:22041374 PMID:22422826 PMID:22571758 PMID:22818858 PMID:22829971 PMID:23115274 PMID:24404189 PMID:24986690 PMID:25043017 PMID:25157968 PMID:25671252 PMID:25741868 PMID:32581362 NCBI chr 1:247,473,292...247,476,827
Ensembl chr 1:247,473,292...247,476,827 		JBrowse link
G Jak2 Janus kinase 2 ISO ClinVar Annotator: match by term: Chronic myelogenous leukemia ClinVar PMID:15781101 PMID:15793561 PMID:15858187 PMID:16081687 PMID:16247455 PMID:16293597 PMID:16325696 PMID:16603627 PMID:16707754 PMID:16709929 PMID:16762626 PMID:17989398 PMID:18256599 PMID:18394554 PMID:19036091 PMID:19287384 PMID:19293426 PMID:20339092 PMID:20631743 PMID:20703299 PMID:21120162 PMID:21689158 PMID:22041374 PMID:22422826 PMID:22571758 PMID:22818858 PMID:22829971 PMID:23115274 PMID:24404189 PMID:24986690 PMID:25043017 PMID:25157968 PMID:25671252 PMID:25741868 PMID:32581362 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase ISO ClinVar Annotator: match by term: Chronic myelogenous leukemia ClinVar PMID:16307017 PMID:22703879 PMID:24728327 PMID:25741868 PMID:31775759 NCBI chr14:35,072,131...35,149,638
Ensembl chr14:35,072,108...35,149,610 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 ISO CTD Direct Evidence: therapeutic CTD PMID:16818652 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137 		JBrowse link
G Mdm2 MDM2 proto-oncogene onset ISO DNA:SNP:promoter:rs2279744(human) RGD PMID:23818300 RGD:13703044 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328 		JBrowse link
G Mir150 microRNA 150 ISO miRNA:decreased expression:leukocytes RGD PMID:21501493 RGD:13782140 NCBI chr 1:101,115,974...101,116,058
Ensembl chr 1:101,115,974...101,116,058 		JBrowse link
G Mlf1 myeloid leukemia factor 1 ISO RGD PMID:15659732 RGD:1600902 NCBI chr 2:164,549,423...164,582,645
Ensembl chr 2:164,549,455...164,582,643 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO DNA:SNPs: :677C>T, 1298A>C(human) RGD PMID:17156840 RGD:10449408 NCBI chr 5:164,844,642...164,864,360
Ensembl chr 5:164,845,925...164,860,910 		JBrowse link
G Ncstn nicastrin ISS OMIM:608232 MouseDO NCBI chr13:90,451,046...90,467,256
Ensembl chr13:90,451,044...90,467,256 		JBrowse link
G Npm1 nucleophosmin 1 ISO RGD PMID:15659732 RGD:1600902 NCBI chr10:18,080,949...18,091,062
Ensembl chr10:18,080,950...18,090,950 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 ISO DNA:SNP: :609C>T (human) RGD PMID:16235982 RGD:10769357 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180 		JBrowse link
G Nras NRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Chronic myeloid leukemia ClinVar PMID:2674680 PMID:8120410 PMID:12460918 PMID:16291983 PMID:18390968 PMID:18948947 PMID:20130576 PMID:20179705 PMID:23134356 PMID:23414587 PMID:23515407 PMID:25157968 PMID:26619011 NCBI chr 2:205,553,119...205,563,716
Ensembl chr 2:205,553,163...205,560,791 		JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 ISO protein:increased expression:serum (human) RGD PMID:16521495 RGD:11552593 NCBI chr10:94,850,971...94,913,202 JBrowse link
G Per1 period circadian regulator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16999817 NCBI chr10:55,681,761...55,696,557
Ensembl chr10:55,687,050...55,695,994 		JBrowse link
G Per2 period circadian regulator 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16999817 NCBI chr 9:98,555,154...98,597,362
Ensembl chr 9:98,555,169...98,597,359 		JBrowse link
G Per3 period circadian regulator 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16999817 NCBI chr 5:168,088,126...168,123,482
Ensembl chr 5:168,086,998...168,123,395 		JBrowse link
G Prame PRAME nuclear receptor transcriptional regulator ISO mRNA:increased expression:mononuclear cell (human)
CTD Direct Evidence: marker/mechanism		 CTD PMID:17157168, PMID:20838376 RGD:11535035 NCBI chr  X:106,082,984...106,091,256
Ensembl chr  X:106,083,203...106,085,878 		JBrowse link
G Prtn3 proteinase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17157168 NCBI chr 7:12,643,712...12,646,951
Ensembl chr 7:12,643,516...12,646,960 		JBrowse link
G RT1-Ba RT1 class II, locus Ba onset ISO DNA:polymorphism, haplotype RGD PMID:17893434, PMID:17387388 RGD:11041777, RGD:11041781 NCBI chr20:4,066,133...4,070,726
Ensembl chr20:4,066,132...4,070,721 		JBrowse link
G RT1-Bb RT1 class II, locus Bb ISO DNA:polymorphism, haplotype RGD PMID:17893434 RGD:11041777 NCBI chr20:4,043,726...4,049,367
Ensembl chr20:4,039,413...4,049,711 		JBrowse link
G Setbp1 SET binding protein 1 ISO ClinVar Annotator: match by term: Chronic myelogenous leukemia ClinVar PMID:18398855 PMID:18414213 PMID:20436468 PMID:21371013 PMID:23222956 PMID:25741868 NCBI chr18:75,090,733...75,432,446
Ensembl chr18:75,095,632...75,207,306 		JBrowse link
G Sh2b3 SH2B adaptor protein 3 ISS OMIM:608232 MouseDO NCBI chr12:40,261,990...40,265,757
Ensembl chr12:40,244,081...40,265,757 		JBrowse link
G Sipa1 signal-induced proliferation-associated 1 ISS OMIM:608232 MouseDO NCBI chr 1:221,006,305...221,018,820
Ensembl chr 1:221,006,340...221,015,929 		JBrowse link
G Smad4 SMAD family member 4 ISO mRNA:decreased expression:blood RGD PMID:29951173 RGD:13782079 NCBI chr18:69,626,682...69,657,373
Ensembl chr18:69,627,757...69,671,199 		JBrowse link
G Srsf1 serine and arginine rich splicing factor 1 ISO mRNA:increased expression:peripheral blood mononuclear cell (human) RGD PMID:23228155 RGD:11038774 NCBI chr10:75,334,200...75,341,197
Ensembl chr10:75,335,146...75,341,197 		JBrowse link
G Tert telomerase reverse transcriptase ISO CTD Direct Evidence: marker/mechanism CTD PMID:17157168, PMID:15068898 RGD:11038663 NCBI chr 1:32,250,876...32,275,330
Ensembl chr 1:32,251,714...32,272,476 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO protein:increased expression:serum RGD PMID:29951173 RGD:13782079 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199 		JBrowse link
G Vegfa vascular endothelial growth factor A susceptibility ISO DNA:SNP,haplotype: :(rs6999470),(rs833061)(human) RGD PMID:19141860 RGD:13432135 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681 		JBrowse link
G Wt1 WT1 transcription factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:17157168 NCBI chr 3:95,133,221...95,180,574
Ensembl chr 3:95,133,713...95,180,564 		JBrowse link
G Xrcc1 X-ray repair cross complementing 1 susceptibility ISO DNA:SNP:cds :p.R194W(human) RGD PMID:26250462 RGD:11081180 NCBI chr 1:81,412,635...81,441,680
Ensembl chr 1:81,413,353...81,441,678 		JBrowse link
chronic myelomonocytic leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asxl1 ASXL transcriptional regulator 1 disease_progression ISO DNA:mutations:exon: RGD PMID:20880116 RGD:11038767 NCBI chr 3:148,832,231...148,902,356
Ensembl chr 3:148,837,814...148,900,452 		JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B ISO DNA:altered methylation:5'UTR: RGD PMID:12750705 RGD:11252180 NCBI chr 5:107,834,353...107,857,428
Ensembl chr 5:107,845,951...107,858,104 		JBrowse link
G Csf3r colony stimulating factor 3 receptor disease_progression ISO DNA:mutations:multiples: RGD PMID:23774674 RGD:10450469 NCBI chr 5:144,031,353...144,051,966
Ensembl chr 5:144,031,402...144,051,600 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit severity ISO DNA:mutations:multiple (human) RGD PMID:21339759 RGD:10450882 NCBI chr 4:77,284,404...77,347,011
Ensembl chr 4:77,284,404...77,347,011 		JBrowse link
G Kdm6a lysine demethylase 6A ISS MouseDO NCBI chr  X:4,805,493...4,945,788
Ensembl chr  X:4,806,277...4,945,944 		JBrowse link
G Nras NRAS proto-oncogene, GTPase onset ISO RGD PMID:26082490 RGD:11535058 NCBI chr 2:205,553,119...205,563,716
Ensembl chr 2:205,553,163...205,560,791 		JBrowse link
G Tet2 tet methylcytosine dioxygenase 2 ISO DNA:missense mutations, nonsense mutations, splice-site mutations:multiple RGD PMID:20693430 RGD:11038679 NCBI chr 2:238,719,389...238,802,975
Ensembl chr 2:238,720,835...238,803,024 		JBrowse link
familial chronic myelocytic leukemia-like syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irf8 interferon regulatory factor 8 ISS OMIM:600080 MouseDO NCBI chr19:54,314,859...54,336,643
Ensembl chr19:54,314,865...54,336,640 		JBrowse link
Familial Erythroleukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Erbb3 erb-b2 receptor tyrosine kinase 3 susceptibility ISO ClinVar Annotator: match by term: LEUKEMIA, ACUTE MYELOGENOUS, M6 ClinVar
OMIM		 PMID:27416908 NCBI chr 7:2,989,202...3,010,610
Ensembl chr 7:2,989,340...3,010,350 		JBrowse link
Familial Platelet Disorder with Associated Myeloid Malignancy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Runx1 RUNX family transcription factor 1 ISO ClinVar Annotator: match by term: Platelet disorder, Aspirin-like
ClinVar Annotator: match by term: Hereditary thrombocytopenia and hematologic cancer predisposition syndrome
ClinVar Annotator: match by term: Familial platelet disorder with associated myeloid malignancy		 OMIM
ClinVar		 PMID:10068652 PMID:10508512 PMID:11830488 PMID:12060124 PMID:12172547 PMID:12200707 PMID:12393679 PMID:12807882 PMID:14504086 PMID:15156185 PMID:15749889 PMID:17234761 PMID:17290219 PMID:17485549 PMID:17650443 PMID:18478040 PMID:18723428 PMID:19357396 PMID:19387465 PMID:20549580 PMID:20846103 PMID:20880108 PMID:20955399 PMID:22012064 PMID:22318203 PMID:22689681 PMID:23751892 PMID:23753029 PMID:23817177 PMID:23848403 PMID:24100448 PMID:24523240 PMID:24659740 PMID:24764152 PMID:24904105 PMID:25159113 PMID:25741868 PMID:25840971 PMID:26175287 PMID:26316320 PMID:26580448 PMID:26884589 PMID:27112265 PMID:27137476 PMID:27210295 PMID:27418648 PMID:27479822 PMID:28179279 PMID:28240786 PMID:28492532 PMID:28513614 PMID:28659335 PMID:28748566 PMID:28855357 PMID:28933735 PMID:28960434 PMID:29146883 PMID:29365323 PMID:29666006 PMID:30990344 PMID:31064749 PMID:32581362 NCBI chr11:32,765,147...33,003,061
Ensembl chr11:32,769,165...33,003,021 		JBrowse link
juvenile myelomonocytic leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap12 A-kinase anchoring protein 12 disease_progression ISO RGD PMID:26891149 RGD:14348967 NCBI chr 1:40,816,130...40,906,582
Ensembl chr 1:40,816,107...40,906,581 		JBrowse link
G Arhgap26 Rho GTPase activating protein 26 ISO ClinVar Annotator: match by OMIM:607785 OMIM
ClinVar		 PMID:10908648 NCBI chr18:31,807,052...32,557,176
Ensembl chr18:31,812,109...32,207,801 		JBrowse link
G Asxl1 ASXL transcriptional regulator 1 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Juvenile myelomonocytic leukemia		 CTD
ClinVar		 PMID:25741868 PMID:26457647 PMID:32581362 NCBI chr 3:148,832,231...148,902,356
Ensembl chr 3:148,837,814...148,900,452 		JBrowse link
G Cbl Cbl proto-oncogene ISO DNA:mutations:cds:
ClinVar Annotator: match by term: Juvenile myelomonocytic leukemia
CTD Direct Evidence: marker/mechanism		 ClinVar
OMIM
CTD		 PMID:19571318 PMID:19620960 PMID:20543203 PMID:20694012 PMID:20955399 PMID:21901340 PMID:22315502 PMID:24033266 PMID:25283271 PMID:25741868 PMID:25939664 PMID:25952305 PMID:26457647 PMID:27609087 PMID:28343148 PMID:28414188 PMID:28492532, PMID:19571318 RGD:11038806 NCBI chr 8:48,481,256...48,564,775
Ensembl chr 8:48,489,036...48,564,722 		JBrowse link
G Csf2 colony stimulating factor 2 treatment ISO CTD Direct Evidence: marker/mechanism CTD PMID:22315502, PMID:9389708 RGD:10449526 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070 		JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:26457647 NCBI chr 6:28,205,375...28,346,052
Ensembl chr 6:28,235,695...28,340,577 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:26457647 NCBI chr 4:77,284,404...77,347,011
Ensembl chr 4:77,284,404...77,347,011 		JBrowse link
G Flt3 Fms related receptor tyrosine kinase 3 ISS OMIM:607785 MouseDO NCBI chr12:9,360,439...9,437,004
Ensembl chr12:9,360,672...9,436,570 		JBrowse link
G Gata2 GATA binding protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26457647 NCBI chr 4:120,129,028...120,142,490
Ensembl chr 4:120,133,713...120,142,488 		JBrowse link
G Jak3 Janus kinase 3 disease_progression ISO CTD Direct Evidence: marker/mechanism CTD PMID:23832011, PMID:23832011 RGD:11069125 NCBI chr16:20,107,471...20,120,678
Ensembl chr16:20,109,200...20,120,668 		JBrowse link
G Kras KRAS proto-oncogene, GTPase ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Juvenile myelomonocytic leukemia		 CTD
ClinVar		 PMID:2278970 PMID:2547513 PMID:3122217 PMID:3627975 PMID:7773929 PMID:8439212 PMID:12460918 PMID:15696205 PMID:15842656 PMID:16361624 PMID:16434492 PMID:16618717 PMID:17332249 PMID:17384584 PMID:17704260 PMID:17910045 PMID:18316791 PMID:18594010 PMID:18794081 PMID:19018267 PMID:19029981 PMID:19047918 PMID:19075190 PMID:19114683 PMID:19255327 PMID:19358724 PMID:19679400 PMID:19773371 PMID:19881948 PMID:20609353 PMID:20805368 PMID:20921462 PMID:20921465 PMID:20949522 PMID:20978259 PMID:21063026 PMID:21079152 PMID:21169357 PMID:21228335 PMID:21398618 PMID:21975775 PMID:22025163 PMID:22235099 PMID:22392911 PMID:22407852 PMID:22499344 PMID:22571758 PMID:22683711 PMID:22722830 PMID:22734028 PMID:22897852 PMID:23014527 PMID:23096712 PMID:23182985 PMID:23325582 PMID:23406027 PMID:24033266 PMID:24558511 PMID:24720724 PMID:25044103 PMID:25157968 PMID:25695684 PMID:25705018 PMID:25741868 PMID:25808193 PMID:26372703 PMID:26457647 PMID:26623049 PMID:28492532 PMID:29298116 PMID:31891627 PMID:32581362 NCBI chr 4:179,482,562...179,515,483
Ensembl chr 4:179,486,105...179,515,558 		JBrowse link
G Nf1 neurofibromin 1 ISO ClinVar Annotator: match by term: Juvenile myelomonocytic leukemia
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by OMIM:607785		 OMIM
ClinVar
CTD		 PMID:1568247 PMID:8264648 PMID:9003501 PMID:9150739 PMID:9180088 PMID:9219873 PMID:9475595 PMID:9639526 PMID:10607834 PMID:10712197 PMID:10726756 PMID:10862084 PMID:10980545 PMID:11857752 PMID:12095621 PMID:12807981 PMID:14722917 PMID:15146469 PMID:15846561 PMID:16380919 PMID:16513807 PMID:16786508 PMID:16835897 PMID:16961930 PMID:17406642 PMID:18484666 PMID:18546366 PMID:19142971 PMID:21278392 PMID:22155606 PMID:22315502 PMID:22807134 PMID:23244495 PMID:23668869 PMID:23913538 PMID:24033266 PMID:24932921 PMID:25325900 PMID:25403449 PMID:25541118 PMID:25741868 PMID:26056819 PMID:26457647 PMID:26457648 PMID:26467025 PMID:26840085 PMID:27322474 PMID:27716896 PMID:27838393 PMID:28492532 PMID:29290338 PMID:29415745 PMID:29673180 PMID:31595648 PMID:32107864 PMID:32581362 NCBI chr10:66,732,460...66,928,706
Ensembl chr10:66,690,133...66,928,903 		JBrowse link
G Nras NRAS proto-oncogene, GTPase ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Juvenile myelomonocytic leukemia		 CTD
ClinVar		 PMID:2278970 PMID:2407301 PMID:2674680 PMID:2989702 PMID:3122217 PMID:8120410 PMID:10598665 PMID:12460918 PMID:16273091 PMID:16291983 PMID:16434492 PMID:16518851 PMID:17332249 PMID:17384584 PMID:17517660 PMID:17699718 PMID:18375819 PMID:18390968 PMID:18794081 PMID:18948947 PMID:19047918 PMID:19075190 PMID:19657110 PMID:19775298 PMID:19966803 PMID:20130576 PMID:20179705 PMID:20619739 PMID:20736745 PMID:21079152 PMID:21263000 PMID:21305640 PMID:21729679 PMID:21829508 PMID:22144181 PMID:22407852 PMID:22499344 PMID:23414587 PMID:23431193 PMID:23515407 PMID:24284627 PMID:25157968 PMID:26457647 PMID:26619011 PMID:28098151 PMID:28492532 PMID:28594414 NCBI chr 2:205,553,119...205,563,716
Ensembl chr 2:205,553,163...205,560,791 		JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 ISO ClinVar Annotator: match by term: Juvenile myelomonocytic leukemia
DNA:missense mutations:cds:multiple (human)
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by OMIM:607785		 OMIM
ClinVar
CTD		 PMID:11704759 PMID:11992261 PMID:12058348 PMID:12161469 PMID:12161596 PMID:12325025 PMID:12634870 PMID:12717436 PMID:12739139 PMID:12960218 PMID:14634749 PMID:14644997 PMID:14676626 PMID:14961557 PMID:14974085 PMID:14982869 PMID:15001945 PMID:15121796 PMID:15240615 PMID:15248152 PMID:15273746 PMID:15385933 PMID:15389709 PMID:15520399 PMID:15539800 PMID:15604238 PMID:15644411 PMID:15710330 PMID:15712196 PMID:15723289 PMID:15761018 PMID:15834506 PMID:15842656 PMID:15928039 PMID:15929108 PMID:15956085 PMID:15985475 PMID:15987685 PMID:15996221 PMID:16053901 PMID:16078230 PMID:16115145 PMID:16124853 PMID:16263833 PMID:16338218 PMID:16358218 PMID:16377799 PMID:16399795 PMID:16461457 PMID:16498234 PMID:16518851 PMID:16533526 PMID:16638574 PMID:16679933 PMID:16804314 PMID:16990350 PMID:17020470 PMID:17143285 PMID:17177198 PMID:17339163 PMID:17361219 PMID:17497712 PMID:17515436 PMID:17546245 PMID:17661820 PMID:17910045 PMID:17935252 PMID:17972951 PMID:18253957 PMID:18331608 PMID:18372317 PMID:18373317 PMID:18378677 PMID:18470943 PMID:18562489 PMID:18678287 PMID:18758896 PMID:18759865 PMID:18849586 PMID:18854871 PMID:18925961 PMID:19008228 PMID:19020799 PMID:19047918 PMID:19054014 PMID:19077116 PMID:19133693 PMID:19174044 PMID:19179468 PMID:19251646 PMID:19352411 PMID:19509418 PMID:19725129 PMID:19737548 PMID:19768645 PMID:19773259 PMID:19825837 PMID:19835954 PMID:19864201 PMID:20112233 PMID:20308328 PMID:20493809 PMID:20535210 PMID:20651068 PMID:20718194 PMID:20883402 PMID:20954246 PMID:20979190 PMID:21339643 PMID:21340158 PMID:21365175 PMID:21365683 PMID:21407260 PMID:21555152 PMID:21567923 PMID:21590266 PMID:21706501 PMID:21747628 PMID:21901340 PMID:21910245 PMID:21930766 PMID:21934682 PMID:22190897 PMID:22315187 PMID:22315502 PMID:22371576 PMID:22411627 PMID:22420426 PMID:22465605 PMID:22555271 PMID:22585553 PMID:22681964 PMID:22711529 PMID:22781091 PMID:22822385 PMID:22923420 PMID:23312806 PMID:23317994 PMID:23321623 PMID:23334666 PMID:23334668 PMID:23457302 PMID:23513489 PMID:23584145 PMID:23673659 PMID:23726368 PMID:23756559 PMID:23813970 PMID:23825065 PMID:23832011 PMID:24033266 PMID:24037001 PMID:24401936 PMID:24451042 PMID:24628801 PMID:24718990 PMID:24754368 PMID:24767283 PMID:24775816 PMID:24803665 PMID:24820750 PMID:24935154 PMID:25097206 PMID:25326637 PMID:25331952 PMID:25383899 PMID:25395418 PMID:25500235 PMID:25544017 PMID:25585602 PMID:25595571 PMID:25612910 PMID:25731833 PMID:25741868 PMID:25741869 PMID:25884655 PMID:25912702 PMID:25917897 PMID:26084119 PMID:26242988 PMID:26337637 PMID:26457647 PMID:26467025 PMID:26619011 PMID:26673822 PMID:26785492 PMID:26817465 PMID:26822237 PMID:26918529 PMID:27069254 PMID:27153395 PMID:27238887 PMID:27276561 PMID:27484170 PMID:27521173 PMID:27626068 PMID:27659786 PMID:27783593 PMID:28051113 PMID:28098151 PMID:28363362 PMID:28483241 PMID:28492532 PMID:28628100 PMID:28650561 PMID:28681392 PMID:28957739 PMID:29276006 PMID:29493581 PMID:29555671 PMID:29907801 PMID:30311386 PMID:30868567 PMID:32581362 PMID:32860008, PMID:12717436 RGD:11066398 NCBI chr12:40,895,515...40,955,999
Ensembl chr12:40,895,515...40,955,999 		JBrowse link
G Rac2 Rac family small GTPase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26457648 NCBI chr 7:119,769,708...119,797,111
Ensembl chr 7:119,783,849...119,797,098 		JBrowse link
G Rras RAS related ISO CTD Direct Evidence: marker/mechanism CTD PMID:26457647 NCBI chr 1:101,012,822...101,016,720
Ensembl chr 1:101,012,822...101,016,720 		JBrowse link
G Rras2 RAS related 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26457647 NCBI chr 1:178,940,515...179,010,257
Ensembl chr 1:178,940,516...179,010,257 		JBrowse link
G Runx1 RUNX family transcription factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26457647 NCBI chr11:32,765,147...33,003,061
Ensembl chr11:32,769,165...33,003,021 		JBrowse link
G Setbp1 SET binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23832011 PMID:26457647 NCBI chr18:75,090,733...75,432,446
Ensembl chr18:75,095,632...75,207,306 		JBrowse link
G Sh2b3 SH2B adaptor protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26457647 NCBI chr12:40,261,990...40,265,757
Ensembl chr12:40,244,081...40,265,757 		JBrowse link
G Zrsr2 zinc finger (CCCH type), RNA binding motif and serine/arginine rich 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26457647 NCBI chr  X:32,304,707...32,327,419
Ensembl chr  X:32,304,757...32,328,364 		JBrowse link
mast-cell leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kit KIT proto-oncogene receptor tyrosine kinase ISO ClinVar Annotator: match by term: Mast cell leukemia ClinVar PMID:7479840 PMID:7691885 PMID:8589724 PMID:9827716 PMID:9990072 PMID:11380399 PMID:11493470 PMID:15972446 PMID:16352739 PMID:16384925 PMID:16731599 PMID:16912224 PMID:17259998 PMID:18024392 PMID:18986703 PMID:19164557 PMID:19262599 PMID:19865100 PMID:21689725 PMID:22504184 PMID:23582185 PMID:23714533 PMID:24045550 PMID:25157968 PMID:25741868 PMID:26158763 PMID:26822237 PMID:27777718 PMID:28492532 NCBI chr14:35,072,131...35,149,638
Ensembl chr14:35,072,108...35,149,610 		JBrowse link
Monosomy 7 Myelodysplasia and Leukemia Syndrome 2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Samd9 sterile alpha motif domain containing 9 ISO ClinVar Annotator: match by term: MONOSOMY 7 MYELODYSPLASIA AND LEUKEMIA SYNDROME 2 OMIM
ClinVar		 PMID:2569483 PMID:28487541 PMID:30046003 NCBI chr 4:28,304,967...28,324,637
Ensembl chr 4:28,305,002...28,310,178 		JBrowse link
myeloid leukemia associated with Down Syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway ISO ClinVar Annotator: match by term: Myeloid Leukemia Associated with Down Syndrome ClinVar PMID:24033266 PMID:24448499 PMID:24618431 PMID:25186627 PMID:25741868 PMID:25980754 PMID:26467025 PMID:26845104 PMID:27930734 PMID:28492532 PMID:31422818 NCBI chr18:27,011,710...27,106,323
Ensembl chr18:27,047,382...27,105,531 		JBrowse link
G Ctcf CCCTC-binding factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:24056718 NCBI chr19:37,600,151...37,649,674
Ensembl chr19:37,600,148...37,649,673 		JBrowse link
G Dcaf7 DDB1 and CUL4 associated factor 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24056718 NCBI chr10:94,231,585...94,254,046
Ensembl chr10:94,231,585...94,254,046 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:24056718 NCBI chr 4:77,284,404...77,347,011
Ensembl chr 4:77,284,404...77,347,011 		JBrowse link
G Gata1 GATA binding protein 1 ISO ClinVar Annotator: match by term: Leukemia, megakaryoblastic, of Down syndrome ClinVar PMID:12172547, PMID:14636651 RGD:10450612 NCBI chr  X:15,273,937...15,281,759
Ensembl chr  X:15,378,789...15,382,066 		JBrowse link
G Kansl1 KAT8 regulatory NSL complex subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24056718 NCBI chr10:92,388,045...92,517,449
Ensembl chr10:92,389,530...92,476,109 		JBrowse link
G Nras NRAS proto-oncogene, GTPase ISO CTD Direct Evidence: marker/mechanism CTD PMID:24056718 NCBI chr 2:205,553,119...205,563,716
Ensembl chr 2:205,553,163...205,560,791 		JBrowse link
G Rad21 RAD21 cohesin complex component ISO CTD Direct Evidence: marker/mechanism CTD PMID:24056718 NCBI chr 7:91,511,755...91,538,673
Ensembl chr 7:91,511,756...91,538,673 		JBrowse link
G Stag2 stromal antigen 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24056718 NCBI chr  X:128,493,603...128,624,418
Ensembl chr  X:128,493,614...128,624,418 		JBrowse link
G Tp53 tumor protein p53 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24056718 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449 		JBrowse link
Myeloid Leukemia, Accelerated Phase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmi1 BMI1 proto-oncogene, polycomb ring finger ISO CTD Direct Evidence: marker/mechanism CTD PMID:24571310 NCBI chr17:85,360,439...85,370,283
Ensembl chr17:85,364,483...85,368,208 		JBrowse link
G Mir150 microRNA 150 ISO miRNA:decreased expression:leukocytes RGD PMID:21501493 RGD:13782140 NCBI chr 1:101,115,974...101,116,058
Ensembl chr 1:101,115,974...101,116,058 		JBrowse link
Myeloid Leukemia, Chronic-Phase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase disease_progression ISO DNA:hypermethylation:promoter RGD PMID:19344397, PMID:11559572 RGD:11038809, RGD:11038811 NCBI chr 3:10,041,820...10,145,076
Ensembl chr 3:10,041,826...10,144,388 		JBrowse link
G Bcr BCR activator of RhoGEF and GTPase disease_progression ISO RGD PMID:19344397 RGD:11038809 NCBI chr20:14,421,250...14,546,406
Ensembl chr20:14,421,141...14,545,772 		JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 treatment ISO DNA:polymorphism:intron :6986A>G(human) RGD PMID:23394475 RGD:11353797 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399 		JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit treatment ISO DNA:SNP: :rs11615 (human) RGD PMID:22821389 RGD:11252165 NCBI chr 1:80,256,973...80,268,198
Ensembl chr 1:80,256,973...80,268,198 		JBrowse link
G Gfi1 growth factor independent 1 transcriptional repressor disease_progression ISO mRNA,protein:increased expression:mononuclea cell, CD34+ cell RGD PMID:19887785, PMID:23411466 RGD:11040457, RGD:11040461 NCBI chr14:3,058,035...3,073,332
Ensembl chr14:3,058,993...3,068,371 		JBrowse link
G Gfi1b growth factor independent 1B transcriptional repressor ISO mRNA:increased expression:blood: RGD PMID:19360458 RGD:11040460 NCBI chr 3:7,190,721...7,203,444
Ensembl chr 3:7,190,722...7,203,420 		JBrowse link
myeloid sarcoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccr2 C-C motif chemokine receptor 2 ISO associated with Leukemia, Myeloid, Acute;protein:increased expression:blood, leukocyte RGD PMID:20582977 RGD:8661751
G Kras KRAS proto-oncogene, GTPase ISO associated with Leukemia, Myeloid, Acute;DNA:missense mutation:exon:p.G12C (human) RGD PMID:23564351 RGD:11060142 NCBI chr 4:179,482,562...179,515,483
Ensembl chr 4:179,486,105...179,515,558 		JBrowse link
G Pdgfra platelet derived growth factor receptor alpha treatment ISO RGD PMID:22348015 RGD:11075098 NCBI chr14:35,527,926...35,581,130
Ensembl chr14:35,527,927...35,581,031 		JBrowse link
myeloproliferative disorder with eosinophilia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfrb platelet derived growth factor receptor beta ISO OMIM NCBI chr18:56,364,586...56,406,381
Ensembl chr18:56,364,620...56,406,381 		JBrowse link
Noonan Syndrome-Like Disorder with or without Juvenile Myelomonocytic Leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbl Cbl proto-oncogene ISO ClinVar Annotator: match by term: Noonan syndrome-like disorder with juvenile myelomonocytic leukemia
ClinVar Annotator: match by term: Noonan syndrome-like disorder with or without juvenile myelomonocytic leukemia
ClinVar Annotator: match by OMIM:613563		 OMIM
ClinVar		 PMID:17446348 PMID:18698078 PMID:19387008 PMID:19571318 PMID:19620960 PMID:19901108 PMID:20543203 PMID:20595524 PMID:20619386 PMID:20694012 PMID:20951944 PMID:21828135 PMID:22246246 PMID:22733026 PMID:23690417 PMID:23696637 PMID:23823657 PMID:24033266 PMID:24458550 PMID:24728327 PMID:24896146 PMID:25178484 PMID:25224413 PMID:25283271 PMID:25358541 PMID:25731833 PMID:25741868 PMID:25939664 PMID:25952305 PMID:27069254 PMID:28414188 PMID:28492532 PMID:28589114 PMID:29296819 NCBI chr 8:48,481,256...48,564,775
Ensembl chr 8:48,489,036...48,564,722 		JBrowse link
G Mcam melanoma cell adhesion molecule ISO ClinVar Annotator: match by term: Noonan syndrome-like disorder with or without juvenile myelomonocytic leukemia ClinVar NCBI chr 8:48,472,824...48,481,005
Ensembl chr 8:48,472,824...48,481,001 		JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 ISO ClinVar Annotator: match by term: Noonan syndrome-like disorder with or without juvenile myelomonocytic leukemia ClinVar PMID:11992261 PMID:12058348 PMID:12161596 PMID:14634749 PMID:15121796 PMID:15389709 PMID:15520399 PMID:16053901 PMID:16358218 PMID:16377799 PMID:16638574 PMID:16679933 PMID:17020470 PMID:18372317 PMID:18849586 PMID:19725129 PMID:19768645 PMID:20308328 PMID:21339643 PMID:21747628 PMID:22681964 PMID:22822385 PMID:23673659 PMID:24033266 PMID:24401936 PMID:24775816 PMID:24820750 PMID:24935154 PMID:25731833 PMID:25741868 PMID:25917897 PMID:26337637 PMID:26918529 PMID:28483241 PMID:28492532 PMID:29276006 PMID:30311386 NCBI chr12:40,895,515...40,955,999
Ensembl chr12:40,895,515...40,955,999 		JBrowse link
Therapy-related Acute Myeloid Leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2l10 BCL2 like 10 susceptibility ISO DNA:SNP:cds:p.Leu21Arg rs2231292)(human) RGD PMID:24047476 RGD:11058140 NCBI chr 8:82,288,705...82,294,750
Ensembl chr 8:82,288,705...82,294,744 		JBrowse link
G Gstt1 glutathione S-transferase theta 1 susceptibility ISO associated with neoplasms; RGD PMID:17367411 RGD:10450873 NCBI chr20:13,799,102...13,816,527
Ensembl chr20:13,799,102...13,816,526 		JBrowse link
G Klf1 Kruppel like factor 1 ISO RGD PMID:12417757 RGD:10769345 NCBI chr19:26,016,289...26,019,557
Ensembl chr19:26,016,382...26,019,553 		JBrowse link
G Runx1 RUNX family transcription factor 1 ISO DNA:translocations:intron:multiple RGD PMID:9763573 RGD:11251709 NCBI chr11:32,765,147...33,003,061
Ensembl chr11:32,769,165...33,003,021 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16123
    disease of cellular proliferation 5907
      Neoplasms by Histologic Type 3699
        leukemia 582
          myeloid leukemia 376
            Acute Myelomonocytic Leukemia 7
            Myeloid Tumor Suppressor 0
            acute myeloid leukemia + 303
            atypical chronic myeloid leukemia 2
            chronic myeloid leukemia + 86
            chronic myelomonocytic leukemia + 8
            familial chronic myelocytic leukemia-like syndrome 1
            juvenile myelomonocytic leukemia + 22
            monocytic leukemia + 5
            myeloid sarcoma + 3
            subacute myeloid leukemia 0
Path 2
Term Annotations click to browse term
  disease 16123
    disease of anatomical entity 15370
      Hemic and Lymphatic Diseases 2065
        hematopoietic system disease 1647
          Hematologic Neoplasms 839
            hematologic cancer 839
              leukemia 582
                myeloid leukemia 376
                  Acute Myelomonocytic Leukemia 7
                  Myeloid Tumor Suppressor 0
                  acute myeloid leukemia + 303
                  atypical chronic myeloid leukemia 2
                  chronic myeloid leukemia + 86
                  chronic myelomonocytic leukemia + 8
                  familial chronic myelocytic leukemia-like syndrome 1
                  juvenile myelomonocytic leukemia + 22
                  monocytic leukemia + 5
                  myeloid sarcoma + 3
                  subacute myeloid leukemia 0
paths to the root