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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:acute disseminated encephalomyelitis
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Accession:DOID:639 term browser browse the term
Definition:An encephalomyelitis characterized by inflammation located in brain and located in spinal cord that damages myelin. It usually occurs after viral infection, but also following vaccination, bacterial or parasitic infection. (DO)
Synonyms:exact_synonym: ADEM;   acute disseminated encephalitis;   acute disseminated encephalomyelitides;   postexanthem encephalomyelitis;   postinfectious encephalomyelitis
 primary_id: MESH:D004673
 xref: EFO:0007130;   GARD:8639;   NCI:C34578
For additional species annotation, visit the Alliance of Genome Resources.


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acute disseminated encephalomyelitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma disease_progression ISO protein:increased expression:T cell: RGD PMID:11063842 RGD:8157598 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Nefl neurofilament light chain disease_progression ISO protein:increased expresssion:serum (human) RGD PMID:31383792 RGD:127284875 NCBI chr15:42,301,920...42,305,793
Ensembl chr15:42,301,916...42,305,793 		JBrowse link
G RT1-Bb RT1 class II, locus Bb susceptibility ISO DNA:polymorphism (human)
DNA:polymorphism, haplotype: :		 RGD PMID:19722042 PMID:22786832 RGD:5147662, RGD:36049763 NCBI chr20:4,596,558...4,602,201
Ensembl chr20:4,596,559...4,607,597 		JBrowse link
G RT1-Db1 RT1 class II, locus Db1 susceptibility ISO DNA:polymorphisms (human)
DNA:polymorphism, haplotype: :		 RGD PMID:19722042 PMID:22786832 RGD:5147662, RGD:36049763 NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 18976
    disease by infectious agent 2215
      viral infectious disease 1677
        acute disseminated encephalomyelitis 4
          acute hemorrhagic leukoencephalitis 0
          post-vaccinal encephalitis 0
Path 2
Term Annotations click to browse term
  disease 18976
    disease of anatomical entity 18260
      Immune & Inflammatory Diseases 5574
        immune system disease 4782
          primary immunodeficiency disease 4152
            autoimmune disease 2325
              autoimmune disease of the nervous system 672
                autoimmune disease of central nervous system 385
                  Demyelinating Autoimmune Diseases, CNS 378
                    acute disseminated encephalomyelitis 4
                      acute hemorrhagic leukoencephalitis 0
                      post-vaccinal encephalitis 0
paths to the root