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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:estrogen-receptor positive breast cancer
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Accession:DOID:0060075 term browser browse the term
Definition:A breast cancer that is characterized by the presence of estrogen receptors. (DO)
Synonyms:primary_id: RDO:9001776
 xref: EFO:1000649


show annotations for term's descendants           Sort by:
estrogen-receptor positive breast cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam28 ADAM metallopeptidase domain 28 ISO DNA:hypermethylation: RGD PMID:25620615 RGD:153298970 NCBI chr15:43,774,463...43,840,726
Ensembl chr15:42,944,467...43,840,672 		JBrowse link
G Carm1 coactivator-associated arginine methyltransferase 1 disease_progression ISO protein:increased expression:breast: RGD PMID:23887673 RGD:9586721 NCBI chr 8:20,097,262...20,141,950
Ensembl chr 8:20,097,254...20,147,689 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha treatment ISO DNA:mutations:plasma: RGD PMID:28881720 RGD:14402408 NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19137
    disease of cellular proliferation 7889
      Neoplasms by Site 7331
        organ system cancer 5468
          breast cancer 905
            estrogen-receptor positive breast cancer 3
Path 2
Term Annotations click to browse term
  disease 19137
    disease of anatomical entity 18450
      nervous system disease 14357
        Neurologic Manifestations 10449
          sensory system disease 7376
            skin disease 4320
              breast disease 1558
                Breast Neoplasms 1546
                  breast cancer 905
                    estrogen-receptor positive breast cancer 3
paths to the root