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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:6780 term browser browse the term
Definition:A phenothiazine substituted at position 2 (para to the S atom) by a methylsulfinyl group, and on the nitrogen by a 2-(1-methylpiperidin-2-yl)ethyl group.
Synonyms:exact_synonym: 10-[2-(1-methylpiperidin-2-yl)ethyl]-2-(methylsulfinyl)-10H-phenothiazine
 related_synonym: 10-(2-(1-Methyl-2-piperidyl)ethyl)-2-methylsulfinyl phenothiazine;   2-Methanesulfinyl-10-[2-(1-methyl-piperidin-2-yl)-ethyl]-10H-phenothiazine;   Formula=C21H26N2OS2;   InChI=1S/C21H26N2OS2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(26(2)24)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3;   InChIKey=SLVMESMUVMCQIY-UHFFFAOYSA-N;   SMILES=CN1CCCCC1CCN1c2ccccc2Sc2ccc(cc12)S(C)=O;   TPS-23;   mesoridazina;   mesoridazinum;   thioridazine thiomethyl sulfoxide;   thioridazine-2-sulfoxide
 alt_id: CHEBI:248004
 xref: CAS:5588-33-0;   DrugBank:DB00933;   Drug_Central:1712;   KEGG:C07143;   KEGG:D02671;   LINCS:LSM-1329
 xref_mesh: MESH:D008653
 xref: Patent:US3084161;   Reaxys:1033986;   Wikipedia:Mesoridazine

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mesoridazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Mesoridazine results in decreased activity of KCNH2 protein CTD PMID:17042915 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
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  CHEBI ontology 19795
    role 19746
      biological role 19746
        pharmacological role 18832
          neurotransmitter agent 16450
            dopaminergic agent 5110
              dopaminergic antagonist 1196
                mesoridazine 1
                  mesoridazine besylate 0
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  CHEBI ontology 19795
    subatomic particle 19794
      composite particle 19794
        hadron 19794
          baryon 19794
            nucleon 19794
              atomic nucleus 19794
                atom 19794
                  main group element atom 19693
                    main group molecular entity 19693
                      s-block molecular entity 19474
                        hydrogen molecular entity 19466
                          hydrides 18830
                            inorganic hydride 17688
                              pnictogen hydride 17668
                                nitrogen hydride 17540
                                  azane 17273
                                    ammonia 17272
                                      organic amino compound 17272
                                        tertiary amino compound 8695
                                          mesoridazine 1
                                            mesoridazine besylate 0
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