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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:ortho-fused bicyclic arene
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Accession:CHEBI:35426 term browser browse the term
Synonyms:related_synonym: ortho-fused bicyclic arenes


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propranolol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRB2 adrenoceptor beta 2 multiple interactions EXP [Propranolol binds to and results in decreased activity of ADRB2 protein] which results in decreased secretion of Norepinephrine CTD PMID:2884805 NCBI chr 4:60,048,502...60,050,447
Ensembl chr 4:59,941,517...60,050,298 		JBrowse link
G NPPA natriuretic peptide A increases expression EXP Propranolol results in increased expression of NPPA protein CTD PMID:2566282 NCBI chr 2:84,406,317...84,408,115
Ensembl chr 2:84,396,073...84,408,385 		JBrowse link
G REN renin multiple interactions
decreases activity		 EXP Propranolol inhibits the reaction [Isoproterenol results in increased activity of REN protein]
Propranolol results in decreased activity of REN protein		 CTD PMID:2566282 PMID:6103674 NCBI chr38:744,540...766,998
Ensembl chr38:744,614...755,012 		JBrowse link
G VIP vasoactive intestinal peptide decreases expression EXP Propranolol results in decreased expression of VIP protein CTD PMID:2566282 NCBI chr 1:42,941,655...42,950,160
Ensembl chr 1:42,941,224...42,950,700 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 499
    role 499
      biological role 499
        aetiopathogenetic role 397
          carcinogenic agent 30
            polycyclic arene 8
              ortho-fused polycyclic arene 8
                ortho-fused bicyclic arene 4
                  1H-indene + 0
                  azulene + 0
                  naphthalene + 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 499
    subatomic particle 499
      composite particle 499
        hadron 499
          baryon 499
            nucleon 499
              atomic nucleus 499
                atom 499
                  main group element atom 492
                    main group molecular entity 492
                      s-block molecular entity 437
                        hydrogen molecular entity 436
                          hydrides 365
                            organic hydride 71
                              organic fundamental parent 71
                                hydrocarbon 49
                                  cyclic hydrocarbon 25
                                    arene 24
                                      polycyclic arene 8
                                        ortho-fused polycyclic arene 8
                                          ortho-fused bicyclic arene 4
                                            1H-indene + 0
                                            azulene + 0
                                            naphthalene + 4
paths to the root