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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Cacalol
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Accession:CHEBI:137832 term browser browse the term
Synonyms:related_synonym: Formula=C15H16O2;   InChI=1S/C15H16O2/c1-8-5-4-6-11-12(8)10(3)13-9(2)7-17-15(13)14(11)16/h4,6-8,16H,5H2,1-3H3/t8-/m0/s1;   InChIKey=FODSYHRFMKIVST-QMMMGPOBSA-N;   SMILES=C=1C[C@@H](C2=C(C1)C(=C3C(=C2C)C(=CO3)C)O)C
 xref: LIPID_MAPS_instance:LMPR0103300001
 xref_mesh: MESH:C497192


show annotations for term's descendants           Sort by:
Cacalol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation ISO cacalol results in decreased phosphorylation of AKT1 protein CTD PMID:20665104 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Casp3 caspase 3 increases activity ISO cacalol results in increased activity of CASP3 protein CTD PMID:20665104 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Dapk2 death-associated protein kinase 2 increases expression ISO cacalol results in increased expression of DAPK2 mRNA CTD PMID:20665104 NCBI chr 8:66,706,536...66,825,567
Ensembl chr 8:66,706,609...66,825,567 		JBrowse link
G Fas Fas cell surface death receptor multiple interactions
decreases expression		 ISO [Cyclophosphamide co-treated with cacalol] results in decreased expression of FAS protein; cacalol inhibits the reaction [Hydrogen Peroxide results in increased expression of FAS mRNA]; cacalol inhibits the reaction [SREBF1 protein binds to FAS promoter]; cacalol promotes the reaction [Paclitaxel results in decreased expression of FAS mRNA]; Paclitaxel promotes the reaction [cacalol results in decreased expression of FAS mRNA]
cacalol results in decreased expression of FAS mRNA; cacalol results in decreased expression of FAS protein		 CTD PMID:20665104 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 decreases expression
multiple interactions		 ISO cacalol results in decreased expression of SREBF1 protein
cacalol inhibits the reaction [SREBF1 protein binds to FAS promoter]		 CTD PMID:20665104 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19838
    chemical entity 19836
      atom 19836
        nonmetal atom 19774
          carbon atom 19731
            organic molecular entity 19731
              isoprenoid 14069
                terpenoid 13768
                  sesquiterpenoid 3271
                    Cacalol 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19838
    subatomic particle 19836
      composite particle 19836
        hadron 19836
          baryon 19836
            nucleon 19836
              atomic nucleus 19836
                atom 19836
                  main group element atom 19786
                    main group molecular entity 19786
                      s-block molecular entity 19624
                        hydrogen molecular entity 19611
                          hydrides 19117
                            organic hydride 18687
                              organic fundamental parent 18687
                                hydrocarbon 18432
                                  terpene 14069
                                    sesquiterpene 3271
                                      sesquiterpenoid 3271
                                        Cacalol 5
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