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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:sufentanil
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Accession:CHEBI:9316 term browser browse the term
Definition:An anilide resulting from the formal condensation of the aryl amino group of 4-(methoxymethyl)-N-phenyl-1-[2-(2-thienyl)ethyl]piperidin-4-amine with propanoic acid.
Synonyms:exact_synonym: N-{4-(methoxymethyl)-1-[2-(2-thienyl)ethyl]piperidin-4-yl}-N-phenylpropanamide
 related_synonym: Formula=C22H30N2O2S;   InChI=1S/C22H30N2O2S/c1-3-21(25)24(19-8-5-4-6-9-19)22(18-26-2)12-15-23(16-13-22)14-11-20-10-7-17-27-20/h4-10,17H,3,11-16,18H2,1-2H3;   InChIKey=GGCSSNBKKAUURC-UHFFFAOYSA-N;   N-(4-(Methoxymethyl)-1-(2-(2-thienyl)ethyl)-4-piperidinyl)-N-phenylpropanamide;   N-(4-(Methoxymethyl)-1-(2-(2-thienyl)ethyl)-4-piperidyl)propionanilide;   SMILES=CCC(=O)N(c1ccccc1)C1(CCN(CCc2cccs2)CC1)COC;   Sufentanyl;   sufentanilum
 xref: CAS:56030-54-7;   DrugBank:DB00708;   Drug_Central:2491;   HMDB:HMDB0014846;   KEGG:C08022;   KEGG:D05938
 xref_mesh: MESH:D017409
 xref: PMID:10628901;   PMID:10945855;   PMID:11137863;   PMID:11504823;   PMID:15475572;   PMID:15828831;   PMID:16621415;   PMID:17118343;   PMID:9580589;   Patent:DE2610228;   Patent:US3998834;   Reaxys:499558;   Wikipedia:Sufentanil


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sufentanil term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr3a 5-hydroxytryptamine receptor 3A affects activity ISO Sufentanil affects the activity of HTR3A protein CTD PMID:18635474 NCBI chr 8:49,242,018...49,254,475
Ensembl chr 8:49,242,020...49,254,389 		JBrowse link
G Pomc proopiomelanocortin decreases expression ISO Sufentanil results in decreased expression of POMC protein modified form CTD PMID:15714323 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19841
    role 19817
      biological role 19815
        pharmacological role 19058
          analgesic 14740
            opioid analgesic 668
              sufentanil 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19841
    subatomic particle 19839
      composite particle 19839
        hadron 19839
          baryon 19839
            nucleon 19839
              atomic nucleus 19839
                atom 19839
                  main group element atom 19789
                    main group molecular entity 19789
                      s-block molecular entity 19626
                        hydrogen molecular entity 19613
                          hydrides 19120
                            inorganic hydride 18118
                              pnictogen hydride 18107
                                nitrogen hydride 18014
                                  azane 17824
                                    ammonia 17823
                                      organic amino compound 17823
                                        primary amino compound 9311
                                          primary amine 6327
                                            primary arylamine 3644
                                              aniline 3482
                                                anilide 1104
                                                  sufentanil 2
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