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hydroxyindoles - Ontology Report - Rat Genome Database

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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:hydroxyindoles
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Accession:CHEBI:84729 term browser browse the term
Definition:Any member of the class of indoles carrying at least one hydroxy group.

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show annotations for term's descendants           Sort by:
indoxyl sulfate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC22A6 solute carrier family 22 member 6 multiple interactions EXP [Lansoprazole results in decreased activity of SLC22A6 protein] which results in decreased uptake of Indican; [Omeprazole results in decreased activity of SLC22A6 protein] which results in decreased uptake of Indican; [Pantoprazole results in decreased activity of SLC22A6 protein] which results in decreased uptake of Indican CTD PMID:36243147 NCBI chr18:53,736,669...53,745,001
Ensembl chr18:53,736,959...53,744,396 		JBrowse link
serotonin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen increases response to substance
multiple interactions 		EXP AGT protein modified form results in increased susceptibility to Serotonin
Deferoxamine inhibits the reaction [AGT protein modified form results in increased susceptibility to Serotonin]; Reactive Oxygen Species inhibits the reaction [AGT protein modified form results in increased susceptibility to Serotonin] 		CTD PMID:8021468 NCBI chr 4:8,681,192...8,694,059
Ensembl chr 4:8,683,798...8,693,880 		JBrowse link
G EDN1 endothelin 1 increases activity EXP Serotonin results in increased activity of EDN1 protein CTD PMID:9918753 NCBI chr35:11,808,892...11,815,383
Ensembl chr35:11,808,892...11,815,383 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 1274
    chemical entity 1274
      molecular entity 1274
        polyatomic entity 1267
          heteroatomic molecular entity 1222
            hydroxides 1201
              organic hydroxy compound 929
                hydroxyindoles 3
                  (2E)-N-\{2-[5,5'-dihydroxy-3'-(2-\{[(2E)-1-hydroxy-3-(4-hydroxy-3-methoxyphenyl)prop-2-en-1-ylidene]amino\}ethyl)-1H,1'H-[4,4'-biindole]-3-yl]ethyl\}-3-(4-hydroxy-3-methoxyphenyl)prop-2-enimidic acid 0
                  (2E)-N-\{2-[5,5'-dihydroxy-3'-(2-\{[(2E)-1-hydroxy-3-(4-hydroxy-3-methoxyphenyl)prop-2-en-1-ylidene]amino\}ethyl)-1H,1'H-[4,4'-biindole]-3-yl]ethyl\}-3-(4-hydroxyphenyl)prop-2-enimidic acid 0
                  (2R,3R,4R,5S)-6-\{[7-carbamoyl-5-hydroxy-1-(4-phenylbutan-2-yl)indol-6-yl]oxy\}-3,4,5-trihydroxyoxane-2-carboxylic acid 0
                  (2R,3R,4R,5S)-6-\{[7-carbamoyl-6-hydroxy-1-(4-phenylbutan-2-yl)indol-5-yl]oxy\}-3,4,5-trihydroxyoxane-2-carboxylic acid 0
                  (4R)-2-[(5-hydroxy-1H-indol-3-yl)methyl]-4-thiazolidinecarboxylic acid 0
                  (5-hydroxyindol-3-yl)acetaldehyde 0
                  (E,E)-4,4''-Bi(N-4-hydroxycinnamoylserotonin) 0
                  2,2,2-trideuterio-N-[1,1,2,2-tetradeuterio-2-(5-hydroxy-1H-indol-3-yl)ethyl]acetamide 0
                  2-(8-methoxy-4-methyl-1-oxo-[1,2,4]triazino[4,5-a]indol-2-yl)-N-(3-propan-2-yloxypropyl)acetamide 0
                  2-Octadecyl-1H-indol-3-ol 0
                  2-hydroxy-(indol-3-yl)acetic acid 0
                  2-hydroxyindole 0
                  2-hydroxymelatonin 0
                  3-(1-methyl-4-piperidinyl)-1H-indol-5-ol 0
                  3-(5-hydroxyindol-3-yl)pyruvic acid 0
                  3-Formyl-6-hydroxyindole 0
                  3-hydroxy-3-methyloxindole 0
                  3-hydroxyindolin-2-one 0
                  4-Hydroxy-1H-indole-3-acetonitrile 0
                  4-hydroxy-indole-3-carbonyl nitrile 0
                  4-hydroxyindole 0
                  4-hydroxyindole-3-carbaldehyde 0
                  4-hydroxytryptamine 0
                  5,5',6,6'-tetrahydroxy-3,3'-biindolyl 0
                  5,6-dihydroxy-1-(4-phenylbutan-2-yl)indole-7-carboxamide 0
                  5-bromo-3-hydroxyindole 0
                  5-bromo-4-chloro-3-hydroxyindole 0
                  5-bromometagenediindole B 0
                  5-bromometagenediindole C 0
                  5-hydroxyindole 0
                  5-hydroxyindoleacetylglycine 0
                  6-Hydroxy-1H-indole-3-acetamide 0
                  6-hydroxy-N-acetyl-beta-oxotryptamine 0
                  7-hydroxyindole sulfate 0
                  AZD1080 0
                  Birnbaumin A 0
                  C.I. Pigment Blue 63 0
                  Hydroxysattazolin 0
                  Indigo dye 0
                  LSM-17205 0
                  LSM-19897 0
                  LSM-32074 0
                  Me-YTM-T 0
                  N-(1,3-benzodioxol-5-yl)-2-[(8-methoxy-5H-[1,2,4]triazino[5,6-b]indol-3-yl)thio]acetamide 0
                  N-(2-hydroxy-5-methoxy-1H-indol-3-yl)acetamide 0
                  N-[(6-hydroxyindol-3-yl)acetyl]phenylalanine 0
                  N-acetylindoxyl 0
                  N-acylserotonin + 0
                  N-arachidonoyl-2-oxoserotonin 0
                  N-feruloylserotonin 0
                  N6-cis-p-Coumaroylserotonin 0
                  YTM-T 0
                  bromotopsentin 0
                  deoxyviolaceinic acid 0
                  dihydroxyindole + 0
                  dopaminechrome (enol form) 0
                  indoxyl + 1
                  notoamide S + 0
                  protoviolaceinic acid 0
                  proviolacein + 0
                  psilocin + 0
                  serotonin + 2
                  torkinib 0
                  violacein 0
                  violaceinic acid 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 1274
    subatomic particle 1274
      composite particle 1274
        hadron 1274
          baryon 1274
            nucleon 1274
              atomic nucleus 1274
                atom 1274
                  main group element atom 1267
                    p-block element atom 1267
                      carbon group element atom 1257
                        carbon atom 1256
                          organic molecular entity 1256
                            organic molecule 1245
                              organic cyclic compound 1229
                                organic heterocyclic compound 417
                                  organic heteropolycyclic compound 95
                                    organic heterobicyclic compound 44
                                      benzopyrrole 8
                                        indoles 8
                                          hydroxyindoles 3
                                            (2E)-N-\{2-[5,5'-dihydroxy-3'-(2-\{[(2E)-1-hydroxy-3-(4-hydroxy-3-methoxyphenyl)prop-2-en-1-ylidene]amino\}ethyl)-1H,1'H-[4,4'-biindole]-3-yl]ethyl\}-3-(4-hydroxy-3-methoxyphenyl)prop-2-enimidic acid 0
                                            (2E)-N-\{2-[5,5'-dihydroxy-3'-(2-\{[(2E)-1-hydroxy-3-(4-hydroxy-3-methoxyphenyl)prop-2-en-1-ylidene]amino\}ethyl)-1H,1'H-[4,4'-biindole]-3-yl]ethyl\}-3-(4-hydroxyphenyl)prop-2-enimidic acid 0
                                            (2R,3R,4R,5S)-6-\{[7-carbamoyl-5-hydroxy-1-(4-phenylbutan-2-yl)indol-6-yl]oxy\}-3,4,5-trihydroxyoxane-2-carboxylic acid 0
                                            (2R,3R,4R,5S)-6-\{[7-carbamoyl-6-hydroxy-1-(4-phenylbutan-2-yl)indol-5-yl]oxy\}-3,4,5-trihydroxyoxane-2-carboxylic acid 0
                                            (4R)-2-[(5-hydroxy-1H-indol-3-yl)methyl]-4-thiazolidinecarboxylic acid 0
                                            (5-hydroxyindol-3-yl)acetaldehyde 0
                                            (E,E)-4,4''-Bi(N-4-hydroxycinnamoylserotonin) 0
                                            2,2,2-trideuterio-N-[1,1,2,2-tetradeuterio-2-(5-hydroxy-1H-indol-3-yl)ethyl]acetamide 0
                                            2-(8-methoxy-4-methyl-1-oxo-[1,2,4]triazino[4,5-a]indol-2-yl)-N-(3-propan-2-yloxypropyl)acetamide 0
                                            2-Octadecyl-1H-indol-3-ol 0
                                            2-hydroxy-(indol-3-yl)acetic acid 0
                                            2-hydroxyindole 0
                                            2-hydroxymelatonin 0
                                            3-(1-methyl-4-piperidinyl)-1H-indol-5-ol 0
                                            3-(5-hydroxyindol-3-yl)pyruvic acid 0
                                            3-Formyl-6-hydroxyindole 0
                                            3-hydroxy-3-methyloxindole 0
                                            3-hydroxyindolin-2-one 0
                                            4-Hydroxy-1H-indole-3-acetonitrile 0
                                            4-hydroxy-indole-3-carbonyl nitrile 0
                                            4-hydroxyindole 0
                                            4-hydroxyindole-3-carbaldehyde 0
                                            4-hydroxytryptamine 0
                                            5,5',6,6'-tetrahydroxy-3,3'-biindolyl 0
                                            5,6-dihydroxy-1-(4-phenylbutan-2-yl)indole-7-carboxamide 0
                                            5-bromo-3-hydroxyindole 0
                                            5-bromo-4-chloro-3-hydroxyindole 0
                                            5-bromometagenediindole B 0
                                            5-bromometagenediindole C 0
                                            5-hydroxyindole 0
                                            5-hydroxyindoleacetylglycine 0
                                            6-Hydroxy-1H-indole-3-acetamide 0
                                            6-hydroxy-N-acetyl-beta-oxotryptamine 0
                                            7-hydroxyindole sulfate 0
                                            AZD1080 0
                                            Birnbaumin A 0
                                            C.I. Pigment Blue 63 0
                                            Hydroxysattazolin 0
                                            Indigo dye 0
                                            LSM-17205 0
                                            LSM-19897 0
                                            LSM-32074 0
                                            Me-YTM-T 0
                                            N-(1,3-benzodioxol-5-yl)-2-[(8-methoxy-5H-[1,2,4]triazino[5,6-b]indol-3-yl)thio]acetamide 0
                                            N-(2-hydroxy-5-methoxy-1H-indol-3-yl)acetamide 0
                                            N-[(6-hydroxyindol-3-yl)acetyl]phenylalanine 0
                                            N-acetylindoxyl 0
                                            N-acylserotonin + 0
                                            N-arachidonoyl-2-oxoserotonin 0
                                            N-feruloylserotonin 0
                                            N6-cis-p-Coumaroylserotonin 0
                                            YTM-T 0
                                            bromotopsentin 0
                                            deoxyviolaceinic acid 0
                                            dihydroxyindole + 0
                                            dopaminechrome (enol form) 0
                                            indoxyl + 1
                                            notoamide S + 0
                                            protoviolaceinic acid 0
                                            proviolacein + 0
                                            psilocin + 0
                                            serotonin + 2
                                            torkinib 0
                                            violacein 0
                                            violaceinic acid 0
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