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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate
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Accession:CHEBI:78734 term browser browse the term
Definition:A tropane alkaloid that is (1R,5)-8-methyl-8-azabicyclo[3.2.1]octane substituted by a (3-hydroxy-2-phenylpropanoyl)oxy group at position 3.
Synonyms:exact_synonym: (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl 3-hydroxy-2-phenylpropanoate
 related_synonym: Formula=C17H23NO3;   InChI=1S/C17H23NO3/c1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12/h2-6,13-16,19H,7-11H2,1H3/t13-,14+,15+,16?;   InChIKey=RKUNBYITZUJHSG-SPUOUPEWSA-N;   SMILES=CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)C(CO)c1ccccc1;   dl-Hyoscyamine
 xref: CAS:51-55-8;   KEGG:C01479;   KEGG:D00113;   KNApSAcK:C00002277
 xref_mesh: MESH:D001285
 cyclic_relationship: is_conjugate_base_of CHEBI:57858


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tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACHE acetylcholinesterase multiple interactions EXP [Obidoxime Chloride co-treated with Atropine] inhibits the reaction [Sarin results in decreased activity of ACHE protein]; [Obidoxime Chloride co-treated with Atropine] inhibits the reaction [Soman results in decreased activity of ACHE protein]; [Obidoxime Chloride co-treated with Atropine] inhibits the reaction [VX results in decreased activity of ACHE protein] CTD PMID:16915560 NCBI chr 6:8,874,747...8,879,926
Ensembl chr 6:8,873,584...8,879,702 		JBrowse link
G SCT secretin multiple interactions EXP Atropine inhibits the reaction [SCT protein results in increased abundance of Bicarbonates] CTD PMID:3562434
atropine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACHE acetylcholinesterase multiple interactions EXP [Obidoxime Chloride co-treated with Atropine] inhibits the reaction [Sarin results in decreased activity of ACHE protein]; [Obidoxime Chloride co-treated with Atropine] inhibits the reaction [Soman results in decreased activity of ACHE protein]; [Obidoxime Chloride co-treated with Atropine] inhibits the reaction [VX results in decreased activity of ACHE protein] CTD PMID:16915560 NCBI chr 6:8,874,747...8,879,926
Ensembl chr 6:8,873,584...8,879,702 		JBrowse link
G SCT secretin multiple interactions EXP Atropine inhibits the reaction [SCT protein results in increased abundance of Bicarbonates] CTD PMID:3562434
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 495
    role 495
      biological role 495
        biochemical role 455
          metabolite 446
            alkaloid 14
              tropane alkaloid 2
                tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate 2
                  (R)-atropine + 2
                  (S)-atropine + 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 495
    subatomic particle 495
      composite particle 495
        hadron 495
          baryon 495
            nucleon 495
              atomic nucleus 495
                atom 495
                  main group element atom 488
                    p-block element atom 488
                      carbon group element atom 477
                        carbon atom 476
                          organic molecular entity 476
                            heteroorganic entity 472
                              organochalcogen compound 426
                                organooxygen compound 424
                                  carbon oxoacid 365
                                    carboxylic acid 365
                                      monocarboxylic acid 90
                                        fatty acid 58
                                          saturated fatty acid 50
                                            propionic acid 4
                                              2-arylpropionic acid 2
                                                hydratropic acid 2
                                                  tropic acid 2
                                                    tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate 2
                                                      (R)-atropine + 2
                                                      (S)-atropine + 2
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