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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:tropane alkaloid
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Accession:CHEBI:37332 term browser browse the term
Synonyms:related_synonym: tropane alkaloids
 alt_id: CHEBI:27154;   CHEBI:27155



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(S)-atropine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Hyoscyamine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
JBrowse link
Anatoxin a term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit multiple interactions EXP anatoxin a inhibits the reaction [iodo-alpha-bungarotoxin binds to CHRNA7 protein] CTD PMID:19448648 NCBI chr 1:116,715,286...116,837,223
Ensembl chr 1:116,714,711...116,837,240
JBrowse link
atropine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions
decreases activity
ISO Atropine inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
Atropine results in decreased activity of ABCB11 protein
CTD PMID:24014644 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase multiple interactions ISO [Parathion co-treated with Atropine] results in increased expression of ABL1 mRNA CTD PMID:17390078 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065
JBrowse link
G Ache acetylcholinesterase multiple interactions ISO
EXP
Atropine inhibits the reaction [[Organophosphorus Compounds results in decreased activity of ACHE protein] which results in increased abundance of Acetylcholine]; Atropine inhibits the reaction [Carbachol results in increased metabolism of and results in increased secretion of ACHE protein]; Atropine inhibits the reaction [Paraoxon results in increased expression of ACHE protein]
[Atropine co-treated with Obidoxime Chloride] inhibits the reaction [Paraoxon results in decreased activity of ACHE protein]; [Methyl Parathion co-treated with pralidoxime co-treated with Atropine] results in decreased expression of ACHE protein; [Paraoxon co-treated with pralidoxime co-treated with Atropine] results in decreased activity of ACHE protein; [pralidoxime co-treated with Atropine] inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; [tariquidar co-treated with asoxime chloride co-treated with Atropine] inhibits the reaction [Soman results in decreased activity of ACHE protein]; Atropine inhibits the reaction [Methyl Parathion results in decreased activity of ACHE protein]; Obidoxime Chloride inhibits the reaction [[Paraoxon co-treated with pralidoxime co-treated with Atropine] results in decreased activity of ACHE protein]; pralidoxime promotes the reaction [[Atropine co-treated with Curcumin] inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]]
[1-(4-hydroxyiminomethylpyridinium)-3-(carbamoylpyridinium) propane dibromide co-treated with Atropine] inhibits the reaction [Sarin results in decreased activity of ACHE protein]; [[1-(4-hydroxyiminomethylpyridinium)-3-(carbamoylpyridinium) propane dibromide co-treated with cucurbit(7)uril] co-treated with Atropine] inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Atropine inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Atropine promotes the reaction [Dichlorvos results in increased phosphorylation of ACHE protein]; Atropine promotes the reaction [haloxon results in increased phosphorylation of ACHE protein]; Atropine promotes the reaction [Paraoxon results in increased phosphorylation of ACHE protein]
CTD PMID:2241428 PMID:10421444 PMID:17963125 PMID:20105433 PMID:21600273 More... NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Adcy5 adenylate cyclase 5 increases response to substance ISO ADCY5 protein results in increased susceptibility to Atropine CTD PMID:12869393 NCBI chr11:65,471,612...65,618,877
Ensembl chr11:65,471,612...65,618,974
JBrowse link
G Aqp5 aquaporin 5 multiple interactions ISO Atropine inhibits the reaction [Pilocarpine affects the localization of AQP5 protein] CTD PMID:26208470 NCBI chr 7:130,722,675...130,726,207
Ensembl chr 7:130,721,748...130,726,209
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions EXP [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman affects the expression of BAX mRNA] CTD PMID:21971501 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcar1 BCAR1 scaffold protein, Cas family member multiple interactions ISO Atropine inhibits the reaction [[oxotremorine M co-treated with wortmannin] inhibits the reaction [oxophenylarsine results in increased phosphorylation of BCAR1 protein]] CTD PMID:10537051 NCBI chr19:39,679,218...39,713,952
Ensembl chr19:39,679,204...39,713,907
JBrowse link
G Bche butyrylcholinesterase multiple interactions EXP
ISO
[Atropine co-treated with pralidoxime] results in decreased expression of BCHE protein; [Methyl Parathion co-treated with pralidoxime co-treated with Atropine] results in decreased expression of BCHE protein
[BCHE protein co-treated with asoxime chloride co-treated with pro-diazepam co-treated with Atropine] results in decreased susceptibility to VX
CTD PMID:17963125 PMID:22981459 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
JBrowse link
G Bdkrb2 bradykinin receptor B2 multiple interactions ISO BDKRB2 affects the susceptibility to [Propranolol co-treated with Atropine] CTD PMID:10614985 NCBI chr 6:124,472,317...124,502,497
Ensembl chr 6:124,472,566...124,502,497
JBrowse link
G Bmp6 bone morphogenetic protein 6 multiple interactions EXP Atropine inhibits the reaction [Carbon Tetrachloride results in increased expression of BMP6 mRNA] CTD PMID:18472332 NCBI chr17:26,318,121...26,469,034
Ensembl chr17:26,318,569...26,470,365
JBrowse link
G Cacna1e calcium voltage-gated channel subunit alpha1 E multiple interactions EXP Atropine inhibits the reaction [Methacholine Chloride affects the reaction [CACNA1E protein results in increased transport of Barium]] CTD PMID:12663092 NCBI chr13:66,574,659...67,063,443
Ensembl chr13:66,581,920...66,894,450
JBrowse link
G Calca calcitonin-related polypeptide alpha affects activity EXP Atropine affects the activity of CALCA protein CTD PMID:7906887 PMID:10075105 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
JBrowse link
G Casp3 caspase 3 increases expression EXP Atropine results in increased expression of CASP3 mRNA CTD PMID:19815060 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions ISO [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of CCL5 mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of CCL5 protein] CTD PMID:22245128 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Ccna1 cyclin A1 increases expression
multiple interactions
ISO Atropine results in increased expression of CCNA1 mRNA
[Parathion co-treated with Atropine] results in increased expression of CCNA1 mRNA
CTD PMID:17390078 NCBI chr 2:139,231,738...139,278,066
Ensembl chr 2:139,201,074...139,243,157
JBrowse link
G Ccnd3 cyclin D3 multiple interactions ISO [Parathion co-treated with Atropine] results in increased expression of CCND3 mRNA CTD PMID:17390078 NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371
JBrowse link
G Ccne1 cyclin E1 increases expression
multiple interactions
ISO Atropine results in increased expression of CCNE1 mRNA
[Parathion co-treated with Atropine] results in increased expression of CCNE1 mRNA
CTD PMID:17390078 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
JBrowse link
G Ccne2 cyclin E2 multiple interactions
increases expression
ISO [Parathion co-treated with Atropine] results in increased expression of CCNE2 mRNA
Atropine results in increased expression of CCNE2 mRNA
CTD PMID:17390078 NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632
JBrowse link
G Cd40 CD40 molecule multiple interactions ISO Atropine inhibits the reaction [Carbachol results in increased expression of CD40 protein] CTD PMID:16879495 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
JBrowse link
G Cdc20 cell division cycle 20 multiple interactions
increases expression
ISO [Parathion co-treated with Atropine] results in increased expression of CDC20 mRNA
Atropine results in increased expression of CDC20 mRNA
CTD PMID:17390078 NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
JBrowse link
G Cdc6 cell division cycle 6 multiple interactions ISO [Parathion co-treated with Atropine] results in increased expression of CDC6 mRNA CTD PMID:17390078 NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011
JBrowse link
G Cdk1 cyclin-dependent kinase 1 multiple interactions
increases expression
ISO [Parathion co-treated with Atropine] results in increased expression of CDK1 mRNA
Atropine results in increased expression of CDK1 mRNA
CTD PMID:17390078 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Ces1d carboxylesterase 1D multiple interactions ISO Atropine inhibits the reaction [CES1 protein results in increased hydrolysis of 4-methylumbelliferyl acetate] CTD PMID:9311626 NCBI chr19:13,873,490...13,912,035 JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 multiple interactions
decreases activity
ISO Atropine binds to and results in decreased activity of CHRM1 protein; Atropine inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]
Atropine results in decreased activity of CHRM1 protein
Atropine affects the reaction [muscarinic toxin 7 binds to CHRM1 protein]
CTD PMID:16439611 PMID:18316702 PMID:31830555 NCBI chr 1:205,567,046...205,583,001
Ensembl chr 1:205,567,220...205,582,356
JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 multiple interactions ISO Atropine binds to and results in decreased activity of CHRM2 protein CTD PMID:15140916 NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103
JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 multiple interactions
decreases activity
ISO Atropine binds to and results in decreased activity of CHRM3 protein; Atropine inhibits the reaction [Carbachol results in increased activity of CHRM3 protein]
Atropine results in decreased activity of CHRM3 protein
CTD PMID:15140916 PMID:20708676 PMID:31830555 NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278
JBrowse link
G Chrm4 cholinergic receptor, muscarinic 4 multiple interactions
affects binding
ISO [WIN 62577 co-treated with Quinuclidinyl Benzilate] inhibits the reaction [Atropine binds to CHRM4 protein] CTD PMID:16709648 NCBI chr 3:77,893,425...77,901,166
Ensembl chr 3:77,893,425...77,901,159
JBrowse link
G Chrm5 cholinergic receptor, muscarinic 5 multiple interactions ISO Atropine inhibits the reaction [Acetylcholine results in increased activity of CHRM5 protein] CTD PMID:31323226 NCBI chr 3:99,284,846...99,337,252
Ensembl chr 3:99,284,846...99,337,252
JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions
affects binding
ISO
EXP
Atropine promotes the reaction [Acetylcholine affects the activity of [CHRNA4 protein binds to CHRNB2 protein]]
Atropine promotes the reaction [Mecamylamine inhibits the reaction [Paraoxon results in decreased expression of CHRNA4 mRNA]]; Atropine promotes the reaction [Mecamylamine inhibits the reaction [Paraoxon results in decreased expression of CHRNA4 protein]]
Atropine binds to [CHRNA4 protein binds to CHRNB2 protein]
CTD PMID:15733544 PMID:21791372 NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957
JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit affects binding
multiple interactions
ISO
EXP
Atropine binds to [CHRNA4 protein binds to CHRNB2 protein]
Atropine promotes the reaction [Mecamylamine inhibits the reaction [Paraoxon results in decreased expression of CHRNB2 mRNA]]; Atropine promotes the reaction [Mecamylamine inhibits the reaction [Paraoxon results in decreased expression of CHRNB2 protein]]
Atropine promotes the reaction [Acetylcholine affects the activity of [CHRNA4 protein binds to CHRNB2 protein]]
CTD PMID:15733544 PMID:21791372 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions EXP [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman affects the phosphorylation of CREB1 protein] CTD PMID:21971501 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Crh corticotropin releasing hormone multiple interactions EXP
ISO
Atropine inhibits the reaction [acephate results in increased expression of CRH mRNA]; Atropine inhibits the reaction [acephate results in increased secretion of CRH protein]; Atropine inhibits the reaction [methamidophos results in increased expression of CRH mRNA]; Atropine inhibits the reaction [methamidophos results in increased secretion of CRH protein]
[Atropine co-treated with SR 140333 co-treated with SR 48968] results in decreased activity of CRH protein
CTD PMID:12039681 PMID:12906840 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of CTNNB1 protein mutant form]; Atropine inhibits the reaction [Parathion results in increased expression of CTNNB1 protein] CTD PMID:17390078 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions ISO [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of CXCL1 mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of CXCL1 protein] CTD PMID:22245128 NCBI chr14:17,270,146...17,289,458
Ensembl chr14:17,270,146...17,289,511
JBrowse link
G Dvl2 dishevelled segment polarity protein 2 multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of DVL2 protein] CTD PMID:17390078 NCBI chr10:54,723,356...54,732,823
Ensembl chr10:54,723,411...54,732,820
JBrowse link
G Edn1 endothelin 1 multiple interactions ISO EDN1 protein results in decreased activity of [Atropine co-treated with Histamine] CTD PMID:12906840 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of EGFR protein] CTD PMID:17390078 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Egr1 early growth response 1 multiple interactions EXP Atropine inhibits the reaction [Pilocarpine results in increased expression of EGR1 mRNA] CTD PMID:7968354 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Egr2 early growth response 2 multiple interactions EXP Atropine inhibits the reaction [Pilocarpine results in increased expression of EGR2 mRNA] CTD PMID:7968354 NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562
JBrowse link
G Ezr ezrin multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of EZR protein] CTD PMID:17390078 NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505
JBrowse link
G F2 coagulation factor II multiple interactions ISO [Paraoxon co-treated with Atropine co-treated with Obidoxime Chloride] results in decreased expression of F2 mRNA; [Paraoxon co-treated with Atropine co-treated with Obidoxime Chloride] results in increased activity of F2 protein CTD PMID:30515700 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
JBrowse link
G F2r coagulation factor II (thrombin) receptor multiple interactions ISO [Paraoxon co-treated with Atropine co-treated with Obidoxime Chloride] results in increased expression of F2R protein CTD PMID:30515700 NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
EXP
ISO
Atropine results in increased expression of FOS protein
Atropine inhibits the reaction [Paraoxon results in increased expression of FOS mRNA]
[asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased expression of FOS protein]; Atropine inhibits the reaction [Pilocarpine results in increased expression of FOS mRNA]
CTD PMID:7968354 PMID:8281324 PMID:21787676 PMID:21971501 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Ghrl ghrelin and obestatin prepropeptide multiple interactions EXP Atropine inhibits the reaction [[Pentobarbital co-treated with L-pyroglutamyl-L-histidyl-3,3-dimethylprolinamide] results in increased expression of GHRL protein] CTD PMID:16959836 NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621
JBrowse link
G Glra1 glycine receptor, alpha 1 multiple interactions ISO Atropine binds to and results in decreased activity of GLRA1 protein CTD PMID:15081878 NCBI chr10:39,625,853...39,727,897
Ensembl chr10:39,629,459...39,727,162
JBrowse link
G Grm4 glutamate metabotropic receptor 4 multiple interactions ISO Atropine inhibits the reaction [[Carbachol results in increased activity of [GRM4 protein binds to KCNJ3 protein]] which results in increased import of Thallium] CTD PMID:18171729 NCBI chr20:5,484,172...5,572,821
Ensembl chr20:5,481,124...5,572,821
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of ICAM1 mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of ICAM1 protein] CTD PMID:22245128 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of IL1B mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of IL1B protein] CTD PMID:22245128 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions ISO [Atropine co-treated with Ketamine] inhibits the reaction [Soman results in increased expression of IL6 mRNA]; [Atropine co-treated with Ketamine] inhibits the reaction [Soman results in increased expression of IL6 protein] CTD PMID:22245128 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman affects the phosphorylation of JUN protein] CTD PMID:21971501 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP Atropine inhibits the reaction [Pilocarpine results in increased expression of JUNB mRNA] CTD PMID:7968354 NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
JBrowse link
G Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3 multiple interactions ISO Atropine inhibits the reaction [[Carbachol results in increased activity of [GRM4 protein binds to KCNJ3 protein]] which results in increased import of Thallium] CTD PMID:18171729 NCBI chr 3:39,944,896...40,106,646
Ensembl chr 3:39,945,351...40,109,124
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of KIT protein] CTD PMID:17390078 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
JBrowse link
G Ltf lactotransferrin multiple interactions ISO Atropine inhibits the reaction [methylcholine results in increased secretion of LTF protein] CTD PMID:11112886 NCBI chr 8:110,999,948...111,022,795
Ensembl chr 8:110,999,948...111,022,795
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK1 protein] CTD PMID:21971501 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions EXP [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK14 protein] CTD PMID:21971501 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK3 protein] CTD PMID:21971501 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions EXP [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK8 protein] CTD PMID:21971501 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mcm4 minichromosome maintenance complex component 4 multiple interactions
increases expression
ISO [Parathion co-treated with Atropine] results in increased expression of MCM4 mRNA
Atropine results in increased expression of MCM4 mRNA
CTD PMID:17390078 NCBI chr11:85,258,443...85,272,144
Ensembl chr11:85,258,443...85,272,144
JBrowse link
G Mcm6 minichromosome maintenance complex component 6 increases expression
multiple interactions
ISO Atropine results in increased expression of MCM6 mRNA
[Parathion co-treated with Atropine] results in increased expression of MCM6 mRNA
CTD PMID:17390078 NCBI chr13:39,826,745...39,851,937
Ensembl chr13:39,826,763...39,851,960
JBrowse link
G Nefh neurofilament heavy chain affects expression EXP Atropine affects the expression of NEFH mRNA CTD PMID:22954530 NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 increases expression ISO Atropine results in increased expression of NLRP3 mRNA CTD PMID:28138970 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP Atropine inhibits the reaction [Indomethacin results in increased activity of NOS2 protein]; Atropine inhibits the reaction [Indomethacin results in increased expression of NOS2 mRNA] CTD PMID:15610444 PMID:16944022 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Notch4 notch receptor 4 multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of NOTCH4 protein] CTD PMID:17390078 NCBI chr20:4,160,362...4,184,466
Ensembl chr20:4,160,445...4,184,465
JBrowse link
G Nppa natriuretic peptide A affects activity EXP Atropine affects the activity of NPPA protein modified form CTD PMID:1363893 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
JBrowse link
G Oprl1 opioid related nociceptin receptor 1 multiple interactions EXP Atropine inhibits the reaction [PNOC protein binds to and results in increased activity of OPRL1 protein] CTD PMID:12007927 NCBI chr 3:168,831,934...168,839,920
Ensembl chr 3:168,834,003...168,839,920
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO Atropine inhibits the reaction [Malathion results in increased expression of PCNA]; Atropine inhibits the reaction [Parathion results in increased expression of PCNA] CTD PMID:12762645 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Pnoc prepronociceptin multiple interactions EXP Atropine inhibits the reaction [PNOC protein binds to and results in increased activity of OPRL1 protein] CTD PMID:12007927 NCBI chr15:39,624,635...39,652,463
Ensembl chr15:39,624,641...39,651,867
JBrowse link
G Pomc proopiomelanocortin multiple interactions EXP Atropine inhibits the reaction [Acetylcholine results in increased expression of POMC protein] CTD PMID:7588217 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO [Atropine co-treated with Glucose] binds to PPARA protein; Atropine inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]] CTD PMID:18812576 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP Atropine affects the reaction [Indomethacin results in increased expression of PTGS2]; Atropine inhibits the reaction [Indomethacin results in increased expression of PTGS2 mRNA]; Atropine inhibits the reaction [Indomethacin results in increased expression of PTGS2]; Atropine inhibits the reaction [SC 560 results in increased expression of PTGS2 mRNA] CTD PMID:15104355 PMID:15610444 PMID:16259740 PMID:16804302 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Ptk2 protein tyrosine kinase 2 multiple interactions ISO Atropine inhibits the reaction [oxotremorine M inhibits the reaction [[wortmannin co-treated with lysophosphatidic acid] results in increased phosphorylation of PTK2 protein]]; Atropine inhibits the reaction [oxotremorine M inhibits the reaction [[wortmannin co-treated with oxophenylarsine] results in increased phosphorylation of PTK2 protein]]; Atropine inhibits the reaction [oxotremorine M promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with wortmannin] results in increased phosphorylation of PTK2 protein]] CTD PMID:10537051 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783
JBrowse link
G Pxn paxillin multiple interactions ISO Atropine inhibits the reaction [[oxotremorine M co-treated with wortmannin] inhibits the reaction [oxophenylarsine results in increased phosphorylation of PXN protein]] CTD PMID:10537051 NCBI chr12:41,060,791...41,107,962
Ensembl chr12:41,060,791...41,107,931
JBrowse link
G Rac3 Rac family small GTPase 3 multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of RAC3 protein] CTD PMID:17390078 NCBI chr10:106,002,808...106,005,244 JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman affects the phosphorylation of RELA protein] CTD PMID:21971501 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Rhoa ras homolog family member A multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of RHOA protein] CTD PMID:17390078 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
JBrowse link
G Slc22a1 solute carrier family 22 member 1 multiple interactions ISO Atropine inhibits the reaction [SLC22A1 protein results in increased transport of 1-Methyl-4-phenylpyridinium]; Atropine inhibits the reaction [SLC22A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:16263091 PMID:21641380 NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Atropine inhibits the reaction [SLC22A2 protein results in increased transport of 1-Methyl-4-phenylpyridinium]; Atropine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium]; Atropine inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] CTD PMID:16263091 PMID:21599003 PMID:23770354 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
JBrowse link
G Slc22a3 solute carrier family 22 member 3 increases uptake
multiple interactions
ISO SLC22A3 protein results in increased uptake of Atropine
Atropine inhibits the reaction [SLC22A3 protein results in increased transport of 1-Methyl-4-phenylpyridinium]
CTD PMID:16263091 NCBI chr 1:48,235,476...48,324,617
Ensembl chr 1:48,235,476...48,324,612
JBrowse link
G Slc22a4 solute carrier family 22 member 4 multiple interactions ISO Atropine inhibits the reaction [SLC22A4 protein results in increased uptake of Tetraethylammonium] CTD PMID:21641380 NCBI chr10:38,133,333...38,179,932 JBrowse link
G Slc47a1 solute carrier family 47 member 1 multiple interactions ISO Atropine inhibits the reaction [SLC47A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:46,034,115...46,088,617
Ensembl chr10:46,034,122...46,087,637
JBrowse link
G Slc47a2 solute carrier family 47 member 2 multiple interactions ISO Atropine inhibits the reaction [SLC47A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:45,990,806...46,033,937
Ensembl chr10:45,991,095...46,033,904
JBrowse link
G Slpi secretory leukocyte peptidase inhibitor increases expression ISO Atropine results in increased expression of SLPI mRNA CTD PMID:32816093 NCBI chr 3:153,082,208...153,084,457
Ensembl chr 3:153,082,369...153,084,453
JBrowse link
G Socs3 suppressor of cytokine signaling 3 multiple interactions ISO [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of SOCS3 mRNA] CTD PMID:22245128 NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787
JBrowse link
G Spn sialophorin increases response to substance ISO SPN protein results in increased susceptibility to Atropine CTD PMID:18711009 NCBI chr 1:181,746,937...181,759,564
Ensembl chr 1:181,746,429...181,759,628
JBrowse link
G Tat tyrosine aminotransferase multiple interactions EXP [Atropine co-treated with Obidoxime Chloride co-treated with Diazepam] inhibits the reaction [Dichlorvos results in increased expression of TAT protein] CTD PMID:7761789 NCBI chr19:37,947,153...37,957,717
Ensembl chr19:37,947,112...37,958,031
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP Atropine inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 mRNA] CTD PMID:18472332 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of TNF mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of TNF protein] CTD PMID:22245128 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO Atropine inhibits the reaction [Malathion results in increased expression of TP53 protein]; Atropine inhibits the reaction [Parathion results in increased expression of TP53 protein] CTD PMID:12762645 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Trio trio Rho guanine nucleotide exchange factor multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of TRIO protein] CTD PMID:17390078 NCBI chr 2:78,505,069...78,801,384
Ensembl chr 2:78,505,070...78,803,135
JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 decreases response to substance ISO TRPA1 gene mutant form results in decreased susceptibility to Atropine CTD PMID:29627347 NCBI chr 5:4,379,999...4,433,243
Ensembl chr 5:4,379,999...4,433,570
JBrowse link
G Tshb thyroid stimulating hormone subunit beta multiple interactions EXP [pralidoxime co-treated with Atropine] inhibits the reaction [methamidophos results in decreased expression of TSHB protein] CTD PMID:15891268 NCBI chr 2:190,224,676...190,229,559
Ensembl chr 2:190,224,676...190,229,559
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of VCAM1 mRNA] CTD PMID:22245128 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
butylscopolamine bromide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Butylscopolammonium Bromide inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
JBrowse link
cocaine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aacs acetoacetyl-CoA synthetase affects expression EXP Cocaine affects the expression of AACS mRNA CTD PMID:20187946 NCBI chr12:31,113,098...31,156,411
Ensembl chr12:31,113,098...31,160,954
JBrowse link
G Aadac arylacetamide deacetylase decreases expression EXP Cocaine results in decreased expression of AADAC mRNA CTD PMID:17898221 NCBI chr 2:144,163,436...144,186,086
Ensembl chr 2:144,135,319...144,174,734
JBrowse link
G Aanat aralkylamine N-acetyltransferase affects response to substance ISO AANAT protein affects the susceptibility to Cocaine CTD PMID:12138020 NCBI chr10:101,827,072...101,831,805
Ensembl chr10:101,827,301...101,831,801
JBrowse link
G Abat 4-aminobutyrate aminotransferase increases response to substance ISO ABAT mRNA results in increased susceptibility to Cocaine CTD PMID:10850552 NCBI chr10:6,996,688...7,092,835
Ensembl chr10:6,999,819...7,092,835
JBrowse link
G Abca4 ATP binding cassette subfamily A member 4 decreases expression EXP Cocaine results in decreased expression of ABCA4 mRNA CTD PMID:27899881 NCBI chr 2:210,164,813...210,302,069
Ensembl chr 2:210,164,813...210,302,069
JBrowse link
G Abca5 ATP binding cassette subfamily A member 5 multiple interactions ISO HDAC5 affects the reaction [Cocaine affects the expression of ABCA5 mRNA] CTD PMID:17988634 NCBI chr10:95,240,159...95,309,195
Ensembl chr10:95,240,154...95,308,976
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 affects expression EXP Cocaine affects the expression of ABCC3 mRNA CTD PMID:20187946 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 affects expression EXP Cocaine affects the expression of ABCC5 mRNA CTD PMID:20187946 NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253
JBrowse link
G Abcc9 ATP binding cassette subfamily C member 9 affects expression EXP Cocaine affects the expression of ABCC9 mRNA CTD PMID:20187946 NCBI chr 4:175,531,854...175,655,849
Ensembl chr 4:175,532,547...175,655,356
JBrowse link
G Abcd4 ATP binding cassette subfamily D member 4 affects expression EXP Cocaine affects the expression of ABCD4 mRNA CTD PMID:20187946 NCBI chr 6:104,246,459...104,260,965
Ensembl chr 6:104,246,468...104,280,276
JBrowse link
G Abhd1 abhydrolase domain containing 1 decreases expression ISO Cocaine results in decreased expression of ABHD1 mRNA CTD PMID:18355967 NCBI chr 6:25,422,526...25,427,514
Ensembl chr 6:25,422,526...25,427,514
JBrowse link
G Abhd14a abhydrolase domain containing 14A affects expression EXP Cocaine affects the expression of ABHD14A mRNA CTD PMID:20187946 NCBI chr 8:107,079,139...107,089,004
Ensembl chr 8:107,079,144...107,086,985
JBrowse link
G Abhd17a abhydrolase domain containing 17A, depalmitoylase affects expression EXP Cocaine affects the expression of ABHD17A mRNA CTD PMID:20187946 NCBI chr 7:9,124,332...9,132,762
Ensembl chr 7:9,124,332...9,130,762
JBrowse link
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase affects expression ISO Cocaine affects the expression of ABL1 mRNA CTD PMID:15681117 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065
JBrowse link
G Acaa1b acetyl-Coenzyme A acyltransferase 1B increases expression ISO Cocaine results in increased expression of ACAA1 mRNA CTD PMID:18355967 NCBI chr 8:118,872,996...118,881,852
Ensembl chr 8:118,872,997...118,881,825
JBrowse link
G Acan aggrecan affects expression EXP Cocaine affects the expression of ACAN mRNA CTD PMID:20187946 NCBI chr 1:132,981,034...133,044,416
Ensembl chr 1:132,981,582...133,043,627
JBrowse link
G Ace angiotensin I converting enzyme multiple interactions ISO ACE inhibits the reaction [Cocaine affects the abundance of Dinoprostone]; ACE inhibits the reaction [Cocaine affects the abundance of Epoprostenol] CTD PMID:14738173 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
JBrowse link
G Acin1 apoptotic chromatin condensation inducer 1 affects expression ISO Cocaine affects the expression of ACIN1 mRNA CTD PMID:15681117 NCBI chr15:28,102,112...28,147,001
Ensembl chr15:28,102,112...28,147,001
JBrowse link
G Ackr2 atypical chemokine receptor 2 affects expression EXP Cocaine affects the expression of ACKR2 mRNA CTD PMID:20187946 NCBI chr 8:121,559,563...121,573,633
Ensembl chr 8:121,561,211...121,573,582
JBrowse link
G Aco2 aconitase 2 increases expression ISO Cocaine results in increased expression of ACO2 protein modified form CTD PMID:24096156 NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261
JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 affects expression EXP Cocaine affects the expression of ACSL5 mRNA CTD PMID:20187946 NCBI chr 1:254,289,513...254,336,608
Ensembl chr 1:254,292,521...254,336,607
JBrowse link
G Acss1 acyl-CoA synthetase short-chain family member 1 decreases expression EXP Cocaine results in decreased expression of ACSS1 mRNA CTD PMID:27899881 NCBI chr 3:139,450,383...139,500,325
Ensembl chr 3:139,450,383...139,500,325
JBrowse link
G Actg2 actin gamma 2, smooth muscle decreases expression ISO Cocaine results in decreased expression of ACTG2 mRNA CTD PMID:20948987 NCBI chr 4:116,021,832...116,046,475
Ensembl chr 4:116,021,832...116,046,465
JBrowse link
G Actn2 actinin alpha 2 increases expression ISO Cocaine results in increased expression of ACTN2 mRNA CTD PMID:15009677 PMID:16710320 NCBI chr17:58,143,334...58,210,622
Ensembl chr17:58,142,625...58,210,622
JBrowse link
G Acvr1c activin A receptor type 1C increases expression EXP Cocaine results in increased expression of ACVR1C mRNA CTD PMID:17898221 NCBI chr 3:42,815,490...42,892,423
Ensembl chr 3:42,822,610...42,892,327
JBrowse link
G Acy3 aminoacylase 3 affects expression EXP Cocaine affects the expression of ACY3 mRNA CTD PMID:20187946 NCBI chr 1:201,279,751...201,285,803
Ensembl chr 1:201,279,851...201,283,175
JBrowse link
G Adam19 ADAM metallopeptidase domain 19 decreases expression EXP Cocaine results in decreased expression of ADAM19 mRNA CTD PMID:17898221 NCBI chr10:30,491,362...30,583,115
Ensembl chr10:30,491,405...30,583,105
JBrowse link
G Adam1a ADAM metallopeptidase domain 1a multiple interactions ISO HDAC5 affects the reaction [Cocaine affects the expression of ADAM1A mRNA] CTD PMID:17988634 NCBI chr12:35,017,433...35,020,300
Ensembl chr12:35,017,315...35,020,311
JBrowse link
G Adamts19 ADAM metallopeptidase with thrombospondin type 1 motif, 19 decreases expression EXP Cocaine results in decreased expression of ADAMTS19 mRNA CTD PMID:27899881 NCBI chr18:52,346,448...52,531,245
Ensembl chr18:52,347,428...52,530,509
JBrowse link
G Adat2 adenosine deaminase, tRNA-specific 2 decreases expression EXP Cocaine results in decreased expression of ADAT2 mRNA CTD PMID:17898221 NCBI chr 1:7,954,520...7,975,254
Ensembl chr 1:7,954,631...7,975,251
JBrowse link
G Adcy2 adenylate cyclase 2 affects expression EXP Cocaine affects the expression of ADCY2 mRNA CTD PMID:20187946 NCBI chr 1:34,375,639...34,822,237
Ensembl chr 1:34,375,895...34,822,236
JBrowse link
G Adcy8 adenylate cyclase 8 affects expression EXP Cocaine affects the expression of ADCY8 mRNA CTD PMID:20187946 NCBI chr 7:96,417,310...96,665,911
Ensembl chr 7:96,417,324...96,665,911
JBrowse link
G Adcyap1 adenylate cyclase activating polypeptide 1 increases expression
multiple interactions
ISO Cocaine results in increased expression of ADCYAP1 mRNA
ADCYAP1 protein modified form affects the reaction [Cocaine results in increased cleavage of CASP3 protein]; ADCYAP1 protein modified form affects the reaction [Cocaine results in increased expression of BAX protein]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide affects the reaction [IL6 protein affects the reaction [Cocaine results in increased expression of ADCYAP1 mRNA]]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Cocaine results in increased expression of ADCYAP1 mRNA]; IL6 protein affects the reaction [Cocaine results in increased expression of ADCYAP1 mRNA]; TNF protein affects the reaction [Cocaine results in increased expression of ADCYAP1 mRNA]
CTD PMID:29673861 NCBI chr 9:113,102,632...113,122,500
Ensembl chr 9:113,103,718...113,109,773
JBrowse link
G Adcyap1r1 ADCYAP receptor type I increases expression
multiple interactions
ISO Cocaine results in increased expression of ADCYAP1R1 mRNA
alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide affects the reaction [IL6 protein affects the reaction [Cocaine results in increased expression of ADCYAP1R1 mRNA]]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Cocaine results in increased expression of ADCYAP1R1 mRNA]; IL6 protein affects the reaction [Cocaine results in increased expression of ADCYAP1R1 mRNA]; TNF protein affects the reaction [Cocaine results in increased expression of ADCYAP1R1 mRNA]
CTD PMID:29673861 NCBI chr 4:84,593,558...84,642,700
Ensembl chr 4:84,593,892...84,642,700
JBrowse link
G Adgra1 adhesion G protein-coupled receptor A1 multiple interactions ISO [Cocaine co-treated with FOS protein mutant form] results in increased expression of ADGRA1 mRNA CTD PMID:18355967 NCBI chr 1:194,629,744...194,673,254
Ensembl chr 1:194,629,726...194,672,550
JBrowse link
G Adgre1 adhesion G protein-coupled receptor E1 affects expression EXP Cocaine affects the expression of ADGRE1 mRNA CTD PMID:20187946 NCBI chr 9:2,242,476...2,398,000
Ensembl chr 9:2,242,474...2,398,000
JBrowse link
G Adgrf1 adhesion G protein-coupled receptor F1 decreases expression EXP Cocaine results in decreased expression of ADGRF1 mRNA CTD PMID:17898221 NCBI chr 9:17,661,258...17,696,359 JBrowse link
G Adgrl1 adhesion G protein-coupled receptor L1 affects expression EXP Cocaine affects the expression of ADGRL1 mRNA CTD PMID:20187946 NCBI chr19:24,202,405...24,244,137
Ensembl chr19:24,204,360...24,244,139
JBrowse link
G Adgrl3 adhesion G protein-coupled receptor L3 affects expression EXP Cocaine affects the expression of ADGRL3 mRNA CTD PMID:20187946 NCBI chr14:26,336,320...27,104,060
Ensembl chr14:26,368,277...27,105,860
JBrowse link
G Adora1 adenosine A1 receptor affects expression
affects response to substance
EXP
ISO
Cocaine affects the expression of ADORA1 mRNA; Cocaine affects the expression of ADORA1 protein
ADORA1 affects the susceptibility to Cocaine
CTD PMID:12358776 PMID:19092996 NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801
JBrowse link
G Adora2a adenosine A2a receptor increases response to substance
increases expression
ISO ADORA2A results in increased susceptibility to Cocaine
Cocaine deficiency results in increased expression of ADORA2A mRNA
CTD PMID:16123743 PMID:27126842 NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386
JBrowse link
G Adora2b adenosine A2B receptor affects expression EXP Cocaine affects the expression of ADORA2B mRNA CTD PMID:20187946 NCBI chr10:46,940,394...46,956,772
Ensembl chr10:46,940,384...46,956,772
JBrowse link
G Adra1b adrenoceptor alpha 1B increases response to substance ISO ADRA1B gene results in increased susceptibility to Cocaine CTD PMID:14556232 NCBI chr10:28,255,025...28,373,418
Ensembl chr10:28,255,025...28,312,919
JBrowse link
G Adrb1 adrenoceptor beta 1 multiple interactions
affects expression
EXP Betaxolol affects the reaction [Cocaine affects the expression of ADRB1 protein]; Betaxolol inhibits the reaction [Cocaine affects the expression of ADRB1 protein] CTD PMID:17513029 PMID:18596687 NCBI chr 1:255,772,217...255,773,617
Ensembl chr 1:255,771,597...255,807,259
JBrowse link
G Aff4 AF4/FMR2 family, member 4 increases expression EXP Cocaine results in increased expression of AFF4 mRNA CTD PMID:17898221 NCBI chr10:37,498,825...37,579,751
Ensembl chr10:37,498,825...37,579,751
JBrowse link
G Afmid arylformamidase increases expression EXP Cocaine results in increased expression of AFMID mRNA CTD PMID:17898221 NCBI chr10:103,046,129...103,061,718
Ensembl chr10:103,046,180...103,061,718
JBrowse link
G Afp alpha-fetoprotein increases expression EXP Cocaine results in increased expression of AFP mRNA CTD PMID:27899881 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
JBrowse link
G Agap2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 affects expression EXP Cocaine affects the expression of AGAP2 mRNA CTD PMID:20187946 NCBI chr 7:62,897,282...62,914,295
Ensembl chr 7:62,897,282...62,914,295
JBrowse link
G Ago2 argonaute RISC catalytic component 2 multiple interactions
affects response to substance
ISO AGO2 protein affects the reaction [Cocaine results in increased expression of MIR130A mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR136 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR137 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR138-1 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR148B mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR154 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR181A1 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR186 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR301B mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR324 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR337 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR369 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR376A mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR376C mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR380 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR384 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR467B mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR488 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR500 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR544 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR665 mRNA]
AGO2 protein affects the susceptibility to Cocaine
CTD PMID:20643829 NCBI chr 7:105,018,202...105,105,120
Ensembl chr 7:105,029,120...105,104,974
JBrowse link
G Aif1l allograft inflammatory factor 1-like decreases expression ISO Cocaine results in decreased expression of AIF1L mRNA CTD PMID:15009677 NCBI chr 3:15,229,476...15,254,033
Ensembl chr 3:15,229,524...15,254,023
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 affects expression
increases expression
ISO Cocaine affects the expression of AIFM1 mRNA
Cocaine results in increased expression of AIFM1 mRNA
CTD PMID:15681117 PMID:18000554 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256
JBrowse link
G Aifm2 apoptosis inducing factor, mitochondria associated 2 affects expression ISO Cocaine affects the expression of AIFM2 mRNA CTD PMID:15681117 NCBI chr20:29,654,283...29,679,239
Ensembl chr20:29,652,927...29,679,236
JBrowse link
G Ak1 adenylate kinase 1 decreases expression ISO Cocaine results in decreased expression of AK1 mRNA CTD PMID:15009677 NCBI chr 3:15,912,431...15,923,045 JBrowse link
G Ak3 adenylate kinase 3 affects expression EXP Cocaine affects the expression of AK3 mRNA CTD PMID:20187946 NCBI chr 1:226,737,472...226,764,647
Ensembl chr 1:226,739,318...226,764,625
JBrowse link
G Akr1d1 aldo-keto reductase family 1, member D1 affects expression EXP Cocaine affects the expression of AKR1D1 mRNA CTD PMID:20187946 NCBI chr 4:66,154,246...66,187,505
Ensembl chr 4:66,154,248...66,186,372
JBrowse link
G Akr1e2 aldo-keto reductase family 1, member E2 affects expression EXP Cocaine affects the expression of AKR1E1 mRNA CTD PMID:20187946 NCBI chr17:65,735,909...65,750,441
Ensembl chr17:65,735,943...65,750,441
JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 affects expression EXP Cocaine affects the expression of AKR7A3 mRNA CTD PMID:20187946 NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394
JBrowse link
G Akt1 AKT serine/threonine kinase 1 affects expression
multiple interactions
increases phosphorylation
EXP
ISO
Cocaine affects the expression of AKT1 mRNA
[Cocaine co-treated with cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester] results in increased phosphorylation of AKT1 protein
Cocaine results in increased phosphorylation of AKT1 protein
Cocaine affects the reaction [ILK protein affects the phosphorylation of AKT1 protein]
CTD PMID:18702665 PMID:20187946 PMID:25933444 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Alcam activated leukocyte cell adhesion molecule increases expression EXP Cocaine results in increased expression of ALCAM mRNA CTD PMID:17898221 NCBI chr11:48,336,123...48,536,296
Ensembl chr11:48,336,169...48,537,954
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member multiple interactions EXP [[CVT-10216 results in decreased activity of ALDH2 protein] which results in increased abundance of Tetrahydropapaveroline] inhibits the reaction [Cocaine results in increased abundance of and results in increased secretion of Dopamine]; [ALDH2 protein affects the abundance of Tetrahydropapaveroline] which affects the susceptibility to Cocaine; ALDH2 protein affects the reaction [Cocaine results in increased abundance of Dopamine] CTD PMID:20729865 NCBI chr12:34,949,549...34,982,527 JBrowse link
G Ambra1 autophagy and beclin 1 regulator 1 decreases expression EXP Cocaine results in decreased expression of AMBRA1 mRNA CTD PMID:17898221 NCBI chr 3:77,700,936...77,890,221
Ensembl chr 3:77,700,936...77,890,221
JBrowse link
G Amh anti-Mullerian hormone increases expression EXP Cocaine results in increased expression of AMH mRNA CTD PMID:17898221 NCBI chr 7:8,906,776...8,909,184
Ensembl chr 7:8,906,836...8,909,282
JBrowse link
G Amigo1 adhesion molecule with Ig like domain 1 affects expression EXP Cocaine affects the expression of AMIGO1 mRNA CTD PMID:20187946 NCBI chr 2:195,823,138...195,828,593
Ensembl chr 2:195,823,042...195,829,585
JBrowse link
G Amigo3 adhesion molecule with Ig like domain 3 affects expression EXP Cocaine affects the expression of AMIGO3 mRNA CTD PMID:20187946 NCBI chr 8:108,741,899...108,743,425
Ensembl chr 8:108,693,060...108,744,555
JBrowse link
G Amn1 antagonist of mitotic exit network 1 homolog decreases expression EXP Cocaine results in decreased expression of AMN1 mRNA CTD PMID:17898221 NCBI chr 4:182,155,140...182,182,085
Ensembl chr 4:182,155,142...182,182,016
JBrowse link
G Ankrd54 ankyrin repeat domain 54 affects expression EXP Cocaine affects the expression of ANKRD54 mRNA CTD PMID:20187946 NCBI chr 7:110,614,942...110,627,739
Ensembl chr 7:110,614,951...110,627,675
JBrowse link
G Anks1b ankyrin repeat and sterile alpha motif domain containing 1B decreases expression EXP Cocaine results in decreased expression of ANKS1B mRNA CTD PMID:17898221 NCBI chr 7:24,313,810...25,479,307
Ensembl chr 7:24,312,843...25,477,693
JBrowse link
G Anxa7 annexin A7 affects expression EXP Cocaine affects the expression of ANXA7 mRNA CTD PMID:20187946 NCBI chr15:3,821,798...3,849,659
Ensembl chr15:3,821,845...3,849,385
JBrowse link
G Ap1ar adaptor-related protein complex 1 associated regulatory protein increases expression EXP Cocaine results in increased expression of AP1AR mRNA CTD PMID:17898221 NCBI chr 2:216,276,631...216,309,020
Ensembl chr 2:216,276,631...216,309,013
JBrowse link
G Ap2b1 adaptor related protein complex 2 subunit beta 1 affects expression EXP Cocaine affects the expression of AP2B1 mRNA CTD PMID:20187946 NCBI chr10:68,099,397...68,205,023
Ensembl chr10:68,099,547...68,205,013
JBrowse link
G Ap2m1 adaptor related protein complex 2 subunit mu 1 increases expression EXP Cocaine results in increased expression of AP2M1 protein CTD PMID:25100957 NCBI chr11:80,355,307...80,364,218
Ensembl chr11:80,328,041...80,364,140
JBrowse link
G Ap2s1 adaptor related protein complex 2 subunit sigma 1 decreases expression ISO Cocaine results in decreased expression of AP2S1 mRNA CTD PMID:15009677 NCBI chr 1:77,417,496...77,428,903
Ensembl chr 1:77,417,477...77,428,905
JBrowse link
G Ap5m1 adaptor related protein complex 5 subunit mu 1 affects expression EXP Cocaine affects the expression of AP5M1 mRNA CTD PMID:20187946 NCBI chr15:22,355,478...22,385,222
Ensembl chr15:22,355,500...22,377,750
JBrowse link
G Apcs amyloid P component, serum increases expression ISO Cocaine results in increased expression of APCS protein CTD PMID:12714198 NCBI chr13:85,373,338...85,374,134
Ensembl chr13:85,373,220...85,374,298
JBrowse link
G Aph1a aph-1 homolog A, gamma secretase subunit affects expression EXP Cocaine affects the expression of APH1A mRNA CTD PMID:20187946 NCBI chr 2:183,437,676...183,443,113
Ensembl chr 2:183,438,434...183,441,955
JBrowse link
G Aplnr apelin receptor increases expression EXP Cocaine results in increased expression of APLNR mRNA CTD PMID:17898221 NCBI chr 3:70,217,407...70,221,052
Ensembl chr 3:70,217,385...70,221,050
JBrowse link
G Apol11a apolipoprotein L 11a decreases expression EXP Cocaine results in decreased expression of APOL11A mRNA CTD PMID:27899881 NCBI chr 7:109,248,260...109,262,266
Ensembl chr 7:109,248,942...109,253,716
JBrowse link
G Apol2 apolipoprotein L, 2 increases expression ISO Cocaine results in increased expression of APOL2 mRNA CTD PMID:17205118 NCBI chr 7:109,331,367...109,338,632 JBrowse link
G Apold1 apolipoprotein L domain containing 1 affects expression EXP Cocaine affects the expression of APOLD1 mRNA CTD PMID:20187946 NCBI chr 4:167,768,437...167,825,706
Ensembl chr 4:167,818,271...167,825,706
JBrowse link
G Apoo apolipoprotein O increases expression EXP Cocaine results in increased expression of APOO protein CTD PMID:25100957 NCBI chr  X:59,157,971...59,262,940
Ensembl chr  X:59,158,049...59,262,940
JBrowse link
G App amyloid beta precursor protein decreases expression
increases expression
EXP
ISO
Cocaine results in decreased expression of APP mRNA
Cocaine results in increased expression of APP mRNA
CTD PMID:15009677 PMID:16710320 PMID:17898221 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 increases expression EXP Cocaine results in increased expression of APPL1 mRNA CTD PMID:17898221 NCBI chr16:2,118,503...2,166,741
Ensembl chr16:2,121,255...2,166,692
JBrowse link
G Arc activity-regulated cytoskeleton-associated protein affects expression
increases expression
multiple interactions
EXP Cocaine affects the expression of ARC mRNA
Cocaine results in increased expression of ARC mRNA; Cocaine results in increased expression of ARC protein
Reserpine inhibits the reaction [Cocaine results in increased expression of ARC mRNA]
CTD PMID:7722525 PMID:12117546 PMID:15254092 PMID:17851536 PMID:18311559 More... NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378
JBrowse link
G Arf4 ADP-ribosylation factor 4 decreases expression EXP Cocaine results in decreased expression of ARF4 protein CTD PMID:25100957 NCBI chr16:1,896,692...1,913,267
Ensembl chr16:1,896,546...1,913,261
JBrowse link
G Arhgap1 Rho GTPase activating protein 1 increases expression EXP Cocaine results in increased expression of ARHGAP1 protein CTD PMID:25100957 NCBI chr 3:77,621,377...77,643,400
Ensembl chr 3:77,620,655...77,643,396
JBrowse link
G Arhgap29 Rho GTPase activating protein 29 decreases expression ISO Cocaine results in decreased expression of ARHGAP29 mRNA CTD PMID:12629581 NCBI chr 2:210,060,036...210,132,572
Ensembl chr 2:210,071,199...210,132,028
JBrowse link
G Arhgap30 Rho GTPase activating protein 30 increases expression EXP Cocaine results in increased expression of ARHGAP30 mRNA CTD PMID:17898221 NCBI chr13:83,822,290...83,843,634
Ensembl chr13:83,822,283...83,854,885
JBrowse link
G Arhgap44 Rho GTPase activating protein 44 decreases expression EXP Cocaine results in decreased expression of ARHGAP44 protein CTD PMID:25100957 NCBI chr10:49,655,583...49,822,876
Ensembl chr10:49,655,584...49,824,297
JBrowse link
G Arhgap5 Rho GTPase activating protein 5 increases expression EXP Cocaine results in increased expression of ARHGAP5 mRNA CTD PMID:17898221 NCBI chr 6:69,975,904...70,039,299
Ensembl chr 6:69,976,214...70,037,660
JBrowse link
G Arhgap9 Rho GTPase activating protein 9 decreases expression EXP Cocaine results in decreased expression of ARHGAP9 mRNA CTD PMID:17898221 NCBI chr 7:63,148,573...63,157,025
Ensembl chr 7:63,148,900...63,157,524
JBrowse link
G Arhgef1 Rho guanine nucleotide exchange factor 1 affects expression EXP Cocaine affects the expression of ARHGEF1 mRNA CTD PMID:20187946 NCBI chr 1:80,499,026...80,520,954
Ensembl chr 1:80,499,131...80,520,953
JBrowse link
G Arhgef7 Rho guanine nucleotide exchange factor 7 affects expression EXP Cocaine affects the expression of ARHGEF7 mRNA CTD PMID:20187946 NCBI chr16:77,671,021...77,782,593
Ensembl chr16:77,671,023...77,782,697
JBrowse link
G Armcx6 armadillo repeat containing, X-linked 6 affects expression EXP Cocaine affects the expression of ARMCX6 mRNA CTD PMID:20187946 NCBI chr  X:97,929,032...97,932,032
Ensembl chr  X:97,929,041...97,931,977
JBrowse link
G Arntl aryl hydrocarbon receptor nuclear translocator-like decreases expression ISO Cocaine results in decreased expression of ARNTL mRNA CTD PMID:15994025 NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231
JBrowse link
G Arpc1a actin related protein 2/3 complex, subunit 1A increases expression EXP Cocaine results in increased expression of ARPC1A protein CTD PMID:25100957 NCBI chr12:9,502,496...9,525,304
Ensembl chr12:9,502,501...9,525,330
JBrowse link
G Arpp19 cAMP-regulated phosphoprotein 19 multiple interactions EXP Cocaine inhibits the reaction [SK&F 81297 results in increased phosphorylation of ARPP19 protein] CTD PMID:11268215 NCBI chr 8:75,779,640...75,802,474
Ensembl chr 8:75,779,523...75,802,452
JBrowse link
G Arpp21 cAMP regulated phosphoprotein 21 multiple interactions
increases expression
EXP
ISO
Cocaine inhibits the reaction [SK&F 81297 results in increased phosphorylation of ARPP21 protein]
Cocaine deficiency results in increased expression of ARPP21 mRNA
CTD PMID:11268215 PMID:27126842 NCBI chr 8:112,034,636...112,199,273
Ensembl chr 8:112,034,642...112,194,297
JBrowse link
G Art5 ADP-ribosyltransferase 5 increases expression EXP Cocaine results in increased expression of ART5 mRNA CTD PMID:17898221 NCBI chr 1:156,473,362...156,483,324
Ensembl chr 1:156,473,362...156,483,324
JBrowse link
G As3mt arsenite methyltransferase affects expression EXP Cocaine affects the expression of AS3MT mRNA CTD PMID:20187946 NCBI chr 1:245,595,939...245,628,921
Ensembl chr 1:245,596,108...245,627,872
JBrowse link
G Asap1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 decreases expression EXP Cocaine results in decreased expression of ASAP1 mRNA CTD PMID:17898221 NCBI chr 7:95,786,130...96,093,111
Ensembl chr 7:95,787,818...96,092,754
JBrowse link
G Atad1 ATPase family, AAA domain containing 1 increases expression EXP Cocaine results in increased expression of ATAD1 mRNA CTD PMID:17898221 NCBI chr 1:230,544,227...230,610,524
Ensembl chr 1:230,544,047...230,596,548
JBrowse link
G Atad5 ATPase family, AAA domain containing 5 decreases expression EXP Cocaine results in decreased expression of ATAD5 mRNA CTD PMID:17898221 NCBI chr10:65,070,682...65,118,489
Ensembl chr10:65,070,689...65,117,845
JBrowse link
G Ate1 arginyltransferase 1 increases expression EXP Cocaine results in increased expression of ATE1 mRNA CTD PMID:17898221 NCBI chr 1:184,961,548...185,081,112
Ensembl chr 1:184,963,562...185,080,908
JBrowse link
G Atf3 activating transcription factor 3 increases expression
decreases expression
EXP Cocaine results in increased expression of ATF3 mRNA
Cocaine results in decreased expression of ATF3 mRNA
CTD PMID:23644055 PMID:27899881 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Atf4 activating transcription factor 4 increases expression EXP Cocaine results in increased expression of ATF4; Cocaine results in increased expression of ATF4 mRNA CTD PMID:18593214 PMID:23644055 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Atf6 activating transcription factor 6 affects expression EXP Cocaine affects the expression of ATF6 mRNA CTD PMID:23644055 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
JBrowse link
G Atf7 activating transcription factor 7 affects expression ISO Cocaine affects the expression of ATF7 mRNA CTD PMID:15681117 NCBI chr 7:133,660,491...133,750,902
Ensembl chr 7:133,663,294...133,750,848
JBrowse link
G Atg2b autophagy related 2B affects expression EXP Cocaine affects the expression of ATG2B mRNA CTD PMID:20187946 NCBI chr 6:124,522,283...124,592,412
Ensembl chr 6:124,525,523...124,592,015
JBrowse link
G Atg4b autophagy related 4B, cysteine peptidase affects expression EXP Cocaine affects the expression of ATG4B mRNA CTD PMID:20187946 NCBI chr 9:94,282,417...94,314,109
Ensembl chr 9:94,282,509...94,314,103
JBrowse link
G Atm ATM serine/threonine kinase multiple interactions
increases expression
ISO EHMT2 inhibits the reaction [Cocaine results in increased expression of ATM mRNA] CTD PMID:20056891 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Atp10a ATPase phospholipid transporting 10A (putative) decreases expression EXP Cocaine results in decreased expression of ATP10A mRNA CTD PMID:17898221 PMID:27899881 NCBI chr 1:109,556,760...109,730,440
Ensembl chr 1:109,556,782...109,730,437
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 affects expression ISO Cocaine affects the expression of ATP1A1 mRNA CTD PMID:18355967 NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837
JBrowse link
G Atp1a3 ATPase Na+/K+ transporting subunit alpha 3 increases expression
affects expression
EXP Cocaine results in increased expression of ATP1A3 mRNA
Cocaine affects the expression of ATP1A3 mRNA
CTD PMID:16076954 PMID:20187946 NCBI chr 1:80,572,790...80,601,936
Ensembl chr 1:80,572,796...80,601,918
JBrowse link
G Atp1b2 ATPase Na+/K+ transporting subunit beta 2 increases expression EXP Cocaine results in increased expression of ATP1B2 mRNA CTD PMID:16076954 NCBI chr10:54,318,698...54,324,933
Ensembl chr10:54,318,701...54,324,933
JBrowse link
G Atp1b3 ATPase Na+/K+ transporting subunit beta 3 increases expression
multiple interactions
ISO Cocaine results in increased expression of ATP1B3 mRNA
FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of ATP1B3 mRNA]
CTD PMID:18355967 NCBI chr 8:96,910,265...96,941,592
Ensembl chr 8:96,910,309...96,941,598
JBrowse link
G Atp5f1a ATP synthase F1 subunit alpha affects expression ISO Cocaine affects the expression of ATP5F1A protein CTD PMID:19393250 NCBI chr18:71,292,406...71,300,342
Ensembl chr18:71,292,374...71,300,794
JBrowse link
G Atp5f1b ATP synthase F1 subunit beta decreases expression ISO Cocaine results in decreased expression of ATP5F1B protein CTD PMID:17075605 NCBI chr 7:515,454...521,858
Ensembl chr 7:515,460...567,273
JBrowse link
G Atp5f1e ATP synthase F1 subunit epsilon affects expression EXP Cocaine affects the expression of ATP5F1E mRNA CTD PMID:20187946 NCBI chr 3:163,259,072...163,261,974
Ensembl chr 3:163,260,476...163,261,450
JBrowse link
G Atp5mc3 ATP synthase membrane subunit c locus 3 decreases expression
affects expression
ISO
EXP
Cocaine results in decreased expression of ATP5MC3 mRNA
Cocaine affects the expression of ATP5MC3 mRNA
CTD PMID:12629581 PMID:20187946 NCBI chr 3:58,810,535...58,813,185
Ensembl chr 3:58,810,535...58,814,279
JBrowse link
G Atp5pb ATP synthase peripheral stalk-membrane subunit b affects expression EXP Cocaine affects the expression of ATP5PB mRNA CTD PMID:20187946 NCBI chr 2:193,424,138...193,435,418
Ensembl chr 2:193,424,047...193,435,418
JBrowse link
G Atp5pd ATP synthase peripheral stalk subunit d affects expression EXP Cocaine affects the expression of ATP5H mRNA CTD PMID:12358776 NCBI chr10:100,657,700...100,662,960
Ensembl chr10:100,657,708...100,663,479
JBrowse link
G Atp6v1d ATPase H+ transporting V1 subunit D affects expression EXP Cocaine affects the expression of ATP6V1D mRNA CTD PMID:20187946 NCBI chr 6:97,656,725...97,672,211
Ensembl chr 6:97,656,576...97,672,303
JBrowse link
G Atp8b2 ATPase phospholipid transporting 8B2 increases expression
multiple interactions
ISO Cocaine results in increased expression of ATP8B2 mRNA
FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of ATP8B2 mRNA]
CTD PMID:18355967 NCBI chr 2:175,378,514...175,402,265
Ensembl chr 2:175,378,517...175,401,883
JBrowse link
G Atp9b ATPase phospholipid transporting 9B (putative) affects response to substance ISO ATP9B gene SNP affects the susceptibility to Cocaine CTD PMID:18438686 NCBI chr18:74,176,863...74,368,993
Ensembl chr18:74,176,863...74,368,953
JBrowse link
G Atpaf1 ATP synthase mitochondrial F1 complex assembly factor 1 multiple interactions ISO [Cocaine co-treated with FOS protein mutant form] results in decreased expression of ATPAF1 mRNA CTD PMID:18355967 NCBI chr 5:129,265,789...129,293,556
Ensembl chr 5:129,266,404...129,293,556
JBrowse link
G Atrx ATRX, chromatin remodeler increases expression EXP Cocaine results in increased expression of ATRX mRNA CTD PMID:17898221 NCBI chr  X:70,850,981...70,997,330
Ensembl chr  X:70,850,981...70,997,330
JBrowse link
G Atxn1 ataxin 1 affects expression EXP Cocaine affects the expression of ATXN1 mRNA CTD PMID:20187946 NCBI chr17:18,737,491...19,142,360
Ensembl chr17:18,737,533...19,142,360
JBrowse link
G Atxn3 ataxin 3 decreases expression ISO Cocaine results in decreased expression of ATXN3 mRNA CTD PMID:12629581 NCBI chr 6:121,072,228...121,107,902
Ensembl chr 6:121,074,448...121,107,902
JBrowse link
G Azgp1 alpha-2-glycoprotein 1, zinc-binding decreases expression EXP Cocaine results in decreased expression of AZGP1 mRNA CTD PMID:17898221 NCBI chr12:16,930,990...16,939,333
Ensembl chr12:16,931,024...16,939,091
JBrowse link
G Baalc BAALC binder of MAP3K1 and KLF4 decreases expression ISO Cocaine results in decreased expression of BAALC mRNA CTD PMID:18355967 NCBI chr 7:69,918,998...69,992,289
Ensembl chr 7:69,918,998...69,992,288
JBrowse link
G Bach1 BTB domain and CNC homolog 1 increases expression EXP Cocaine results in increased expression of BACH1 mRNA CTD PMID:17898221 NCBI chr11:26,939,429...26,974,876
Ensembl chr11:26,939,480...26,972,447
JBrowse link
G Bach2 BTB domain and CNC homolog 2 affects expression ISO Cocaine affects the expression of BACH2 mRNA CTD PMID:15681117 NCBI chr 5:46,632,338...46,982,676
Ensembl chr 5:46,638,317...46,977,877
JBrowse link
G Bad BCL2-associated agonist of cell death affects expression ISO Cocaine affects the expression of BAD mRNA CTD PMID:15681117 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bag1 BAG cochaperone 1 affects expression ISO Cocaine affects the expression of BAG1 mRNA CTD PMID:15681117 NCBI chr 5:56,068,494...56,081,075
Ensembl chr 5:56,068,494...56,081,075
JBrowse link
G Bag3 BAG cochaperone 3 affects expression
increases expression
ISO
EXP
Cocaine affects the expression of BAG3 mRNA
Cocaine results in increased expression of BAG3 mRNA
CTD PMID:15681117 PMID:27899881 NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858
JBrowse link
G Bambi BMP and activin membrane-bound inhibitor affects expression EXP Cocaine affects the expression of BAMBI mRNA CTD PMID:20187946 NCBI chr17:54,121,251...54,125,816
Ensembl chr17:54,121,255...54,126,060
JBrowse link
G Basp1 brain abundant, membrane attached signal protein 1 affects expression EXP Cocaine affects the expression of BASP1 mRNA CTD PMID:20187946 NCBI chr 2:75,816,130...75,863,801
Ensembl chr 2:75,816,122...75,864,043
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions
increases activity
affects expression
ISO
EXP
Cocaine results in increased expression of BAX mRNA
ADCYAP1 protein modified form affects the reaction [Cocaine results in increased expression of BAX protein]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide affects the reaction [Cocaine results in increased expression of BAX protein]; IL6 protein affects the reaction [Cocaine results in increased expression of BAX protein]; TNF protein affects the reaction [Cocaine results in increased expression of BAX protein]; TNF protein affects the reaction [IL6 protein affects the reaction [Cocaine results in increased expression of BAX protein]]
Cocaine results in increased activity of BAX protein
Cocaine affects the expression of BAX mRNA
CTD PMID:11392460 PMID:15681117 PMID:15685203 PMID:17084983 PMID:17635674 More... NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Baz1b bromodomain adjacent to zinc finger domain, 1B multiple interactions
increases expression
ISO [SMARCA5 protein co-treated with BAZ1B protein] results in increased susceptibility to Cocaine; Cocaine promotes the reaction [BAZ1B protein binds to SPHKAP gene]; Cocaine results in increased expression of and affects the activity of BAZ1B protein
Cocaine results in increased expression of BAZ1B mRNA
CTD PMID:27053203 NCBI chr12:21,431,985...21,489,956
Ensembl chr12:21,431,985...21,490,426
JBrowse link
G Baz2b bromodomain adjacent to zinc finger domain, 2B increases expression EXP Cocaine results in increased expression of BAZ2B mRNA CTD PMID:17898221 NCBI chr 3:44,384,282...44,681,619
Ensembl chr 3:44,385,474...44,592,908
JBrowse link
G Bcap31 B-cell receptor-associated protein 31 affects expression EXP Cocaine affects the expression of BCAP31 mRNA CTD PMID:20187946 NCBI chr  X:151,397,567...151,429,666
Ensembl chr  X:151,397,576...151,428,506
JBrowse link
G Bcat1 branched chain amino acid transaminase 1 affects expression EXP Cocaine affects the expression of BCAT1 mRNA CTD PMID:20187946 NCBI chr 4:177,964,834...178,046,573
Ensembl chr 4:177,964,834...178,046,597
JBrowse link
G Bche butyrylcholinesterase affects metabolic processing
multiple interactions
increases hydrolysis
increases metabolic processing
decreases response to substance
affects hydrolysis
decreases metabolic processing
affects degradation
ISO BCHE protein affects the metabolism of Cocaine
[BCHE protein mutant form results in increased metabolism of Cocaine] which results in increased chemical synthesis of Benzoic Acid; [BCHE protein mutant form results in increased metabolism of Cocaine] which results in increased chemical synthesis of ecgonine methyl ester
[BCHE protein mutant form results in increased hydrolysis of Cocaine] which results in increased abundance of Benzoic Acid; [BCHE protein mutant form results in increased hydrolysis of Cocaine] which results in increased abundance of ecgonine methyl ester
BCHE protein mutant form results in increased metabolism of Cocaine; BCHE protein results in increased metabolism of Cocaine
BCHE protein mutant form results in decreased susceptibility to Cocaine
BCHE protein modified form results in increased hydrolysis of Cocaine; BCHE protein mutant form results in increased hydrolysis of Cocaine
BCHE protein affects the hydrolysis of Cocaine
BCHE protein mutant form results in decreased metabolism of Cocaine
BCHE protein mutant form affects the degradation of Cocaine
CTD PMID:572161 PMID:16275916 PMID:17989928 PMID:18514178 PMID:18514640 More... NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
JBrowse link
G Bcl11b BAF chromatin remodeling complex subunit BCL11B increases expression ISO Cocaine deficiency results in increased expression of BCL11B mRNA CTD PMID:27126842 NCBI chr 6:126,834,531...126,927,720
Ensembl chr 6:126,834,531...126,928,224
JBrowse link
G Bcl2 BCL2, apoptosis regulator affects expression
multiple interactions
decreases expression
increases phosphorylation
increases expression
ISO
EXP
Cocaine affects the expression of BCL2 mRNA
IL6 protein affects the reaction [Cocaine results in decreased expression of BCL2 protein]; PRKCD protein affects the reaction [Cocaine results in decreased expression of BCL2 protein]; rottlerin inhibits the reaction [Cocaine results in decreased expression of BCL2 protein]; TNF protein affects the reaction [Cocaine results in decreased expression of BCL2 protein]; TNF protein affects the reaction [IL6 protein affects the reaction [Cocaine results in decreased expression of BCL2 protein]]
Cocaine results in increased phosphorylation of BCL2 protein
6-methyl-2-(phenylethynyl)pyridine inhibits the reaction [Cocaine results in increased phosphorylation of BCL2 protein]; 7-(hydroxyimino)cyclopropan(b)chromen-1a-carbxoylic acid ethyl ester inhibits the reaction [Cocaine results in increased phosphorylation of BCL2 protein]; Dizocilpine Maleate inhibits the reaction [Cocaine results in increased phosphorylation of BCL2 protein]; ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate inhibits the reaction [Cocaine results in increased phosphorylation of BCL2 protein]; SCH 23390 inhibits the reaction [Cocaine results in increased phosphorylation of BCL2 protein]
Cocaine results in decreased expression of BCL2 mRNA; Cocaine results in decreased expression of BCL2 protein
Cocaine results in increased expression of BCL2 protein
CTD PMID:11392460 PMID:15365088 PMID:15681117 PMID:15685203 PMID:17084983 More... NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression
decreases expression
multiple interactions
EXP
ISO
Cocaine results in increased expression of BCL2L1 mRNA; Cocaine results in increased expression of BCL2L1 mRNA alternative form
Cocaine results in decreased expression of BCL2L1 protein
IL6 protein affects the reaction [Cocaine results in decreased expression of BCL2L1 protein]; PRKCD protein affects the reaction [Cocaine results in decreased expression of BCL2L1 protein]; rottlerin inhibits the reaction [Cocaine results in decreased expression of BCL2L1 protein]; TNF protein affects the reaction [Cocaine results in decreased expression of BCL2L1 protein]; TNF protein affects the reaction [IL6 protein affects the reaction [Cocaine results in decreased expression of BCL2L1 protein]]
CTD PMID:16076954 PMID:29673861 PMID:30393195 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bcl2l11 BCL2 like 11 increases expression EXP Cocaine results in increased expression of BCL2L11 mRNA CTD PMID:16076954 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
JBrowse link
G Bdnf brain-derived neurotrophic factor decreases response to substance
increases expression
decreases activity
affects expression
multiple interactions
decreases expression
increases response to substance
ISO
EXP
BDNF mRNA results in decreased susceptibility to Cocaine; BDNF protein results in decreased susceptibility to Cocaine
Cocaine results in increased expression of BDNF mRNA
Cocaine results in decreased activity of BDNF protein
Cocaine results in increased expression of BDNF protein
Cocaine affects the expression of BDNF exon; Cocaine affects the expression of BDNF mRNA; Cocaine affects the expression of BDNF protein
BDNF protein inhibits the reaction [Cocaine results in increased abundance of Amino Acids, Peptides, and Proteins]; Cocaine affects the activity of and affects the expression of BDNF protein; Cocaine affects the reaction [CREB1 modified form binds to BDNF promoter]; Cocaine affects the reaction [MECP2 protein affects the expression of BDNF protein]; Cocaine affects the reaction [MECP2 protein binds to and results in decreased activity of BDNF promoter]; Cocaine affects the reaction [MIR212 protein affects the expression of BDNF protein]
BDNF mRNA results in decreased susceptibility to Cocaine; BDNF protein results in decreased susceptibility to Cocaine; BDNF results in decreased susceptibility to Cocaine
(+)-JQ1 compound inhibits the reaction [Cocaine promotes the reaction [BRD4 protein binds to BDNF promoter]]; (+)-JQ1 compound inhibits the reaction [Cocaine results in increased expression of BDNF mRNA]; Cocaine inhibits the reaction [CREB1 protein binds to BDNF promoter]; Cocaine inhibits the reaction [MECP2 protein binds to BDNF promoter]; Cocaine promotes the reaction [BRD4 protein binds to BDNF promoter]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of BDNF mRNA]; Haloperidol inhibits the reaction [Cocaine results in decreased expression of BDNF protein]
Cocaine results in decreased expression of BDNF mRNA; Cocaine results in decreased expression of BDNF protein
BDNF results in increased susceptibility to Cocaine
CTD PMID:12099907 PMID:14973246 PMID:16423334 PMID:17194538 PMID:17618281 More... NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Begain brain-enriched guanylate kinase-associated affects expression EXP Cocaine affects the expression of BEGAIN mRNA CTD PMID:20187946 NCBI chr 6:127,943,651...127,979,876
Ensembl chr 6:127,943,651...127,979,841
JBrowse link
G Bhlhe22 basic helix-loop-helix family, member e22 increases expression EXP Cocaine results in increased expression of BHLHE22 mRNA CTD PMID:17898221 NCBI chr 2:100,486,400...100,489,510
Ensembl chr 2:100,486,400...100,489,510
JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 affects expression EXP Cocaine affects the expression of BHLHE40 mRNA CTD PMID:20187946 NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774
JBrowse link
G Bid BH3 interacting domain death agonist affects expression ISO Cocaine affects the expression of BID mRNA CTD PMID:15681117 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Bik BCL2-interacting killer affects expression ISO Cocaine affects the expression of BIK mRNA CTD PMID:15681117 NCBI chr 7:114,672,277...114,691,296
Ensembl chr 7:114,672,277...114,691,296
JBrowse link
G Bmp2k BMP-2 inducible kinase affects expression EXP Cocaine affects the expression of BMP2K mRNA CTD PMID:20187946 NCBI chr14:12,481,194...12,579,411
Ensembl chr14:12,484,729...12,579,134
JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 increases expression EXP Cocaine results in increased expression of BMPR2 mRNA CTD PMID:17898221 NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809
JBrowse link
G Bnip2 BCL2 interacting protein 2 affects expression ISO Cocaine affects the expression of BNIP2 mRNA CTD PMID:15681117 NCBI chr 8:70,640,436...70,661,782
Ensembl chr 8:70,640,445...70,675,590
JBrowse link
G Bnip3 BCL2 interacting protein 3 affects expression ISO Cocaine affects the expression of BNIP3 mRNA CTD PMID:15681117 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
JBrowse link
G Bnip3l BCL2 interacting protein 3 like affects expression ISO Cocaine affects the expression of BNIP3L mRNA CTD PMID:15681117 NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803
JBrowse link
G Brd4 bromodomain containing 4 multiple interactions
increases expression
ISO
EXP
(+)-JQ1 compound inhibits the reaction [Cocaine promotes the reaction [BRD4 protein binds to BDNF promoter]]; Cocaine promotes the reaction [BRD4 protein binds to BDNF promoter]
Cocaine results in increased expression of BRD4 protein
CTD PMID:26558777 NCBI chr 7:11,216,446...11,296,029
Ensembl chr 7:11,216,446...11,295,539
JBrowse link
G Bscl2 BSCL2 lipid droplet biogenesis associated, seipin affects expression EXP Cocaine affects the expression of BSCL2 mRNA CTD PMID:20187946 NCBI chr 1:205,731,814...205,743,430
Ensembl chr 1:205,733,872...205,743,421
JBrowse link
G Bst1 bone marrow stromal cell antigen 1 affects expression EXP Cocaine affects the expression of BST1 mRNA CTD PMID:20187946 NCBI chr14:67,253,706...67,270,203
Ensembl chr14:67,252,998...67,270,180
JBrowse link
G Btbd9 BTB domain containing 9 increases expression EXP Cocaine results in increased expression of BTBD9 mRNA CTD PMID:17898221 NCBI chr20:8,286,337...8,645,567
Ensembl chr20:8,288,711...8,643,960
JBrowse link
G Btg2 BTG anti-proliferation factor 2 affects expression EXP Cocaine affects the expression of BTG2 mRNA CTD PMID:20187946 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
JBrowse link
G Btk Bruton tyrosine kinase decreases expression EXP Cocaine results in decreased expression of BTK mRNA CTD PMID:17898221 NCBI chr  X:97,722,796...97,762,315
Ensembl chr  X:97,722,802...97,761,853
JBrowse link
G C1qbp complement C1q binding protein decreases expression EXP Cocaine results in decreased expression of C1QBP protein CTD PMID:25100957 NCBI chr10:55,699,954...55,704,605
Ensembl chr10:55,699,954...55,704,649
JBrowse link
G C1qtnf1 C1q and TNF related 1 affects expression EXP Cocaine affects the expression of C1QTNF1 mRNA CTD PMID:20187946 NCBI chr10:103,660,319...103,681,662
Ensembl chr10:103,660,327...103,681,660
JBrowse link
G C1qtnf4 C1q and TNF related 4 decreases expression EXP Cocaine results in decreased expression of C1QTNF4 mRNA CTD PMID:17898221 NCBI chr 3:76,854,368...76,872,991
Ensembl chr 3:76,857,735...76,874,139
JBrowse link
G C2cd3 C2 domain containing 3 centriole elongation regulator decreases expression EXP Cocaine results in decreased expression of C2CD3 mRNA CTD PMID:17898221 NCBI chr 1:154,715,151...154,812,955
Ensembl chr 1:154,715,310...154,812,520
JBrowse link
G C2cd4d C2 calcium-dependent domain containing 4D decreases expression EXP Cocaine results in decreased expression of C2CD4D mRNA CTD PMID:27899881 NCBI chr 2:181,997,393...182,001,938
Ensembl chr 2:181,997,078...182,002,087
JBrowse link
G Ca4 carbonic anhydrase 4 decreases expression EXP Cocaine results in decreased expression of CAR4 mRNA CTD PMID:17898221 NCBI chr10:69,827,945...69,836,501
Ensembl chr10:69,827,945...69,836,501
JBrowse link
G Cab39l calcium binding protein 39-like multiple interactions ISO [Cocaine co-treated with FOS protein mutant form] results in increased expression of CAB39L mRNA CTD PMID:18355967 NCBI chr15:33,606,588...33,710,518
Ensembl chr15:33,606,694...33,743,545
JBrowse link
G Cacna1d calcium voltage-gated channel subunit alpha1 D affects response to substance ISO CACNA1D polymorphism affects the susceptibility to Cocaine CTD PMID:28194001 NCBI chr16:5,227,157...5,521,163
Ensembl chr16:5,228,306...5,668,215
JBrowse link
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 affects expression EXP Cocaine affects the expression of CACNB3 mRNA CTD PMID:20187946 NCBI chr 7:129,784,799...129,797,074
Ensembl chr 7:129,783,674...129,797,074
JBrowse link
G Cald1 caldesmon 1 affects expression EXP Cocaine affects the expression of CALD1 mRNA CTD PMID:20187946 NCBI chr 4:63,265,781...63,446,936
Ensembl chr 4:63,265,942...63,446,932
JBrowse link
G Calm1 calmodulin 1 decreases expression ISO Cocaine results in decreased expression of CALM1 mRNA CTD PMID:17205118 NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227
JBrowse link
G Calm2 calmodulin 2 decreases expression ISO Cocaine results in decreased expression of CALM2 mRNA CTD PMID:17205118 NCBI chr 6:7,091,624...7,104,284
Ensembl chr 6:7,091,567...7,104,287
JBrowse link
G Calr calreticulin decreases expression
multiple interactions
affects expression
ISO
EXP
Cocaine results in decreased expression of CALR mRNA
FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of CALR mRNA]
Cocaine affects the expression of CALR mRNA
CTD PMID:18355967 PMID:20187946 NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414
JBrowse link
G Caly calcyon neuron-specific vesicular protein increases expression EXP Cocaine results in increased expression of CALY mRNA CTD PMID:20171207 NCBI chr 1:194,862,671...194,873,861
Ensembl chr 1:194,862,672...194,873,551
JBrowse link
G Camk1g calcium/calmodulin-dependent protein kinase IG multiple interactions ISO [Cocaine co-treated with FOS protein mutant form] results in increased expression of CAMK1G mRNA CTD PMID:18355967 NCBI chr13:104,877,909...104,901,658
Ensembl chr13:104,877,910...104,901,556
JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha affects response to substance
multiple interactions
increases expression
ISO
EXP
CAMK2A affects the susceptibility to Cocaine
Cocaine results in increased expression of and results in increased phosphorylation of CAMK2A protein; Nifedipine inhibits the reaction [Cocaine results in increased expression of and results in increased phosphorylation of CAMK2A protein]
Cocaine results in increased expression of CAMK2A protein
7-chlorokynurenic acid inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of CAMK2A protein]; Cocaine promotes the reaction [DRD3 protein binds to CAMK2A protein]; Cocaine results in increased phosphorylation of and results in increased activity of CAMK2A protein; KN 93 inhibits the reaction [Cocaine promotes the reaction [DRD3 protein binds to CAMK2A protein]]; Sodium Benzoate promotes the reaction [Cocaine results in increased phosphorylation of and results in increased activity of CAMK2A protein]
CTD PMID:14725635 PMID:17609678 PMID:19217379 PMID:28194001 NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994
JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta decreases expression
affects expression
ISO
EXP
Cocaine results in decreased expression of CAMK2B mRNA
Cocaine affects the expression of CAMK2B mRNA
CTD PMID:17205118 PMID:20187946 NCBI chr14:80,845,206...80,934,172
Ensembl chr14:80,845,238...80,933,994
JBrowse link
G Camk4 calcium/calmodulin-dependent protein kinase IV increases response to substance
decreases response to substance
ISO CAMK4 promoter SNP results in increased susceptibility to Cocaine
CAMK4 protein results in decreased susceptibility to Cocaine
CTD PMID:19001277 NCBI chr18:24,582,988...24,811,918
Ensembl chr18:24,585,269...24,802,487
JBrowse link
G Cap2 cyclase associated actin cytoskeleton regulatory protein 2 affects expression EXP Cocaine affects the expression of CAP2 mRNA CTD PMID:20187946 NCBI chr17:18,054,234...18,203,453
Ensembl chr17:18,054,431...18,203,373
JBrowse link
G Capzb capping actin protein of muscle Z-line subunit beta decreases expression ISO Cocaine results in decreased expression of CAPZB mRNA CTD PMID:12629581 NCBI chr 5:151,435,600...151,535,409
Ensembl chr 5:151,434,871...151,535,409
JBrowse link
G Card11 caspase recruitment domain family, member 11 decreases expression EXP Cocaine results in decreased expression of CARD11 mRNA CTD PMID:27899881 NCBI chr12:13,620,979...13,758,115
Ensembl chr12:13,621,087...13,758,112
JBrowse link
G Carm1 coactivator-associated arginine methyltransferase 1 affects expression EXP Cocaine affects the expression of CARM1 mRNA CTD PMID:20187946 NCBI chr 8:20,097,262...20,141,950
Ensembl chr 8:20,097,254...20,147,689
JBrowse link
G Carnmt1 carnosine N-methyltransferase 1 affects expression EXP Cocaine affects the expression of CARNMT1 mRNA CTD PMID:20187946 NCBI chr 1:216,093,720...216,123,360
Ensembl chr 1:216,093,695...216,121,006
JBrowse link
G Cartpt CART prepropeptide increases expression
affects expression
ISO
EXP
Cocaine results in increased expression of CARTPT mRNA
Cocaine affects the expression of CARTPT mRNA
CTD PMID:15009677 PMID:17851536 PMID:20187946 NCBI chr 2:31,255,098...31,257,452
Ensembl chr 2:31,255,098...31,290,713
JBrowse link
G Casp2 caspase 2 increases activity
increases expression
EXP Cocaine results in increased activity of CASP2 protein
Cocaine results in increased expression of CASP2 mRNA
CTD PMID:16076954 PMID:16638611 NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379
JBrowse link
G Casp3 caspase 3 increases expression
increases cleavage
multiple interactions
increases activity
affects expression
ISO
EXP
Cocaine results in increased expression of CASP3 protein
Cocaine results in increased cleavage of CASP3 protein
ADCYAP1 protein modified form affects the reaction [Cocaine results in increased cleavage of CASP3 protein]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide affects the reaction [Cocaine results in increased cleavage of CASP3 protein]; IL6 protein affects the reaction [Cocaine results in increased cleavage of CASP3 protein]; PRKCD protein affects the reaction [Cocaine results in increased cleavage of CASP3 protein]; rottlerin inhibits the reaction [Cocaine results in increased cleavage of CASP3 protein]; TNF protein affects the reaction [Cocaine results in increased cleavage of CASP3 protein]; TNF protein affects the reaction [IL6 protein affects the reaction [Cocaine results in increased cleavage of CASP3 protein]]
Cocaine results in increased activity of CASP3 protein
Cocaine affects the expression of CASP3 protein
[Heroin co-treated with Cocaine] results in increased activity of CASP3 protein; Cocaine results in increased cleavage of and results in increased activity of CASP3 protein; Heroin promotes the reaction [Cocaine results in increased activity of CASP3 protein]; SB 203580 inhibits the reaction [Cocaine results in increased activity of CASP3 protein]
Cocaine affects the expression of CASP3 mRNA
CTD PMID:10604926 PMID:11392460 PMID:12639677 PMID:14741756 PMID:15365088 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp4 caspase 4 affects expression
decreases expression
ISO Cocaine affects the expression of CASP4 mRNA
Cocaine results in decreased expression of CASP4 mRNA
CTD PMID:12629581 PMID:15681117 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
JBrowse link
G Casp8 caspase 8 affects expression
increases activity
ISO
EXP
Cocaine affects the expression of CASP8 mRNA
Cocaine results in increased activity of CASP8 protein
CTD PMID:11392460 PMID:15681117 PMID:18974856 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 affects expression
increases activity
multiple interactions
increases expression
ISO
EXP
Cocaine affects the expression of CASP9 mRNA
Cocaine results in increased activity of CASP9 protein
SB 203580 inhibits the reaction [Cocaine results in increased activity of CASP9 protein]
Cocaine affects the expression of CASP9 protein
Cocaine results in increased expression of CASP9 protein
CTD PMID:10604926 PMID:11392460 PMID:12639677 PMID:15365088 PMID:15681117 More... NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Castor1 cytosolic arginine sensor for mTORC1 subunit 1 affects expression EXP Cocaine affects the expression of CASTOR1 mRNA CTD PMID:20187946 NCBI chr14:79,086,136...79,090,549
Ensembl chr14:79,086,136...79,090,548
JBrowse link
G Cat catalase decreases activity
increases activity
increases expression
ISO
EXP
Cocaine results in decreased activity of CAT protein
Cocaine results in increased activity of CAT protein
Cocaine results in increased expression of CAT protein
CTD PMID:14576513 PMID:16085363 PMID:29475069 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Catsper2 cation channel, sperm associated 2 increases expression EXP Cocaine results in increased expression of CATSPER2 mRNA CTD PMID:17898221 NCBI chr 3:108,368,654...108,389,380
Ensembl chr 3:108,368,668...108,388,050
JBrowse link
G Cbln1 cerebellin 1 precursor multiple interactions ISO [Cocaine co-treated with FOS protein mutant form] results in increased expression of CBLN1 mRNA CTD PMID:18355967 NCBI chr19:19,608,763...19,612,572
Ensembl chr19:19,608,716...19,612,572
JBrowse link
G Ccdc127 coiled-coil domain containing 127 increases expression EXP Cocaine results in increased expression of CCDC127 mRNA CTD PMID:17898221 NCBI chr 1:28,928,420...28,935,885
Ensembl chr 1:28,928,325...28,935,893
JBrowse link
G Ccdc174 coiled-coil domain containing 174 affects expression EXP Cocaine affects the expression of CCDC174 mRNA CTD PMID:20187946 NCBI chr 4:124,392,183...124,419,035
Ensembl chr 4:124,392,274...124,419,035
JBrowse link
G Ccdc73 coiled-coil domain containing 73 decreases expression EXP Cocaine results in decreased expression of CCDC73 mRNA CTD PMID:17898221 NCBI chr 3:91,282,919...91,424,269
Ensembl chr 3:91,282,940...91,424,551
JBrowse link
G Ccdc88a coiled coil domain containing 88A increases expression EXP Cocaine results in increased expression of CCDC88A mRNA CTD PMID:17898221 NCBI chr14:103,104,091...103,256,112
Ensembl chr14:103,103,513...103,252,368
JBrowse link
G Ccdc93 coiled-coil domain containing 93 increases expression EXP Cocaine results in increased expression of CCDC93 mRNA CTD PMID:17898221 NCBI chr13:32,607,618...32,675,993
Ensembl chr13:32,607,587...32,676,023
JBrowse link
G Cckbr cholecystokinin B receptor decreases expression
increases response to substance
ISO Cocaine results in decreased expression of CCKBR mRNA
CCKBR protein results in increased susceptibility to Cocaine
CTD PMID:11403953 PMID:18000554 NCBI chr 1:159,771,733...159,781,738
Ensembl chr 1:159,771,733...159,814,881
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases secretion
increases expression
multiple interactions
ISO
EXP
Cocaine results in increased secretion of CCL2 protein
Cocaine results in increased expression of CCL2 mRNA; Cocaine results in increased expression of CCL2 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; AG 1879 inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; Cocaine promotes the reaction [RELA protein binds to CCL2 promoter]; methyl-beta-cyclodextrin inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; N-(2-(3,4-Dichlorphenyl)ethyl)-N,N',N'-trimethyl-1,2-ethandiamin inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; pyrazolanthrone inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; RELA mutant form inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; SC 514 inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; SIGMAR1 mutant form inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; U 0126 inhibits the reaction [Cocaine results in increased expression of CCL2 protein]
CTD PMID:10065903 PMID:20354174 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases secretion ISO Cocaine results in increased secretion of CCL3 protein CTD PMID:10065903 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Ccn2 cellular communication network factor 2 decreases expression ISO Cocaine results in decreased expression of CCN2 mRNA; Cocaine results in decreased expression of CCN2 protein CTD PMID:18000554 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
JBrowse link
G Ccn3 cellular communication network factor 3 increases expression EXP Cocaine results in increased expression of CCN3 mRNA CTD PMID:17898221 NCBI chr 7:86,094,000...86,101,022
Ensembl chr 7:86,094,000...86,101,019
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO
EXP
Cocaine results in decreased expression of CCNA2 mRNA CTD PMID:18593214 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnd1 cyclin D1 affects expression EXP Cocaine affects the expression of CCND1 mRNA CTD PMID:20187946 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccnd3 cyclin D3 affects expression EXP Cocaine affects the expression of CCND3 mRNA CTD PMID:20187946 NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371
JBrowse link
G Ccnl1 cyclin L1 increases expression EXP Cocaine results in increased expression of CCNL1 mRNA CTD PMID:16076954 NCBI chr 2:150,184,865...150,199,524
Ensembl chr 2:150,184,798...150,197,368
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 affects expression
increases response to substance
EXP
ISO
Cocaine affects the expression of CCR2 mRNA
CCR2 results in increased susceptibility to Cocaine
CTD PMID:20187946 PMID:20354174 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100
JBrowse link
G Ccr5 C-C motif chemokine receptor 5 increases expression ISO Cocaine results in increased expression of CCR5 protein CTD PMID:16204638 NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260
JBrowse link
G Ccser1 coiled-coil serine-rich protein 1 affects response to substance ISO CCSER1 gene SNP affects the susceptibility to Cocaine CTD PMID:18438686 NCBI chr 4:90,153,873...91,391,441
Ensembl chr 4:90,292,780...91,388,786
JBrowse link
G Cct2 chaperonin containing TCP1 subunit 2 affects expression EXP Cocaine affects the expression of CCT2 mRNA CTD PMID:20187946 NCBI chr 7:52,692,725...52,705,478
Ensembl chr 7:52,692,725...52,706,944
JBrowse link
G Cd180 CD180 molecule decreases expression EXP Cocaine results in decreased expression of CD180 mRNA CTD PMID:27899881 NCBI chr 2:33,855,940...33,870,046
Ensembl chr 2:33,855,991...33,899,936
JBrowse link
G Cd276 Cd276 molecule affects expression EXP Cocaine affects the expression of CD276 mRNA CTD PMID:20187946 NCBI chr 8:58,937,751...58,968,082
Ensembl chr 8:58,937,751...58,968,380
JBrowse link
G Cd4 Cd4 molecule multiple interactions ISO [Cocaine co-treated with FOS protein mutant form] results in decreased expression of CD4 mRNA CTD PMID:18355967 NCBI chr 4:157,668,878...157,695,366 JBrowse link
G Cd44 CD44 molecule (Indian blood group) decreases expression ISO Cocaine results in decreased expression of CD44 mRNA CTD PMID:18000554 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Cd47 Cd47 molecule affects expression EXP Cocaine affects the expression of CD47 mRNA CTD PMID:20187946 NCBI chr11:50,906,052...50,970,000
Ensembl chr11:50,906,177...50,969,425
JBrowse link
G Cd74 CD74 molecule affects expression EXP Cocaine affects the expression of CD74 mRNA CTD PMID:20187946 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003
JBrowse link
G Cd81 Cd81 molecule increases response to substance
increases expression
affects response to substance
ISO
EXP
CD81 protein results in increased susceptibility to Cocaine
Cocaine results in increased expression of CD81 mRNA
CD81 protein affects the susceptibility to Cocaine
CTD PMID:11178868 PMID:12113778 PMID:15715673 NCBI chr 1:198,235,861...198,251,660
Ensembl chr 1:198,241,484...198,251,660
JBrowse link
G Cd93 CD93 molecule decreases expression EXP Cocaine results in decreased expression of CD93 mRNA CTD PMID:17898221 NCBI chr 3:135,891,859...135,898,378
Ensembl chr 3:135,891,859...135,898,378
JBrowse link
G Cdc14b cell division cycle 14B decreases expression EXP Cocaine results in decreased expression of CDC14B mRNA CTD PMID:17898221 NCBI chr17:844,731...934,787
Ensembl chr17:844,685...933,235
JBrowse link
G Cdc25a cell division cycle 25A increases expression EXP Cocaine results in increased expression of CDC25A mRNA CTD PMID:17898221 NCBI chr 8:109,864,356...109,882,734
Ensembl chr 8:109,864,478...109,882,701
JBrowse link
G Cdh1 cadherin 1 decreases expression ISO Cocaine results in decreased expression of CDH1 mRNA CTD PMID:12629581 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cdh16 cadherin 16 affects expression EXP Cocaine affects the expression of CDH16 mRNA CTD PMID:20187946 NCBI chr19:360,824...371,008
Ensembl chr19:360,824...371,007
JBrowse link
G Cdh17 cadherin 17 decreases expression ISO Cocaine results in decreased expression of CDH17 mRNA CTD PMID:12629581 NCBI chr 5:25,262,820...25,314,884
Ensembl chr 5:25,262,758...25,314,884
JBrowse link
G Cdk18 cyclin-dependent kinase 18 affects expression EXP Cocaine affects the expression of CDK18 mRNA CTD PMID:20187946 NCBI chr13:43,555,597...43,582,210
Ensembl chr13:43,556,748...43,588,525
JBrowse link
G Cdk4 cyclin-dependent kinase 4 affects expression ISO Cocaine affects the expression of CDK4 mRNA CTD PMID:18355967 NCBI chr 7:62,885,647...62,889,562
Ensembl chr 7:62,883,105...62,942,403
JBrowse link
G Cdk5 cyclin-dependent kinase 5 affects expression
increases expression
decreases expression
EXP Cocaine affects the expression of CDK5 mRNA; Cocaine affects the expression of CDK5 protein
Cocaine results in increased expression of CDK5 mRNA; Cocaine results in increased expression of CDK5 protein
Cocaine results in decreased expression of CDK5 protein
CTD PMID:11268215 PMID:12787079 PMID:16263094 PMID:17339080 PMID:17680995 More... NCBI chr 4:10,754,682...10,760,110
Ensembl chr 4:10,754,687...10,760,112
JBrowse link
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 multiple interactions
increases expression
decreases expression
ISO
EXP
CDK5R1 protein inhibits the reaction [Cocaine affects the expression of FOS mRNA]; CDK5R1 protein inhibits the reaction [Cocaine results in increased expression of FOS protein]; CDK5R1 protein inhibits the reaction [Cocaine results in increased phosphorylation of CREB1 protein]; CDK5R1 protein inhibits the reaction [Cocaine results in increased phosphorylation of MAP2K1 protein]; CDK5R1 protein inhibits the reaction [Cocaine results in increased phosphorylation of MAP2K2 protein]; CDK5R1 protein inhibits the reaction [Cocaine results in increased phosphorylation of MAPK1 protein]; CDK5R1 protein inhibits the reaction [Cocaine results in increased phosphorylation of MAPK3 protein]; CDK5R1 protein inhibits the reaction [Cocaine results in increased phosphorylation of PPP1R1B protein]
Cocaine results in increased expression of CDK5R1 mRNA; Cocaine results in increased expression of CDK5R1 protein
Cocaine results in decreased expression of CDK5R1 protein
CTD PMID:11268215 PMID:15665076 PMID:16263094 NCBI chr10:65,484,266...65,485,467
Ensembl chr10:65,483,941...65,488,456
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression EXP Cocaine results in increased expression of CDKN1A mRNA CTD PMID:27899881 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Ceacam4 CEA cell adhesion molecule 4 affects expression EXP Cocaine affects the expression of CEACAM3 mRNA CTD PMID:20187946 NCBI chr 1:80,376,667...80,382,943
Ensembl chr 1:80,376,648...80,382,915
JBrowse link
G Cel carboxyl ester lipase increases expression EXP Cocaine results in increased expression of CEL mRNA CTD PMID:27899881 NCBI chr 3:11,883,532...11,891,035
Ensembl chr 3:11,883,532...11,891,035
JBrowse link
G Ces1d carboxylesterase 1D multiple interactions
increases hydrolysis
affects binding
ISO CES1 protein results in increased metabolism of [Cocaine co-treated with Ethanol]; Cocaine inhibits the reaction [CES1 protein results in increased chemical synthesis of 6-O-monoacetylmorphine]; Cocaine inhibits the reaction [CES1 protein results in increased hydrolysis of 4-methylumbelliferyl acetate]; Cocaine inhibits the reaction [CES1 protein results in increased hydrolysis of Heroin]
CES1 protein results in increased hydrolysis of Cocaine
Cocaine binds to CES1 protein
CTD PMID:8930175 PMID:9311626 PMID:12679808 PMID:12773168 PMID:25445008 NCBI chr19:13,873,490...13,912,035 JBrowse link
G Ces2h carboxylesterase 2H multiple interactions
decreases expression
increases hydrolysis
ISO Cocaine inhibits the reaction [CES2 protein results in increased chemical synthesis of 6-O-monoacetylmorphine]; Cocaine inhibits the reaction [CES2 protein results in increased chemical synthesis of Morphine]; Cocaine inhibits the reaction [CES2 protein results in increased hydrolysis of 6-O-monoacetylmorphine]; Cocaine inhibits the reaction [CES2 protein results in increased hydrolysis of Heroin]
Cocaine results in decreased expression of CES2 mRNA
CES2 protein results in increased hydrolysis of Cocaine
CTD PMID:8930175 PMID:9169443 PMID:12629581 NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830
JBrowse link
G Cfh complement factor H decreases expression EXP Cocaine results in decreased expression of CFH mRNA CTD PMID:17898221 NCBI chr13:51,512,376...51,613,829
Ensembl chr13:51,511,828...51,613,838
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator affects expression ISO Cocaine affects the expression of CFLAR mRNA CTD PMID:15681117 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
JBrowse link
G Chfr checkpoint with forkhead and ring finger domains affects expression EXP Cocaine affects the expression of CHFR mRNA CTD PMID:20187946 NCBI chr12:46,504,497...46,538,104
Ensembl chr12:46,504,497...46,538,014
JBrowse link
G Chn1 chimerin 1 affects expression EXP Cocaine affects the expression of CHN1 mRNA CTD PMID:20187946 NCBI chr 3:58,509,822...58,676,774
Ensembl chr 3:58,510,536...58,676,490
JBrowse link
G Chrm4 cholinergic receptor, muscarinic 4 affects expression EXP Cocaine affects the expression of CHRM4 mRNA CTD PMID:20187946 NCBI chr 3:77,893,425...77,901,166
Ensembl chr 3:77,893,425...77,901,159
JBrowse link
G Chrm5 cholinergic receptor, muscarinic 5 decreases response to substance EXP CHRM5 mutant form results in decreased susceptibility to Cocaine CTD PMID:20393457 NCBI chr 3:99,284,846...99,337,252
Ensembl chr 3:99,284,846...99,337,252
JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit multiple interactions EXP Cocaine inhibits the reaction [Nicotine results in increased activity of [CHRNA3 protein binds to CHRNB2 protein]] CTD PMID:10336510 NCBI chr 8:55,401,981...55,415,012
Ensembl chr 8:55,401,702...55,415,165
JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions EXP Cocaine inhibits the reaction [Nicotine results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]] CTD PMID:10336510 NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957
JBrowse link
G Chrna5 cholinergic receptor nicotinic alpha 5 subunit decreases response to substance ISO CHRNA5 gene polymorphism results in decreased susceptibility to Cocaine CTD PMID:18519132 NCBI chr 8:55,369,794...55,398,526
Ensembl chr 8:55,369,794...55,398,146
JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit multiple interactions
increases response to substance
EXP
ISO
Cocaine inhibits the reaction [Nicotine results in increased activity of [CHRNA3 protein binds to CHRNB2 protein]]; Cocaine inhibits the reaction [Nicotine results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]]
CHRNB2 protein results in increased susceptibility to Cocaine
CTD PMID:10336510 PMID:11282258 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619
JBrowse link
G Chrne cholinergic receptor nicotinic epsilon subunit increases expression EXP Cocaine results in increased expression of CHRNE mRNA CTD PMID:27899881 NCBI chr10:55,331,211...55,339,923
Ensembl chr10:55,331,212...55,335,530
JBrowse link
G Chtf8 chromosome transmission fidelity factor 8 decreases expression EXP Cocaine results in decreased expression of CHTF8 mRNA CTD PMID:17898221 NCBI chr19:34,782,005...34,792,306
Ensembl chr19:34,781,856...34,792,578
JBrowse link
G Churc1 churchill domain containing 1 decreases expression ISO Cocaine results in decreased expression of CHURC1 mRNA CTD PMID:15009677 PMID:16710320 NCBI chr 6:95,464,488...95,485,208 JBrowse link
G Ciao1 cytosolic iron-sulfur assembly component 1 affects expression EXP Cocaine affects the expression of CIAO1 mRNA CTD PMID:20187946 NCBI chr 3:114,458,671...114,465,928
Ensembl chr 3:114,458,655...114,467,009
JBrowse link
G Cidea cell death-inducing DFFA-like effector a affects expression ISO Cocaine affects the expression of CIDEA mRNA CTD PMID:15681117 NCBI chr18:60,894,917...60,920,485
Ensembl chr18:60,894,874...60,920,481
JBrowse link
G Cideb cell death-inducing DFFA-like effector b affects expression ISO Cocaine affects the expression of CIDEB mRNA CTD PMID:15681117 NCBI chr15:29,252,203...29,256,759
Ensembl chr15:29,252,213...29,256,605
JBrowse link
G Cisd1 CDGSH iron sulfur domain 1 increases expression EXP Cocaine results in increased expression of CISD1 protein CTD PMID:25100957 NCBI chr20:17,255,302...17,268,688
Ensembl chr20:17,255,151...17,284,924
JBrowse link
G Cisd2 CDGSH iron sulfur domain 2 increases expression EXP Cocaine results in increased expression of CISD2 mRNA CTD PMID:17898221 NCBI chr 2:223,828,937...223,853,768
Ensembl chr 2:223,828,937...223,868,946
JBrowse link
G Cited4 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4 decreases expression EXP Cocaine results in decreased expression of CITED4 mRNA CTD PMID:27899881 NCBI chr 5:134,246,936...134,247,827
Ensembl chr 5:134,246,682...134,248,135
JBrowse link
G Ckb creatine kinase B multiple interactions ISO Cocaine results in increased secretion of [CKB protein binds to CKM protein] CTD PMID:12359538 NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315
JBrowse link
G Ckm creatine kinase, M-type multiple interactions ISO Cocaine results in increased secretion of [CKB protein binds to CKM protein] CTD PMID:12359538 NCBI chr 1:79,061,390...79,071,721
Ensembl chr 1:79,061,456...79,071,720
JBrowse link
G Ckmt1 creatine kinase, mitochondrial 1 affects expression EXP Cocaine affects the expression of CKMT1 mRNA CTD PMID:20187946 NCBI chr 3:108,329,859...108,335,760
Ensembl chr 3:108,330,705...108,335,758
JBrowse link
G Clcn7 chloride voltage-gated channel 7 affects expression EXP Cocaine affects the expression of CLCN7 mRNA CTD PMID:20187946 NCBI chr10:14,151,758...14,177,130
Ensembl chr10:14,151,758...14,177,130
JBrowse link
G Cldn11 claudin 11 decreases expression ISO Cocaine results in decreased expression of CLDN11 mRNA CTD PMID:18357522 NCBI chr 2:112,207,745...112,221,050
Ensembl chr 2:112,207,745...112,221,050
JBrowse link
G Clec4f C-type lectin domain family 4, member F affects expression EXP Cocaine affects the expression of CLEC4F mRNA CTD PMID:20187946 NCBI chr 4:116,129,023...116,138,744
Ensembl chr 4:116,129,023...116,138,775
JBrowse link
G Clic1 chloride intracellular channel 1 decreases expression ISO Cocaine results in decreased expression of CLIC1 mRNA CTD PMID:18000554 NCBI chr20:3,764,867...3,773,711
Ensembl chr20:3,761,461...3,773,712
JBrowse link
G Clip1 CAP-GLY domain containing linker protein 1 increases expression ISO Cocaine results in increased expression of CLIP1 mRNA CTD PMID:18000554 NCBI chr12:32,910,932...33,017,891
Ensembl chr12:32,910,977...33,017,884
JBrowse link
G Clk1 CDC-like kinase 1 increases expression
multiple interactions
ISO Cocaine results in increased expression of CLK1 mRNA
FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of CLK1 mRNA]
CTD PMID:18355967 NCBI chr 9:59,947,774...59,959,002
Ensembl chr 9:59,947,764...59,957,000
JBrowse link
G Clk4 CDC-like kinase 4 increases expression ISO Cocaine results in increased expression of CLK4 mRNA CTD PMID:20056891 NCBI chr10:35,523,382...35,541,387
Ensembl chr10:35,524,755...35,541,352
JBrowse link
G Clock clock circadian regulator increases expression ISO Cocaine results in increased expression of CLOCK mRNA CTD PMID:15994025 NCBI chr14:31,908,542...31,992,673
Ensembl chr14:31,908,566...31,990,400
JBrowse link
G Cltb clathrin, light chain B decreases expression ISO Cocaine results in decreased expression of CLTB mRNA CTD PMID:12629581 PMID:15009677 NCBI chr17:10,001,512...10,019,201
Ensembl chr17:10,001,513...10,019,169
JBrowse link
G Clybl citramalyl-CoA lyase increases expression EXP Cocaine results in increased expression of CLYBL protein CTD PMID:25100957 NCBI chr15:99,283,644...99,505,697
Ensembl chr15:99,283,650...99,505,695
JBrowse link
G Cnbd2 cyclic nucleotide binding domain containing 2 increases expression EXP Cocaine results in increased expression of CNBD2 mRNA CTD PMID:17898221 NCBI chr 3:144,819,166...144,884,825
Ensembl chr 3:144,819,195...144,901,583
JBrowse link
G Cnksr2 connector enhancer of kinase suppressor of Ras 2 increases expression ISO Cocaine results in increased expression of CNKSR2 mRNA CTD PMID:15009677 NCBI chr  X:36,908,135...37,148,337
Ensembl chr  X:36,907,850...37,150,555
JBrowse link
G Cnr1 cannabinoid receptor 1 affects response to substance
increases activity
decreases response to substance
multiple interactions
ISO CNR1 gene polymorphism affects the susceptibility to Cocaine; CNR1 gene SNP affects the susceptibility to Cocaine; CNR1 polymorphism affects the susceptibility to Cocaine
Cocaine results in increased activity of CNR1 protein
CNR1 mutant form results in decreased susceptibility to Cocaine
CNR1 gene mutant form inhibits the reaction [Cocaine results in increased phosphorylation of PPP1R1B protein]; CNR1 mutant form inhibits the reaction [Cocaine results in increased expression of FOS protein]; CNR1 mutant form inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein]; CNR1 mutant form inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein]
CTD PMID:9106242 PMID:16314880 PMID:17596442 PMID:19052543 PMID:20554863 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
JBrowse link
G Cnr2 cannabinoid receptor 2 increases expression ISO Cocaine results in increased expression of CNR2 mRNA CTD PMID:18286196 NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548
JBrowse link
G Cobll1 cordon-bleu WH2 repeat protein-like 1 increases expression ISO Cocaine results in increased expression of COBLL1 mRNA CTD PMID:27506785 NCBI chr 3:49,753,260...49,915,168
Ensembl chr 3:49,753,262...49,915,194
JBrowse link
G Coil coilin affects expression EXP Cocaine affects the expression of COIL mRNA CTD PMID:20187946 NCBI chr10:73,789,077...73,810,378
Ensembl chr10:73,789,488...73,810,393
JBrowse link
G Col15a1 collagen type XV alpha 1 chain affects expression EXP Cocaine affects the expression of COL15A1 mRNA CTD PMID:20187946 NCBI chr 5:61,501,963...61,607,591
Ensembl chr 5:61,501,963...61,607,591
JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression EXP Cocaine results in increased expression of COL1A1 mRNA CTD PMID:9455993 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Col3a1 collagen type III alpha 1 chain increases expression EXP Cocaine results in increased expression of COL3A1 mRNA CTD PMID:9455993 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
JBrowse link
G Coq6 coenzyme Q6 monooxygenase affects expression EXP Cocaine affects the expression of COQ6 mRNA CTD PMID:20187946 NCBI chr 6:104,007,814...104,019,888
Ensembl chr 6:104,007,872...104,024,657
JBrowse link
G Coro7 coronin 7 multiple interactions ISO [Cocaine co-treated with FOS protein mutant form] results in decreased expression of CORO7 mRNA CTD PMID:18355967 NCBI chr10:10,880,299...10,941,001
Ensembl chr10:10,885,196...10,941,001
JBrowse link
G Cox20 cytochrome c oxidase assembly factor COX20 decreases expression EXP Cocaine results in decreased expression of COX20 mRNA CTD PMID:17898221 NCBI chr13:90,065,900...90,075,386 JBrowse link
G Cox5a cytochrome c oxidase subunit 5A affects expression EXP Cocaine affects the expression of COX5A mRNA CTD PMID:20187946 NCBI chr 8:57,922,374...57,933,781
Ensembl chr 8:57,922,290...57,933,781
JBrowse link
G Cox6a1 cytochrome c oxidase subunit 6A1 affects expression
increases expression
EXP Cocaine affects the expression of COX6A1 mRNA
Cocaine results in increased expression of COX6A1 protein
CTD PMID:20187946 PMID:25100957 NCBI chr12:41,261,983...41,265,037
Ensembl chr12:41,261,967...41,265,041
JBrowse link
G Cox6c cytochrome c oxidase subunit 6C decreases expression ISO Cocaine results in decreased expression of COX6C mRNA CTD PMID:12629581 NCBI chr 7:67,129,265...67,142,001
Ensembl chr 7:67,111,024...67,141,963
JBrowse link
G Cox7b cytochrome c oxidase subunit 7B affects expression EXP Cocaine affects the expression of COX7B mRNA CTD PMID:20187946 NCBI chr  X:71,083,486...71,089,733
Ensembl chr  X:71,083,456...71,089,732
JBrowse link
G Cox8a cytochrome c oxidase subunit 8A affects expression EXP Cocaine affects the expression of COX8A mRNA CTD PMID:20187946 NCBI chr 1:204,402,118...204,404,439 JBrowse link
G Cplx1 complexin 1 affects expression EXP Cocaine affects the expression of CPLX1 mRNA CTD PMID:20187946 NCBI chr14:1,184,638...1,216,392 JBrowse link
G Cpne8 copine 8 increases expression EXP Cocaine results in increased expression of CPNE8 mRNA CTD PMID:17898221 NCBI chr 7:121,615,293...121,789,507
Ensembl chr 7:121,615,294...121,790,377
JBrowse link
G Creb1 cAMP responsive element binding protein 1 affects expression
increases phosphorylation
multiple interactions
affects phosphorylation
increases expression
EXP
ISO
Cocaine affects the expression of CREB1 mRNA
Cocaine results in increased phosphorylation of CREB1 protein
CDK5R1 protein inhibits the reaction [Cocaine results in increased phosphorylation of CREB1 protein]; Cocaine inhibits the reaction [CREB1 protein binds to BDNF promoter]; N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine inhibits the reaction [Cocaine results in increased expression of CREB1 protein]; RPS6KA3 gene mutant form inhibits the reaction [Cocaine results in increased phosphorylation of CREB1 protein]; SL 327 inhibits the reaction [Cocaine results in increased phosphorylation of CREB1 protein]
Cocaine affects the phosphorylation of CREB1 protein
Betaxolol affects the reaction [Cocaine affects the phosphorylation of CREB1 protein]; Cocaine affects the reaction [CREB1 modified form binds to BDNF promoter]; Cocaine promotes the reaction [RPS6KA1 protein binds to CREB1 protein]; Cocaine results in increased phosphorylation of and results in increased activity of CREB1 protein; U 0126 inhibits the reaction [Cocaine results in increased phosphorylation of CREB1 protein]
CTD PMID:12595601 PMID:15470197 PMID:15665076 PMID:16219028 PMID:16339038 More... NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Crebbp CREB binding protein increases expression EXP Cocaine results in increased expression of CREBBP mRNA CTD PMID:17898221 NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888
JBrowse link
G Crebrf CREB3 regulatory factor increases expression EXP Cocaine results in increased expression of CREBRF mRNA CTD PMID:17898221 NCBI chr10:16,399,170...16,479,650
Ensembl chr10:16,404,596...16,461,999
JBrowse link
G Crem cAMP responsive element modulator affects expression
increases expression
ISO
EXP
Cocaine affects the expression of CREM mRNA
Cocaine results in increased expression of CREM mRNA
CTD PMID:18355967 PMID:27899881 NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989
JBrowse link
G Crh corticotropin releasing hormone multiple interactions
affects expression
EXP Betaxolol affects the reaction [Cocaine affects the expression of CRH mRNA]; Cocaine affects the reaction [CRH protein affects the secretion of Excitatory Amino Acid Agents]; SCH 23390 affects the reaction [Cocaine affects the expression of CRH mRNA]
Cocaine affects the expression of CRH mRNA; Cocaine affects the expression of CRH protein
CTD PMID:7796157 PMID:11597771 PMID:12782395 PMID:15930388 PMID:18596687 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919
JBrowse link
G Crhbp corticotropin releasing hormone binding protein increases expression EXP Cocaine results in increased expression of CRHBP mRNA CTD PMID:27899881 NCBI chr 2:26,692,403...26,704,710
Ensembl chr 2:26,692,403...26,704,710
JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 increases expression EXP Cocaine results in increased expression of CRHR1 protein CTD PMID:17079348 NCBI chr10:89,040,203...89,083,481
Ensembl chr10:89,040,203...89,083,481
JBrowse link
G Crip2 cysteine-rich protein 2 affects expression EXP Cocaine affects the expression of CRIP2 mRNA CTD PMID:20187946 NCBI chr 6:132,221,120...132,226,066
Ensembl chr 6:132,221,082...132,226,065
JBrowse link
G Crispld1 cysteine-rich secretory protein LCCL domain containing 1 decreases expression EXP Cocaine results in decreased expression of CRISPLD1 mRNA CTD PMID:27899881 NCBI chr 5:1,267,347...1,314,926
Ensembl chr 5:1,274,647...1,314,926
JBrowse link
G Crp C-reactive protein increases expression ISO Cocaine results in increased expression of CRP protein CTD PMID:11988210 NCBI chr13:85,131,635...85,175,179
Ensembl chr13:85,124,977...85,175,178
JBrowse link
G Crtac1 cartilage acidic protein 1 affects expression EXP Cocaine affects the expression of CRTAC1 mRNA CTD PMID:20187946 NCBI chr 1:241,091,679...241,233,677
Ensembl chr 1:241,078,864...241,233,421
JBrowse link
G Crtc1 CREB regulated transcription coactivator 1 multiple interactions EXP [[Cocaine results in increased expression of MIR212 mRNA] which results in increased activity of RAF1 protein] which results in increased expression of CRTC1 protein CTD PMID:20613834 NCBI chr16:18,988,197...19,046,913
Ensembl chr16:18,988,250...19,043,381
JBrowse link
G Cry1 cryptochrome circadian regulator 1 decreases expression ISO Cocaine results in decreased expression of CRY1 mRNA CTD PMID:15994025 NCBI chr 7:18,529,823...18,594,092
Ensembl chr 7:18,529,823...18,594,091
JBrowse link
G Cry2 cryptochrome circadian regulator 2 decreases expression ISO Cocaine results in decreased expression of CRY2 mRNA CTD PMID:15994025 NCBI chr 3:78,374,995...78,405,001
Ensembl chr 3:78,374,995...78,404,965
JBrowse link
G Cryab crystallin, alpha B decreases expression
increases expression
ISO
EXP
Cocaine results in decreased expression of CRYAB mRNA
Cocaine results in increased expression of CRYAB mRNA
CTD PMID:15009677 PMID:27899881 NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157
JBrowse link
G Crybb2 crystallin, beta B2 decreases expression ISO Cocaine results in decreased expression of CRYBB2 mRNA CTD PMID:15009677 NCBI chr12:43,569,747...43,579,671
Ensembl chr12:43,569,747...43,579,671
JBrowse link
G Csad cysteine sulfinic acid decarboxylase affects expression
decreases expression
EXP Cocaine affects the expression of CSAD mRNA
Cocaine results in decreased expression of CSAD protein
CTD PMID:20187946 PMID:25100957 NCBI chr 7:133,308,571...133,337,914
Ensembl chr 7:133,308,574...133,337,615
JBrowse link
G Csf2ra colony stimulating factor 2 receptor subunit alpha decreases expression EXP Cocaine results in decreased expression of CSF2RA mRNA CTD PMID:17898221 NCBI chr14:98,089...103,261
Ensembl chr14:89,172...103,128
JBrowse link
G Csn3 casein kappa affects expression EXP Cocaine affects the expression of CSN3 mRNA CTD PMID:20187946 NCBI chr14:20,154,032...20,160,585
Ensembl chr14:20,154,032...20,160,587
JBrowse link
G Csnk2a1 casein kinase 2 alpha 1 decreases expression EXP Cocaine results in decreased expression of CSNK2A1 mRNA CTD PMID:12117546 NCBI chr 3:140,709,984...140,756,757
Ensembl chr 3:140,709,991...140,756,696
JBrowse link
G Cspg5 chondroitin sulfate proteoglycan 5 affects expression EXP Cocaine affects the expression of CSPG5 mRNA; Cocaine affects the expression of CSPG5 protein CTD PMID:12358776 NCBI chr 8:110,220,653...110,234,750
Ensembl chr 8:110,220,653...110,234,758
JBrowse link
G Csrp2 cysteine and glycine-rich protein 2 decreases expression ISO Cocaine results in decreased expression of CSRP2 mRNA CTD PMID:18000554 NCBI chr 7:46,349,109...46,367,743
Ensembl chr 7:46,348,686...46,367,745
JBrowse link
G Ctdnep1 CTD nuclear envelope phosphatase 1 affects expression EXP Cocaine affects the expression of CTDNEP1 mRNA CTD PMID:20187946 NCBI chr10:54,704,367...54,713,781
Ensembl chr10:54,704,148...54,713,781
JBrowse link
G Ctnnb1 catenin beta 1 affects expression
multiple interactions
EXP Cocaine affects the expression of CTNNB1 mRNA
Cocaine deficiency promotes the reaction [SMARCA4 protein binds to CTNNB1 promoter]
CTD PMID:20187946 PMID:27422367 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Ctnnbip1 catenin, beta-interacting protein 1 decreases expression ISO Cocaine results in decreased expression of CTNNBIP1 mRNA CTD PMID:18000554 NCBI chr 5:159,961,961...160,010,942
Ensembl chr 5:159,961,928...160,010,939
JBrowse link
G Ctnnd2 catenin delta 2 decreases expression
increases expression
ISO
EXP
Cocaine results in decreased expression of CTNND2 mRNA
Cocaine results in increased expression of CTNND2 mRNA
CTD PMID:12629581 PMID:16076954 NCBI chr 2:81,168,976...82,016,495
Ensembl chr 2:81,167,117...82,015,764
JBrowse link
G Ctrl chymotrypsin-like affects expression
increases expression
EXP Cocaine affects the expression of CTRL mRNA
Cocaine results in increased expression of CTRL mRNA
CTD PMID:20187946 PMID:27899881 NCBI chr19:33,827,279...33,829,129
Ensembl chr19:33,827,229...33,833,626
JBrowse link
G Ctsb cathepsin B affects expression
multiple interactions
increases expression
ISO Cocaine affects the expression of CTSB mRNA
FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of CTSB mRNA]
CTD PMID:15681117 PMID:18355967 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
JBrowse link
G Ctsd cathepsin D affects expression
increases expression
ISO
EXP
Cocaine affects the expression of CTSD mRNA
Cocaine results in increased expression of CTSD protein
CTD PMID:15681117 PMID:25100957 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Cuedc1 CUE domain containing 1 multiple interactions ISO HDAC5 affects the reaction [Cocaine affects the expression of CUEDC1 mRNA] CTD PMID:17988634 NCBI chr10:72,892,637...72,986,546
Ensembl chr10:72,892,637...72,986,542
JBrowse link
G Cul4b cullin 4B increases expression ISO Cocaine results in increased expression of CUL4B mRNA CTD PMID:15009677 NCBI chr  X:117,287,481...117,326,688
Ensembl chr  X:117,287,484...117,326,688
JBrowse link
G Cwf19l2 CWF19 like cell cycle control factor 2 increases expression EXP Cocaine results in increased expression of CWF19L2 mRNA CTD PMID:17898221 NCBI chr 6:290,148...356,636
Ensembl chr 6:281,685...356,604
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 increases expression EXP Cocaine results in increased expression of CX3CL1 mRNA CTD PMID:16076954 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases secretion ISO Cocaine results in increased secretion of CXCL10 protein CTD PMID:10065903 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 decreases expression EXP Cocaine results in decreased expression of CXCL9 mRNA CTD PMID:17898221 NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 increases expression ISO Cocaine results in increased expression of CXCR4 protein CTD PMID:16204638 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
JBrowse link
G Cxxc5 CXXC finger protein 5 affects expression EXP Cocaine affects the expression of CXXC5 mRNA CTD PMID:20187946 NCBI chr18:27,427,591...27,458,579
Ensembl chr18:27,427,230...27,458,673
JBrowse link
G Cyba cytochrome b-245 alpha chain increases expression ISO Cocaine results in increased expression of CYBA protein CTD PMID:18952886 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
JBrowse link
G Cybb cytochrome b-245 beta chain increases expression
increases response to substance
ISO Cocaine results in increased expression of CYBB protein
CYBB results in increased susceptibility to Cocaine
CTD PMID:18952886 NCBI chr  X:13,360,583...13,392,517
Ensembl chr  X:13,359,430...13,392,586
JBrowse link
G Cyc1 cytochrome c-1 decreases expression ISO Cocaine results in decreased expression of CYC1 mRNA CTD PMID:12629581 NCBI chr 7:108,067,106...108,069,483
Ensembl chr 7:108,067,115...108,069,479
JBrowse link
G Cycs cytochrome c, somatic multiple interactions
affects expression
EXP
ISO
Minocycline inhibits the reaction [Cocaine results in increased secretion of CYCS protein]
Cocaine affects the expression of CYCS mRNA
CTD PMID:15681117 PMID:21424555 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
JBrowse link
G Cygb cytoglobin decreases expression EXP Cocaine results in decreased expression of CYGB protein CTD PMID:25100957 NCBI chr10:101,877,675...101,887,442
Ensembl chr10:101,877,676...101,887,442
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases expression EXP Cocaine results in decreased expression of CYP19A1 mRNA CTD PMID:27899881 NCBI chr 8:54,553,165...54,580,758
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
ISO Cimetidine inhibits the reaction [Cocaine results in increased expression of CYP1A1 protein]; Metyrapone inhibits the reaction [Cocaine results in increased expression of CYP1A1 protein] CTD PMID:11856816 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 affects expression EXP Cocaine affects the expression of CYP26A1 mRNA CTD PMID:20187946 NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204
JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 decreases response to substance EXP CYP26B1 protein results in decreased susceptibility to Cocaine CTD PMID:27899881 NCBI chr 4:117,041,808...117,058,628
Ensembl chr 4:117,041,808...117,058,628
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 decreases expression ISO Cocaine results in decreased expression of CYP2C8 mRNA; Cocaine results in decreased expression of CYP2C8 protein CTD PMID:16188404
G Cyp2j10 cytochrome P450, family 2, subfamily j, polypeptide 10 decreases expression EXP Cocaine results in decreased expression of CYP2J10 mRNA CTD PMID:27899881 NCBI chr 5:110,960,319...110,995,220
Ensembl chr 5:110,960,317...110,995,115
JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 increases expression
multiple interactions
ISO Cocaine results in increased expression of CYP2J2 protein
Cimetidine inhibits the reaction [Cocaine results in increased expression of CYP2J2 protein]; Metyrapone inhibits the reaction [Cocaine results in increased expression of CYP2J2 protein]
CTD PMID:11856816 NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 affects expression EXP Cocaine affects the expression of CYP3A23-3A1 mRNA CTD PMID:20187946 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
JBrowse link
G Cyp51 cytochrome P450, family 51 decreases expression ISO Cocaine results in decreased expression of CYP51 mRNA CTD PMID:12629581 NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410
JBrowse link
G Cyss cystatin S affects expression EXP Cocaine affects the expression of CYSS mRNA CTD PMID:20187946 NCBI chr 3:137,432,272...137,436,610
Ensembl chr 3:137,432,049...137,436,610
JBrowse link
G Dab2ip DAB2 interacting protein decreases expression EXP Cocaine results in decreased expression of DAB2IP mRNA CTD PMID:17898221 NCBI chr 3:18,915,290...19,086,282
Ensembl chr 3:18,915,290...19,086,280
JBrowse link
G Dazap1 DAZ associated protein 1 affects expression EXP Cocaine affects the expression of DAZAP1 mRNA CTD PMID:20187946 NCBI chr 7:9,423,673...9,448,116
Ensembl chr 7:9,424,178...9,538,818
JBrowse link
G Dbh dopamine beta-hydroxylase increases response to substance
decreases response to substance
ISO DBH gene polymorphism results in increased susceptibility to Cocaine
DBH gene mutant form results in decreased susceptibility to Cocaine
CTD PMID:10673769 PMID:12555232 PMID:18083142 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248
JBrowse link
G Dbn1 drebrin 1 multiple interactions EXP Cocaine deficiency promotes the reaction [SMARCA4 protein binds to DBN1 promoter] CTD PMID:27422367 NCBI chr17:9,150,608...9,164,982
Ensembl chr17:9,150,659...9,164,984
JBrowse link
G Dcaf8 DDB1 and CUL4 associated factor 8 affects expression EXP Cocaine affects the expression of DCAF8 mRNA CTD PMID:20187946 NCBI chr13:84,609,838...84,667,025
Ensembl chr13:84,610,248...84,669,726
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 affects expression
increases expression
ISO
EXP
Cocaine affects the expression of DDIT3 mRNA
Cocaine results in increased expression of DDIT3 mRNA
CTD PMID:15681117 PMID:20187946 PMID:23644055 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 decreases expression EXP Cocaine results in decreased expression of DDR2 mRNA CTD PMID:17898221 NCBI chr13:82,193,623...82,318,229
Ensembl chr13:82,195,463...82,317,363
JBrowse link
G Ddx41 DEAD-box helicase 41 decreases expression ISO Cocaine results in decreased expression of DDX41 mRNA CTD PMID:18000554 NCBI chr17:9,102,926...9,108,415
Ensembl chr17:9,103,010...9,108,415
JBrowse link
G Ddx50 DExD-box helicase 50 affects expression EXP Cocaine affects the expression of DDX50 mRNA CTD PMID:20187946 NCBI chr20:30,561,623...30,591,324
Ensembl chr20:30,560,544...30,591,152
JBrowse link
G Ddx6 DEAD-box helicase 6 increases expression EXP Cocaine results in increased expression of DDX6 mRNA CTD PMID:17898221 NCBI chr 8:44,931,127...44,967,773
Ensembl chr 8:44,931,974...44,964,405
JBrowse link
G Deaf1 DEAF1 transcription factor decreases expression ISO Cocaine results in decreased expression of DEAF1 mRNA CTD PMID:15009677 PMID:16710320 NCBI chr 1:196,401,857...196,435,541
Ensembl chr 1:196,401,857...196,435,541
JBrowse link
G Dhh desert hedgehog signaling molecule affects expression EXP Cocaine affects the expression of DHH mRNA CTD PMID:20187946 NCBI chr 7:130,050,910...130,056,406
Ensembl chr 7:130,050,910...130,056,406
JBrowse link
G Dhx30 DExH-box helicase 30 affects expression EXP Cocaine affects the expression of DHX30 mRNA CTD PMID:20187946 NCBI chr 8:110,064,751...110,096,954
Ensembl chr 8:110,064,752...110,097,381
JBrowse link
G Dipk1b divergent protein kinase domain 1B affects expression EXP Cocaine affects the expression of DIPK1B mRNA CTD PMID:20187946 NCBI chr 3:9,455,914...9,464,169
Ensembl chr 3:9,456,409...9,464,161
JBrowse link
G Dlg2 discs large MAGUK scaffold protein 2 increases expression EXP Cocaine results in increased expression of DLG2 protein CTD PMID:25100957 NCBI chr 1:144,451,653...146,503,949
Ensembl chr 1:144,451,472...146,499,475
JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 affects expression
increases expression
multiple interactions
decreases response to substance
decreases expression
EXP
ISO
Cocaine affects the expression of DLG4 mRNA; Cocaine affects the expression of DLG4 protein
Cocaine results in increased expression of DLG4 protein
ILK mutant form inhibits the reaction [Cocaine results in increased expression of DLG4 protein]
DLG4 protein results in decreased susceptibility to Cocaine
Cocaine results in decreased expression of DLG4 mRNA
CTD PMID:14980210 PMID:19629758 PMID:20187946 PMID:20534846 PMID:20600170 NCBI chr10:54,740,700...54,769,097
Ensembl chr10:54,739,470...54,767,153
JBrowse link
G Dlk2 delta like non-canonical Notch ligand 2 decreases expression
multiple interactions
ISO Cocaine results in decreased expression of DLK2 mRNA
FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of DLK2 mRNA]
CTD PMID:18355967 NCBI chr 9:14,677,102...14,681,515
Ensembl chr 9:14,676,562...14,681,594
JBrowse link
G Dnah8 dynein, axonemal, heavy chain 8 affects response to substance ISO DNAH8 gene SNP affects the susceptibility to Cocaine CTD PMID:18438686 NCBI chr20:8,692,939...8,946,780
Ensembl chr20:8,692,963...8,946,772
JBrowse link
G Dnm1 dynamin 1 affects expression EXP Cocaine affects the expression of DNM1 mRNA CTD PMID:20187946 NCBI chr 3:15,604,782...15,648,654
Ensembl chr 3:15,604,784...15,648,538
JBrowse link
G Dnm1l dynamin 1-like multiple interactions
increases phosphorylation
EXP
ISO
[Cocaine co-treated with Cocaine deficiency] promotes the reaction [RUNX2 protein binds to DNM1L promoter]
Cocaine results in increased phosphorylation of DNM1L protein
CTD PMID:30158054 PMID:31494168 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
JBrowse link
G Dnm2 dynamin 2 affects expression EXP Cocaine affects the expression of DNM2 mRNA CTD PMID:20187946 NCBI chr 8:19,978,313...20,060,162
Ensembl chr 8:19,978,400...20,060,157
JBrowse link
G Dnm3 dynamin 3 affects expression EXP Cocaine affects the expression of DNM3 mRNA CTD PMID:20187946 NCBI chr13:74,359,043...74,838,135
Ensembl chr13:74,359,213...74,838,108
JBrowse link
G Dnmbp dynamin binding protein decreases expression EXP Cocaine results in decreased expression of DNMBP mRNA CTD PMID:17898221 NCBI chr 1:242,736,189...242,829,498
Ensembl chr 1:242,736,189...242,802,604
JBrowse link
G Dnmt3b DNA methyltransferase 3 beta decreases expression
multiple interactions
ISO Cocaine results in decreased expression of DNMT3B mRNA; Cocaine results in decreased expression of DNMT3B protein
Methionine inhibits the reaction [Cocaine results in decreased expression of DNMT3B mRNA]; Methionine inhibits the reaction [Cocaine results in decreased expression of DNMT3B protein]
CTD PMID:22438930 NCBI chr 3:142,130,592...142,169,124
Ensembl chr 3:142,130,592...142,169,124
JBrowse link
G Dnph1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 decreases expression ISO Cocaine results in decreased expression of DNPH1 mRNA CTD PMID:15009677 PMID:16710320 NCBI chr 9:14,481,296...14,484,034
Ensembl chr 9:14,481,066...14,484,022
JBrowse link
G Dpf2 double PHD fingers 2 increases expression ISO Cocaine results in increased expression of DPF2 mRNA CTD PMID:18000554 NCBI chr 1:203,183,674...203,199,037
Ensembl chr 1:203,183,686...203,198,983
JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 multiple interactions EXP [Cocaine affects the activity of PRKACA protein] which affects the phosphorylation of DPYSL2 protein CTD PMID:19457111 NCBI chr15:41,005,551...41,111,724
Ensembl chr15:41,005,551...41,111,829
JBrowse link
G Dpysl3 dihydropyrimidinase-like 3 affects expression EXP Cocaine affects the expression of DPYSL3 mRNA CTD PMID:20187946 NCBI chr18:35,374,429...35,480,462
Ensembl chr18:35,377,181...35,480,157
JBrowse link
G Drd1 dopamine receptor D1 multiple interactions
increases expression
decreases expression
affects response to substance
affects expression
increases response to substance
decreases response to substance
ISO
EXP
1-propyl-5-(3-p-tolylisoxazol-5-yl)-1,2,3,6-tetrahydropyridine inhibits the reaction [Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein]]; 1-propyl-5-(3-p-tolylisoxazol-5-yl)-1,2,3,6-tetrahydropyridine inhibits the reaction [Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein]]; [Cocaine binds to SIGMAR1 protein] affects the folding of [SIGMAR1 protein binds to DRD1 protein]; Cocaine affects the localization of [DRD1 protein binds to SIGMAR1 protein]; Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Cocaine promotes the reaction [DRD1 protein binds to SIGMAR1 protein]; SCH 23390 inhibits the reaction [Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein]]; SCH 23390 inhibits the reaction [Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein]]
Cocaine deficiency results in increased expression of DRD1 mRNA
Cocaine results in decreased expression of DRD1 protein
DRD1 protein affects the susceptibility to Cocaine
Cocaine affects the expression of DRD1 protein
DRD1 results in increased susceptibility to Cocaine
DRD1 gene mutant form results in decreased susceptibility to Cocaine
Cocaine promotes the reaction [DRD1 protein results in increased expression of FOS protein]; Cocaine promotes the reaction [DRD1 protein results in increased expression of NEO1 protein]; Cocaine promotes the reaction [DRD1 protein results in increased expression of PDYN protein]; Cocaine promotes the reaction [DRD1 protein results in increased expression of SYT7 protein]; Cocaine promotes the reaction [DRD1 protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Cocaine promotes the reaction [DRD1 protein results in increased phosphorylation of and results in increased activity of MAPK3 protein]; DRD1 mutant form inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein]; DRD1 mutant form inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein]
[anhydroecgonine methyl ester co-treated with Cocaine] results in decreased expression of DRD1 protein; [SCH 23390 binds to and results in decreased activity of DRD1 protein] inhibits the reaction [Cocaine results in increased expression of FOS protein]; Cocaine affects the reaction [SCH 23390 binds to DRD1 protein]; DRD1 protein affects the reaction [Cocaine results in increased expression of FOSB protein alternative form]; DRD1 protein affects the reaction [Cocaine results in increased expression of FOSB protein]
CTD PMID:2213551 PMID:8001143 PMID:11421588 PMID:11602327 PMID:15049517 More... NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002
JBrowse link
G Drd2 dopamine receptor D2 decreases expression
increases expression
affects response to substance
increases activity
multiple interactions
affects expression
decreases response to substance
increases response to substance
ISO
EXP
Cocaine results in decreased expression of DRD2 mRNA; Cocaine results in decreased expression of DRD2 protein
Cocaine deficiency results in increased expression of DRD2 mRNA
DRD2 protein affects the susceptibility to Cocaine
Cocaine results in increased activity of DRD2 protein
Cocaine results in increased expression of DRD2 mRNA; Cocaine results in increased expression of DRD2 protein
Cocaine affects the reaction [Spiperone binds to DRD2 protein]; Cocaine promotes the reaction [[DRD2 protein results in increased phosphorylation of TH protein] which results in increased abundance of Dopamine]; Methadone affects the reaction [Cocaine affects the expression of DRD2 mRNA]; Spiperone inhibits the reaction [Cocaine promotes the reaction [[DRD2 protein results in increased phosphorylation of TH protein] which results in increased abundance of Dopamine]]
Cocaine affects the expression of DRD2; Cocaine affects the expression of DRD2 mRNA; Cocaine affects the expression of DRD2 protein
DRD2 protein results in decreased susceptibility to Cocaine
PDYN protein affects the reaction [Cocaine affects the expression of DRD2 protein]
DRD2 results in increased susceptibility to Cocaine
DRD2 polymorphism results in increased susceptibility to Cocaine
Cocaine affects the reaction [Raclopride binds to DRD2]
CTD PMID:2213551 PMID:9892293 PMID:11126397 PMID:11602327 PMID:11790512 More... NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Drd3 dopamine receptor D3 decreases expression
decreases response to substance
increases expression
increases activity
affects expression
affects activity
multiple interactions
affects response to substance
ISO
EXP
Cocaine results in decreased expression of DRD3 protein
DRD3 results in decreased susceptibility to Cocaine
Cocaine results in increased expression of DRD3 mRNA
Cocaine results in increased activity of DRD3 protein
Cocaine affects the expression of DRD3 protein
Cocaine affects the activity of DRD3 protein
DRD3 protein results in decreased susceptibility to Cocaine
7-hydroxy-2-N,N-dipropylaminotetralin inhibits the reaction [Cocaine affects the activity of DRD3 protein]; Cocaine promotes the reaction [DRD3 protein binds to CAMK2A protein]; KN 93 inhibits the reaction [Cocaine promotes the reaction [DRD3 protein binds to CAMK2A protein]]
DRD3 affects the susceptibility to Cocaine
[3,4,4a,10b-tetrahydro-4-propyl-2H,5H-(1)benzopyrano(4,3-b)-1,4-oxazin-9-ol binds to and results in increased activity of DRD3 protein] which results in decreased susceptibility to Cocaine; [3,4,4a,10b-tetrahydro-4-propyl-2H,5H-(1)benzopyrano(4,3-b)-1,4-oxazin-9-ol co-treated with Cocaine] affects the localization of DRD3 protein; Cocaine promotes the reaction [DRD3 protein results in decreased expression of FOS protein]; Cocaine promotes the reaction [DRD3 protein results in decreased expression of NEO1 protein]; Cocaine promotes the reaction [DRD3 protein results in decreased expression of PDYN protein]; Cocaine promotes the reaction [DRD3 protein results in decreased expression of SYT7 protein]; Cocaine promotes the reaction [DRD3 protein results in decreased phosphorylation of and results in decreased activity of MAPK1 protein]; Cocaine promotes the reaction [DRD3 protein results in decreased phosphorylation of and results in decreased activity of MAPK3 protein]; DRD3 protein affects the reaction [Cocaine results in increased expression of NTS mRNA]; DRD3 protein inhibits the reaction [Cocaine results in increased expression of FOS protein]; DRD3 protein inhibits the reaction [Cocaine results in increased expression of PDYN protein]; SB 277011 inhibits the reaction [[3,4,4a,10b-tetrahydro-4-propyl-2H,5H-(1)benzopyrano(4,3-b)-1,4-oxazin-9-ol binds to and results in increased activity of DRD3 protein] which results in decreased susceptibility to Cocaine]
CTD PMID:10523822 PMID:10943692 PMID:11120399 PMID:12099907 PMID:15056714 More... NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596
JBrowse link
G Drd4 dopamine receptor D4 increases response to substance
affects expression
ISO
EXP
DRD4 polymorphism results in increased susceptibility to Cocaine
Cocaine affects the expression of DRD4 mRNA
CTD PMID:17671965 PMID:20187946 NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553
JBrowse link
G Drd5 dopamine receptor D5 affects expression EXP Cocaine affects the expression of DRD5 mRNA CTD PMID:20187946 NCBI chr14:72,489,347...72,490,774
Ensembl chr14:72,489,347...72,490,774
JBrowse link
G Drp2 dystrophin related protein 2 affects expression ISO Cocaine affects the expression of DRP2 protein CTD PMID:19393250 NCBI chr  X:97,607,577...97,658,115
Ensembl chr  X:97,607,719...97,655,684
JBrowse link
G Dsp desmoplakin increases expression ISO Cocaine results in increased expression of DSP protein CTD PMID:17075605 NCBI chr17:26,623,602...26,671,692
Ensembl chr17:26,623,588...26,671,800
JBrowse link
G Dusp1 dual specificity phosphatase 1 affects expression
increases phosphorylation
EXP Cocaine affects the expression of DUSP1 mRNA
Cocaine results in increased phosphorylation of DUSP1 protein
CTD PMID:18822274 PMID:20187946 NCBI chr10:16,680,489...16,683,276 JBrowse link
G Dusp5 dual specificity phosphatase 5 affects expression
increases expression
EXP Cocaine affects the expression of CPG21 mRNA
Cocaine results in increased expression of DUSP5 mRNA
CTD PMID:20187946 PMID:27899881 NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818
JBrowse link
G Dusp8 dual specificity phosphatase 8 multiple interactions
increases expression
EXP 5,7-Dihydroxytryptamine inhibits the reaction [Cocaine results in increased expression of DUSP8 mRNA] CTD PMID:9813294 NCBI chr 1:197,167,392...197,184,285
Ensembl chr 1:197,169,422...197,182,921
JBrowse link
G Dvl1 dishevelled segment polarity protein 1 affects expression EXP Cocaine affects the expression of DVL1 mRNA CTD PMID:20187946 NCBI chr 5:166,456,989...166,468,733
Ensembl chr 5:166,456,686...166,468,664
JBrowse link
G Dync1i1 dynein cytoplasmic 1 intermediate chain 1 decreases expression ISO Cocaine results in decreased expression of DYNC1I1 mRNA CTD PMID:12629581 NCBI chr 4:33,852,597...34,166,159
Ensembl chr 4:33,852,927...34,166,149
JBrowse link
G Dync1li2 dynein, cytoplasmic 1 light intermediate chain 2 increases expression EXP Cocaine results in increased expression of DYNC1LI2 protein CTD PMID:25100957 NCBI chr19:531,783...554,670
Ensembl chr19:531,812...554,670
JBrowse link
G Dynll1 dynein light chain LC8-type 1 affects expression EXP Cocaine affects the expression of DYNLL1 mRNA CTD PMID:20187946 NCBI chr12:41,312,367...41,314,742
Ensembl chr12:41,312,367...41,314,741
JBrowse link
G Eci2 enoyl-CoA delta isomerase 2 affects expression EXP Cocaine affects the expression of PECI mRNA CTD PMID:20187946 NCBI chr17:29,850,884...29,886,781
Ensembl chr17:29,870,391...29,886,781
JBrowse link
G Edn1 endothelin 1 increases expression EXP
ISO
Cocaine results in increased expression of EDN1 protein CTD PMID:9714087 PMID:11948058 PMID:17420087 PMID:18813882 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Ednra endothelin receptor type A increases expression ISO
EXP
Cocaine results in increased expression of EDNRA protein CTD PMID:17420087 PMID:18813882 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049
JBrowse link
G Ednrb endothelin receptor type B affects expression EXP Cocaine affects the expression of EDNRB mRNA CTD PMID:20187946 NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115
JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 affects expression EXP Cocaine affects the expression of EEF1A1 mRNA CTD PMID:20187946 NCBI chr 8:79,341,554...79,344,784
Ensembl chr 8:79,341,557...79,344,839
JBrowse link
G Eef1a2 eukaryotic translation elongation factor 1 alpha 2 affects expression EXP Cocaine affects the expression of EEF1A2 mRNA CTD PMID:20187946 NCBI chr 3:168,265,893...168,275,071 JBrowse link
G Eef1g eukaryotic translation elongation factor 1 gamma decreases expression ISO Cocaine results in decreased expression of EEF1G mRNA CTD PMID:15009677 NCBI chr 1:205,860,713...205,871,319
Ensembl chr 1:205,860,698...205,872,382
JBrowse link
G Efcab3 EF-hand calcium binding domain 3 affects expression
decreases expression
EXP Cocaine affects the expression of EFCAB3 mRNA
Cocaine results in decreased expression of EFCAB3 mRNA
CTD PMID:17898221 PMID:20187946 NCBI chr10:89,583,526...90,077,260
Ensembl chr10:89,644,522...90,077,259
JBrowse link
G Efna1 ephrin A1 affects expression EXP Cocaine affects the expression of EFNA1 mRNA CTD PMID:15691709 NCBI chr 2:174,681,676...174,690,306
Ensembl chr 2:174,681,682...174,690,866
JBrowse link
G Efna2 ephrin A2 affects expression EXP Cocaine affects the expression of EFNA2 mRNA CTD PMID:15691709 NCBI chr 7:9,515,635...9,528,071
Ensembl chr 7:9,516,429...9,527,061
JBrowse link
G Efna3 ephrin A3 affects expression EXP Cocaine affects the expression of EFNA3 mRNA CTD PMID:15691709 NCBI chr 2:174,729,192...174,738,111
Ensembl chr 2:174,729,764...174,738,736
JBrowse link
G Efna4 ephrin A4 affects expression EXP Cocaine affects the expression of EFNA4 mRNA CTD PMID:15691709 NCBI chr 2:174,748,729...174,752,979
Ensembl chr 2:174,748,724...174,752,979
JBrowse link
G Efna5 ephrin A5 increases expression EXP Cocaine results in increased expression of EFNA5 mRNA CTD PMID:15691709 NCBI chr 9:102,316,753...102,595,480
Ensembl chr 9:102,320,295...102,597,413
JBrowse link
G Efnb1 ephrin B1 increases expression EXP Cocaine results in increased expression of EFNB1 mRNA CTD PMID:15691709 PMID:17898221 NCBI chr  X:64,257,351...64,270,158
Ensembl chr  X:64,257,351...64,270,157
JBrowse link
G Efnb2 ephrin B2 increases expression EXP Cocaine results in increased expression of EFNB2 mRNA CTD PMID:15691709 NCBI chr16:80,783,389...80,827,420
Ensembl chr16:80,783,417...80,824,391
JBrowse link
G Efnb3 ephrin B3 increases expression EXP Cocaine results in increased expression of EFNB3 mRNA CTD PMID:15691709 NCBI chr10:54,274,506...54,281,951
Ensembl chr10:54,274,506...54,280,471
JBrowse link
G Eftud2 elongation factor Tu GTP binding domain containing 2 affects expression EXP Cocaine affects the expression of EFTUD2 mRNA CTD PMID:20187946 NCBI chr10:87,804,893...87,852,181
Ensembl chr10:87,804,892...87,846,079
JBrowse link
G Egfr epidermal growth factor receptor decreases expression ISO Cocaine results in decreased expression of EGFR mRNA CTD PMID:18000554 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Egr1 early growth response 1 affects expression
decreases expression
increases expression
multiple interactions
increases response to substance
ISO
EXP
Cocaine affects the expression of EGR1 mRNA
Cocaine deficiency results in decreased expression of EGR1 mRNA
Cocaine results in increased expression of EGR1 protein
NPPC protein inhibits the reaction [Cocaine results in increased expression of EGR1 mRNA]
Cocaine results in increased expression of EGR1 mRNA; Cocaine results in increased expression of EGR1 protein
EGR1 results in increased susceptibility to Cocaine
[Cocaine co-treated with Caffeine] results in increased expression of EGR1 mRNA; Cocaine promotes the reaction [Caffeine results in increased expression of EGR1 mRNA]
CTD PMID:1347779 PMID:7905595 PMID:9890435 PMID:10971643 PMID:11860464 More... NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Egr2 early growth response 2 increases expression
affects expression
ISO
EXP
Cocaine results in increased expression of EGR2 mRNA
Cocaine affects the expression of EGR2 mRNA
CTD PMID:20056891 PMID:20187946 PMID:27899881 NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562
JBrowse link
G Egr3 early growth response 3 affects expression
decreases expression
multiple interactions
increases expression
EXP
ISO
Cocaine affects the expression of EGR3 mRNA
Cocaine deficiency results in decreased expression of EGR3 mRNA
[Cocaine co-treated with Cocaine deficiency] promotes the reaction [RUNX2 protein binds to EGR3 promoter]
Cocaine results in increased expression of EGR3 mRNA
CTD PMID:16459018 PMID:20187946 PMID:27126842 PMID:30158054 NCBI chr15:45,150,335...45,156,052
Ensembl chr15:45,150,567...45,154,627
JBrowse link
G Egr4 early growth response 4 increases expression EXP Cocaine results in increased expression of EGR4 mRNA CTD PMID:27899881 NCBI chr 4:118,047,869...118,050,328
Ensembl chr 4:118,047,869...118,050,328
JBrowse link
G Ehd2 EH-domain containing 2 decreases expression EXP Cocaine results in decreased expression of EHD2 mRNA CTD PMID:17898221 NCBI chr 1:76,639,568...76,658,747
Ensembl chr 1:76,637,482...76,658,783
JBrowse link
G Ehmt1 euchromatic histone lysine methyltransferase 1 decreases expression ISO Cocaine results in decreased expression of EHMT1 mRNA CTD PMID:20056891 NCBI chr 3:7,580,680...7,729,046
Ensembl chr 3:7,580,683...7,729,007
JBrowse link
G Ehmt2 euchromatic histone lysine methyltransferase 2 multiple interactions
decreases response to substance
decreases expression
ISO Cocaine inhibits the reaction [Cocaine promotes the reaction [EHMT2 protein binds to FOSB protein]]; Cocaine promotes the reaction [EHMT2 protein binds to FOSB protein]; EHMT2 inhibits the reaction [Cocaine results in increased expression of ATM mRNA]; EHMT2 inhibits the reaction [Cocaine results in increased expression of ELMO1 mRNA]; EHMT2 inhibits the reaction [Cocaine results in increased expression of TGFBR1 mRNA]; EHMT2 inhibits the reaction [Cocaine results in increased expression of TNFRSF25 mRNA]; EHMT2 inhibits the reaction [Cocaine results in increased expression of USP9X mRNA]; EHMT2 inhibits the reaction [Cocaine results in increased expression of WNK3 mRNA]; EHMT2 protein inhibits the reaction [Cocaine results in increased expression of FOSB mRNA]
EHMT2 results in decreased susceptibility to Cocaine
Cocaine results in decreased expression of EHMT2 mRNA; Cocaine results in decreased expression of EHMT2 protein
CTD PMID:20056891 NCBI chr20:3,919,623...3,936,751
Ensembl chr20:3,919,624...3,941,547
JBrowse link
G Eif1a eukaryotic translation initiation factor 1A increases expression EXP Cocaine results in increased expression of EIF1A mRNA; Cocaine results in increased expression of EIF1AY mRNA CTD PMID:17898221 NCBI chr18:39,325,695...39,338,043
Ensembl chr18:39,325,202...39,338,696
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 increases expression
multiple interactions
EXP Cocaine results in increased expression of EIF2AK3 protein
6-methyl-2-(phenylethynyl)pyridine inhibits the reaction [Cocaine results in increased expression of EIF2AK3 protein]; Dizocilpine Maleate inhibits the reaction [Cocaine results in increased expression of EIF2AK3 protein]; N-phenyl-7-(hydroxyimino)cyclopropa(b)chromen-1a-carboxamide inhibits the reaction [Cocaine results in increased expression of EIF2AK3 protein]; SCH 23390 inhibits the reaction [Cocaine results in increased expression of EIF2AK3 protein]
CTD PMID:17303341 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation EXP Cocaine results in increased phosphorylation of EIF2S1 CTD PMID:18593214 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225
JBrowse link
G Eif3a eukaryotic translation initiation factor 3, subunit A increases expression EXP Cocaine results in increased expression of EIF3A mRNA CTD PMID:17898221 NCBI chr 1:259,902,767...259,932,976
Ensembl chr 1:259,902,680...259,932,976
JBrowse link
G Eif3b eukaryotic translation initiation factor 3, subunit B affects expression EXP Cocaine affects the expression of EIF3B mRNA CTD PMID:20187946 NCBI chr12:14,196,403...14,220,865
Ensembl chr12:14,196,403...14,220,886
JBrowse link
G Eif3c eukaryotic translation initiation factor 3, subunit C increases expression EXP Cocaine results in increased expression of EIF3C mRNA CTD PMID:17898221 NCBI chr 1:181,134,604...181,152,489
Ensembl chr 1:181,134,604...181,152,493
JBrowse link
G Eif3e eukaryotic translation initiation factor 3 subunit E affects expression EXP Cocaine affects the expression of EIF3E mRNA CTD PMID:20187946 NCBI chr 7:75,257,366...75,265,601 JBrowse link
G Eif4b eukaryotic translation initiation factor 4B multiple interactions
increases expression
ISO FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of EIF4B mRNA] CTD PMID:18355967 NCBI chr 7:133,206,637...133,228,436 JBrowse link
G Eif5a eukaryotic translation initiation factor 5A decreases expression
affects expression
increases expression
ISO
EXP
Cocaine results in decreased expression of EIF5A mRNA
Cocaine affects the expression of EIF5A mRNA
Cocaine results in increased expression of EIF5A mRNA
CTD PMID:15009677 PMID:16710320 PMID:20187946 NCBI chr10:54,640,104...54,644,845
Ensembl chr10:54,640,024...54,644,656
JBrowse link
G Eif5b eukaryotic translation initiation factor 5B increases expression EXP Cocaine results in increased expression of EIF5B mRNA CTD PMID:17898221 NCBI chr 9:40,222,769...40,277,482
Ensembl chr 9:40,222,898...40,277,482
JBrowse link
G Eif5b-ps1 eukaryotic translation initiation factor 5B, pseudogene 1 increases expression EXP Cocaine results in increased expression of EIF5B-PS1 mRNA CTD PMID:17898221 NCBI chr19:35,387,899...35,392,006 JBrowse link
G Elane elastase, neutrophil expressed multiple interactions ISO [Cocaine affects the reaction [Antibodies, Antineutrophil Cytoplasmic binds to ELANE protein]] which results in decreased activity of ELANE protein; Cocaine affects the reaction [Antibodies, Antineutrophil Cytoplasmic binds to ELANE protein] CTD PMID:18438818 NCBI chr 7:9,817,251...9,819,174
Ensembl chr 7:9,817,252...9,819,100
JBrowse link
G Elmo1 engulfment and cell motility 1 multiple interactions
increases expression
ISO EHMT2 inhibits the reaction [Cocaine results in increased expression of ELMO1 mRNA] CTD PMID:20056891 NCBI chr17:44,286,495...44,822,788
Ensembl chr17:44,286,485...44,822,788
JBrowse link
G Emc9 ER membrane protein complex subunit 9 affects expression EXP Cocaine affects the expression of EMC9 mRNA CTD PMID:20187946 NCBI chr15:29,071,881...29,076,098
Ensembl chr15:29,071,883...29,076,098
JBrowse link
G Enah ENAH, actin regulator increases expression EXP Cocaine results in increased expression of ENAH mRNA CTD PMID:17898221 NCBI chr13:93,617,751...93,738,119
Ensembl chr13:93,626,944...93,740,955
JBrowse link
G Enc1 ectodermal-neural cortex 1 increases expression EXP Cocaine results in increased expression of ENC1 mRNA CTD PMID:17898221 NCBI chr 2:28,550,670...28,562,591
Ensembl chr 2:28,550,464...28,562,713
JBrowse link
G Enho energy homeostasis associated decreases expression ISO Cocaine results in decreased expression of ENHO mRNA CTD PMID:16710320 NCBI chr 5:56,800,980...56,802,777
Ensembl chr 5:56,800,980...56,802,777
JBrowse link
G Eno2 enolase 2 decreases expression
increases expression
ISO Cocaine results in decreased expression of ENO2 mRNA
Cocaine results in increased expression of ENO2 protein
CTD PMID:12629581 PMID:17075605 NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980
JBrowse link
G Enpp5 ectonucleotide pyrophosphatase/phosphodiesterase family member 5 increases expression ISO Cocaine results in increased expression of ENPP5 mRNA CTD PMID:15009677 NCBI chr 9:16,910,187...16,917,633
Ensembl chr 9:16,910,831...16,917,480
JBrowse link
G Entpd2 ectonucleoside triphosphate diphosphohydrolase 2 decreases expression EXP Cocaine results in decreased expression of ENTPD2 protein CTD PMID:25100957 NCBI chr 3:8,213,575...8,219,094
Ensembl chr 3:8,213,663...8,226,866
JBrowse link
G Entpd3 ectonucleoside triphosphate diphosphohydrolase 3 multiple interactions ISO [Cocaine co-treated with FOS protein mutant form] results in decreased expression of ENTPD3 mRNA CTD PMID:18355967 NCBI chr 8:120,246,412...120,277,943
Ensembl chr 8:120,247,121...120,277,943
JBrowse link
G Epha1 Eph receptor A1 affects expression EXP Cocaine affects the expression of EPHA1 mRNA CTD PMID:15691709 NCBI chr 4:71,246,409...71,260,920
Ensembl chr 4:71,246,409...71,260,846
JBrowse link
G Epha2 Eph receptor A2 affects expression EXP Cocaine affects the expression of EPHA2 mRNA CTD PMID:15691709 NCBI chr 5:153,605,644...153,634,115
Ensembl chr 5:153,605,644...153,634,117
JBrowse link
G Epha3 Eph receptor A3 affects expression EXP Cocaine affects the expression of EPHA3 mRNA CTD PMID:15691709 NCBI chr11:1,138,485...1,474,102
Ensembl chr11:1,140,985...1,473,900
JBrowse link
G Epha4 Eph receptor A4 affects expression
increases expression
EXP Cocaine affects the expression of EPHA4 mRNA
Cocaine results in increased expression of EPHA4 mRNA
CTD PMID:15691709 PMID:17898221 NCBI chr 9:78,815,460...78,958,139
Ensembl chr 9:78,815,460...78,958,139
JBrowse link
G Epha5 EPH receptor A5 affects expression EXP Cocaine affects the expression of EPHA5 mRNA CTD PMID:15691709 NCBI chr14:23,653,393...24,020,135
Ensembl chr14:23,653,393...24,017,317
JBrowse link
G Epha7 Eph receptor A7 affects expression EXP Cocaine affects the expression of EPHA7 mRNA CTD PMID:15691709 NCBI chr 5:42,975,353...43,128,703
Ensembl chr 5:42,975,405...43,127,112
JBrowse link
G Epha8 Eph receptor A8 affects expression EXP Cocaine affects the expression of EPHA8 mRNA CTD PMID:15691709 NCBI chr 5:149,166,107...149,193,498
Ensembl chr 5:149,166,697...149,193,399
JBrowse link
G Ephb1 Eph receptor B1 increases expression ISO
EXP
Cocaine results in increased expression of EPHB1 protein
Cocaine results in increased expression of EPHB1 mRNA
CTD PMID:11146119 PMID:15691709 NCBI chr 8:102,507,549...102,944,839
Ensembl chr 8:102,507,549...102,944,839
JBrowse link
G Ephb2 Eph receptor B2 increases expression EXP Cocaine results in increased expression of EPHB2 mRNA CTD PMID:15691709 NCBI chr 5:148,889,574...149,077,027
Ensembl chr 5:148,897,246...149,077,059
JBrowse link
G Ephb3 Eph receptor B3 affects expression EXP Cocaine affects the expression of EPHB3 mRNA CTD PMID:15691709 NCBI chr11:79,840,668...79,859,467
Ensembl chr11:79,840,668...79,859,370
JBrowse link
G Ephb4 EPH receptor B4 decreases expression
affects expression
ISO
EXP
Cocaine results in decreased expression of EPHB4 mRNA
Cocaine affects the expression of EPHB4 mRNA
CTD PMID:15691709 PMID:18000554 NCBI chr12:19,326,411...19,351,667
Ensembl chr12:19,326,427...19,351,314
JBrowse link
G Ephb6 Eph receptor B6 affects expression EXP Cocaine affects the expression of EPHB6 mRNA CTD PMID:15691709 NCBI chr 4:70,491,973...70,507,230
Ensembl chr 4:70,491,973...70,507,230
JBrowse link
G Erbin erbb2 interacting protein multiple interactions ISO HDAC5 affects the reaction [Cocaine affects the expression of ERBIN mRNA] CTD PMID:17988634 NCBI chr 2:34,926,962...35,028,440
Ensembl chr 2:34,928,863...35,027,852
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions
increases expression
EXP 6-methyl-2-(phenylethynyl)pyridine inhibits the reaction [Cocaine results in increased expression of ERN1 protein]; Dizocilpine Maleate inhibits the reaction [Cocaine results in increased expression of ERN1 protein]; N-phenyl-7-(hydroxyimino)cyclopropa(b)chromen-1a-carboxamide inhibits the reaction [Cocaine results in increased expression of ERN1 protein]; SCH 23390 inhibits the reaction [Cocaine results in increased expression of ERN1 protein] CTD PMID:17303341 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
JBrowse link
G Ess2 ess-2 splicing factor homolog decreases expression EXP Cocaine results in decreased expression of ESS2 mRNA CTD PMID:17898221 NCBI chr11:83,075,893...83,085,849
Ensembl chr11:83,075,925...83,084,846
JBrowse link
G Etf1 eukaryotic translation termination factor 1 affects expression EXP Cocaine affects the expression of ETF1 mRNA CTD PMID:20187946 NCBI chr18:26,502,413...26,530,753
Ensembl chr18:26,504,080...26,530,810
JBrowse link
G Etfa electron transfer flavoprotein subunit alpha affects expression EXP Cocaine affects the expression of ETFA mRNA CTD PMID:20187946 NCBI chr 8:55,835,115...55,891,890
Ensembl chr 8:55,835,134...55,891,969
JBrowse link
G Exoc2 exocyst complex component 2 increases expression EXP Cocaine results in increased expression of EXOC2 protein CTD PMID:25100957 NCBI chr17:33,506,289...33,698,246
Ensembl chr17:33,506,338...33,693,289
JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 increases expression ISO Cocaine results in increased expression of EYA1 mRNA CTD PMID:15009677 NCBI chr 5:4,863,501...5,101,483
Ensembl chr 5:4,955,543...5,101,483
JBrowse link
G Eya2 EYA transcriptional coactivator and phosphatase 2 affects expression EXP Cocaine affects the expression of EYA2 mRNA CTD PMID:20187946 NCBI chr 3:154,335,558...154,519,006
Ensembl chr 3:154,335,400...154,518,793
JBrowse link
G Ezr ezrin decreases expression ISO Cocaine results in decreased expression of EZR mRNA CTD PMID:20948987 NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505
JBrowse link
G Fadd Fas associated via death domain affects expression
multiple interactions
decreases expression
EXP Cocaine affects the expression of FADD mRNA
Raclopride affects the reaction [Cocaine affects the expression of FADD protein]
Cocaine results in decreased expression of FADD protein modified form
CTD PMID:18580876 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
JBrowse link
G Fahd1 fumarylacetoacetate hydrolase domain containing 1 increases expression EXP Cocaine results in increased expression of FAHD1 protein CTD PMID:25100957 NCBI chr10:13,873,539...13,874,978
Ensembl chr10:13,873,527...13,875,012
JBrowse link
G Faim Fas apoptotic inhibitory molecule affects expression ISO Cocaine affects the expression of FAIM mRNA CTD PMID:15681117 NCBI chr 8:99,543,877...99,569,499
Ensembl chr 8:99,542,405...99,560,562
JBrowse link
G Faim2 Fas apoptotic inhibitory molecule 2 increases expression EXP Cocaine results in increased expression of FAIM2 mRNA CTD PMID:16076954 NCBI chr 7:130,632,368...130,659,353
Ensembl chr 7:130,633,348...130,659,168
JBrowse link
G Fam184b family with sequence similarity 184, member B decreases expression EXP Cocaine results in decreased expression of FAM184B mRNA CTD PMID:27899881 NCBI chr14:65,475,489...65,591,388
Ensembl chr14:65,475,489...65,591,388
JBrowse link
G Fam20c FAM20C, golgi associated secretory pathway kinase affects expression EXP Cocaine affects the expression of FAM20C mRNA CTD PMID:20187946 NCBI chr12:15,826,864...15,885,423
Ensembl chr12:15,826,871...15,884,543
JBrowse link
G Fam78b family with sequence similarity 78, member B decreases expression EXP Cocaine results in decreased expression of FAM78B mRNA CTD PMID:17898221 NCBI chr13:79,162,405...79,250,958 JBrowse link
G Fas Fas cell surface death receptor increases expression ISO Cocaine results in increased expression of FAS mRNA CTD PMID:16710320 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Fbxl3 F-box and leucine-rich repeat protein 3 increases expression EXP Cocaine results in increased expression of FBXL3 mRNA CTD PMID:17898221 NCBI chr15:79,906,795...79,926,678
Ensembl chr15:79,906,795...79,927,867
JBrowse link
G Fbxo46 F-box protein 46 affects expression EXP Cocaine affects the expression of FBXO46 mRNA CTD PMID:20187946 NCBI chr 1:78,770,059...78,786,582
Ensembl chr 1:78,770,018...78,790,097
JBrowse link
G Fcgr2b Fc fragment of IgG receptor IIb decreases expression EXP Cocaine results in decreased expression of FCGR2B mRNA CTD PMID:27899881 NCBI chr13:83,191,253...83,207,776
Ensembl chr13:83,193,163...83,207,778
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 increases expression ISO Cocaine results in increased expression of FDFT1 mRNA CTD PMID:17205118 NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287
JBrowse link
G Fev FEV transcription factor, ETS family member decreases expression EXP Cocaine results in decreased expression of FEV mRNA CTD PMID:17898221 NCBI chr 9:76,439,164...76,443,603
Ensembl chr 9:76,439,172...76,443,065
JBrowse link
G Fgd5 FYVE, RhoGEF and PH domain containing 5 increases expression EXP Cocaine results in increased expression of FGD5 mRNA CTD PMID:17898221 NCBI chr 4:124,497,061...124,594,564
Ensembl chr 4:124,497,068...124,594,563
JBrowse link
G Fgf12 fibroblast growth factor 12 affects expression EXP Cocaine affects the expression of FGF12 mRNA CTD PMID:20187946 NCBI chr11:71,997,049...72,564,965
Ensembl chr11:71,997,099...72,562,607
JBrowse link
G Fgf2 fibroblast growth factor 2 decreases expression ISO Cocaine results in decreased expression of FGF2 mRNA CTD PMID:12629581 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 increases expression EXP Cocaine results in increased expression of FGFR1 mRNA CTD PMID:16076954 NCBI chr16:66,492,445...66,546,731
Ensembl chr16:66,494,042...66,547,350
JBrowse link
G Fh fumarate hydratase affects expression ISO Cocaine affects the expression of FH1 protein CTD PMID:19393250 NCBI chr13:87,524,331...87,550,215
Ensembl chr13:87,524,337...87,550,266
JBrowse link
G Fis1 fission, mitochondrial 1 increases expression ISO Cocaine results in increased expression of FIS1 mRNA CTD PMID:31494168 NCBI chr12:19,708,558...19,723,392
Ensembl chr12:19,708,558...19,723,377
JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B affects expression EXP Cocaine affects the expression of FKBP1B mRNA CTD PMID:20187946 NCBI chr 6:27,832,128...27,850,600
Ensembl chr 6:27,838,802...27,848,653
JBrowse link
G Fkbpl FKBP prolyl isomerase like affects expression EXP Cocaine affects the expression of FKBPL mRNA CTD PMID:20187946 NCBI chr20:4,099,845...4,101,315
Ensembl chr20:4,099,806...4,101,368
JBrowse link
G Flrt3 fibronectin leucine rich transmembrane protein 3 increases expression ISO Cocaine results in increased expression of FLRT3 mRNA CTD PMID:18000554 NCBI chr 3:127,994,491...128,008,137
Ensembl chr 3:127,994,226...128,007,841
JBrowse link
G Flywch1 FLYWCH-type zinc finger 1 decreases expression EXP Cocaine results in decreased expression of FLYWCH1 mRNA CTD PMID:17898221 NCBI chr10:12,774,644...12,794,373
Ensembl chr10:12,774,653...12,794,267
JBrowse link
G Fmr1 FMRP translational regulator 1 decreases expression EXP Cocaine results in decreased expression of FMR1 mRNA CTD PMID:24810662 NCBI chr  X:147,240,239...147,278,057
Ensembl chr  X:147,240,301...147,278,050
JBrowse link
G Fndc1 fibronectin type III domain containing 1 multiple interactions ISO [Cocaine co-treated with FOS protein mutant form] results in decreased expression of FNDC1 mRNA CTD PMID:18355967 NCBI chr 1:47,281,839...47,364,247
Ensembl chr 1:47,281,844...47,364,259
JBrowse link
G Fndc5 fibronectin type III domain containing 5 affects expression EXP Cocaine affects the expression of FNDC5 mRNA CTD PMID:20187946 NCBI chr 5:141,481,593...141,491,257
Ensembl chr 5:141,481,590...141,490,731
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
affects expression
increases phosphorylation
decreases response to substance
increases activity
decreases expression
ISO
EXP
[Cocaine co-treated with SLC6A3 protein] results in increased expression of FOS protein; Cocaine inhibits the reaction [[Dopamine co-treated with SLC6A3 protein] results in increased expression of FOS mRNA]; Cocaine inhibits the reaction [[Dopamine co-treated with SLC6A3 protein] results in increased expression of FOS protein]
Cocaine results in increased expression of FOS mRNA; Cocaine results in increased expression of FOS protein
Cocaine affects the expression of FOS mRNA; Cocaine affects the expression of FOS protein
Cocaine results in increased phosphorylation of FOS protein
[Morphine co-treated with Cocaine] affects the expression of FOS; [SCH 23390 binds to and results in decreased activity of DRD1 protein] inhibits the reaction [Cocaine results in increased expression of FOS protein]; Alcohols promotes the reaction [Cocaine results in increased expression of FOS protein]; Baclofen inhibits the reaction [Cocaine results in increased expression of FOS protein]; Chloral Hydrate inhibits the reaction [Cocaine results in increased expression of FOS protein]; Cocaine promotes the reaction [[SK&F 81297 co-treated with Quinpirole] results in increased expression of FOS protein]; Cocaine promotes the reaction [Cocaine results in increased expression of FOS mRNA]; Cocaine promotes the reaction [Ethanol results in increased expression of FOS protein]; Dizocilpine Maleate inhibits the reaction [Cocaine results in increased expression of FOS protein]; ecopipam inhibits the reaction [Cocaine results in increased expression of FOS protein]; Ethanol promotes the reaction [Cocaine results in increased expression of FOS protein]; Muscimol inhibits the reaction [Cocaine results in increased expression of FOS protein]; NPPC protein inhibits the reaction [Cocaine results in increased expression of FOS mRNA]; Reserpine inhibits the reaction [Cocaine results in increased expression of FOS protein]; SCH 23390 inhibits the reaction [Cocaine results in increased expression of FOS protein]; Urethane inhibits the reaction [Cocaine results in increased expression of FOS protein]; volinanserin inhibits the reaction [Cocaine results in increased expression of FOS protein]
FOS protein mutant form results in decreased susceptibility to Cocaine
Cocaine results in increased activity of FOS protein
Cocaine deficiency results in decreased expression of FOS protein; Cocaine results in decreased expression of FOS protein
[[Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOS protein] which affects the expression of NEO1 protein; [[Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOS protein] which affects the expression of PDYN protein; [[Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOS protein] which affects the expression of SYT7 protein; [Cocaine co-treated with Caffeine] results in increased expression of FOS mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of ATPAF1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of CD4 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of CORO7 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of ENTPD3 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of FNDC1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of ITPR1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of NEXN mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of PBX2 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of PER1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of PINX1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of PKNOX2 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of PLPP1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of PRKCZ mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of SHANK3 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of SYT9 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of THRA mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of ADGRA1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of CAB39L mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of CAMK1G mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of CBLN1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of GRIP1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of INA mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of LARGE1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of NRIP3 mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of SATB2 mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of SORCS3 mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of TENM4 mRNA; [Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOS protein; [Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein] which results in increased expression of FOS protein; Baclofen inhibits the reaction [Cocaine results in increased expression of FOS protein]; CDK5R1 protein inhibits the reaction [Cocaine affects the expression of FOS mRNA]; CDK5R1 protein inhibits the reaction [Cocaine results in increased expression of FOS protein]; CNR1 mutant form inhibits the reaction [Cocaine results in increased expression of FOS protein]; Cocaine promotes the reaction [Caffeine results in increased expression of FOS mRNA]; Cocaine promotes the reaction [DRD1 protein results in increased expression of FOS protein]; Cocaine promotes the reaction [DRD3 protein results in decreased expression of FOS protein]; cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester inhibits the reaction [Cocaine results in increased expression of FOS protein]; DRD3 protein inhibits the reaction [Cocaine results in increased expression of FOS protein]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of BDNF mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of CALR mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of DLK2 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of HOMER2 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of HS3ST2 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of MAPK11 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of NCALD mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of NPTXR mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of NRN1 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of PRKCA mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of SATB1 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of SEZ6L mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of ATP1B3 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of ATP8B2 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of CLK1 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of CTSB mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of EIF4B mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of GPC5 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of KCNT1 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of KDM3A mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of LIN7B mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of LZTS3 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of MEPCE mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of NIT2 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of NOS3 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of PBX3 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of PPP1R7 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of PRPF18 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of PTPRV mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of SBSN mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of SYNE1 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of SYT2 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of TSPOAP1 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of ZFPM1 mRNA]; GPX1 protein inhibits the reaction [Cocaine results in increased expression of FOS protein]; N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine inhibits the reaction [Cocaine results in increased expression of FOS protein]; N-methyl-3-(bis(4'-fluorophenyl)methoxy)tropane inhibits the reaction [Cocaine results in increased expression of FOS protein]; NTRK2 protein affects the reaction [Cocaine affects the expression of FOS protein]; prolinedithiocarbamate inhibits the reaction [Cocaine results in increased expression of FOS protein]; RPS6KA3 affects the reaction [Cocaine results in increased phosphorylation of FOS protein]; SL 327 inhibits the reaction [[Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOS protein]; SL 327 inhibits the reaction [[Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein] which results in increased expression of FOS protein]; SL 327 inhibits the reaction [Cocaine results in increased activity of FOS protein]; SL 327 inhibits the reaction [Cocaine results in increased expression of FOS mRNA]; SL 327 inhibits the reaction [Cocaine results in increased expression of FOS protein]
CTD PMID:1498673 PMID:2118661 PMID:7905595 PMID:10415707 PMID:10521585 More... NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
affects expression
ISO
EXP
Cocaine results in increased expression of FOSB protein
DRD1 protein affects the reaction [Cocaine results in increased expression of FOSB protein alternative form]; DRD1 protein affects the reaction [Cocaine results in increased expression of FOSB protein]; SCH 23390 inhibits the reaction [Cocaine results in increased expression of FOSB protein alternative form]; SCH 23390 inhibits the reaction [Cocaine results in increased expression of FOSB protein]
Cocaine results in increased expression of FOSB mRNA; Cocaine results in increased expression of FOSB protein; Cocaine results in increased expression of FOSB protein alternative form
Cocaine affects the expression of FOSB mRNA; Cocaine affects the expression of FOSB protein
[Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOSB protein; [Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein] which results in increased expression of FOSB protein; [JUND protein results in decreased activity of FOSB protein] which results in decreased susceptibility to Cocaine; Cocaine inhibits the reaction [Cocaine promotes the reaction [EHMT2 protein binds to FOSB protein]]; Cocaine promotes the reaction [EHMT2 protein binds to FOSB protein]; EHMT2 protein inhibits the reaction [Cocaine results in increased expression of FOSB mRNA]; N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine inhibits the reaction [Cocaine results in increased expression of FOSB protein alternative form]; PPP1R1B gene mutant form inhibits the reaction [Cocaine results in increased expression of FOSB protein]; SL 327 inhibits the reaction [[Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOSB protein]; SL 327 inhibits the reaction [[Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein] which results in increased expression of FOSB protein]; SL 327 inhibits the reaction [Cocaine results in increased expression of FOSB protein alternative form]
CTD PMID:10103106 PMID:11391778 PMID:11739600 PMID:12417638 PMID:15056714 More... NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit affects expression
decreases expression
EXP
ISO
Cocaine affects the expression of FOSL1 mRNA
Cocaine results in decreased expression of FOSL1 mRNA
CTD PMID:12117546 PMID:12629581 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit multiple interactions
decreases expression
ISO Cocaine promotes the reaction [JUN protein binds to FOSL2 protein]
[Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOSL2 protein; [Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein] which results in increased expression of FOSL2 protein; SL 327 inhibits the reaction [[Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOSL2 protein]; SL 327 inhibits the reaction [[Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein] which results in increased expression of FOSL2 protein]
Cocaine results in decreased expression of FOSL2 protein
CTD PMID:15056714 PMID:15814102 NCBI chr 6:24,297,898...24,319,157
Ensembl chr 6:24,300,956...24,320,034
JBrowse link
G Foxc2 forkhead box C2 decreases expression EXP Cocaine results in decreased expression of FOXC2 mRNA CTD PMID:17898221 NCBI chr19:49,186,034...49,188,736
Ensembl chr19:49,185,662...49,188,737
JBrowse link
G Foxo1 forkhead box O1 decreases expression EXP Cocaine results in decreased expression of FOXO1 mRNA CTD PMID:17898221 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
JBrowse link
G Foxp1 forkhead box P1 increases expression ISO Cocaine deficiency results in increased expression of FOXP1 mRNA CTD PMID:27126842 NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258
JBrowse link
G Fras1 Fraser extracellular matrix complex subunit 1 increases expression EXP Cocaine results in increased expression of FRAS1 mRNA CTD PMID:17898221 NCBI chr14:12,791,407...13,200,862
Ensembl chr14:12,793,599...13,200,726
JBrowse link
G Frem2 FRAS1 related extracellular matrix 2 decreases expression EXP Cocaine results in decreased expression of FREM2 mRNA CTD PMID:27899881 NCBI chr 2:137,602,784...137,740,785
Ensembl chr 2:137,602,784...137,740,785
JBrowse link
G Frmd5 FERM domain containing 5 decreases expression EXP Cocaine results in decreased expression of FRMD5 mRNA CTD PMID:17898221 NCBI chr 3:108,492,099...108,763,715
Ensembl chr 3:108,474,562...108,763,498
JBrowse link
G Frs3 fibroblast growth factor receptor substrate 3 affects expression EXP Cocaine affects the expression of FRS3 mRNA CTD PMID:20187946 NCBI chr 9:13,288,559...13,297,285
Ensembl chr 9:13,288,667...13,295,382
JBrowse link
G Fubp1 far upstream element binding protein 1 affects expression EXP Cocaine affects the expression of FUBP1 mRNA CTD PMID:20187946 NCBI chr 2:241,159,481...241,186,591
Ensembl chr 2:241,159,512...241,186,602
JBrowse link
G Fut8 fucosyltransferase 8 affects expression EXP Cocaine affects the expression of FUT8 mRNA CTD PMID:20187946 NCBI chr 6:95,948,230...96,176,677
Ensembl chr 6:95,949,991...96,176,677
JBrowse link
G Fzd6 frizzled class receptor 6 affects expression EXP Cocaine affects the expression of FZD6 mRNA CTD PMID:20187946 NCBI chr 7:70,055,012...70,086,781
Ensembl chr 7:70,055,068...70,086,776
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase increases expression EXP Cocaine results in increased expression of G6PD protein CTD PMID:25100957 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 affects expression
increases expression
decreases expression
EXP Cocaine affects the expression of GABBR1 mRNA
Cocaine results in increased expression of GABBR1 mRNA
Cocaine results in decreased expression of GABBR1 mRNA
CTD PMID:11793422 PMID:16076954 PMID:20187946 NCBI chr20:1,464,534...1,494,114
Ensembl chr20:1,464,534...1,493,994
JBrowse link
G Gabbr2 gamma-aminobutyric acid type B receptor subunit 2 decreases phosphorylation EXP Cocaine results in decreased phosphorylation of GABBR2 protein CTD PMID:12716959 NCBI chr 5:60,947,517...61,288,104
Ensembl chr 5:60,947,526...61,288,104
JBrowse link
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 affects expression
multiple interactions
EXP
ISO
Cocaine affects the expression of GABRA1 protein
Cocaine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]
1-(3-chlorophenyl)piperazine promotes the reaction [Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 3,4-Methylenedioxyamphetamine promotes the reaction [Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine promotes the reaction [1-(3-chlorophenyl)piperazine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine promotes the reaction [3,4-Methylenedioxyamphetamine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]
CTD PMID:20826313 PMID:23266428 PMID:32209479 NCBI chr10:26,595,151...26,650,611
Ensembl chr10:26,595,160...26,650,864
JBrowse link
G Gabrb1 gamma-aminobutyric acid type A receptor subunit beta1 increases expression EXP Cocaine results in increased expression of GABRB1 mRNA CTD PMID:17898221 NCBI chr14:36,068,725...36,548,946
Ensembl chr14:36,080,393...36,548,948
JBrowse link
G Gabrb2 gamma-aminobutyric acid type A receptor subunit beta 2 multiple interactions ISO
EXP
1-(3-chlorophenyl)piperazine promotes the reaction [Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 3,4-Methylenedioxyamphetamine promotes the reaction [Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine promotes the reaction [1-(3-chlorophenyl)piperazine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine promotes the reaction [3,4-Methylenedioxyamphetamine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]
Cocaine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]
CTD PMID:23266428 PMID:32209479 NCBI chr10:26,936,592...27,156,141
Ensembl chr10:26,936,551...27,151,251
JBrowse link
G Gabrb3 gamma-aminobutyric acid type A receptor subunit beta 3 affects expression
multiple interactions
EXP Cocaine affects the expression of GABRB3 mRNA
Cocaine affects the phosphorylation of and affects the expression of GABRB3 protein
CTD PMID:20187946 PMID:20826313 NCBI chr 1:108,467,047...108,702,522
Ensembl chr 1:108,296,124...108,698,961
JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 multiple interactions
increases expression
ISO
EXP
1-(3-chlorophenyl)piperazine promotes the reaction [Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 3,4-Methylenedioxyamphetamine promotes the reaction [Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine promotes the reaction [1-(3-chlorophenyl)piperazine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine promotes the reaction [3,4-Methylenedioxyamphetamine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]
Cocaine deficiency results in increased expression of GABRG2 mRNA
Cocaine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]
CTD PMID:23266428 PMID:27126842 PMID:32209479 NCBI chr10:26,376,805...26,463,680
Ensembl chr10:26,374,694...26,464,346
JBrowse link
G Gad1 glutamate decarboxylase 1 decreases expression
increases expression
ISO
EXP
Cocaine results in decreased expression of GAD1 mRNA
Cocaine results in increased expression of GAD1 protein
CTD PMID:12629581 PMID:15295023 PMID:18611417 NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333
JBrowse link
G Gal galanin and GMAP prepropeptide multiple interactions ISO GAL protein inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein]; GAL protein inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein] CTD PMID:19099295 NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:200,650,439...200,654,959
JBrowse link
G Galk1 galactokinase 1 affects expression EXP Cocaine affects the expression of GALK1 mRNA CTD PMID:20187946 NCBI chr10:101,243,146...101,247,323
Ensembl chr10:101,235,994...101,247,337
JBrowse link
G Galnt1 polypeptide N-acetylgalactosaminyltransferase 1 increases expression EXP Cocaine results in increased expression of GALNT1 mRNA CTD PMID:17898221 NCBI chr18:15,489,015...15,568,849
Ensembl chr18:15,489,020...15,568,245
JBrowse link
G Galnt16 polypeptide N-acetylgalactosaminyltransferase 16 affects expression EXP Cocaine affects the expression of GALNT16 mRNA CTD PMID:20187946 NCBI chr 6:100,168,943...100,250,718
Ensembl chr 6:100,170,306...100,250,705
JBrowse link
G Gap43 growth associated protein 43 decreases expression ISO Cocaine results in decreased expression of GAP43 mRNA CTD PMID:12629581 NCBI chr11:58,376,371...58,470,047
Ensembl chr11:58,376,371...58,470,045
JBrowse link
G Gas2 growth arrest-specific 2 affects expression ISO Cocaine affects the expression of GAS2 mRNA CTD PMID:15681117 NCBI chr 1:101,452,361...101,582,619
Ensembl chr 1:101,482,591...101,582,619
JBrowse link
G Gcc1 GRIP and coiled-coil domain containing 1 increases expression ISO Cocaine results in increased expression of GCC1 mRNA CTD PMID:17205118 NCBI chr 4:57,030,817...57,042,682
Ensembl chr 4:57,032,314...57,042,663
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression
multiple interactions
ISO Cocaine results in increased expression of GCLC mRNA
PRKCD protein affects the reaction [Cocaine results in increased expression of GCLC mRNA]; rottlerin promotes the reaction [Cocaine results in increased expression of GCLC mRNA]
CTD PMID:30393195 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit affects expression
increases expression
multiple interactions
EXP
ISO
Cocaine affects the expression of GCLM mRNA
Cocaine results in increased expression of GCLM mRNA
PRKCD protein affects the reaction [Cocaine results in increased expression of GCLM mRNA]; rottlerin promotes the reaction [Cocaine results in increased expression of GCLM mRNA]
CTD PMID:20187946 PMID:30393195 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Gcnt2 glucosaminyl (N-acetyl) transferase 2 (I blood group) increases expression ISO Cocaine deficiency results in increased expression of GCNT2 mRNA CTD PMID:27126842 NCBI chr17:23,796,859...23,901,625
Ensembl chr17:23,796,859...23,901,611
JBrowse link
G Gdap1 ganglioside-induced differentiation-associated-protein 1 increases expression EXP Cocaine results in increased expression of GDAP1 protein CTD PMID:25100957 NCBI chr 5:1,932,613...1,951,691
Ensembl chr 5:1,932,613...2,030,061
JBrowse link
G Gdap1l1 ganglioside-induced differentiation-associated protein 1-like 1 decreases expression EXP Cocaine results in decreased expression of GDAP1L1 protein CTD PMID:25100957 NCBI chr 3:152,110,225...152,129,693
Ensembl chr 3:152,110,253...152,128,711
JBrowse link
G Gdnf glial cell derived neurotrophic factor decreases expression EXP Cocaine results in decreased expression of GDNF mRNA CTD PMID:14622243 NCBI chr 2:56,893,992...56,919,935
Ensembl chr 2:56,895,010...56,917,209
JBrowse link
G Gem GTP binding protein overexpressed in skeletal muscle increases expression ISO Cocaine results in increased expression of GEM mRNA CTD PMID:15009677 NCBI chr 5:25,214,309...25,225,222
Ensembl chr 5:25,214,309...25,225,222
JBrowse link
G Gfap glial fibrillary acidic protein increases expression
decreases expression
affects expression
ISO
EXP
Cocaine results in increased expression of GFAP protein
Cocaine results in decreased expression of GFAP protein
Cocaine affects the expression of GFAP mRNA; Cocaine affects the expression of GFAP protein
CTD PMID:11391778 PMID:11882367 PMID:12670315 PMID:15814102 PMID:20187946 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
JBrowse link
G Gfra2 GDNF family receptor alpha 2 affects expression EXP Cocaine affects the expression of GFRA2 mRNA CTD PMID:12358776 NCBI chr15:45,941,841...46,033,715
Ensembl chr15:45,941,828...46,033,714
JBrowse link
G Gh1 growth hormone 1 multiple interactions ISO
EXP
Cocaine inhibits the reaction [4-hydroxybutyric acid results in increased secretion of GH1 protein]; Cocaine inhibits the reaction [Sodium Oxybate results in increased expression of GH1 protein]
Cocaine inhibits the reaction [Clonidine results in increased secretion of GH1 protein]
CTD PMID:9413023 PMID:10657535 PMID:15099682 NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078
JBrowse link
G Gid8 GID complex subunit 8 homolog affects expression EXP Cocaine affects the expression of GID8 mRNA CTD PMID:20187946 NCBI chr 3:167,826,006...167,836,759
Ensembl chr 3:167,826,060...167,834,814
JBrowse link
G Gimap1 GTPase, IMAP family member 1 affects expression EXP Cocaine affects the expression of GIMAP1 mRNA CTD PMID:20187946 NCBI chr 4:77,687,581...77,691,468
Ensembl chr 4:77,682,171...77,691,866
JBrowse link
G Gimap5 GTPase, IMAP family member 5 affects expression EXP Cocaine affects the expression of GIMAP5 mRNA CTD PMID:20187946 NCBI chr 4:77,693,417...77,701,025
Ensembl chr 4:77,687,564...77,703,086
JBrowse link
G Gins3 GINS complex subunit 3 decreases expression EXP Cocaine results in decreased expression of GINS3 mRNA CTD PMID:27899881 NCBI chr19:9,420,085...9,428,621
Ensembl chr19:9,420,086...9,428,687
JBrowse link
G Gipc1 GIPC PDZ domain containing family, member 1 affects expression EXP Cocaine affects the expression of GIPC1 mRNA CTD PMID:20187946 NCBI chr19:24,474,291...24,487,083
Ensembl chr19:24,453,123...24,486,997
JBrowse link
G Gja5 gap junction protein, alpha 5 increases expression EXP Cocaine results in increased expression of GJA5 mRNA CTD PMID:27899881 NCBI chr 2:184,602,407...184,621,952
Ensembl chr 2:184,564,475...184,621,952
JBrowse link
G Gjb1 gap junction protein, beta 1 affects expression EXP Cocaine affects the expression of GJB1 mRNA; Cocaine affects the expression of GJB1 protein CTD PMID:10510198 NCBI chr  X:66,501,848...66,509,783
Ensembl chr  X:66,501,820...66,509,925
JBrowse link
G Gjb2 gap junction protein, beta 2 decreases expression ISO Cocaine results in decreased expression of GJB2 mRNA CTD PMID:12629581 NCBI chr15:31,260,390...31,278,222
Ensembl chr15:31,260,357...31,278,177
JBrowse link
G Gjb5 gap junction protein, beta 5 decreases expression EXP Cocaine results in decreased expression of GJB5 mRNA CTD PMID:27899881 NCBI chr 5:139,680,670...139,683,588
Ensembl chr 5:139,680,671...139,683,583
JBrowse link
G Gjd2 gap junction protein, delta 2 affects expression EXP Cocaine affects the expression of GJD2 mRNA; Cocaine affects the expression of GJD2 protein CTD PMID:16138316 NCBI chr 3:100,771,450...100,776,134
Ensembl chr 3:100,772,062...100,775,061
JBrowse link
G Gli2 GLI family zinc finger 2 decreases expression EXP Cocaine results in decreased expression of GLI2 mRNA CTD PMID:27899881 NCBI chr13:29,946,809...30,163,901
Ensembl chr13:29,946,809...30,163,574
JBrowse link
G Glp2r glucagon-like peptide 2 receptor decreases expression EXP Cocaine results in decreased expression of GLP2R mRNA CTD PMID:17898221 NCBI chr10:52,402,748...52,465,908
Ensembl chr10:52,402,748...52,466,012
JBrowse link
G Glra1 glycine receptor, alpha 1 multiple interactions EXP Cocaine inhibits the reaction [Glycine results in increased activity of GLRA1 protein]; Dronabinol inhibits the reaction [Cocaine inhibits the reaction [Glycine results in increased activity of GLRA1 protein]] CTD PMID:32209479 NCBI chr10:39,625,853...39,727,897
Ensembl chr10:39,629,459...39,727,162
JBrowse link
G Glrx3 glutaredoxin 3 affects expression EXP Cocaine affects the expression of GLRX3 mRNA CTD PMID:20187946 NCBI chr 1:192,241,707...192,272,012
Ensembl chr 1:192,241,701...192,272,010
JBrowse link
G Gnao1 G protein subunit alpha o1 decreases expression
multiple interactions
ISO
EXP
Cocaine results in decreased expression of GNAO1 mRNA
[Cocaine affects the activity of PRKACA protein] which affects the phosphorylation of GNAO1 protein alternative form
CTD PMID:12629581 PMID:19457111 NCBI chr19:11,034,874...11,192,502
Ensembl chr19:11,035,956...11,192,493
JBrowse link
G Gnat1 G protein subunit alpha transducin 1 increases expression EXP Cocaine results in increased expression of GNAT1 mRNA CTD PMID:27899881 NCBI chr 8:108,350,935...108,355,671
Ensembl chr 8:108,350,935...108,355,671
JBrowse link
G Gnb1 G protein subunit beta 1 decreases expression
increases expression
ISO
EXP
Cocaine results in decreased expression of GNB1 mRNA
Cocaine results in increased expression of GNB1 mRNA
CTD PMID:12629581 PMID:16076954 NCBI chr 5:166,075,508...166,142,223
Ensembl chr 5:166,075,629...166,142,124
JBrowse link
G Gnb2 G protein subunit beta 2 affects expression EXP Cocaine affects the expression of GNB2 mRNA CTD PMID:20187946 NCBI chr12:19,159,002...19,164,021
Ensembl chr12:19,158,973...19,164,019
JBrowse link
G Gnb4 G protein subunit beta 4 multiple interactions ISO HDAC5 affects the reaction [Cocaine affects the expression of GNB4 mRNA] CTD PMID:17988634 NCBI chr 2:115,360,746...115,400,680
Ensembl chr 2:115,364,918...115,400,579
JBrowse link
G Gng12 G protein subunit gamma 12 affects expression EXP Cocaine affects the expression of GNG12 mRNA CTD PMID:20187946 NCBI chr 4:96,011,118...96,134,767
Ensembl chr 4:96,010,952...96,134,712
JBrowse link
G Gnrh1 gonadotropin releasing hormone 1 decreases expression
multiple interactions
ISO Cocaine results in decreased expression of GNRH1 protein
GPX1 protein inhibits the reaction [Cocaine results in decreased expression of GNRH1 protein]; prolinedithiocarbamate inhibits the reaction [Cocaine results in decreased expression of GNRH1 protein]
CTD PMID:31059705 NCBI chr15:41,972,482...41,976,690
Ensembl chr15:41,972,905...41,973,581
Ensembl chr15:41,972,905...41,973,581
JBrowse link
G Gp2 glycoprotein 2 affects expression EXP Cocaine affects the expression of GP2 mRNA CTD PMID:20187946 NCBI chr 1:173,797,057...173,812,619
Ensembl chr 1:173,797,057...173,812,619
JBrowse link
G Gpc5 glypican 5 increases expression
multiple interactions
ISO Cocaine results in increased expression of GPC5 mRNA
FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of GPC5 mRNA]
CTD PMID:18355967 NCBI chr15:92,207,275...93,644,054
Ensembl chr15:92,239,176...93,643,282
JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 increases expression EXP Cocaine results in increased expression of GPER1 mRNA CTD PMID:17898221 NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889
JBrowse link
G Gphn gephyrin increases phosphorylation
multiple interactions
EXP Cocaine results in increased phosphorylation of GPHN protein
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone promotes the reaction [Cocaine results in increased phosphorylation of GPHN protein]
CTD PMID:32312805 NCBI chr 6:96,954,365...97,483,617
Ensembl chr 6:96,892,148...97,483,612
JBrowse link
G Gpm6a glycoprotein m6a decreases expression ISO Cocaine results in decreased expression of GPM6A mRNA CTD PMID:12629581 NCBI chr16:36,641,282...36,973,477
Ensembl chr16:36,641,284...36,973,475
JBrowse link
G Gpm6b glycoprotein m6b decreases expression ISO Cocaine results in decreased expression of GPM6B mRNA CTD PMID:12629581 NCBI chr  X:28,057,788...28,204,409
Ensembl chr  X:28,059,450...28,204,211
JBrowse link
G Gpr157 G protein-coupled receptor 157 decreases expression EXP Cocaine results in decreased expression of GPR157 mRNA CTD PMID:27899881 NCBI chr 5:160,550,703...160,566,432
Ensembl chr 5:160,550,713...160,566,432
JBrowse link
G Gpr3 G protein-coupled receptor 3 increases expression EXP Cocaine results in increased expression of GPR3 mRNA CTD PMID:27899881 NCBI chr 5:145,411,500...145,414,621
Ensembl chr 5:145,411,510...145,414,590
JBrowse link
G Gpr88 G-protein coupled receptor 88 affects expression
increases expression
EXP
ISO
Cocaine affects the expression of GPR88 mRNA
Cocaine deficiency results in increased expression of GPR88 mRNA
CTD PMID:20187946 PMID:27126842 NCBI chr 2:204,191,443...204,199,576
Ensembl chr 2:204,191,427...204,199,733
JBrowse link
G Gprasp1 G protein-coupled receptor associated sorting protein 1 affects expression EXP Cocaine affects the expression of GPRASP1 mRNA CTD PMID:20187946 NCBI chr  X:98,765,581...98,772,685
Ensembl chr  X:98,709,841...98,772,851
JBrowse link
G Gpsm1 G-protein signaling modulator 1 affects expression EXP Cocaine affects the expression of GPSM1 protein CTD PMID:15091342 NCBI chr 3:9,140,816...9,167,828
Ensembl chr 3:9,128,636...9,167,827
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions
increases activity
ISO PRKCD protein affects the reaction [Cocaine results in increased activity of GPT protein]; rottlerin inhibits the reaction [Cocaine results in increased activity of GPT protein] CTD PMID:30393195 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression
affects response to substance
multiple interactions
ISO Cocaine results in increased expression of GPX1 protein
GPX1 protein affects the susceptibility to Cocaine
GPX1 protein affects the susceptibility to [Cocaine co-treated with prolinedithiocarbamate]; GPX1 protein inhibits the reaction [Cocaine affects the localization of RELA protein]; GPX1 protein inhibits the reaction [Cocaine results in decreased expression of GNRH1 protein]; GPX1 protein inhibits the reaction [Cocaine results in increased activity of and affects the localization of RELA protein]; GPX1 protein inhibits the reaction [Cocaine results in increased expression of FOS protein]; prolinedithiocarbamate promotes the reaction [Cocaine results in increased expression of GPX1 protein]
CTD PMID:31059705 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Grb2 growth factor receptor bound protein 2 increases expression EXP Cocaine results in increased expression of GRB2 protein CTD PMID:25100957 NCBI chr10:100,881,404...100,949,193
Ensembl chr10:100,869,718...100,949,309
JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 decreases response to substance
decreases expression
increases phosphorylation
affects response to substance
increases response to substance
increases expression
decreases phosphorylation
multiple interactions
affects expression
ISO
EXP
GRIA1 results in decreased susceptibility to Cocaine
Cocaine results in decreased expression of GRIA1 mRNA; Cocaine results in decreased expression of GRIA1 protein
Cocaine results in increased phosphorylation of GRIA1 protein
GRIA1 protein affects the susceptibility to Cocaine
GRIA1 protein results in increased susceptibility to Cocaine
GRIA1 protein mutant form results in decreased susceptibility to Cocaine; GRIA1 results in decreased susceptibility to Cocaine
Cocaine results in increased expression of GRIA1 mRNA; Cocaine results in increased expression of GRIA1 protein
Cocaine results in decreased phosphorylation of GRIA1 protein
6-methyl-2-(phenylethynyl)pyridine affects the reaction [Cocaine affects the phosphorylation of GRIA1 protein]; Cocaine affects the phosphorylation of and affects the expression of GRIA1 protein; Cocaine results in increased phosphorylation of and results in increased transport of GRIA1 protein; Dizocilpine Maleate inhibits the reaction [Cocaine results in increased expression of GRIA1 protein]; ifenprodil inhibits the reaction [Cocaine results in increased expression of GRIA1 protein]; ILK mutant form inhibits the reaction [Cocaine results in increased phosphorylation of GRIA1 protein]; Ondansetron inhibits the reaction [Cocaine results in increased phosphorylation of GRIA1 protein]; roscovitine inhibits the reaction [Cocaine results in decreased phosphorylation of GRIA1 protein]; U 0126 inhibits the reaction [Cocaine results in increased expression of GRIA1 protein]
Cocaine affects the expression of GRIA1 mRNA; Cocaine affects the expression of GRIA1 protein
Cocaine results in increased expression of and results in increased phosphorylation of GRIA1 protein; Nifedipine inhibits the reaction [Cocaine results in increased expression of and results in increased phosphorylation of GRIA1 protein]; resveratrol promotes the reaction [Cocaine results in increased phosphorylation of GRIA1 protein]; SL 327 inhibits the reaction [Cocaine results in increased phosphorylation of GRIA1 protein]
CTD PMID:9886066 PMID:11268215