CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: 1-stearoyl-2-arachidonoyl-sn-glycerol
Accession: CHEBI:75728
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Definition: A 1,2-diacyl-sn-glycerol in which the acyl groups at positions 1 and 2 are specifed as stearoyl and arachidonoyl respectively.
Synonyms: exact_synonym: (2S)-1-hydroxy-3-(octadecanoyloxy)propan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate
related_synonym: (2S)-1-hydroxy-3-(stearoyloxy)propan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate; 1-Stearoyl-2-arachidonoylglycerol; 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol; DAG(18:0/20:4); DAG(18:0/20:4omega6); DAG(38:4); DG(18:0/20:4(5Z,8Z,11Z,14Z)/0:0); DG(18:0/20:4(5Z,8Z,11Z,14Z)/0:0)[iso2]; DG(18:0/20:4(omega-6)/0:0); DG(18:0/20:4); DG(18:0/20:4/0:0)[iso2]; DG(18:0/20:4omega6); DG(38:4); Diacylglycerol(18:0/20:4); Diacylglycerol(18:0/20:4omega6); Diacylglycerol(38:4); Formula=C41H72O5; InChI=1S/C41H72O5/c1-3-5-7-9-11-13-15-17-19-20-22-24-26-28-30-32-34-36-41(44)46-39(37-42)38-45-40(43)35-33-31-29-27-25-23-21-18-16-14-12-10-8-6-4-2/h11,13,17,19,22,24,28,30,39,42H,3-10,12,14-16,18,20-21,23,25-27,29,31-38H2,1-2H3/b13-11-,19-17-,24-22-,30-28-/t39-/m0/s1; InChIKey=NSXLMTYRMFVYNT-IUJDHQGTSA-N; SMILES=CCCCCCCCCCCCCCCCCC(=O)OC[C@H](CO)OC(=O)CCC\\C=C/C\\C=C/C\\C=C/C\\C=C/CCCCC
xref: CAS:65914-84-3; HMDB:HMDB0007170; LIPID_MAPS_instance:LMGL02010111
xref_mesh: MESH:C075809
xref: Reaxys:7755101
G
Col1a1
collagen type I alpha 1 chain
multiple interactions
ISO
1-stearoyl-2-arachidonoylglycerol inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]
CTD
PMID:27936102
NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
G
Dagla
diacylglycerol lipase, alpha
increases metabolic processing
ISO
DAGLA protein results in increased metabolism of 1-stearoyl-2-arachidonoylglycerol
CTD
PMID:18657971
NCBI chr 1:206,890,635...206,947,332
Ensembl chr 1:206,890,638...206,947,232
G
Daglb
diacylglycerol lipase, beta
increases metabolic processing
ISO
DAGLB protein results in increased metabolism of 1-stearoyl-2-arachidonoylglycerol
CTD
PMID:18657971
NCBI chr12:11,059,732...11,102,170
Ensembl chr12:11,059,732...11,102,154
G
Dgke
diacylglycerol kinase epsilon
increases phosphorylation
ISO
DGKE protein results in increased phosphorylation of 1-stearoyl-2-arachidonoylglycerol
CTD
PMID:17455907
NCBI chr10:73,853,030...73,877,334
Ensembl chr10:73,855,583...73,877,100
G
Ppargc1a
PPARG coactivator 1 alpha
increases expression
ISO
1-stearoyl-2-arachidonoylglycerol results in increased expression of PPARGC1A mRNA
CTD
PMID:23056435
NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
G
Tgfb1
transforming growth factor, beta 1
multiple interactions
ISO
1-stearoyl-2-arachidonoylglycerol inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]
CTD
PMID:27936102
NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
G
Trpm6
transient receptor potential cation channel, subfamily M, member 6
multiple interactions
ISO
TRPM6 protein affects the reaction [1-stearoyl-2-arachidonoylglycerol results in increased transport of Barium]; TRPM6 protein affects the reaction [1-stearoyl-2-arachidonoylglycerol results in increased transport of Calcium]
CTD
PMID:11988098
NCBI chr 1:216,136,407...216,320,523
Ensembl chr 1:216,170,038...216,320,520
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