CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
Becn1
beclin 1
increases expression
ISO
beta-thujaplicin results in increased expression of BECN1 protein
CTD
PMID:25044443
NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,231,388...86,246,742
G
Mtor
mechanistic target of rapamycin kinase
decreases phosphorylation
ISO
beta-thujaplicin results in decreased phosphorylation of MTOR protein
CTD
PMID:25044443
NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:158,884,804...158,994,311
G
Rps6kb1
ribosomal protein S6 kinase B1
decreases phosphorylation
ISO
beta-thujaplicin results in decreased phosphorylation of RPS6KB1 protein
CTD
PMID:25044443
NCBI chr10:71,817,794...71,865,211
Ensembl chr10:71,323,777...71,367,908
G
Sqstm1
sequestosome 1
decreases expression
ISO
beta-thujaplicin results in decreased expression of SQSTM1 protein
CTD
PMID:25044443
NCBI chr10:35,026,598...35,037,750
Ensembl chr10:34,525,519...34,536,673
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
Comt
catechol-O-methyltransferase
decreases activity
EXP
Tropolone results in decreased activity of COMT protein
CTD
PMID:10064789
NCBI chr11:96,072,371...96,091,956
Ensembl chr11:82,568,025...82,587,642
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all