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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:difenoxin
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Accession:CHEBI:4534 term browser browse the term
Definition:A piperidinemonocarboxylic acid that is 4-phenylpiperidine-4-carboxylic acid in which the hydrogen attached to the nitrogen atom is substituted by a 3-cyano-3,3-diphenylpropyl group.
Synonyms:exact_synonym: 1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylic acid
 related_synonym: 1-(3-cyano-3,3-diphenylpropyl)-4-phenylisonipecotic acid;   Formula=C28H28N2O2;   InChI=1S/C28H28N2O2/c29-22-28(24-12-6-2-7-13-24,25-14-8-3-9-15-25)18-21-30-19-16-27(17-20-30,26(31)32)23-10-4-1-5-11-23/h1-15H,16-21H2,(H,31,32);   InChIKey=UFIVBRCCIRTJTN-UHFFFAOYSA-N;   SMILES=OC(=O)C1(CCN(CC1)CCC(C#N)(c1ccccc1)c1ccccc1)c1ccccc1;   difenoxina;   difenoxinum;   diphenoxilic acid;   diphenoxylic acid
 xref: Beilstein:6827931;   CAS:28782-42-5;   DrugBank:DB01501;   Drug_Central:878;   KEGG:C07871;   KEGG:D03809;   Patent:DE1953342;   Patent:US3646207;   Wikipedia:Difenoxin


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diphenoxylate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tp53 tumor protein p53 affects activity ISO Diphenoxylate affects the activity of TP53 protein CTD PMID:35435491 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    chemical entity 19806
      group 19765
        pseudohalo group 4566
          cyano group 4566
            nitrile 4566
              difenoxin 1
                difenoxin hydrochloride 0
                diphenoxylate + 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19806
      composite particle 19806
        hadron 19806
          baryon 19806
            nucleon 19806
              atomic nucleus 19806
                atom 19806
                  main group element atom 19756
                    main group molecular entity 19756
                      s-block molecular entity 19595
                        hydrogen molecular entity 19582
                          hydrides 19095
                            inorganic hydride 18093
                              pnictogen hydride 18082
                                nitrogen hydride 17989
                                  azane 17798
                                    ammonia 17797
                                      organic amino compound 17797
                                        tertiary amino compound 10131
                                          tertiary amine 640
                                            difenoxin 1
                                              difenoxin hydrochloride 0
                                              diphenoxylate + 1
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