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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:butyrylthiocholine
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Accession:CHEBI:41055 term browser browse the term
Definition:A quaternary ammonium ion obtained by the formal condensation of the carboxy group of butyric acid with the thiol group of thiocholine. It is used as a reagent for determination of butyrylcholinesterase activity.
Synonyms:exact_synonym: 2-(butanoylsulfanyl)-N,N,N-trimethylethan-1-aminium
 related_synonym: Formula=C9H20NOS;   InChI=1S/C9H20NOS/c1-5-6-9(11)12-8-7-10(2,3)4/h5-8H2,1-4H3/q+1;   InChIKey=AWBGQVBMGBZGLS-UHFFFAOYSA-N;   S-butanoylthiocholine;   S-butyrylthiocholine;   SMILES=CCCC(=O)SCC[N+](C)(C)C;   butanoylthiocholine
 xref: CAS:4555-00-4;   DrugBank:DB04250
 xref_mesh: MESH:D002092
 xref: PDBeChem:BCH;   PMID:25450746;   PMID:25486543;   Reaxys:1777055


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butyrylthiocholine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase increases hydrolysis
multiple interactions		 ISO ACHE protein results in increased hydrolysis of Butyrylthiocholine
huperzine A inhibits the reaction [ACHE protein results in increased hydrolysis of Butyrylthiocholine]		 CTD PMID:22407886 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Bche butyrylcholinesterase multiple interactions
increases hydrolysis
increases metabolic processing		 ISO
EXP		 [BCHE protein results in increased metabolism of Butyrylthiocholine] which results in increased chemical synthesis of Thiocholine; butyrylcholine inhibits the reaction [BCHE protein results in increased hydrolysis of Butyrylthiocholine]; Cholinesterase Inhibitors inhibits the reaction [BCHE protein results in increased hydrolysis of Butyrylthiocholine]; Dibucaine inhibits the reaction [BCHE protein results in increased metabolism of Butyrylthiocholine]; Echothiophate Iodide inhibits the reaction [BCHE protein results in increased hydrolysis of Butyrylthiocholine]; Isoflurophate inhibits the reaction [BCHE protein results in increased hydrolysis of Butyrylthiocholine]; N,N'-monomethylenebis(pyridiniumaldoxime) inhibits the reaction [Sarin analog inhibits the reaction [BCHE protein results in increased hydrolysis of Butyrylthiocholine]]; pralidoxime inhibits the reaction [Isoflurophate inhibits the reaction [BCHE protein results in increased hydrolysis of Butyrylthiocholine]]; pralidoxime inhibits the reaction [Sarin analog inhibits the reaction [BCHE protein results in increased hydrolysis of Butyrylthiocholine]]; profenamine inhibits the reaction [BCHE protein results in increased hydrolysis of Butyrylthiocholine]; Sarin analog inhibits the reaction [BCHE protein results in increased hydrolysis of Butyrylthiocholine]; Sodium Fluoride inhibits the reaction [BCHE protein results in increased metabolism of Butyrylthiocholine] CTD PMID:19699221 PMID:21802514 PMID:22407886 PMID:22922115 PMID:22940283 More... NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19844
    chemical entity 19842
      molecular entity 19842
        ion 16715
          organic ion 9898
            organic cation 8956
              quaternary ammonium ion 5287
                butyrylthiocholine 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19844
    subatomic particle 19842
      composite particle 19842
        hadron 19842
          baryon 19842
            nucleon 19809
              atomic nucleus 19842
                atom 19842
                  main group element atom 19792
                    main group molecular entity 19792
                      s-block molecular entity 19626
                        hydrogen molecular entity 19613
                          hydrides 19115
                            inorganic hydride 18121
                              pnictogen hydride 18110
                                nitrogen hydride 18017
                                  ammonium 8317
                                    ammonium ion derivative 8291
                                      quaternary ammonium ion 5287
                                        butyrylthiocholine 2
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