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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69313
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ache
Name: acetylcholinesterase
Acc ID: CHEBI:41055
Term: butyrylthiocholine
Definition: A quaternary ammonium ion obtained by the formal condensation of the carboxy group of butyric acid with the thiol group of thiocholine. It is used as a reagent for determination of butyrylcholinesterase activity.
Chemical ID: MESH:D002092
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Acheincreases hydrolysisISORGD:7358786480464CTDACHE protein results in increased hydrolysis of Butyrylthiocholine

PMID:22407886
Achemultiple interactionsISORGD:7358786480464CTDhuperzine A inhibits the reaction [ACHE protein results in increased hydrolysis of Butyrylthiocholine]

PMID:22407886
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