CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: triazophos
Accession: CHEBI:38963
browse the term
Definition: An organothiophosphate insecticide that has formula C12H16N3O3PS.
Synonyms: exact_synonym: O,O-diethyl O-(1-phenyl-1H-1,2,4-triazol-3-yl) phosphorothioate
related_synonym: 1-Phenyl-1,2,4-triazolyl-3-(O,O-diethylthionophosphate); Formula=C12H16N3O3PS; Hostathion; InChI=1S/C12H16N3O3PS/c1-3-16-19(20,17-4-2)18-12-13-10-15(14-12)11-8-6-5-7-9-11/h5-10H,3-4H2,1-2H3; InChIKey=AMFGTOFWMRQMEM-UHFFFAOYSA-N; Methoxone; O,O-diethyl O-(1-phenyl-1H-1,2,4-triazol-3-yl) thiophosphate; Phosphorothioic acid, O,O-diethyl O-(1-phenyl-1H-1,2,4-triazol-3-yl) ester; SMILES=CCOP(=S)(OCC)Oc1ncn(n1)-c1ccccc1; Triazofos
xref: CAS:24017-47-8; KEGG:C18657
xref_mesh: MESH:C012584
xref: PPDB:653
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
Ache
acetylcholinesterase
decreases activity
ISO
triazophos metabolite results in decreased activity of ACHE protein; triazophos results in decreased activity of ACHE protein
CTD
PMID:33844597
NCBI chr 5:137,286,516...137,292,728
Ensembl chr 5:137,285,781...137,292,728
G
Bdnf
brain derived neurotrophic factor
decreases expression
ISO
triazophos results in decreased expression of BDNF mRNA; triazophos results in decreased expression of BDNF protein
CTD
PMID:23949197
NCBI chr 2:109,505,045...109,557,388
Ensembl chr 2:109,505,045...109,557,352
G
Gip
gastric inhibitory polypeptide
decreases secretion
ISO
triazophos results in decreased secretion of GIP protein
CTD
PMID:34038317
NCBI chr11:95,915,358...95,921,657
Ensembl chr11:95,915,371...95,921,657
G
Il6
interleukin 6
decreases secretion
ISO
triazophos results in decreased secretion of IL6 protein
CTD
PMID:34038317
NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
G
Lep
leptin
decreases secretion
ISO
triazophos results in decreased secretion of LEP protein
CTD
PMID:34038317
NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876
G
Pyy
peptide YY
decreases secretion
ISO
triazophos results in decreased secretion of PYY protein
CTD
PMID:34038317
NCBI chr11:101,997,502...101,998,658
Ensembl chr11:101,997,502...101,998,658
G
Trp53
transformation related protein 53
affects activity
ISO
triazophos metabolite affects the activity of TP53 protein
CTD
PMID:35435491
NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
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