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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:threonine
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Accession:CHEBI:26986 term browser browse the term
Definition:An alpha-amino acid in which one of the hydrogens attached to the alpha-carbon of glycine is substituted by a 1-hydroxyethyl group.
Synonyms:related_synonym: Formula=C4H9NO3;   Threonin
 xref: Beilstein:8204750;   CAS:80-68-2;   PMID:11379295;   PMID:15221503;   PMID:22264337;   Wikipedia:Threonine
 cyclic_relationship: is_conjugate_acid_of CHEBI:32832;   is_conjugate_base_of CHEBI:32833


show annotations for term's descendants           Sort by:
L-threonine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO [[MPO protein co-treated with Chlorides co-treated with Threonine co-treated with Hydrogen Peroxide] results in increased chemical synthesis of Acrolein] which results in increased phosphorylation of AKT1 protein; resorcinol inhibits the reaction [[[MPO protein co-treated with Chlorides co-treated with Threonine co-treated with Hydrogen Peroxide] results in increased chemical synthesis of Acrolein] which results in increased phosphorylation of AKT1 protein]; Wortmannin inhibits the reaction [[[MPO protein co-treated with Chlorides co-treated with Threonine co-treated with Hydrogen Peroxide] results in increased chemical synthesis of Acrolein] which results in increased phosphorylation of AKT1 protein] CTD PMID:26262998 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Mpo myeloperoxidase multiple interactions ISO [[MPO protein co-treated with Chlorides co-treated with Threonine co-treated with Hydrogen Peroxide] results in increased chemical synthesis of Acrolein] which results in increased phosphorylation of AKT1 protein; [MPO protein co-treated with Chlorides co-treated with Threonine co-treated with Hydrogen Peroxide] results in increased chemical synthesis of Acrolein; resorcinol inhibits the reaction [[[MPO protein co-treated with Chlorides co-treated with Threonine co-treated with Hydrogen Peroxide] results in increased chemical synthesis of Acrolein] which results in increased phosphorylation of AKT1 protein]; Wortmannin inhibits the reaction [[[MPO protein co-treated with Chlorides co-treated with Threonine co-treated with Hydrogen Peroxide] results in increased chemical synthesis of Acrolein] which results in increased phosphorylation of AKT1 protein] CTD PMID:26262998 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19898
    role 19868
      application 19714
        NMR chemical shift reference compound 18086
          ammonia 17885
            organic amino compound 17885
              amino acid 16072
                polar amino acid 11705
                  threonine 2
                    D-threonine + 0
                    L-threonine + 2
                    gamma-glutamylthreonine + 0
                    threonin-O(3)-yl group + 0
                    threonine derivative + 0
                    threonine residue + 0
                    threonino group + 0
                    threonyl group + 0
                    threonyl-3-sulfoalanine 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19898
    subatomic particle 19896
      composite particle 19896
        hadron 19896
          baryon 19896
            nucleon 19896
              atomic nucleus 19896
                atom 19896
                  main group element atom 19835
                    main group molecular entity 19835
                      s-block molecular entity 19670
                        hydrogen molecular entity 19651
                          hydrides 19158
                            inorganic hydride 18176
                              pnictogen hydride 18166
                                nitrogen hydride 18079
                                  azane 17886
                                    ammonia 17885
                                      organic amino compound 17885
                                        amino acid 16072
                                          alpha-amino acid 13946
                                            2-amino-3-hydroxybutanoic acid 2
                                              threonine 2
                                                D-threonine + 0
                                                L-threonine + 2
                                                gamma-glutamylthreonine + 0
                                                threonin-O(3)-yl group + 0
                                                threonine derivative + 0
                                                threonine residue + 0
                                                threonino group + 0
                                                threonyl group + 0
                                                threonyl-3-sulfoalanine 0
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