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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:2-amino-3-hydroxybutanoic acid
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Accession:CHEBI:38263 term browser browse the term
Definition:An alpha-amino acid that is butanoic acid substituted by an amino group at position 2 and a hydroxy group at position 3.
Synonyms:related_synonym: Formula=C4H9NO3;   InChI=1S/C4H9NO3/c1-2(6)3(5)4(7)8/h2-3,6H,5H2,1H3,(H,7,8);   InChIKey=AYFVYJQAPQTCCC-UHFFFAOYSA-N;   SMILES=CC(O)C(N)C(O)=O
 xref: Beilstein:1098902



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Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO [[MPO protein co-treated with Chlorides co-treated with Threonine co-treated with Hydrogen Peroxide] results in increased chemical synthesis of Acrolein] which results in increased phosphorylation of AKT1 protein; resorcinol inhibits the reaction [[[MPO protein co-treated with Chlorides co-treated with Threonine co-treated with Hydrogen Peroxide] results in increased chemical synthesis of Acrolein] which results in increased phosphorylation of AKT1 protein]; Wortmannin inhibits the reaction [[[MPO protein co-treated with Chlorides co-treated with Threonine co-treated with Hydrogen Peroxide] results in increased chemical synthesis of Acrolein] which results in increased phosphorylation of AKT1 protein] CTD PMID:26262998 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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G Mpo myeloperoxidase multiple interactions ISO [[MPO protein co-treated with Chlorides co-treated with Threonine co-treated with Hydrogen Peroxide] results in increased chemical synthesis of Acrolein] which results in increased phosphorylation of AKT1 protein; [MPO protein co-treated with Chlorides co-treated with Threonine co-treated with Hydrogen Peroxide] results in increased chemical synthesis of Acrolein; resorcinol inhibits the reaction [[[MPO protein co-treated with Chlorides co-treated with Threonine co-treated with Hydrogen Peroxide] results in increased chemical synthesis of Acrolein] which results in increased phosphorylation of AKT1 protein]; Wortmannin inhibits the reaction [[[MPO protein co-treated with Chlorides co-treated with Threonine co-treated with Hydrogen Peroxide] results in increased chemical synthesis of Acrolein] which results in increased phosphorylation of AKT1 protein] CTD PMID:26262998 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19918
    role 19894
      biological role 19892
        biochemical role 19588
          metabolite 19574
            eukaryotic metabolite 19387
              plant metabolite 17985
                2-amino-3-hydroxybutanoic acid 2
                  allothreonine + 0
                  threonine + 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19918
    subatomic particle 19916
      composite particle 19916
        hadron 19916
          baryon 19916
            nucleon 19916
              atomic nucleus 19916
                atom 19916
                  main group element atom 19866
                    p-block element atom 19866
                      carbon group element atom 19811
                        carbon atom 19806
                          organic molecular entity 19806
                            organic group 18995
                              organic divalent group 18969
                                organodiyl group 18969
                                  carbonyl group 18922
                                    carbonyl compound 18922
                                      carboxylic acid 18646
                                        amino acid 15961
                                          alpha-amino acid 13870
                                            2-amino-3-hydroxybutanoic acid 2
                                              allothreonine + 0
                                              threonine + 2
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