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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Methylacrylonitrile
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Accession:CHEBI:229308 term browser browse the term
Synonyms:exact_synonym: 2-methylprop-2-enenitrile
 related_synonym: Formula=C4H5N;   InChI=1S/C4H5N/c1-4(2)3-5/h1H2,2H3;   InChIKey=GYCMBHHDWRMZGG-UHFFFAOYSA-N;   SMILES=N#CC(C)=C
 xref: CAS:126-98-7;   Chemspider:29101;   HMDB:HMDB0254515
 xref_mesh: MESH:C008385


show annotations for term's descendants           Sort by:
Methylacrylonitrile term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cat catalase decreases activity EXP methacrylonitrile results in decreased activity of CAT protein CTD PMID:15865260 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases expression
multiple interactions
increases metabolic processing
increases activity		 EXP
ISO		 methacrylonitrile results in increased expression of CYP2E1 mRNA; methacrylonitrile results in increased expression of CYP2E1 protein
[CYP2E1 protein results in increased metabolism of methacrylonitrile] which results in increased abundance of Cyanides
methacrylonitrile results in increased activity of CYP2E1 protein		 CTD PMID:10215687 PMID:11939710 PMID:15893539 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    chemical entity 19806
      group 19765
        pseudohalo group 4566
          cyano group 4566
            nitrile 4566
              Methylacrylonitrile 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19806
      composite particle 19806
        hadron 19806
          baryon 19806
            nucleon 19806
              atomic nucleus 19806
                atom 19806
                  main group element atom 19756
                    p-block element atom 19756
                      carbon group element atom 19705
                        carbon atom 19702
                          organic molecular entity 19702
                            one-carbon compound 17847
                              hydrogen cyanide 4782
                                cyanides 4765
                                  nitrile 4566
                                    Methylacrylonitrile 2
paths to the root