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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Omeprazole sulfide
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Accession:CHEBI:188255 term browser browse the term
Synonyms:exact_synonym: 6-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulanyl]-1H-benzimidazole
 related_synonym: Formula=C17H19N3O2S;   InChI=1S/C17H19N3O2S/c1-10-8-18-15(11(2)16(10)22-4)9-23-17-19-13-6-5-12(21-3)7-14(13)20-17/h5-8H,9H2,1-4H3,(H,19,20);   InChIKey=XURCIPRUUASYLR-UHFFFAOYSA-N;   SMILES=S(CC1=NC=C(C(OC)=C1C)C)C=2NC3=C(N2)C=CC(OC)=C3
 xref: CAS:73590-85-9;   Chemspider:137229
 xref_mesh: MESH:C040449
 xref: PDBeChem:1C6


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Omeprazole sulfide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions ISO omeprazole sulfide inhibits the reaction [Methylcholanthrene results in increased activity of AHR protein]; omeprazole sulfide inhibits the reaction [Omeprazole results in increased activity of AHR protein]; omeprazole sulfide inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]
omeprazole sulfide binds to and affects the folding of AHR protein; omeprazole sulfide binds to and results in decreased activity of AHR protein; omeprazole sulfide inhibits the reaction [Methylcholanthrene results in increased activity of AHR protein]; omeprazole sulfide inhibits the reaction [Tetrachlorodibenzodioxin affects the localization of AHR protein]; omeprazole sulfide inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]; omeprazole sulfide inhibits the reaction [Tetrachlorodibenzodioxin results in increased degradation of AHR protein]		 CTD PMID:16109480 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression		 ISO omeprazole sulfide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; omeprazole sulfide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]
omeprazole sulfide results in increased expression of CYP1A1 mRNA		 CTD PMID:16109480 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases metabolic processing ISO CYP3A4 protein results in increased metabolism of omeprazole sulfide CTD PMID:16109480 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
Term paths to the root
Path 1
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  CHEBI ontology 19898
    chemical entity 19896
      atom 19896
        nonmetal atom 19818
          nitrogen atom 19000
            nitrogen molecular entity 19000
              organonitrogen compound 18853
                organonitrogen heterocyclic compound 18172
                  benzimidazoles 1178
                    Omeprazole sulfide 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19898
    subatomic particle 19896
      composite particle 19896
        hadron 19896
          baryon 19896
            nucleon 19896
              atomic nucleus 19896
                atom 19896
                  main group element atom 19835
                    p-block element atom 19835
                      p-block molecular entity 19835
                        carbon group molecular entity 19774
                          organic molecular entity 19771
                            organic molecule 19724
                              organic cyclic compound 19515
                                organic heterocyclic compound 18890
                                  organic heteropolycyclic compound 18310
                                    organic heterobicyclic compound 17252
                                      benzimidazoles 1178
                                        Omeprazole sulfide 3
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