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Omeprazole sulfide - Ontology Report - Rat Genome Database

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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Omeprazole sulfide
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Accession:CHEBI:188255 term browser browse the term
Synonyms:exact_synonym: 6-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulanyl]-1H-benzimidazole
 related_synonym: Formula=C17H19N3O2S;   InChI=1S/C17H19N3O2S/c1-10-8-18-15(11(2)16(10)22-4)9-23-17-19-13-6-5-12(21-3)7-14(13)20-17/h5-8H,9H2,1-4H3,(H,19,20);   InChIKey=XURCIPRUUASYLR-UHFFFAOYSA-N;   SMILES=S(CC1=NC=C(C(OC)=C1C)C)C=2NC3=C(N2)C=CC(OC)=C3
 xref: CAS:73590-85-9;   Chemspider:137229
 xref_mesh: MESH:C040449
 xref: PDBeChem:1C6


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Omeprazole sulfide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions ISO omeprazole sulfide inhibits the reaction [Methylcholanthrene results in increased activity of AHR protein]; omeprazole sulfide inhibits the reaction [Omeprazole results in increased activity of AHR protein]; omeprazole sulfide inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]
omeprazole sulfide binds to and affects the folding of AHR protein; omeprazole sulfide binds to and results in decreased activity of AHR protein; omeprazole sulfide inhibits the reaction [Methylcholanthrene results in increased activity of AHR protein]; omeprazole sulfide inhibits the reaction [Tetrachlorodibenzodioxin affects the localization of AHR protein]; omeprazole sulfide inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]; omeprazole sulfide inhibits the reaction [Tetrachlorodibenzodioxin results in increased degradation of AHR protein]
CTD PMID:16109480 NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
ISO omeprazole sulfide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; omeprazole sulfide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]
omeprazole sulfide results in increased expression of CYP1A1 mRNA
CTD PMID:16109480 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases metabolic processing ISO CYP3A4 protein results in increased metabolism of omeprazole sulfide CTD PMID:16109480 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:9,015,383...9,285,008
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20856
    chemical entity 20854
      atom 20854
        nonmetal atom 20762
          nitrogen atom 19594
            nitrogen molecular entity 19594
              organonitrogen compound 19401
                organonitrogen heterocyclic compound 18546
                  benzimidazoles 1219
                    Omeprazole sulfide 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 20856
    subatomic particle 20854
      composite particle 20854
        hadron 20854
          baryon 20854
            nucleon 20854
              atomic nucleus 20854
                atom 20854
                  main group element atom 20777
                    p-block element atom 20777
                      p-block molecular entity 20777
                        carbon group molecular entity 20710
                          organic molecular entity 20704
                            organic molecule 20649
                              organic cyclic compound 20400
                                organic heterocyclic compound 19383
                                  organic heteropolycyclic compound 18642
                                    organic heterobicyclic compound 17527
                                      benzimidazoles 1219
                                        Omeprazole sulfide 3
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