Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Cacalol
go back to main search page
Accession:CHEBI:137832 term browser browse the term
Synonyms:related_synonym: Formula=C15H16O2;   InChI=1S/C15H16O2/c1-8-5-4-6-11-12(8)10(3)13-9(2)7-17-15(13)14(11)16/h4,6-8,16H,5H2,1-3H3/t8-/m0/s1;   InChIKey=FODSYHRFMKIVST-QMMMGPOBSA-N;   SMILES=C=1C[C@@H](C2=C(C1)C(=C3C(=C2C)C(=CO3)C)O)C
 xref: LIPID_MAPS_instance:LMPR0103300001
 xref_mesh: MESH:C497192


show annotations for term's descendants           Sort by:
Cacalol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation ISO cacalol results in decreased phosphorylation of AKT1 protein CTD PMID:20665104 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Casp3 caspase 3 increases activity ISO cacalol results in increased activity of CASP3 protein CTD PMID:20665104 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Dapk2 death-associated protein kinase 2 increases expression ISO cacalol results in increased expression of DAPK2 mRNA CTD PMID:20665104 NCBI chr 8:66,706,536...66,825,567
Ensembl chr 8:66,706,609...66,825,567 		JBrowse link
G Fas Fas cell surface death receptor multiple interactions
decreases expression		 ISO [Cyclophosphamide co-treated with cacalol] results in decreased expression of FAS protein; cacalol inhibits the reaction [Hydrogen Peroxide results in increased expression of FAS mRNA]; cacalol inhibits the reaction [SREBF1 protein binds to FAS promoter]; cacalol promotes the reaction [Paclitaxel results in decreased expression of FAS mRNA]; Paclitaxel promotes the reaction [cacalol results in decreased expression of FAS mRNA]
cacalol results in decreased expression of FAS mRNA; cacalol results in decreased expression of FAS protein		 CTD PMID:20665104 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 decreases expression
multiple interactions		 ISO cacalol results in decreased expression of SREBF1 protein
cacalol inhibits the reaction [SREBF1 protein binds to FAS promoter]		 CTD PMID:20665104 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    chemical entity 19806
      atom 19806
        nonmetal atom 19744
          carbon atom 19702
            organic molecular entity 19702
              isoprenoid 14057
                terpenoid 13755
                  sesquiterpenoid 3270
                    Cacalol 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19806
      composite particle 19806
        hadron 19806
          baryon 19806
            nucleon 19806
              atomic nucleus 19806
                atom 19806
                  main group element atom 19756
                    main group molecular entity 19756
                      s-block molecular entity 19595
                        hydrogen molecular entity 19582
                          hydrides 19095
                            organic hydride 18669
                              organic fundamental parent 18669
                                hydrocarbon 18415
                                  terpene 14057
                                    sesquiterpene 3270
                                      sesquiterpenoid 3270
                                        Cacalol 5
paths to the root