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 Gene Ontology

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Gene:
Prkcg ( Rattus norvegicus )
protein kinase C, gamma
Description:enriched in the neurons of the central nervous system and the spinal cord
Synonyms:RATPKCI; Prkcc; Protein kinase C type I (gamma type); PKCI; PKC; Protein kinase C, type I (gamma type); Prkc; MGC105487;  (details...)
ArrayIDs:6360448; 6145526; 5902626; M55417exon_s_at; 5952793; 5860821; 6248477; 6189442; 6281919; 5993397; 6643891; A_42_P774448; 6705070; 6125412; X07287cds_s_at; 5746081; 1369089_at; GE1293583; M13707_at; 5618220; 5833339; 6119241; 6529931; 6001725; 5636968; 6398576; 6188102; 6627642; 5954376; 5973050; 6526536;  (details...)
Gene Type:protein-coding
 
Additional Data
Markers: D1Arb31 D1Mgh30 D1Wox11
 
Homologs
Homo sapiens: PRKCG     See the Human gene in context in:     UCSC     NCBI MapViewer
Mus musculus: Prkcc     See the Mouse gene in context in:     UCSC     NCBI MapViewer
 
Comparative Map Data
SpeciesSymbolMap NameChr.Position
Rattus norvegicusPrkcggenome assembly 3.1164223859 - 64250823
  Rat Celera Assembly163557681 - 63584062
  RGSC genome assembly v3.4164145749 - 64172712
  Cytogenetic1q12
Mus musculusPrkccMouse genome assembly build 36.173303658 - 3331005
  Cytogenetic77 A1
Homo sapiensPRKCGhuman genome assembly1959077278 - 59102713
  Human genome assembly build 36.21959077279 - 59102713
  Cytogenetic19q13.4
 
View comparative maps:      NCBI MapViewer
 
 Genome
View:
 
Browsers:
 
Other Map Data:
Associated SSLP Map Locations
STSD1Arb31Rat cytogenetic map1
  genome assembly 3.1164223894 - 64224194
STSD1Mgh30genome assembly 3.14161141674 - 161141788
  RH 3.41735.9
  RGSC genome assembly v3.44160895153 - 160897214
STSD1Wox11RH 2.0 1473.2
  genome assembly 3.1164223922 - 64224067
  RH 3.41739.8
  RGSC genome assembly v3.4164145811 - 64145956
 
 Annotation
Molecular Function
Gene Ontology
zinc ion binding,  nucleotide binding,  calcium ion binding ...  (details...)
Biological Process
Gene Ontology
positive regulation of mismatch repair,  negative regulation of protein ubiquitination,  negative regulation of protein catabolic process ...  (details...)
Cellular Component
Gene Ontology
nucleus,  cytoplasm,  synaptosome ...  (details...)
Disease
Ontology
Retinitis Pigmentosa,  Spinocerebellar Ataxias (details...)
Expression
NoteReference
highly expressed in cerebellum, hippocampus, amygdala, and cerebral cortex633711
Pathway
Ontology
insulin signaling pathway (details...)
Transcript structure
NoteReference
promoter region lacks TATA and CAAT boxes, contains AP2, Spl, and c-myc binding sites633711
 
 External Links
Databases
DATABASEIDSOURCE
SMART:S_TKcIPI
SMART:C2IPI
SMART:S_TK_XIPI
SMART:C1IPI
PROSITE:ZF_DAG_PE_1IPI
PROSITE:PROTEIN_KINASE_DOMIPI
PROSITE:PROTEIN_KINASE_ATPIPI
PROSITE:C2IPI
PROSITE:AGC_KINASE_CTERIPI
PROSITE:ZF_DAG_PE_2IPI
PROSITE:PROTEIN_KINASE_STIPI
UNIPARC:UPI00000288CCIPI
KEGG Report:rno:24681ENTREZGENE
HomoloGene Group ID:20602ENTREZGENE
Germonline:3397
Pfam:PkinaseIPI
Pfam:C2IPI
Pfam:Pkinase_CIPI
Pfam:C1_1IPI
KEGG Pathway:04070ENTREZGENE
KEGG Pathway:04530ENTREZGENE
KEGG Pathway:04370ENTREZGENE
KEGG Pathway:04270ENTREZGENE
KEGG Pathway:04310ENTREZGENE
KEGG Pathway:05200ENTREZGENE
KEGG Pathway:04730ENTREZGENE
KEGG Pathway:04720ENTREZGENE
KEGG Pathway:04010ENTREZGENE
KEGG Pathway:04916ENTREZGENE
KEGG Pathway:04650ENTREZGENE
KEGG Pathway:04020ENTREZGENE
KEGG Pathway:05223ENTREZGENE
KEGG Pathway:04012ENTREZGENE
KEGG Pathway:04670ENTREZGENE
KEGG Pathway:05214ENTREZGENE
KEGG Pathway:04540ENTREZGENE
KEGG Pathway:04510ENTREZGENE
KEGG Pathway:04666ENTREZGENE
KEGG Pathway:04664ENTREZGENE
InterPro:Pkinase_C.IPI
InterPro:PKC.IPI
InterPro:Kinase-like_dom.IPI
InterPro:DAG/PE_bd.IPI
InterPro:C2_region.IPI
InterPro:C2_membr_targeting.IPI
InterPro:C2_Ca/lipid-bd_reg_CaLB.IPI
InterPro:C2_Ca-dep.IPI
InterPro:AGC-kinase_C.IPI
InterPro:Prot_kinase_cat_dom.IPI
InterPro:Prot_Kinase_C-like_PE/DAG_bd.IPI
InterPro:Protein_kinase_ATP_BS.IPI
InterPro:Protein_kinase_C_a/b/g.IPI
InterPro:Ser/Thr_prot_kinase_dom.IPI
InterPro:Ser/Thr_prot_kinase_AS.IPI
InterPro:Se/Thr_prot_kinase-like_dom.IPI
Ensembl Protein:ENSRNOP00000019825IPI
IPI:IPI00201797IPI
Entrez Gene:PrkcgENTREZGENE
PIRSF:PKC_alphaIPI
IMAGE_CLONE:IMAGE:7319243IMAGE-MGC_LOAD
MGC_CLONE:MGC:105487IMAGE-MGC_LOAD
Ensembl Genes:ENSRNOG00000014688IPI
TIGR:TC231291
UniProt:KPCG_RATIPI
Superfamily-SCOP:C2_CaLBIPI
Superfamily-SCOP:Kinase_likeIPI
RatMap:34326ENTREZGENE
PANTHER:PKCIPI
PRINTS:DAGPEDOMAIN.IPI
PRINTS:C2DOMAIN.IPI
Sequences
Nucleotide:BC089226Get FASTASearch GEO Profiles
Nucleotide:M55417Get FASTASearch GEO Profiles
Nucleotide:M13707Get FASTASearch GEO Profiles
Nucleotide:CH474101Get FASTASearch GEO Profiles
Nucleotide:X07287Get FASTASearch GEO Profiles
Nucleotide:NM_012628Get FASTASearch GEO Profiles
(View all 6 Nucleotide Accessions)
Protein:NP_036760Get FASTA
Protein:CAA30267Get FASTA
Protein:AAA41873Get FASTA
Protein:AAA41874Get FASTA
Protein:EDL84948Get FASTA
Protein:AAH89226Get FASTA
Protein:P63319Get FASTA
(View all 7 Protein Accessions)
Clusters
UniGene:9747
 
 References
Curated References
13 references in RGD related to Prkcg
Other References
33 other references at PubMed related to Prkcg
 
 Database Information
RGD ID3397
History
Date Current Symbol Current Name Previous Symbol Previous name Status Description Reference
24-OCT-08: Prkcg protein kinase C, gamma Prkcc protein kinase C, gamma APPROVED Nomenclature updated to reflect human and mouse nomenclature 1299863
09-APR-03: Prkcc protein kinase C, gamma Prkcg Protein kinase C, type I (gamma type) APPROVED Symbol and Name updated 629477
10-JUN-02: Prkcg Protein kinase C, type I (gamma type) APPROVED Symbol and Name status set to approved 70586

       

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