Gene:	Nras ( Rattus norvegicus ) neuroblastoma ras oncogene
Description:	a GTPase; involved in GTPase mediated signal transduction, may play a role in collagen-induced arthritis in rats
Synonyms:	neuroblastoma RAS viral (v-ras) oncogene homolog;  (details...)
ArrayIDs:	rc_AA818512_at; 1387678_at; A_44_P399146; 5984881; rc_AA943331_s_at; 6394500; 6648173; 6697310; 6428506; 5972254; 5746793; 6700782; 6729172; 6309053; X68394_at; 5658831; 5712406; 6349133; 1372032_at; 5852602; A_43_P15591; 5705913; 6231925;  (details...)
Gene Type:	protein-coding
Additional Data
Candidate gene for:	Cia10 - Collagen induced arthritis QTL 10
Curated Variants:	Nras-ps1
Homologs
Homo sapiens: NRAS     See the Human gene in context in:     UCSC     NCBI MapViewer
Mus musculus: Nras     See the Mouse gene in context in:     UCSC     NCBI MapViewer
Comparative Map Data Species Symbol Map Name Chr. Position Rattus norvegicus Nras genome assembly 3.1 2 198255369 - 198265062     Rat Celera Assembly 2 183056270 - 183065962     RGSC genome assembly v3.4 2 198292616 - 198302308     Cytogenetic 2 q34 Mus musculus Nras Mouse genome assembly build 36.1 3 102862208 - 102871837     Cytogenetic 3 3 F2.2 Homo sapiens NRAS human genome assembly 1 114961626 - 114971557     Human genome assembly build 36.2 1 115051108 - 115061038     Cytogenetic 1 p13.2   View comparative maps:      NCBI MapViewer
Genome
View:
Browsers:	Select a browser to viewGene (GBrowse)Gene and SNPs (GBrowse)UCSCVCMAPEnsemblNCBIECRVISTAVISTA+UCSC
Annotation
Molecular Function	Gene Ontology GTP binding,  protein binding,  nucleotide binding ...  (details...)
Biological Process	Gene Ontology regulation of long-term neuronal synaptic plasticity,  endocytosis,  small GTPase mediated signal transduction ...  (details...)
Cellular Component	Gene Ontology intracellular,  anchored to membrane,  plasma membrane ...  (details...)
Disease	Note Reference involved in the severity of collagen-induced arthritis 61063 Ontology Sarcoma, Experimental,  Mouth Neoplasms,  Arthritis, Experimental (details...)
Phenotype	Ontology fibrosarcoma (details...)
External Links
Databases	DATABASE ID SOURCE SMART: RAS IPI PROSITE: RAS IPI UNIPARC: UPI000013313F IPI KEGG Report: rno:24605 ENTREZGENE HomoloGene Group ID: 55661 ENTREZGENE Germonline: 3205 Pfam: Ras IPI KEGG Pathway: 04010 ENTREZGENE KEGG Pathway: 04720 ENTREZGENE KEGG Pathway: 04730 ENTREZGENE KEGG Pathway: 04910 ENTREZGENE KEGG Pathway: 04912 ENTREZGENE KEGG Pathway: 05214 ENTREZGENE KEGG Pathway: 04540 ENTREZGENE KEGG Pathway: 04664 ENTREZGENE KEGG Pathway: 04012 ENTREZGENE KEGG Pathway: 05213 ENTREZGENE KEGG Pathway: 05220 ENTREZGENE KEGG Pathway: 04062 ENTREZGENE KEGG Pathway: 05219 ENTREZGENE KEGG Pathway: 04662 ENTREZGENE KEGG Pathway: 04360 ENTREZGENE KEGG Pathway: 05221 ENTREZGENE KEGG Pathway: 04370 ENTREZGENE KEGG Pathway: 04530 ENTREZGENE KEGG Pathway: 05216 ENTREZGENE KEGG Pathway: 04660 ENTREZGENE KEGG Pathway: 05211 ENTREZGENE KEGG Pathway: 04810 ENTREZGENE KEGG Pathway: 05215 ENTREZGENE KEGG Pathway: 05200 ENTREZGENE KEGG Pathway: 05223 ENTREZGENE KEGG Pathway: 04722 ENTREZGENE KEGG Pathway: 04650 ENTREZGENE KEGG Pathway: 05218 ENTREZGENE KEGG Pathway: 04916 ENTREZGENE InterPro: Small_GTP_bd. IPI InterPro: Ras_small_GTPase. IPI InterPro: Ras_Ras_related. IPI InterPro: Ras_GTPase. IPI InterPro: Ras. IPI InterPro: GTPase_Ras. IPI Ensembl Protein: ENSRNOP00000036381 IPI IPI: IPI00190869 IPI Entrez Gene: Nras ENTREZGENE IMAGE_CLONE: IMAGE:7368145 IMAGE-MGC_LOAD MGC_CLONE: MGC:112605 IMAGE-MGC_LOAD UniProt: RASN_RAT IPI Ensembl Genes: ENSRNOG00000023079 IPI RatMap: 34241 ENTREZGENE PANTHER: Ras_Ras_related IPI TIGRFAMs: small_GTP IPI PRINTS: RASTRNSFRMNG. IPI
Sequences	Nucleotide: BC098659 Get FASTA Search GEO Profiles Nucleotide: X68394 Get FASTA Search GEO Profiles Nucleotide: S69393 Get FASTA Search GEO Profiles Nucleotide: CH474015 Get FASTA Search GEO Profiles Nucleotide: NM_080766 Get FASTA Search GEO Profiles (View all 5 Nucleotide Accessions) Protein: Q04970 Get FASTA Protein: AAH98659 Get FASTA Protein: CAA48460 Get FASTA Protein: AAC60676 Get FASTA Protein: EDL85498 Get FASTA Protein: NP_542944 Get FASTA (View all 6 Protein Accessions)
Clusters	UniGene: 217722
References
Curated References	12 references in RGD related to Nras
Other References	14 other references at PubMed related to Nras
Database Information
RGD ID	3205
History	Date Current Symbol Current Name Previous Symbol Previous name Status Description Reference 17-NOV-05: Nras neuroblastoma ras oncogene APPROVED Name updated 1299863 06-NOV-02: Nras neuroblastoma RAS viral (v-ras) oncogene homolog Neuroblastoma RAS viral (v-ras) oncogene homolog APPROVED Name updated 625702 10-JUN-02: Nras Neuroblastoma RAS viral (v-ras) oncogene homolog APPROVED Symbol and Name status set to approved 70586