Chrnb2 (cholinergic receptor nicotinic beta 2 subunit) - Rat Genome Database

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Gene: Chrnb2 (cholinergic receptor nicotinic beta 2 subunit) Rattus norvegicus
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Symbol: Chrnb2
Name: cholinergic receptor nicotinic beta 2 subunit
RGD ID: 2350
Description: Enables acetylcholine binding activity; acetylcholine-gated monoatomic cation-selective channel activity; and quaternary ammonium group binding activity. Contributes to heterocyclic compound binding activity. Involved in acetylcholine receptor signaling pathway; cholinergic synaptic transmission; and response to nicotine. Located in plasma membrane raft. Part of acetylcholine-gated channel complex. Is active in cholinergic synapse; postsynaptic specialization membrane; and presynaptic membrane. Human ortholog(s) of this gene implicated in autosomal dominant nocturnal frontal lobe epilepsy and autosomal dominant nocturnal frontal lobe epilepsy 3. Orthologous to human CHRNB2 (cholinergic receptor nicotinic beta 2 subunit); PARTICIPATES IN acetylcholine signaling pathway via nicotinic acetylcholine receptor; alfentanil pharmacodynamics pathway; bupivacaine pharmacodynamics pathway; INTERACTS WITH (E)-thiamethoxam; (S)-anabasine; (S)-nicotine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: cholinergic receptor nicotinic beta polypeptide 2; cholinergic receptor nicotinic beta subunit 2; cholinergic receptor, nicotinic beta 2; cholinergic receptor, nicotinic, beta 2 (neuronal); cholinergic receptor, nicotinic, beta polypeptide 2; cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal); cholinergic receptor, nicotinic, beta subunit 2; N-alpha 1; neuronal acetylcholine receptor non-alpha-1 chain; neuronal acetylcholine receptor subunit beta-2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82177,479,091 - 177,487,306 (-)NCBIGRCr8
mRatBN7.22175,181,402 - 175,189,619 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2175,181,402 - 175,189,619 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2182,330,071 - 182,338,257 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02180,352,453 - 180,360,643 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02174,953,345 - 174,961,538 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02189,088,570 - 189,096,785 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2189,088,570 - 189,096,785 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02208,511,421 - 208,519,636 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42181,961,373 - 181,969,581 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12181,911,478 - 181,919,687 (-)NCBI
Celera2169,123,949 - 169,132,124 (-)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-lobeline  (ISO)
(E)-thiamethoxam  (EXP)
(S)-anabasine  (EXP)
(S)-nicotine  (EXP,ISO)
1,1-dimethyl-4-phenylpiperazinium iodide  (EXP,ISO)
13-desmethylspirolide C  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
2,2',4,4'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4-nonylphenol  (ISO)
4-octylphenol  (ISO)
acetamiprid  (EXP,ISO)
acetylcholine  (EXP,ISO)
alcuronium  (ISO)
all-trans-retinoic acid  (ISO)
aluminium hydroxide  (ISO)
Amaranth  (EXP)
amitriptyline  (EXP,ISO)
ammonium chloride  (EXP)
Antimony trioxide  (ISO)
antimycin A  (ISO)
atracurium  (ISO)
atropine  (EXP,ISO)
barium(0)  (EXP)
bentonite  (ISO)
benzo[a]pyrene  (EXP,ISO)
bisphenol A  (EXP,ISO)
bleomycin A2  (EXP)
Brilliant Blue  (EXP)
butan-1-ol  (ISO)
calcium atom  (EXP,ISO)
calcium(0)  (EXP,ISO)
carbachol  (EXP,ISO)
carbamazepine  (ISO)
carbaryl  (EXP)
chlorpyrifos  (EXP)
choline  (ISO)
cisatracurium  (ISO)
Citreoviridin  (ISO)
clofibrate  (ISO)
clothianidin  (EXP,ISO)
cocaine  (EXP,ISO)
cyclosporin A  (ISO)
cytisine  (EXP,ISO)
decabromodiphenyl ether  (ISO)
decamethonium  (ISO)
deguelin  (ISO)
Desformylflustrabromine  (ISO)
diazinon  (EXP)
dichloroacetic acid  (ISO)
dichlorvos  (ISO)
diethylstilbestrol  (ISO)
dihydro-beta-erythroidine  (EXP,ISO)
dinotefuran  (EXP)
dopamine  (ISO)
endosulfan  (EXP)
epibatidine  (EXP,ISO)
EPTC  (EXP)
ethanol  (EXP,ISO)
fenoxycarb  (EXP)
folic acid  (ISO)
furan  (EXP)
galanthamine  (ISO)
galanthamine Trifluoroacetic acid  (ISO)
genistein  (EXP)
gentamycin  (EXP)
graphite  (EXP)
hexachlorophene  (EXP,ISO)
Hexamethonium  (ISO)
imidacloprid  (EXP,ISO)
indigo carmine  (EXP)
lead diacetate  (EXP)
LY294002  (ISO)
magnesium dihydroxide  (ISO)
Mecamylamine  (EXP,ISO)
mercury dichloride  (EXP)
methyllycaconitine  (EXP,ISO)
Mivacurium  (ISO)
nicotine  (EXP,ISO)
nitenpyram  (EXP)
ochratoxin A  (EXP)
okadaic acid  (ISO)
pancuronium  (ISO)
paracetamol  (ISO)
paraoxon  (EXP)
paraquat  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
PhIP  (EXP)
physostigmine  (ISO)
progesterone  (ISO)
pyrazines  (ISO)
pyridines  (ISO)
rivastigmine  (ISO)
rocuronium  (ISO)
scopolamine  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (ISO)
sterigmatocystin  (EXP)
succinylcholine  (ISO)
Sunset Yellow FCF  (EXP)
T-2 toxin  (ISO)
tacrine  (ISO)
tamoxifen  (ISO)
tartrazine  (EXP)
tetrachloroethene  (EXP,ISO)
tetrachloromethane  (EXP)
thiacloprid  (EXP)
thiamethoxam  (EXP)
toluene  (EXP,ISO)
trichloroethene  (EXP)
triphenyl phosphate  (ISO)
triptonide  (ISO)
tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate  (EXP,ISO)
tubocurarine  (EXP,ISO)
urethane  (EXP)
valproic acid  (EXP,ISO)
varenicline  (EXP,ISO)
vecuronium bromide  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
acetylcholine receptor signaling pathway  (IBA,IGI,ISO)
action potential  (ISO)
associative learning  (ISO)
B cell activation  (ISO)
B cell proliferation  (ISO)
behavioral response to nicotine  (ISO)
calcium ion transport  (ISO)
central nervous system neuron axonogenesis  (ISO)
central nervous system projection neuron axonogenesis  (ISO)
cognition  (ISO)
conditioned taste aversion  (ISO)
dopamine secretion  (ISO)
establishment of localization in cell  (ISO)
excitatory postsynaptic potential  (IEA)
lateral geniculate nucleus development  (ISO)
learning  (ISO)
locomotory behavior  (ISO)
membrane depolarization  (IBA,ISO)
memory  (ISO)
monoatomic ion transmembrane transport  (IEA)
negative regulation of neuronal action potential  (ISO)
nervous system process  (ISO)
neuronal action potential  (ISO)
optic nerve morphogenesis  (ISO)
positive regulation of B cell proliferation  (ISO)
positive regulation of dopamine secretion  (ISO)
positive regulation of synaptic transmission, dopaminergic  (ISO)
presynaptic modulation of chemical synaptic transmission  (ISO)
regulation of circadian sleep/wake cycle, non-REM sleep  (ISO)
regulation of circadian sleep/wake cycle, REM sleep  (ISO)
regulation of dendrite morphogenesis  (ISO)
regulation of dopamine metabolic process  (ISO)
regulation of dopamine secretion  (ISO)
regulation of membrane potential  (ISO)
regulation of synapse assembly  (ISO)
regulation of synaptic transmission, dopaminergic  (ISO)
response to acetylcholine  (IDA,IGI)
response to cocaine  (ISO)
response to ethanol  (ISO)
response to hypoxia  (ISO)
response to nicotine  (IMP,ISO)
sensory perception of pain  (ISO)
sensory perception of sound  (ISO)
signal transduction  (ISO)
smooth muscle contraction  (ISO)
social behavior  (ISO)
synaptic transmission involved in micturition  (ISO)
synaptic transmission, cholinergic  (IMP)
vestibulocochlear nerve development  (ISO)
visual learning  (ISO)
visual perception  (ISO)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
acetylcholine signaling pathway via nicotinic acetylcholine receptor  (ISO)
alfentanil pharmacodynamics pathway  (ISO)
bupivacaine pharmacodynamics pathway  (ISO)
buprenorphine pharmacodynamics pathway  (ISO)
chloroprocaine pharmacodynamics pathway  (ISO)
citalopram pharmacodynamics pathway  (ISO)
cocaine pharmacodynamics pathway  (ISO)
codeine and morphine pharmacodynamics pathway  (ISO)
desipramine pharmacodynamics pathway  (ISO)
diphenoxylate pharmacodynamics pathway  (ISO)
escitalopram pharmacodynamics pathway  (ISO)
ethylmorphine pharmacodynamics pathway  (ISO)
fentanyl pharmacodynamics pathway  (ISO)
fluoxetine pharmacodynamics pathway  (ISO)
heroin pharmacodynamics pathway  (ISO)
hydrocodone pharmacodynamics pathway  (ISO)
hydromorphone pharmacodynamics pathway  (ISO)
imipramine pharmacodynamics pathway  (ISO)
levacetylmethadol pharmacodynamics pathway  (ISO)
levobupivacaine phgarmacodynamics pathway  (ISO)
levorphanol pharmacodynamics pathway  (ISO)
lidocaine pharmacodynamics pathway  (ISO)
mepivacaine pharmacodynamics pathway  (ISO)
methadone pharmacodynamics pathway  (ISO)
nalbuphine pharmacodynamics pathway  (ISO)
naloxone pharmacodynamics pathway  (ISO)
naltrexone pharmacodynamics pathway  (ISO)
nicotine pharmacodynamics pathway  (ISO)
nicotine pharmacokinetics pathway  (ISO)
oxybuprocaine pharmacodynamics pathway  (ISO)
oxycodone pharmacodynamics pathway  (ISO)
oxymorphone pharmacodynamics pathway  (ISO)
pentazocine pharmacodynamics pathway  (ISO)
prilocaine pharmacodynamics pathway  (ISO)
procaine pharmacodynamics pathway  (ISO)
remifentanil pharmacodynamics pathway  (ISO)
ropivacaine pharmacodynamics pathway  (ISO)
tramadol pharmacodynamics pathway  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Mammalian nicotinic acetylcholine receptors: from structure to function. Albuquerque EX, etal., Physiol Rev. 2009 Jan;89(1):73-120. doi: 10.1152/physrev.00015.2008.
2. Varenicline is a potent partial agonist at alpha6beta2* nicotinic acetylcholine receptors in rat and monkey striatum. Bordia T, etal., J Pharmacol Exp Ther. 2012 Aug;342(2):327-34. doi: 10.1124/jpet.112.194852. Epub 2012 May 1.
3. Functional expression of two neuronal nicotinic acetylcholine receptors from cDNA clones identifies a gene family. Boulter J, etal., Proc Natl Acad Sci U S A 1987 Nov;84(21):7763-7.
4. The a7 nicotinic acetylcholine receptor function in hippocampal neurons is regulated by the lipid composition of the plasma membrane. Colón-Sáez JO and Yakel JL, J Physiol. 2011 Jul 1;589(Pt 13):3163-74. doi: 10.1113/jphysiol.2011.209494. Epub 2011 May 3.
5. Primary structure and expression of beta 2: a novel subunit of neuronal nicotinic acetylcholine receptors. Deneris ES, etal., Neuron 1988 Mar;1(1):45-54.
6. Molecular biology and electrophysiology of neuronal nicotinic receptors of rat chromaffin cells. Di Angelantonio S, etal., Eur J Neurosci 2003 Jun;17(11):2313-22.
7. Formation of oligomers containing the beta3 and beta4 subunits of the rat nicotinic receptor. Forsayeth JR and Kobrin E, J Neurosci. 1997 Mar 1;17(5):1531-8.
8. Nicotinic receptor subunit alpha5 modifies assembly, up-regulation, and response to pro-inflammatory cytokines. Gahring LC and Rogers SW, J Biol Chem. 2010 Aug 20;285(34):26049-57. doi: 10.1074/jbc.M110.105346. Epub 2010 Jun 21.
9. Subsynaptic localization of nicotinic acetylcholine receptor subunits: a comparative study in the mouse and rat striatum. Garção P, etal., Neurosci Lett. 2014 Apr 30;566:106-10. doi: 10.1016/j.neulet.2014.02.018. Epub 2014 Mar 4.
10. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
11. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
12. Rat nicotinic ACh receptor alpha7 and beta2 subunits co-assemble to form functional heteromeric nicotinic receptor channels. Khiroug SS, etal., J Physiol 2002 Apr 15;540(Pt 2):425-34.
13. A novel nicotinic acetylcholine receptor subtype in basal forebrain cholinergic neurons with high sensitivity to amyloid peptides. Liu Q, etal., J Neurosci. 2009 Jan 28;29(4):918-29. doi: 10.1523/JNEUROSCI.3952-08.2009.
14. Quantitative analysis of the heteromeric neuronal nicotinic receptors in the rat hippocampus. Lomazzo E, etal., J Neurochem. 2010 Nov;115(3):625-34. doi: 10.1111/j.1471-4159.2010.06967.x. Epub 2010 Sep 27.
15. The ultrastructural distribution of putative nicotinic receptors on cultured neurons from the rat superior cervical ganglion. Loring RH, etal., Neuroscience. 1988 Mar;24(3):1071-80.
16. Nicotinic cholinergic receptors in the rat retina: simple and mixed heteromeric subtypes. Marritt AM, etal., Mol Pharmacol. 2005 Dec;68(6):1656-68. Epub 2005 Aug 29.
17. Postsynaptic alpha 4 beta 2 and alpha 7 type nicotinic acetylcholine receptors contribute to the local and endogenous acetylcholine-mediated synaptic transmissions in nigral dopaminergic neurons. Matsubayashi H, etal., Brain Res. 2004 Apr 16;1005(1-2):1-8.
18. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
19. Modulation of neuronal nicotinic acetylcholine receptors by halothane in rat cortical neurons. Mori T, etal., Mol Pharmacol. 2001 Apr;59(4):732-43.
20. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
21. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
22. Online Mendelian Inheritance in Man, OMIM (TM). Online Mendelian Inheritance in Man, OMIM (TM).
23. Nicotinic acetylcholine receptor alpha 7 regulates cAMP signal within lipid rafts. Oshikawa J, etal., Am J Physiol Cell Physiol. 2003 Sep;285(3):C567-74. Epub 2003 May 14.
24. CHRNB2 is the second acetylcholine receptor subunit associated with autosomal dominant nocturnal frontal lobe epilepsy. Phillips HA, etal., Am J Hum Genet 2001 Jan;68(1):225-31. Epub 2000 Dec 5.
25. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
26. UBXD4, a UBX-containing protein, regulates the cell surface number and stability of alpha3-containing nicotinic acetylcholine receptors. Rezvani K, etal., J Neurosci. 2009 May 27;29(21):6883-96. doi: 10.1523/JNEUROSCI.4723-08.2009.
27. GOA pipeline RGD automated data pipeline
28. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
29. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
30. Five ADNFLE mutations reduce the Ca2+ dependence of the mammalian alpha4beta2 acetylcholine response. Rodrigues-Pinguet N, etal., J Physiol 2003 Jul 1;550(Pt 1):11-26. Epub 2003 May 16.
31. An extracellular protein microdomain controls up-regulation of neuronal nicotinic acetylcholine receptors by nicotine. Sallette J, etal., J Biol Chem 2004 Apr 30;279(18):18767-75. Epub 2004 Feb 5.
32. The comparative pharmacology and up-regulation of rat neuronal nicotinic receptor subtype binding sites stably expressed in transfected mammalian cells. Xiao Y and Kellar KJ, J Pharmacol Exp Ther. 2004 Jul;310(1):98-107. Epub 2004 Mar 11.
33. Increased neurodegeneration during ageing in mice lacking high-affinity nicotine receptors. Zoli M, etal., EMBO J 1999 Mar 1;18(5):1235-44.
Additional References at PubMed
PMID:7870173   PMID:8906617   PMID:9428762   PMID:9614223   PMID:10235262   PMID:10531434   PMID:11027228   PMID:11044747   PMID:11145999   PMID:11222635   PMID:11282258   PMID:11344259  
PMID:11955523   PMID:12079404   PMID:12097474   PMID:12189247   PMID:12876201   PMID:12944511   PMID:14687550   PMID:15215293   PMID:15450117   PMID:15456819   PMID:15464132   PMID:15469877  
PMID:15489024   PMID:15541879   PMID:15569257   PMID:15608630   PMID:15741168   PMID:15788760   PMID:15929983   PMID:15955596   PMID:15963492   PMID:15964197   PMID:16014729   PMID:16033901  
PMID:16253349   PMID:16407231   PMID:16772172   PMID:16965547   PMID:17192655   PMID:17301182   PMID:17470777   PMID:17559419   PMID:17626178   PMID:17900292   PMID:18387948   PMID:18583454  
PMID:18602971   PMID:18818999   PMID:19095841   PMID:19187266   PMID:19567877   PMID:20238211   PMID:20616056   PMID:20633015   PMID:22064677   PMID:22253754   PMID:22323734   PMID:23056257  
PMID:23219030   PMID:23429044   PMID:23583932   PMID:23734673   PMID:23811311   PMID:23846688   PMID:24398291   PMID:25713061   PMID:26276394   PMID:26858154   PMID:27721068   PMID:28666811  


Genomics

Comparative Map Data
Chrnb2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82177,479,091 - 177,487,306 (-)NCBIGRCr8
mRatBN7.22175,181,402 - 175,189,619 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2175,181,402 - 175,189,619 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2182,330,071 - 182,338,257 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02180,352,453 - 180,360,643 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02174,953,345 - 174,961,538 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02189,088,570 - 189,096,785 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2189,088,570 - 189,096,785 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02208,511,421 - 208,519,636 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42181,961,373 - 181,969,581 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12181,911,478 - 181,919,687 (-)NCBI
Celera2169,123,949 - 169,132,124 (-)NCBICelera
Cytogenetic Map2q34NCBI
CHRNB2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381154,567,778 - 154,580,013 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1154,567,778 - 154,580,013 (+)EnsemblGRCh38hg38GRCh38
GRCh371154,540,254 - 154,552,489 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361152,806,881 - 152,818,978 (+)NCBINCBI36Build 36hg18NCBI36
Build 341151,353,329 - 151,362,156NCBI
Celera1127,611,891 - 127,623,988 (+)NCBICelera
Cytogenetic Map1q21.3NCBI
HuRef1125,903,718 - 125,915,813 (+)NCBIHuRef
CHM1_11155,936,657 - 155,948,754 (+)NCBICHM1_1
T2T-CHM13v2.01153,704,898 - 153,719,720 (+)NCBIT2T-CHM13v2.0
Chrnb2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39389,660,755 - 89,671,939 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl389,653,502 - 89,671,939 (-)EnsemblGRCm39 Ensembl
GRCm38389,753,448 - 89,764,632 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl389,746,195 - 89,764,632 (-)EnsemblGRCm38mm10GRCm38
MGSCv37389,557,370 - 89,568,554 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36389,839,375 - 89,850,512 (-)NCBIMGSCv36mm8
Celera389,790,490 - 89,801,674 (-)NCBICelera
Cytogenetic Map3F1NCBI
cM Map339.19NCBI
Chrnb2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555451,065,457 - 1,077,526 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555451,065,457 - 1,077,056 (+)NCBIChiLan1.0ChiLan1.0
CHRNB2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2195,254,104 - 95,266,251 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1194,986,423 - 94,998,575 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01129,922,740 - 129,931,582 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11133,535,023 - 133,547,361 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1133,535,023 - 133,547,361 (+)Ensemblpanpan1.1panPan2
CHRNB2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1742,786,505 - 42,797,976 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl742,789,600 - 42,795,722 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha742,277,266 - 42,288,752 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0742,656,510 - 42,668,001 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl742,656,517 - 42,667,042 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1742,435,765 - 42,447,248 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0742,489,629 - 42,501,090 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0742,773,221 - 42,784,709 (-)NCBIUU_Cfam_GSD_1.0
Chrnb2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505825,136,236 - 25,149,726 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365804,166,619 - 4,186,443 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365804,165,255 - 4,179,285 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CHRNB2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl495,198,717 - 95,211,037 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1495,196,992 - 95,211,084 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24104,024,711 - 104,036,882 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CHRNB2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1209,245,803 - 9,255,430 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl209,247,231 - 9,253,795 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660388,581,863 - 8,595,204 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Chrnb2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248852,843,899 - 2,848,522 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248852,839,607 - 2,851,934 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Chrnb2
47 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:91
Count of miRNA genes:68
Interacting mature miRNAs:81
Transcripts:ENSRNOT00000028200
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61374Edpm2Estrogen-dependent pituitary mass QTL 24.420.86pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)276539322202447032Rat
61401Niddm2Non-insulin dependent diabetes mellitus QTL 24.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2144599348189599348Rat
1598805Memor8Memory QTL 83exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)2150341585189039377Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)2135552573202446871Rat
71113Cari2Carrageenan-induced inflammation QTL 22.70.009hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)2141596551202447032Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)246123260202447032Rat
61457Niddm8Non-insulin dependent diabetes mellitus QTL 84.10.01blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)2174543008175950118Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)243154682202446871Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)243154682202446871Rat
61469Bp16Blood pressure QTL 165.64arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)2169745596214745596Rat
61473Bp19Blood pressure QTL 196.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2172710921175950118Rat
70162Bp63Blood pressure QTL 635.64arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)2169745596214745596Rat
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)278665619249053267Rat
724568Uae13Urinary albumin excretion QTL 134.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)2143157029210020885Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
1298076Bp166Blood pressure QTL 1660.0009arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2136445150202447032Rat
1298080Bp163Blood pressure QTL 1630.02arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118275202447032Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
631501Bp101Blood pressure QTL 1012.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2150341684202446871Rat
631507Bp105Blood pressure QTL 1050.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2112456140212696837Rat
631522Bp74Blood pressure QTL 740.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2172710921184114403Rat
634308Sach6Saccharin preference QTL 64.9taste sensitivity trait (VT:0001986)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)2112456140212696837Rat
1358356Srcrt1Stress Responsive Cort QTL13.66blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)2161699179222436696Rat
1300165Rf9Renal function QTL 93.28kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)2133914684202447032Rat
1331734Bp204Blood pressure QTL 2043.61192arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2168358098223265385Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)256043031202447032Rat
1331794Bp202Blood pressure QTL 2023.66819arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2141194931223265385Rat
1331805Cm29Cardiac mass QTL 293.50746heart mass (VT:0007028)heart wet weight (CMO:0000069)2141194931223265385Rat
1302793Bw16Body weight QTL 1650.0001body mass (VT:0001259)body weight (CMO:0000012)2157142209202446871Rat
1354601Slep1Serum leptin concentration QTL 15.39blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)243171017184114403Rat
1354605Rf48Renal function QTL 482.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)274786664206665859Rat
1354609Niddm62Non-insulin dependent diabetes mellitus QTL 624.720.000006insulin secretion trait (VT:0003564)plasma insulin level (CMO:0000342)2150540301202447032Rat
1354622Kidm16Kidney mass QTL 163kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)281754530222436696Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118463226797303Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)281754530227146641Rat
1359022Ppulsi1Prepulse inhibition QTL 13.63prepulse inhibition trait (VT:0003088)acoustic startle response measurement (CMO:0001519)2136916935213594495Rat
1549833Bp257Blood pressure QTL 2570.003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2168354880185122374Rat
1554319Bmd2Bone mineral density QTL 213.40.0001lumbar vertebra area (VT:0010570)lumbar vertebra cross-sectional area (CMO:0001689)2114837675212549332Rat
1358900Bw48Body weight QTL 484.88body mass (VT:0001259)body weight (CMO:0000012)2157142078211086598Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
1359030Bp277Blood pressure QTL 277arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2114837527185876470Rat
1359030Bp277Blood pressure QTL 277arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2114837527185876470Rat
1359032Hrtrt18Heart rate QTL 18heart pumping trait (VT:2000009)heart rate (CMO:0000002)2157142078192625452Rat
1581502Esta3Estrogen-induced thymic atrophy QTL 3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)2136916935189599348Rat
1641891Alcrsp17Alcohol response QTL 17response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561249053267Rat
1641925Alcrsp2Alcohol response QTL 2response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561221167075Rat
1581569Uae32Urinary albumin excretion QTL 320.0001urine protein amount (VT:0005160)urine albumin excretion rate (CMO:0000757)278665619219826953Rat
1598833Bp295Blood pressure QTL 2953.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2147798556192798556Rat
1598838Bp290Blood pressure QTL 2901.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2166539266211539266Rat
1578648Bss11Bone structure and strength QTL 114.7femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)2114837527211674221Rat
2293084Iddm26Insulin dependent diabetes mellitus QTL 262.9blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2174930955213594495Rat
2293843Kiddil6Kidney dilation QTL 63.1kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)242804607182042367Rat
2301415Cm67Cardiac mass QTL 670.003heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)2152413072175950118Rat
2301966Bp322Blood pressure QTL 3223.58arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2150540301202447032Rat
2306901Bp337Blood pressure QTL 3370.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2164073756227146641Rat
2307174Activ3Activity QTL 34.830.000058locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)2168594495213594495Rat
6903312Bw112Body weight QTL 1123.20.0013body mass (VT:0001259)body weight (CMO:0000012)2143657569184114274Rat
7488904Bp363Blood pressure QTL 3630.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2172982062175950118Rat
7488925Bp364Blood pressure QTL 3640.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2160564068205564068Rat
7488927Bp365Blood pressure QTL 3650.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2162765032207765032Rat
8662843Vetf9Vascular elastic tissue fragility QTL 92.05thoracic aorta molecular composition trait (VT:0010568)aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)2157142078226277316Rat
8662832Vetf7Vascular elastic tissue fragility QTL 73.5aorta elastin amount (VT:0003905)aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)281689826221035911Rat
10043136Iddm54Insulin dependent diabetes mellitus QTL 543.40.0001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2143657411190602963Rat
10043136Iddm54Insulin dependent diabetes mellitus QTL 543.40.0001blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)2143657411190602963Rat
12879836Kidm61Kidney mass QTL 610.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2152413072185122374Rat
12879837Am2Aortic mass QTL 20.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)2152413072185122374Rat
12879838Cm86Cardiac mass QTL 860.002heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)2152413072185122374Rat
12879839Cm85Cardiac mass QTL 850.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)2152413072185122374Rat
12879840Bw179Body weight QTL 1790.005body mass (VT:0001259)body weight (CMO:0000012)2152413072185122374Rat
12879845Cm89Cardiac mass QTL 890.008heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)2152413072175950118Rat
12879846Cm90Cardiac mass QTL 900.011heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)2152413072175950118Rat
12879847Am4Aortic mass QTL 40.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)2152413072175950118Rat
11565180Kidm56Kidney mass QTL 560.003kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2152413072175950118Rat
11565181Bw176Body weight QTL 1760.002body mass (VT:0001259)body weight (CMO:0000012)2152413072175950118Rat

Markers in Region
BF388105  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22175,181,080 - 175,181,261 (+)MAPPERmRatBN7.2
Rnor_6.02189,088,249 - 189,088,429NCBIRnor6.0
Rnor_5.02208,511,100 - 208,511,280UniSTSRnor5.0
RGSC_v3.42181,961,052 - 181,961,232UniSTSRGSC3.4
Celera2169,123,628 - 169,123,808UniSTS
RH 3.4 Map21155.4UniSTS
Cytogenetic Map2q34UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 68
Low 1 6 10 2 2 6 8 28 2
Below cutoff 2 33 24 16 17 16 5 6 27 13 9 5

Sequence


RefSeq Acc Id: ENSRNOT00000028200   ⟹   ENSRNOP00000028200
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2175,181,402 - 175,189,619 (-)Ensembl
Rnor_6.0 Ensembl2189,088,570 - 189,096,785 (-)Ensembl
RefSeq Acc Id: NM_019297   ⟹   NP_062170
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82177,479,091 - 177,487,306 (-)NCBI
mRatBN7.22175,181,402 - 175,189,619 (-)NCBI
Rnor_6.02189,088,570 - 189,096,785 (-)NCBI
Rnor_5.02208,511,421 - 208,519,636 (-)NCBI
RGSC_v3.42181,961,373 - 181,969,581 (-)RGD
Celera2169,123,949 - 169,132,124 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_062170 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC78724 (Get FASTA)   NCBI Sequence Viewer  
  AAS90354 (Get FASTA)   NCBI Sequence Viewer  
  EDM00614 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000028200
  ENSRNOP00000028200.2
  ENSRNOP00055029894
  ENSRNOP00060038185
  ENSRNOP00065038972
GenBank Protein P12390 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_062170   ⟸   NM_019297
- Peptide Label: precursor
- UniProtKB: Q53YK1 (UniProtKB/Swiss-Prot),   P12390 (UniProtKB/Swiss-Prot),   A6J6H5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000028200   ⟸   ENSRNOT00000028200
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P12390-F1-model_v2 AlphaFold P12390 1-500 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2350 AgrOrtholog
BioCyc Gene G2FUF-52399 BioCyc
Ensembl Genes ENSRNOG00000020778 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOG00055021542 UniProtKB/Swiss-Prot
  ENSRNOG00060026560 UniProtKB/Swiss-Prot
  ENSRNOG00065027552 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000028200 ENTREZGENE
  ENSRNOT00000028200.4 UniProtKB/Swiss-Prot
  ENSRNOT00055036806 UniProtKB/Swiss-Prot
  ENSRNOT00060045994 UniProtKB/Swiss-Prot
  ENSRNOT00065047496 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.58.390 UniProtKB/Swiss-Prot
  2.70.170.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neurotransmitter-gated ion-channel transmembrane domain UniProtKB/TrEMBL
InterPro Neur_chan_lig-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neur_chan_lig-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neur_channel UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neuro-gated_channel_TM_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neuro_actylchol_rec UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neurotrans-gated_channel_TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neurotransmitter_ion_chnl_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nicotinic_acetylcholine_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:54239 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 54239 ENTREZGENE
PANTHER NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT BETA-2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NEUROTRANSMITTER GATED ION CHANNEL UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
Pfam Neur_chan_LBD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neur_chan_memb UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB CHRNB2 RGD
PhenoGen Chrnb2 PhenoGen
PRINTS NICOTINICR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NRIONCHANNEL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE NEUROTR_ION_CHANNEL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000020778 RatGTEx
  ENSRNOG00055021542 RatGTEx
  ENSRNOG00060026560 RatGTEx
  ENSRNOG00065027552 RatGTEx
Superfamily-SCOP Neurotransmitter-gated ion-channel transmembrane pore UniProtKB/TrEMBL
  Nicotinic receptor ligand binding domain-like UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
  SSF90112 UniProtKB/Swiss-Prot
UniProt A6J6H5 ENTREZGENE, UniProtKB/TrEMBL
  ACHB2_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q53YK1 ENTREZGENE
UniProt Secondary Q53YK1 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-11 Chrnb2  cholinergic receptor nicotinic beta 2 subunit  Chrnb2  cholinergic receptor, nicotinic beta 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-11-25 Chrnb2  cholinergic receptor, nicotinic beta 2  Chrnb2  cholinergic receptor, nicotinic, beta 2 (neuronal)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-29 Chrnb2  cholinergic receptor, nicotinic, beta 2 (neuronal)  Chrnb2  cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Chrnb2  cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)    cholinergic receptor, nicotinic, beta polypeptide 2  Name updated 1299863 APPROVED
2002-06-10 Chrnb2  cholinergic receptor, nicotinic, beta polypeptide 2      Symbol and Name status set to approved 70586 APPROVED