Chrnb2 (cholinergic receptor nicotinic beta 2 subunit) - Rat Genome Database

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Gene: Chrnb2 (cholinergic receptor nicotinic beta 2 subunit) Rattus norvegicus
Analyze
Symbol: Chrnb2
Name: cholinergic receptor nicotinic beta 2 subunit
RGD ID: 2350
Description: Enables acetylcholine binding activity; acetylcholine-gated monoatomic cation-selective channel activity; and quaternary ammonium group binding activity. Contributes to heterocyclic compound binding activity. Involved in response to ethanol; response to nicotine; and synaptic signaling. Located in plasma membrane raft. Part of acetylcholine-gated channel complex. Is active in cholinergic synapse; postsynaptic specialization membrane; and presynaptic membrane. Human ortholog(s) of this gene implicated in autosomal dominant nocturnal frontal lobe epilepsy and autosomal dominant nocturnal frontal lobe epilepsy 3. Orthologous to human CHRNB2 (cholinergic receptor nicotinic beta 2 subunit); PARTICIPATES IN acetylcholine signaling pathway via nicotinic acetylcholine receptor; alfentanil pharmacodynamics pathway; bupivacaine pharmacodynamics pathway; INTERACTS WITH (E)-thiamethoxam; (S)-anabasine; (S)-nicotine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: cholinergic receptor nicotinic beta polypeptide 2; cholinergic receptor nicotinic beta subunit 2; cholinergic receptor, nicotinic beta 2; cholinergic receptor, nicotinic, beta 2 (neuronal); cholinergic receptor, nicotinic, beta polypeptide 2; cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal); cholinergic receptor, nicotinic, beta subunit 2; N-alpha 1; neuronal acetylcholine receptor non-alpha-1 chain; neuronal acetylcholine receptor subunit beta-2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82177,479,091 - 177,487,306 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2177,479,091 - 177,491,326 (-)EnsemblGRCr8
mRatBN7.22175,181,402 - 175,189,619 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2175,181,402 - 175,189,619 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx2182,330,071 - 182,338,257 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02180,352,453 - 180,360,643 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02174,953,345 - 174,961,538 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.02189,088,570 - 189,096,785 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2189,088,570 - 189,096,785 (-)Ensemblrn6Rnor6.0
Rnor_5.02208,511,421 - 208,519,636 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42181,961,373 - 181,969,581 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2169,123,949 - 169,132,124 (-)NCBICelera
RGSC_v3.12181,911,478 - 181,919,687 (-)NCBI
Cytogenetic Map2q34NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-lobeline  (ISO)
(E)-thiamethoxam  (EXP)
(S)-anabasine  (EXP)
(S)-nicotine  (EXP,ISO)
1,1-dimethyl-4-phenylpiperazinium iodide  (EXP,ISO)
13-desmethylspirolide C  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
2,2',4,4'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3,5-dibromo-2-(2,4-dibromophenoxy)phenol  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4-nonylphenol  (ISO)
4-octylphenol  (ISO)
acetamiprid  (EXP,ISO)
acetylcholine  (EXP,ISO)
alcuronium  (ISO)
all-trans-retinoic acid  (ISO)
aluminium hydroxide  (ISO)
Amaranth  (EXP)
amitriptyline  (EXP,ISO)
ammonium chloride  (EXP)
Antimony trioxide  (ISO)
antimycin A  (ISO)
atracurium  (ISO)
atropine  (EXP,ISO)
barium(0)  (EXP)
bentonite  (ISO)
benzo[a]pyrene  (EXP,ISO)
bisphenol A  (EXP,ISO)
bleomycin A2  (EXP)
Brilliant Blue  (EXP)
butan-1-ol  (ISO)
calcium atom  (EXP,ISO)
calcium(0)  (EXP,ISO)
carbachol  (EXP,ISO)
carbamazepine  (ISO)
carbaryl  (EXP)
celastrol  (ISO)
chlorpyrifos  (EXP)
choline  (ISO)
cisatracurium  (ISO)
Citreoviridin  (ISO)
clofibrate  (ISO)
clothianidin  (EXP,ISO)
cocaine  (EXP,ISO)
cyclosporin A  (ISO)
cytisine  (EXP,ISO)
decabromodiphenyl ether  (ISO)
decamethonium  (ISO)
deguelin  (ISO)
Desformylflustrabromine  (ISO)
diazinon  (EXP)
dichloroacetic acid  (ISO)
dichlorvos  (ISO)
diethylstilbestrol  (ISO)
dihydro-beta-erythroidine  (EXP,ISO)
dinotefuran  (EXP)
dopamine  (ISO)
endosulfan  (EXP)
epibatidine  (EXP,ISO)
EPTC  (EXP)
erythrosin B  (EXP)
ethanol  (EXP,ISO)
fenoxycarb  (EXP)
flupyradifurone  (EXP)
folic acid  (ISO)
furan  (EXP)
galanthamine  (ISO)
galanthamine Trifluoroacetic acid  (ISO)
genistein  (EXP)
gentamycin  (EXP)
graphite  (EXP)
hexachlorophene  (EXP,ISO)
Hexamethonium  (ISO)
imidacloprid  (EXP,ISO)
indigo carmine  (EXP)
lead diacetate  (EXP)
LY294002  (ISO)
magnesium dihydroxide  (ISO)
Mecamylamine  (EXP,ISO)
mercury dichloride  (EXP)
methyllycaconitine  (EXP,ISO)
Mivacurium  (ISO)
nicotine  (EXP,ISO)
nitenpyram  (EXP)
ochratoxin A  (EXP)
okadaic acid  (ISO)
pancuronium  (ISO)
paracetamol  (ISO)
paraoxon  (EXP)
paraquat  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
PhIP  (EXP)
physostigmine  (ISO)
progesterone  (ISO)
pyrazines  (ISO)
pyridines  (ISO)
rivastigmine  (ISO)
rocuronium  (ISO)
scopolamine  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (ISO)
sterigmatocystin  (EXP)
succinylcholine  (ISO)
sulfoxaflor  (EXP)
Sunset Yellow FCF  (EXP)
T-2 toxin  (ISO)
tacrine  (ISO)
tamoxifen  (ISO)
tartrazine  (EXP)
tetrachloroethene  (EXP,ISO)
tetrachloromethane  (EXP)
thiacloprid  (EXP)
thiamethoxam  (EXP)
toluene  (EXP,ISO)
trichloroethene  (EXP)
triphenyl phosphate  (ISO)
Triptolide  (ISO)
triptonide  (ISO)
tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate  (EXP,ISO)
tubocurarine  (EXP,ISO)
urethane  (EXP)
valproic acid  (EXP,ISO)
varenicline  (EXP,ISO)
vecuronium bromide  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
acetylcholine receptor signaling pathway  (IBA,IEA,IGI,ISO,ISS)
action potential  (ISO)
associative learning  (ISO)
B cell activation  (ISO)
behavioral response to nicotine  (ISO)
calcium ion transport  (ISO)
central nervous system neuron axonogenesis  (ISO)
central nervous system projection neuron axonogenesis  (ISO)
chemical synaptic transmission  (IBA)
cognition  (ISO)
conditioned taste aversion  (ISO)
excitatory postsynaptic potential  (IEA)
lateral geniculate nucleus development  (ISO)
learning  (ISO)
locomotory behavior  (ISO)
membrane depolarization  (IBA,IDA,ISO,ISS)
memory  (ISO)
monoatomic ion transmembrane transport  (IBA,IEA)
monoatomic ion transport  (IEA)
negative regulation of action potential  (ISO)
nervous system process  (ISO)
optic nerve morphogenesis  (ISO)
positive regulation of B cell proliferation  (ISO)
positive regulation of dopamine secretion  (ISO)
positive regulation of synaptic transmission, dopaminergic  (ISO)
presynaptic modulation of chemical synaptic transmission  (ISO)
regulation of circadian sleep/wake cycle, non-REM sleep  (ISO)
regulation of circadian sleep/wake cycle, REM sleep  (ISO)
regulation of dendrite morphogenesis  (ISO)
regulation of dopamine metabolic process  (ISO)
regulation of dopamine secretion  (ISO)
regulation of membrane potential  (ISO)
regulation of postsynaptic membrane potential  (IEA)
regulation of synapse assembly  (ISO)
regulation of synaptic transmission, dopaminergic  (ISO)
response to acetylcholine  (IDA,IGI)
response to cocaine  (ISO)
response to ethanol  (IEA,IEP,ISO)
response to hypoxia  (ISO)
response to nicotine  (IEA,IMP,ISO)
sensory perception of pain  (ISO)
sensory perception of sound  (ISO)
signal transduction  (ISO)
smooth muscle contraction  (ISO)
social behavior  (ISO)
synaptic transmission involved in micturition  (ISO)
synaptic transmission, cholinergic  (IMP,ISO,ISS)
vestibulocochlear nerve development  (ISO)
visual learning  (ISO)
visual perception  (ISO)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
acetylcholine signaling pathway via nicotinic acetylcholine receptor  (ISO)
alfentanil pharmacodynamics pathway  (ISO)
bupivacaine pharmacodynamics pathway  (ISO)
buprenorphine pharmacodynamics pathway  (ISO)
chloroprocaine pharmacodynamics pathway  (ISO)
citalopram pharmacodynamics pathway  (ISO)
cocaine pharmacodynamics pathway  (ISO)
codeine and morphine pharmacodynamics pathway  (ISO)
desipramine pharmacodynamics pathway  (ISO)
diphenoxylate pharmacodynamics pathway  (ISO)
escitalopram pharmacodynamics pathway  (ISO)
ethylmorphine pharmacodynamics pathway  (ISO)
fentanyl pharmacodynamics pathway  (ISO)
fluoxetine pharmacodynamics pathway  (ISO)
heroin pharmacodynamics pathway  (ISO)
hydrocodone pharmacodynamics pathway  (ISO)
hydromorphone pharmacodynamics pathway  (ISO)
imipramine pharmacodynamics pathway  (ISO)
levacetylmethadol pharmacodynamics pathway  (ISO)
levobupivacaine phgarmacodynamics pathway  (ISO)
levorphanol pharmacodynamics pathway  (ISO)
lidocaine pharmacodynamics pathway  (ISO)
mepivacaine pharmacodynamics pathway  (ISO)
methadone pharmacodynamics pathway  (ISO)
nalbuphine pharmacodynamics pathway  (ISO)
naloxone pharmacodynamics pathway  (ISO)
naltrexone pharmacodynamics pathway  (ISO)
nicotine pharmacodynamics pathway  (ISO)
nicotine pharmacokinetics pathway  (ISO)
oxybuprocaine pharmacodynamics pathway  (ISO)
oxycodone pharmacodynamics pathway  (ISO)
oxymorphone pharmacodynamics pathway  (ISO)
pentazocine pharmacodynamics pathway  (ISO)
prilocaine pharmacodynamics pathway  (ISO)
procaine pharmacodynamics pathway  (ISO)
remifentanil pharmacodynamics pathway  (ISO)
ropivacaine pharmacodynamics pathway  (ISO)
tramadol pharmacodynamics pathway  (ISO)

References

References - curated
# Reference Title Reference Citation
1. E-cigarette aerosols containing nicotine modulate nicotinic acetylcholine receptors and astroglial glutamate transporters in mesocorticolimbic brain regions of chronically exposed mice. Alasmari F, etal., Chem Biol Interact. 2021 Jan 5;333:109308. doi: 10.1016/j.cbi.2020.109308. Epub 2020 Nov 23.
2. Mammalian nicotinic acetylcholine receptors: from structure to function. Albuquerque EX, etal., Physiol Rev. 2009 Jan;89(1):73-120. doi: 10.1152/physrev.00015.2008.
3. Varenicline is a potent partial agonist at alpha6beta2* nicotinic acetylcholine receptors in rat and monkey striatum. Bordia T, etal., J Pharmacol Exp Ther. 2012 Aug;342(2):327-34. doi: 10.1124/jpet.112.194852. Epub 2012 May 1.
4. Functional expression of two neuronal nicotinic acetylcholine receptors from cDNA clones identifies a gene family. Boulter J, etal., Proc Natl Acad Sci U S A 1987 Nov;84(21):7763-7.
5. The a7 nicotinic acetylcholine receptor function in hippocampal neurons is regulated by the lipid composition of the plasma membrane. Colón-Sáez JO and Yakel JL, J Physiol. 2011 Jul 1;589(Pt 13):3163-74. doi: 10.1113/jphysiol.2011.209494. Epub 2011 May 3.
6. HMGB1 neuroimmune signaling and REST-G9a gene repression contribute to ethanol-induced reversible suppression of the cholinergic neuron phenotype. Crews FT, etal., Mol Psychiatry. 2023 Dec;28(12):5159-5172. doi: 10.1038/s41380-023-02160-6. Epub 2023 Jul 4.
7. Primary structure and expression of beta 2: a novel subunit of neuronal nicotinic acetylcholine receptors. Deneris ES, etal., Neuron 1988 Mar;1(1):45-54.
8. Molecular biology and electrophysiology of neuronal nicotinic receptors of rat chromaffin cells. Di Angelantonio S, etal., Eur J Neurosci 2003 Jun;17(11):2313-22.
9. Formation of oligomers containing the beta3 and beta4 subunits of the rat nicotinic receptor. Forsayeth JR and Kobrin E, J Neurosci. 1997 Mar 1;17(5):1531-8.
10. Nicotinic receptor subunit alpha5 modifies assembly, up-regulation, and response to pro-inflammatory cytokines. Gahring LC and Rogers SW, J Biol Chem. 2010 Aug 20;285(34):26049-57. doi: 10.1074/jbc.M110.105346. Epub 2010 Jun 21.
11. Subsynaptic localization of nicotinic acetylcholine receptor subunits: a comparative study in the mouse and rat striatum. Garção P, etal., Neurosci Lett. 2014 Apr 30;566:106-10. doi: 10.1016/j.neulet.2014.02.018. Epub 2014 Mar 4.
12. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
13. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
14. Rat nicotinic ACh receptor alpha7 and beta2 subunits co-assemble to form functional heteromeric nicotinic receptor channels. Khiroug SS, etal., J Physiol 2002 Apr 15;540(Pt 2):425-34.
15. A novel nicotinic acetylcholine receptor subtype in basal forebrain cholinergic neurons with high sensitivity to amyloid peptides. Liu Q, etal., J Neurosci. 2009 Jan 28;29(4):918-29. doi: 10.1523/JNEUROSCI.3952-08.2009.
16. Quantitative analysis of the heteromeric neuronal nicotinic receptors in the rat hippocampus. Lomazzo E, etal., J Neurochem. 2010 Nov;115(3):625-34. doi: 10.1111/j.1471-4159.2010.06967.x. Epub 2010 Sep 27.
17. The ultrastructural distribution of putative nicotinic receptors on cultured neurons from the rat superior cervical ganglion. Loring RH, etal., Neuroscience. 1988 Mar;24(3):1071-80.
18. Nicotinic cholinergic receptors in the rat retina: simple and mixed heteromeric subtypes. Marritt AM, etal., Mol Pharmacol. 2005 Dec;68(6):1656-68. Epub 2005 Aug 29.
19. Postsynaptic alpha 4 beta 2 and alpha 7 type nicotinic acetylcholine receptors contribute to the local and endogenous acetylcholine-mediated synaptic transmissions in nigral dopaminergic neurons. Matsubayashi H, etal., Brain Res. 2004 Apr 16;1005(1-2):1-8.
20. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
21. Modulation of neuronal nicotinic acetylcholine receptors by halothane in rat cortical neurons. Mori T, etal., Mol Pharmacol. 2001 Apr;59(4):732-43.
22. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
23. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
24. Online Mendelian Inheritance in Man, OMIM (TM). Online Mendelian Inheritance in Man, OMIM (TM).
25. Nicotinic acetylcholine receptor alpha 7 regulates cAMP signal within lipid rafts. Oshikawa J, etal., Am J Physiol Cell Physiol. 2003 Sep;285(3):C567-74. Epub 2003 May 14.
26. CHRNB2 is the second acetylcholine receptor subunit associated with autosomal dominant nocturnal frontal lobe epilepsy. Phillips HA, etal., Am J Hum Genet 2001 Jan;68(1):225-31. Epub 2000 Dec 5.
27. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
28. UBXD4, a UBX-containing protein, regulates the cell surface number and stability of alpha3-containing nicotinic acetylcholine receptors. Rezvani K, etal., J Neurosci. 2009 May 27;29(21):6883-96. doi: 10.1523/JNEUROSCI.4723-08.2009.
29. GOA pipeline RGD automated data pipeline
30. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
31. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
32. Five ADNFLE mutations reduce the Ca2+ dependence of the mammalian alpha4beta2 acetylcholine response. Rodrigues-Pinguet N, etal., J Physiol 2003 Jul 1;550(Pt 1):11-26. Epub 2003 May 16.
33. An extracellular protein microdomain controls up-regulation of neuronal nicotinic acetylcholine receptors by nicotine. Sallette J, etal., J Biol Chem 2004 Apr 30;279(18):18767-75. Epub 2004 Feb 5.
34. The comparative pharmacology and up-regulation of rat neuronal nicotinic receptor subtype binding sites stably expressed in transfected mammalian cells. Xiao Y and Kellar KJ, J Pharmacol Exp Ther. 2004 Jul;310(1):98-107. Epub 2004 Mar 11.
35. Increased neurodegeneration during ageing in mice lacking high-affinity nicotine receptors. Zoli M, etal., EMBO J 1999 Mar 1;18(5):1235-44.
Additional References at PubMed
PMID:7870173   PMID:8906617   PMID:9428762   PMID:9614223   PMID:10235262   PMID:10531434   PMID:11027228   PMID:11044747   PMID:11145999   PMID:11222635   PMID:11282258   PMID:11344259  
PMID:11955523   PMID:12079404   PMID:12097474   PMID:12189247   PMID:12876201   PMID:12944511   PMID:14687550   PMID:15215293   PMID:15450117   PMID:15456819   PMID:15464132   PMID:15469877  
PMID:15489024   PMID:15541879   PMID:15569257   PMID:15608630   PMID:15741168   PMID:15788760   PMID:15929983   PMID:15955596   PMID:15963492   PMID:15964197   PMID:16014729   PMID:16033901  
PMID:16253349   PMID:16407231   PMID:16772172   PMID:16965547   PMID:17192655   PMID:17301182   PMID:17470777   PMID:17559419   PMID:17626178   PMID:17900292   PMID:18387948   PMID:18583454  
PMID:18602971   PMID:18818999   PMID:19095841   PMID:19187266   PMID:19567877   PMID:20238211   PMID:20616056   PMID:20633015   PMID:22064677   PMID:22253754   PMID:22323734   PMID:23056257  
PMID:23219030   PMID:23429044   PMID:23583932   PMID:23734673   PMID:23811311   PMID:23846688   PMID:24398291   PMID:25713061   PMID:26276394   PMID:26858154   PMID:27721068   PMID:28666811  


Genomics

Comparative Map Data
Chrnb2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82177,479,091 - 177,487,306 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2177,479,091 - 177,491,326 (-)EnsemblGRCr8
mRatBN7.22175,181,402 - 175,189,619 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2175,181,402 - 175,189,619 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx2182,330,071 - 182,338,257 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02180,352,453 - 180,360,643 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02174,953,345 - 174,961,538 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.02189,088,570 - 189,096,785 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2189,088,570 - 189,096,785 (-)Ensemblrn6Rnor6.0
Rnor_5.02208,511,421 - 208,519,636 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42181,961,373 - 181,969,581 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2169,123,949 - 169,132,124 (-)NCBICelera
RGSC_v3.12181,911,478 - 181,919,687 (-)NCBI
Cytogenetic Map2q34NCBI
CHRNB2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381154,567,778 - 154,580,013 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1154,567,778 - 154,580,013 (+)Ensemblhg38GRCh38
GRCh371154,540,254 - 154,552,489 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361152,806,881 - 152,818,978 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341151,353,329 - 151,362,156NCBI
Celera1127,611,891 - 127,623,988 (+)NCBICelera
Cytogenetic Map1q21.3NCBI
HuRef1125,903,718 - 125,915,813 (+)NCBIHuRef
CHM1_11155,936,657 - 155,948,754 (+)NCBICHM1_1
T2T-CHM13v2.01153,704,898 - 153,719,720 (+)NCBIT2T-CHM13v2.0
Chrnb2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39389,660,755 - 89,671,939 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl389,653,502 - 89,671,939 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38389,753,448 - 89,764,632 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl389,746,195 - 89,764,632 (-)Ensemblmm10GRCm38
MGSCv37389,557,370 - 89,568,554 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36389,839,375 - 89,850,512 (-)NCBIMGSCv36mm8
Celera389,790,490 - 89,801,674 (-)NCBICelera
Cytogenetic Map3F1NCBI
cM Map339.19NCBI
Chrnb2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555451,065,457 - 1,077,526 (+)Ensembl
ChiLan1.0NW_0049555451,065,457 - 1,077,056 (+)NCBIChiLan1.0ChiLan1.0
CHRNB2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2195,254,104 - 95,266,251 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1194,986,423 - 94,998,575 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01129,922,740 - 129,931,582 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11133,535,023 - 133,547,361 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1133,535,023 - 133,547,361 (+)EnsemblpanPan2panpan1.1
CHRNB2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1742,786,505 - 42,797,976 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl742,789,600 - 42,795,722 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha742,277,266 - 42,288,752 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0742,656,510 - 42,668,001 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl742,656,517 - 42,667,042 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1742,435,765 - 42,447,248 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0742,489,629 - 42,501,090 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0742,773,221 - 42,784,709 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Chrnb2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505825,136,236 - 25,149,726 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365804,166,619 - 4,186,443 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365804,165,255 - 4,179,285 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CHRNB2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl495,198,717 - 95,211,037 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1495,196,992 - 95,211,084 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24104,024,711 - 104,036,882 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CHRNB2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1209,245,803 - 9,255,430 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl209,247,231 - 9,253,795 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660388,581,863 - 8,595,204 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Chrnb2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248852,843,899 - 2,848,522 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248852,839,607 - 2,851,934 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Chrnb2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1363,894,939 - 63,902,819 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Chrnb2
345 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:91
Count of miRNA genes:68
Interacting mature miRNAs:81
Transcripts:ENSRNOT00000028200
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358356Srcrt1Stress Responsive Cort QTL13.66blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)2163997722225110681Rat
1578648Bss11Bone structure and strength QTL 114.7femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)2169358774214358774Rat
1331734Bp204Blood pressure QTL 2043.61192arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2170656145239614549Rat
631566Bp90Blood pressure QTL 900.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2149957381221199885Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)244537979205135428Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)267845370229470703Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)283465462229820014Rat
10755499Bp389Blood pressure QTL 3892.61arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)220695736231474293Rat
1298076Bp166Blood pressure QTL 1660.0009arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2138595962205135428Rat
1581576Pur7Proteinuria QTL 70.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)280396178220931218Rat
61457Niddm8Non-insulin dependent diabetes mellitus QTL 84.10.01blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)2176840779178247591Rat
152025245Scl81Serum cholesterol level QTL 813.49blood cholesterol amount (VT:0000180)2124537199209621565Rat
1581578Cm49Cardiac mass QTL 494.90.01heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)2145807215220931416Rat
631198Cm22Cardiac mass QTL 224.30.0008heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)278269809208420281Rat
1554319Bmd2Bone mineral density QTL 213.40.0001lumbar vertebra area (VT:0010570)lumbar vertebra cross-sectional area (CMO:0001689)2122597372215234002Rat
12879836Kidm61Kidney mass QTL 610.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2154723085199723085Rat
1581569Uae32Urinary albumin excretion QTL 320.0001urine protein amount (VT:0005160)urine albumin excretion rate (CMO:0000757)280396178220931218Rat
10043136Iddm54Insulin dependent diabetes mellitus QTL 543.40.0001blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)2145807215190807215Rat
12879837Am2Aortic mass QTL 20.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)2154723085199723085Rat
10043139Iddm55Insulin dependent diabetes mellitus QTL 553.10.0001blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)2150313808195313808Rat
12879838Cm86Cardiac mass QTL 860.002heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)2154723085199723085Rat
1302793Bw16Body weight QTL 1650.0001body mass (VT:0001259)body weight (CMO:0000012)2159440891205135267Rat
12879839Cm85Cardiac mass QTL 850.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)2154723085199723085Rat
1549833Bp257Blood pressure QTL 2570.003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2170652929215652929Rat
1358900Bw48Body weight QTL 484.88body mass (VT:0001259)body weight (CMO:0000012)2159440891220931218Rat
4889834Pur24Proteinuria QTL 245.80.014urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)2171994826205135428Rat
12879845Cm89Cardiac mass QTL 890.008heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)2154723085178247591Rat
61473Bp19Blood pressure QTL 196.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2175008837178247591Rat
1359030Bp277Blood pressure QTL 277arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2143565208188565208Rat
12879846Cm90Cardiac mass QTL 900.011heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)2154723085178247591Rat
12879847Am4Aortic mass QTL 40.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)2154723085178247591Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)24265106205135428Rat
12879840Bw179Body weight QTL 1790.005body mass (VT:0001259)body weight (CMO:0000012)2154723085199723085Rat
1581502Esta3Estrogen-induced thymic atrophy QTL 3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)2139067258192287892Rat
1359032Hrtrt18Heart rate QTL 18heart pumping trait (VT:2000009)heart rate (CMO:0000002)2159440760195313808Rat
2301966Bp322Blood pressure QTL 3223.58arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2144882354205135428Rat
1298080Bp163Blood pressure QTL 1630.02arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)267845182205135428Rat
1357991Ael2Aortic elastin QTL 24.20.000071aorta elastin amount (VT:0003905)aortic elastin2169227906214227906Rat
8662832Vetf7Vascular elastic tissue fragility QTL 73.5aorta elastin amount (VT:0003905)aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)283400752223709938Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)244537979205135428Rat
1578671Bmd10Bone mineral density QTL 105.4femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)2175931416220931416Rat
1359022Ppulsi1Prepulse inhibition QTL 13.63prepulse inhibition trait (VT:0003088)acoustic startle response measurement (CMO:0001519)2139067258184067258Rat
1641891Alcrsp17Alcohol response QTL 17response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2151869660251712708Rat
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)280396034220931416Rat
61374Edpm2Estrogen-dependent pituitary mass QTL 24.420.86pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)278269809205135428Rat
8662843Vetf9Vascular elastic tissue fragility QTL 92.05thoracic aorta molecular composition trait (VT:0010568)aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)2159440760228950743Rat
2301415Cm67Cardiac mass QTL 670.003heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)2154723085178247591Rat
1331794Bp202Blood pressure QTL 2023.66819arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2143344967251712708Rat
71113Cari2Carrageenan-induced inflammation QTL 22.70.009hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)2143746578205135428Rat
1331805Cm29Cardiac mass QTL 293.50746heart mass (VT:0007028)heart wet weight (CMO:0000069)2143344967251712708Rat
11565180Kidm56Kidney mass QTL 560.003kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2154723085178247591Rat
634308Sach6Saccharin preference QTL 64.9taste sensitivity trait (VT:0001986)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)2114384617215381366Rat
1598805Memor8Memory QTL 83exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)2150096616195096616Rat
11565181Bw176Body weight QTL 1760.002body mass (VT:0001259)body weight (CMO:0000012)2154723085178247591Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
724568Uae13Urinary albumin excretion QTL 134.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)2145306936212705578Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
1300165Rf9Renal function QTL 93.28kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)2113746222205135428Rat
61401Niddm2Non-insulin dependent diabetes mellitus QTL 24.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2147287892192287892Rat
631507Bp105Blood pressure QTL 1050.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2114384617215381366Rat
1641925Alcrsp2Alcohol response QTL 2response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2151869660223841096Rat
1354609Niddm62Non-insulin dependent diabetes mellitus QTL 624.720.000006insulin secretion trait (VT:0003564)plasma insulin level (CMO:0000342)2117415288205135428Rat
1598833Bp295Blood pressure QTL 2953.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2150096616195096616Rat
1354622Kidm16Kidney mass QTL 163kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)283465462225110681Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)247856345205135428Rat
631522Bp74Blood pressure QTL 740.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2175008837220008837Rat
7488927Bp365Blood pressure QTL 3650.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2165453811210453811Rat
7488925Bp364Blood pressure QTL 3640.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2163253030208253030Rat
2293843Kiddil6Kidney dilation QTL 63.1kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)244537979184731399Rat
2306901Bp337Blood pressure QTL 3370.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2166372086229820014Rat
1354605Rf48Renal function QTL 482.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)276328396209350714Rat
7488904Bp363Blood pressure QTL 3630.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2175279960178247591Rat

Markers in Region
BF388105  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22175,181,080 - 175,181,261 (+)MAPPERmRatBN7.2
Rnor_6.02189,088,249 - 189,088,429NCBIRnor6.0
Rnor_5.02208,511,100 - 208,511,280UniSTSRnor5.0
RGSC_v3.42181,961,052 - 181,961,232UniSTSRGSC3.4
Celera2169,123,628 - 169,123,808UniSTS
RH 3.4 Map21155.4UniSTS
Cytogenetic Map2q34UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
15 6 56 149 68 67 36 60 36 6 258 140 3 134 62 84 31 16 16

Sequence


Ensembl Acc Id: ENSRNOT00000028200   ⟹   ENSRNOP00000028200
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2177,479,091 - 177,487,306 (-)Ensembl
mRatBN7.2 Ensembl2175,181,402 - 175,189,619 (-)Ensembl
Rnor_6.0 Ensembl2189,088,570 - 189,096,785 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000130732   ⟹   ENSRNOP00000107367
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2177,479,091 - 177,491,326 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000135469   ⟹   ENSRNOP00000102532
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2177,479,091 - 177,491,326 (-)Ensembl
RefSeq Acc Id: NM_019297   ⟹   NP_062170
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82177,479,091 - 177,487,306 (-)NCBI
mRatBN7.22175,181,402 - 175,189,619 (-)NCBI
Rnor_6.02189,088,570 - 189,096,785 (-)NCBI
Rnor_5.02208,511,421 - 208,519,636 (-)NCBI
RGSC_v3.42181,961,373 - 181,969,581 (-)RGD
Celera2169,123,949 - 169,132,124 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_062170 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC78724 (Get FASTA)   NCBI Sequence Viewer  
  AAS90354 (Get FASTA)   NCBI Sequence Viewer  
  EDM00614 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000028200
  ENSRNOP00000028200.2
GenBank Protein P12390 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_062170   ⟸   NM_019297
- Peptide Label: precursor
- UniProtKB: Q53YK1 (UniProtKB/Swiss-Prot),   P12390 (UniProtKB/Swiss-Prot),   A6J6H5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000028200   ⟸   ENSRNOT00000028200
Ensembl Acc Id: ENSRNOP00000102532   ⟸   ENSRNOT00000135469
Ensembl Acc Id: ENSRNOP00000107367   ⟸   ENSRNOT00000130732
Protein Domains
Neurotransmitter-gated ion-channel ligand-binding   Neurotransmitter-gated ion-channel transmembrane

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P12390-F1-model_v2 AlphaFold P12390 1-500 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2350 AgrOrtholog
BioCyc Gene G2FUF-52399 BioCyc
Ensembl Genes ENSRNOG00000020778 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000028200 ENTREZGENE
  ENSRNOT00000028200.4 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.58.390 UniProtKB/Swiss-Prot
  2.70.170.10 UniProtKB/Swiss-Prot
InterPro Neur_chan_lig-bd UniProtKB/Swiss-Prot
  Neur_chan_lig-bd_sf UniProtKB/Swiss-Prot
  Neur_channel UniProtKB/Swiss-Prot
  Neuro-gated_channel_TM_sf UniProtKB/Swiss-Prot
  Neuro_actylchol_rec UniProtKB/Swiss-Prot
  Neurotrans-gated_channel_TM UniProtKB/Swiss-Prot
  Neurotransmitter_ion_chnl_CS UniProtKB/Swiss-Prot
  Nicotinic_acetylcholine_rcpt UniProtKB/Swiss-Prot
KEGG Report rno:54239 UniProtKB/Swiss-Prot
NCBI Gene 54239 ENTREZGENE
PANTHER PTHR18945 UniProtKB/Swiss-Prot
Pfam Neur_chan_LBD UniProtKB/Swiss-Prot
  Neur_chan_memb UniProtKB/Swiss-Prot
PharmGKB CHRNB2 RGD
PhenoGen Chrnb2 PhenoGen
PRINTS NICOTINICR UniProtKB/Swiss-Prot
  NRIONCHANNEL UniProtKB/Swiss-Prot
PROSITE NEUROTR_ION_CHANNEL UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000020778 RatGTEx
Superfamily-SCOP SSF63712 UniProtKB/Swiss-Prot
  SSF90112 UniProtKB/Swiss-Prot
UniProt A0ABK0L1V8_RAT UniProtKB/TrEMBL
  A0ABK0LY12_RAT UniProtKB/TrEMBL
  A6J6H5 ENTREZGENE, UniProtKB/TrEMBL
  ACHB2_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q53YK1 ENTREZGENE
UniProt Secondary Q53YK1 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-11 Chrnb2  cholinergic receptor nicotinic beta 2 subunit  Chrnb2  cholinergic receptor, nicotinic beta 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-11-25 Chrnb2  cholinergic receptor, nicotinic beta 2  Chrnb2  cholinergic receptor, nicotinic, beta 2 (neuronal)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-29 Chrnb2  cholinergic receptor, nicotinic, beta 2 (neuronal)  Chrnb2  cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Chrnb2  cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)    cholinergic receptor, nicotinic, beta polypeptide 2  Name updated 1299863 APPROVED
2002-06-10 Chrnb2  cholinergic receptor, nicotinic, beta polypeptide 2      Symbol and Name status set to approved 70586 APPROVED