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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2350
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Chrnb2
Name: cholinergic receptor nicotinic beta 2 subunit
Acc ID: CHEBI:34905
Term: paraquat
Definition: An organic cation that consists of 4,4'-bipyridine bearing two N-methyl substituents loctated at the 1- and 1'-positions.
Chemical ID: MESH:D010269
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Chrnb2multiple interactionsISOChrnb2 (Mus musculus)6480464CTDNicotine inhibits the reaction [Paraquat results in decreased expression of [CHRNA6 protein binds to CHRNB2 protein]]; Paraquat results in decreased expression of [CHRNA6 protein binds to CHRNB2 protein]PMID:17227438
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