GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Chrnb2 | multiple interactions | EXP | | 2303194 | RGD | cytisine affects binding to Chrnb2 protein; cytisine competes with [Epibatidine binds to Chrnb2 protein] | | Chrnb2 | multiple interactions | EXP | | 2303195 | RGD | cytisine affects binding to Chrnb2 protein; cytisine inhibits the reaction [epibatidine affects binding to Chrnb2 protein] in rat retina | | Chrnb2 | affects binding | ISO | CHRNB2 (Homo sapiens) | 6480464 | CTD | cytisine binds to [CHRNA4 protein binds to CHRNB2 protein] | PMID:9336329 | Chrnb2 | affects expression | ISO | Chrnb2 (Mus musculus) | 6480464 | CTD | cytisine affects the expression of CHRNB2 protein | PMID:7756618 | Chrnb2 | multiple interactions | ISO | CHRNB2 (Homo sapiens) | 6480464 | CTD | cytisine binds to and results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]; cytisine inhibits the reaction [epibatidine binds to [CHRNA4 protein binds to CHRNB2 protein]]; cytisine results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]; Nicotine inhibits the reaction [cytisine binds to [CHRNA4 protein binds to CHRNB2 protein]]; pozanicline inhibits the reaction [cytisine binds to [CHRNA4 protein binds to CHRNB2 protein]] | PMID:14645658 PMID:20331614 PMID:9336329 | Chrnb2 | multiple interactions | ISO | Chrnb2 (Mus musculus) | 6480464 | CTD | cytisine inhibits the reaction [Nicotine results in increased expression of CHRNB2 protein] | PMID:7756618 | |
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