| 70946 | Pip | prolactin induced protein | ENCODES a protein that exhibits aspartic-type endopeptidase activity (ortholog); identical protein binding (ortholog); IgG binding (ortholog); INVOLVED IN detection of chemical stimulus involved in sensory perception of bitter taste (ortholog); negative regulation of T cell apoptotic process (orthol og); positive regulation of gene expression (ortholog); ASSOCIATED WITH sinusitis (ortholog); FOUND IN apical plasma membrane (ortholog); extracellular region (ortholog); extracellular space (ortholog); INTERACTS WITH 3H-1,2-dithiole-3-thione; 6-propyl-2-thiouracil; ammonium chloride | 4 | 71754265 | 71758559 | Rat | 60 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 621833 | Bpnt1 | 3'(2'), 5'-bisphosphate nucleotidase 1 | ENCODES a protein that exhibits 3'(2'),5'-bisphosphate nucleotidase activity; inositol-1,4-bisphosphate 1-phosphatase activity; magnesium ion binding; INVOLVED IN phosphatidylinositol phosphate biosynthetic process (inferred); PARTICIPATES IN sulfite oxidase deficiency pathway; sulfur metabolic path way; ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); FOUND IN mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 13 | 99397127 | 99425056 | Rat | 96 | old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 62062 | Mybbp1a | MYB binding protein 1a | ENCODES a protein that exhibits sequence-specific DNA binding; E-box binding (ortholog); transcription corepressor activity (ortholog); INVOLVED IN cellular response to glucose starvation (ortholog); circadian regulation of gene expression (ortholog); intrinsic apoptotic signaling pathway by p53 cla ss mediator (ortholog); ASSOCIATED WITH autistic disorder (ortholog); Meniere's disease (ortholog); Prostatic Neoplasms (ortholog); FOUND IN B-WICH complex (ortholog); cytoplasm (ortholog); NLS-dependent protein nuclear import complex (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,4-dinitrotoluene | 10 | 57555458 | 57565819 | Rat | 194 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1311347 | Pipox | pipecolic acid and sarcosine oxidase | ENCODES a protein that exhibits L-pipecolate oxidase activity (ortholog); sarcosine oxidase activity (ortholog); INVOLVED IN L-lysine catabolic process to acetyl-CoA via L-pipecolate (ortholog); PARTICIPATES IN 2-aminoadipic 2-oxoadipic aciduria pathway; glutaric aciduria type I pathway; hyperlysinemia pathway; ASSOCIATED WITH peroxisomal disease (ortholog); FOUND IN peroxisome (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 10 | 63267946 | 63281556 | Rat | 143 | symbol , old_gene_name , PhenoGen , name , description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307475 | Pip4p1 | phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1 | ENCODES a protein that exhibits phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity (ortholog); INVOLVED IN cholesterol metabolic process (ortholog); lysosome localization (ortholog); phosphatidylinositol dephosphorylation (ortholog); FOUND IN late endosome membrane (ortholog); lysosomal me mbrane (ortholog); phagocytic vesicle membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; azoxystrobin; bisphenol A | 15 | 26620399 | 26624369 | Rat | 113 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306225 | Pip4p2 | phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2 | ENCODES a protein that exhibits phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity (ortholog); INVOLVED IN negative regulation of phagocytosis (ortholog); phosphatidylinositol dephosphorylation (ortholog); FOUND IN late endosome membrane (ortholog); lysosomal membrane (ortholog); phagocyti c vesicle membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 5 | 33057046 | 33104448 | Rat | 118 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 621708 | Pip4k2a | phosphatidylinositol-5-phosphate 4-kinase type 2 alpha | ENCODES a protein that exhibits 1-phosphatidylinositol-4-phosphate 5-kinase activity (ortholog); 1-phosphatidylinositol-5-phosphate 4-kinase activity (ortholog); protein homodimerization activity (ortholog); INVOLVED IN 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process (ortholog); autophagosome-lysosome fusion (ortholog); megakaryocyte development (ortholog); PARTICIPATES IN phosphoinositide metabolic pathway; inositol phosphate metabolic pathway; phosphatidylinositol 3-kinase signaling pathway; ASSOCIATED WITH melanoma (ortholog); FOUND IN autophagosome (ortholog); cytosol (ortholog); lysosome (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 6-propyl-2-thiouracil | 17 | 86405080 | 86576597 | Rat | 166 | symbol , old_gene_name , PhenoGen , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 621710 | Pip4k2b | phosphatidylinositol-5-phosphate 4-kinase type 2 beta | ENCODES a protein that exhibits 1-phosphatidylinositol-4-phosphate 5-kinase activity (ortholog); ATP binding (ortholog); GTP binding (ortholog); INVOLVED IN 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process (ortholog); autophagosome-lysosome fusion (ortholog); negative regulation of insulin receptor signaling pathway (ortholog); PARTICIPATES IN inositol phosphate metabolic pathway; phosphatidylinositol 3-kinase signaling pathway; ASSOCIATED WITH hereditary neutrophilia (ortholog); FOUND IN autophagosome (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine | 10 | 83202379 | 83231292 | Rat | 141 | symbol , old_gene_name , PhenoGen , old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 621711 | Pip4k2c | phosphatidylinositol-5-phosphate 4-kinase type 2 gamma | ENCODES a protein that exhibits 1-phosphatidylinositol-4-phosphate 5-kinase activity; identical protein binding (ortholog); INVOLVED IN 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process (ortholog); negative regulation of insulin receptor signaling pathway (ortholog); positive regu lation of autophagosome assembly (ortholog); PARTICIPATES IN inositol phosphate metabolic pathway; phosphatidylinositol 3-kinase signaling pathway; FOUND IN autophagosome (ortholog); cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; acrylamide | 7 | 64905322 | 64920380 | Rat | 112 | symbol , old_gene_name , PhenoGen , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1306127 | Pip5k1a | phosphatidylinositol-4-phosphate 5-kinase, type 1, alpha | ENCODES a protein that exhibits 1-phosphatidylinositol-4-phosphate 5-kinase activity (ortholog); kinase binding (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); activation of GTPase activity (ortholog); cell chemotaxis (ortholog); PARTICIPATES IN Arf family mediated signaling path way; E-cadherin signaling pathway; phosphoinositide metabolic pathway; ASSOCIATED WITH autosomal dominant intellectual developmental disorder 60 with seizures (ortholog); Experimental Neoplasms (ortholog); Lymphatic Metastasis (ortholog); FOUND IN cytosol (ortholog); lamellipodium (ortholog); mRNA cleavage and polyadenylation specificity factor complex (ortholog); INTERACTS WITH 4,4'-sulfonyldiphenol; acrylamide; allethrin | 2 | 185317319 | 185361859 | Rat | 167 | symbol , old_gene_name , PhenoGen , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1310914 | Pip5k1b | phosphatidylinositol-4-phosphate 5-kinase type 1 beta | ENCODES a protein that exhibits 1-phosphatidylinositol-4-phosphate 5-kinase activity (ortholog); INVOLVED IN phosphatidylinositol biosynthetic process (ortholog); phosphatidylinositol metabolic process (ortholog); PARTICIPATES IN Wnt signaling, canonical pathway; endocytosis pathway; Fc gamma recept or mediated signaling pathway; FOUND IN cytosol (ortholog); uropod (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; all-trans-retinoic acid | 1 | 231331836 | 231610092 | Rat | 134 | symbol , old_gene_name , PhenoGen , old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309938 | Pip5k1c | phosphatidylinositol-4-phosphate 5-kinase type 1 gamma | ENCODES a protein that exhibits 1-phosphatidylinositol-4-phosphate 5-kinase activity (ortholog); talin binding (ortholog); INVOLVED IN axonogenesis (ortholog); phosphatidylinositol biosynthetic process (ortholog); phosphatidylinositol metabolic process (ortholog); PARTICIPATES IN clathrin-dependent synaptic vesicle endocytosis; E-cadherin signaling pathway; epidermal growth factor/neuregulin signaling pathway; ASSOCIATED WITH genetic disease (ortholog); lethal congenital contracture syndrome 3 (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN presynaptic endocytic zone membrane; cytosol (ortholog); endosome membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; Brodifacoum | 7 | 9048135 | 9076751 | Rat | 134 | symbol , old_gene_name , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1597527 | Pip5kl1 | phosphatidylinositol-4-phosphate 5-kinase-like 1 | ENCODES a protein that exhibits 1-phosphatidylinositol-4-phosphate 5-kinase activity (ortholog); INVOLVED IN negative regulation of cell migration (ortholog); negative regulation of mitochondrial membrane potential (ortholog); negative regulation of phosphatidylinositol 3-kinase/protein kinase B sig nal transduction (ortholog); FOUND IN cell projection (ortholog); cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; gentamycin | 3 | 36258141 | 36266902 | Rat | 46 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 620849 | Dut | deoxyuridine triphosphatase | ENCODES a protein that exhibits dUTP diphosphatase activity; identical protein binding; peroxisome proliferator activated receptor binding; INVOLVED IN dUMP biosynthetic process; dUTP catabolic process; liver development; PARTICIPATES IN pyrimidine metabolic pathway; beta-ureidopropionase deficiency pathway; dihydropyrimidinase deficiency pathway; ASSOCIATED WITH Bone Marrow Failure and Diabetes Mellitus Syndrome (ortholog); Brain Neoplasms (ortholog); High Myopia (ortholog); FOUND IN mitochondrion (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 3 | 132952258 | 132963433 | Rat | 225 | old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 621343 | Gprasp1 | G protein-coupled receptor associated sorting protein 1 | INVOLVED IN endosome to lysosome transport (ortholog); G protein-coupled receptor catabolic process (ortholog); FOUND IN cytosol (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene | X | 103556493 | 103564275 | Rat | 89 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 620541 | Inpp5j | inositol polyphosphate-5-phosphatase J | ENCODES a protein that exhibits inositol-polyphosphate 5-phosphatase activity; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity (ortholog); INVOLVED IN negative regulation of microtubule polymerization; negative regulation of neuron projection development; negative regulation of pepti dyl-serine phosphorylation (ortholog); PARTICIPATES IN inositol metabolic pathway; inositol phosphate metabolic pathway; phosphatidylinositol 3-kinase signaling pathway; FOUND IN growth cone; ruffle; ruffle membrane; INTERACTS WITH 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine | 14 | 82597789 | 82608930 | Rat | 101 | old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308600 | Dipk1b | divergent protein kinase domain 1B | FOUND IN endoplasmic reticulum membrane (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole | 3 | 29852710 | 29862248 | Rat | 75 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1309953 | Tgs1 | trimethylguanosine synthase 1 | ENCODES a protein that exhibits RNA cap trimethylguanosine synthase activity (ortholog); INVOLVED IN cellular response to fatty acid; cellular response to glucose stimulus; negative regulation of protein import into nucleus; PARTICIPATES IN RNA transport pathway; ASSOCIATED WITH basal cell carcinoma (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; bisphenol A | 5 | 21322492 | 21356017 | Rat | 72 | old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307902 | Mtmr12 | myotubularin related protein 12 | FOUND IN cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; bisphenol A | 2 | 62950722 | 63020319 | Rat | 56 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1592067 | Pikfyve | phosphoinositide kinase, FYVE-type zinc finger containing | ENCODES a protein that exhibits 1-phosphatidylinositol-3-phosphate 5-kinase activity (ortholog); 1-phosphatidylinositol-4-phosphate 5-kinase activity (ortholog); 1-phosphatidylinositol-5-kinase activity (ortholog); INVOLVED IN 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process (orthol og); antigen processing and presentation of exogenous peptide antigen via MHC class II (ortholog); intracellular signal transduction (ortholog); PARTICIPATES IN inositol metabolic pathway; phosphoinositide metabolic pathway; inositol phosphate metabolic pathway; ASSOCIATED WITH Crohn's disease (ortholog); Fleck corneal dystrophy (ortholog); genetic disease (ortholog); FOUND IN cell-cell junction (ortholog); cytoplasmic vesicle (ortholog); cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amphetamine | 9 | 74057488 | 74151610 | Rat | 170 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 628780 | Csdc2 | cold shock domain containing C2 | ENCODES a protein that exhibits RNA binding; transcription factor binding; INVOLVED IN mRNA processing (inferred); FOUND IN cytoplasm (inferred); nucleus (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; alpha-Zearalanol | 7 | 115332134 | 115346599 | Rat | 75 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1310791 | Gtsf1 | gametocyte specific factor 1 | ENCODES a protein that exhibits tRNA binding (ortholog); INVOLVED IN piRNA-mediated gene silencing by mRNA destabilization (ortholog); secondary piRNA processing (ortholog); FOUND IN cytoplasm (ortholog); piP-body (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; amitrole; methimazole | 7 | 136417793 | 136436849 | Rat | 36 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1306942 | Tdrd9 | tudor domain containing 9 | ENCODES a protein that exhibits ATP hydrolysis activity (ortholog); INVOLVED IN fertilization (ortholog); male meiosis I (ortholog); male meiotic nuclear division (ortholog); ASSOCIATED WITH azoospermia (ortholog); COVID-19 (ortholog); male infertility (ortholog); FOUND IN cytoplasm (ortholog); nucl eus (ortholog); piP-body (ortholog); INTERACTS WITH bisphenol A; N,N-diethyl-m-toluamide; permethrin | 6 | 136850797 | 136966225 | Rat | 102 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1307379 | Asap1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | ENCODES a protein that exhibits GTPase activator activity (ortholog); phosphatidylinositol-3,4,5-trisphosphate binding (ortholog); phosphatidylinositol-4,5-bisphosphate binding (ortholog); INVOLVED IN cilium assembly (ortholog); negative regulation of dendritic spine development (ortholog); positive regulation of membrane tubulation (ortholog); PARTICIPATES IN Arf family mediated signaling pathway; endocytosis pathway; Fc gamma receptor mediated signaling pathway; ASSOCIATED WITH juvenile rheumatoid arthritis (ortholog); pulmonary tuberculosis (ortholog); urinary bladder cancer (ortholog); FOUND IN cell projection membrane (ortholog); cytosol (ortholog); dendritic spine (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; all-trans-retinoic acid | 7 | 97675354 | 97982523 | Rat | 176 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1308614 | Aldh7a1 | aldehyde dehydrogenase 7 family, member A1 | ENCODES a protein that exhibits aldehyde dehydrogenase (NAD+) activity (ortholog); betaine-aldehyde dehydrogenase (NAD+) activity (ortholog); identical protein binding (ortholog); INVOLVED IN endosome to lysosome transport (ortholog); energy homeostasis (ortholog); Golgi to endosome transport (ortho log); PARTICIPATES IN 2-aminoadipic 2-oxoadipic aciduria pathway; choline metabolic pathway; glutaric aciduria type I pathway; ASSOCIATED WITH benign neonatal seizures (ortholog); bone disease (ortholog); coloboma (ortholog); FOUND IN cytosol (ortholog); Golgi membrane (ortholog); mitochondrion (ortholog); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine | 18 | 52208035 | 52240293 | Rat | 287 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 2012 | Acadm | acyl-CoA dehydrogenase medium chain | ENCODES a protein that exhibits acyl-CoA dehydrogenase activity; flavin adenine dinucleotide binding; identical protein binding; INVOLVED IN fatty acid beta-oxidation using acyl-CoA dehydrogenase; medium-chain fatty acid catabolic process; response to copper ion; PARTICIPATES IN fatty acid beta degr adation pathway; 3-hydroxy-3-methylglutaryl-CoA lyase deficiency pathway; 3-hydroxyisobutyric aciduria pathway; ASSOCIATED WITH metabolic dysfunction-associated steatotic liver disease; Congenital Hydrocephalus 2, with or without Brain or Eye Anomalies (ortholog); genetic disease (ortholog); FOUND IN mitochondrial matrix; mitochondrial membrane; axon (ortholog); INTERACTS WITH (+)-schisandrin B; 1-[(2,3,4-trimethoxyphenyl)methyl]piperazine; 1-naphthyl isothiocyanate | 2 | 245518693 | 245542864 | Rat | 435 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1359366 | Acat2 | acetyl-CoA acetyltransferase 2 | ENCODES a protein that exhibits acetyl-CoA C-acetyltransferase activity; INVOLVED IN cellular response to fatty acid; cellular response to nutrient; ketone body catabolic process; PARTICIPATES IN alendronate pharmacodynamics pathway; cholesterol biosynthetic pathway; cholesterol ester storage diseas e pathway; ASSOCIATED WITH arteriosclerosis (ortholog); coronary artery disease (ortholog); Cytosolic Acetoacetyl-CoA Thiolase Deficiency (ortholog); FOUND IN cytoplasm (ortholog); INTERACTS WITH 1-(3-(trifluoromethyl)phenyl)piperazine; 1-benzylpiperazine; 1-naphthyl isothiocyanate | 1 | 50100840 | 50118886 | Rat | 323 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 2165 | Atf3 | activating transcription factor 3 | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA binding (ortholog); INVOLVED IN positive regulation of cell population proliferation; positive regulation of transcript ion by RNA polymerase II; cellular response to amino acid starvation (ortholog); PARTICIPATES IN transforming growth factor-beta Smad dependent signaling pathway; ASSOCIATED WITH Myocardial Reperfusion Injury; Cardiomegaly (ortholog); cardiomyopathy (ortholog); FOUND IN CHOP-ATF3 complex (ortholog); nucleolus (ortholog); nucleoplasm (ortholog); INTERACTS WITH (S)-amphetamine; 1,2,4-trimethylbenzene; 1-[(2,3,4-trimethoxyphenyl)methyl]piperazine | 13 | 105274103 | 105331653 | Rat | 802 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 2174 | Atp2a2 | ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 | ENCODES a protein that exhibits ATP binding; calcium ion binding; lutropin-choriogonadotropic hormone receptor binding; INVOLVED IN calcium ion import into sarcoplasmic reticulum; calcium ion transmembrane transport; calcium ion transport; PARTICIPATES IN acebutolol pharmacodynamics pathway; adrener gic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; ASSOCIATED WITH abdominal obesity-metabolic syndrome 1; Acute Experimental Pancreatitis; Cachexia; FOUND IN apical ectoplasmic specialization; extrinsic component of cytoplasmic side of plasma membrane; perinuclear region of cytoplasm; INTERACTS WITH (+)-pilocarpine; (R)-noradrenaline; 1-[(2,3,4-trimethoxyphenyl)methyl]piperazine | 12 | 39733519 | 39782942 | Rat | 539 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 621496 | Bhmt | betaine-homocysteine S-methyltransferase | ENCODES a protein that exhibits betaine-homocysteine S-methyltransferase activity; identical protein binding; methyltransferase activity; INVOLVED IN methionine biosynthetic process; protein methylation; response to alcohol; PARTICIPATES IN methionine cycle/metabolic pathway; remethylation pathway o f homocysteine metabolism - cobalamin independent, betaine dependent; choline metabolic pathway; ASSOCIATED WITH alcohol-associated liver disease; metabolic dysfunction and alcohol associated liver disease; cerebral infarction (ortholog); FOUND IN cytosol; extracellular space; nucleus; INTERACTS WITH 1-(3-(trifluoromethyl)phenyl)piperazine; 1-benzylpiperazine; 17beta-estradiol | 2 | 26594852 | 26614429 | Rat | 269 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 620943 | Crym | crystallin, mu | ENCODES a protein that exhibits delta1-piperideine-2-carboxylate reductase activity (ortholog); hormone binding (ortholog); NADP binding (ortholog); INVOLVED IN mitochondrial transport; response to hormone; response to vitamin D; ASSOCIATED WITH autosomal domina nt nonsyndromic deafness 40 (ortholog); congestive heart failure (ortholog); Deafness (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); mitochondrion (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 17beta-estradiol | 1 | 183991752 | 184006923 | Rat | 172 | old_gene_name , description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 2462 | Cyp24a1 | cytochrome P450, family 24, subfamily a, polypeptide 1 | ENCODES a protein that exhibits 1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity; 25-hydroxycholecalciferol-24-hydroxylase activity; vitamin D 24-hydroxylase activity; INVOLVED IN cellular response to vitamin D; vitamin D catabolic process; vitamin D metabolic process; ASSOCIATED WITH nephroto xicity; autism spectrum disorder (ortholog); breast carcinoma (ortholog); FOUND IN mitochondrion (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-butan-2-yl-4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-1,2,4-triazol-3-one; 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine | 3 | 179694647 | 179709083 | Rat | 333 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 2481 | Cyp51 | cytochrome P450, family 51 | ENCODES a protein that exhibits sterol 14-demethylase activity; heme binding (ortholog); INVOLVED IN cholesterol biosynthetic process via 24,25-dihydrolanosterol; positive regulation of oocyte development; response to human chorionic gonadotropin; PARTICIPATES IN cholesterol biosynthetic pathway; al endronate pharmacodynamics pathway; cholesterol ester storage disease pathway; ASSOCIATED WITH diabetes mellitus; Hypercholesterolemia; Antley-Bixler syndrome (ortholog); FOUND IN acrosomal vesicle; INTERACTS WITH 1-(3-(trifluoromethyl)phenyl)piperazine; 1-benzylpiperazine; 1-naphthyl isothiocyanate | 4 | 30991693 | 31010147 | Rat | 407 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 71016 | Cyp8b1 | cytochrome P450 family 8 subfamily B member 1 | ENCODES a protein that exhibits sterol 12-alpha-hydroxylase activity; INVOLVED IN response to cholesterol; response to nutrient levels; bile acid biosynthetic process (ortholog); PARTICIPATES IN bile acid biosynthetic pathway; cerebrotendinous xanthomatosis pathway; congenital bile acid synthesis de fect pathway; ASSOCIATED WITH extrahepatic cholestasis; Chemical and Drug Induced Liver Injury (ortholog); cholestasis (ortholog); FOUND IN endoplasmic reticulum membrane (inferred); INTERACTS WITH (+)-schisandrin B; 1,3,7,9-tetramethyluric acid; 1-(3-(trifluoromethyl)phenyl)piperazine | 8 | 130455622 | 130457592 | Rat | 290 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 68423 | Dlg3 | discs large MAGUK scaffold protein 3 | ENCODES a protein that exhibits ionotropic glutamate receptor binding; PDZ domain binding; protein domain specific binding; INVOLVED IN establishment of planar polarity (ortholog); establishment or maintenance of epithelial cell apical/basal polarity (ortholog); regulation of postsynaptic membrane n eurotransmitter receptor levels (ortholog); ASSOCIATED WITH epilepsy (ortholog); genetic disease (ortholog); intellectual disability (ortholog); FOUND IN dendritic shaft; glutamatergic synapse; growth cone; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 4-[1-hydroxy-2-[4-(phenylmethyl)-1-piperidinyl]propyl]phenol | X | 69899694 | 69951928 | Rat | 180 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 71087 | Epb41l1 | erythrocyte membrane protein band 4.1-like 1 | ENCODES a protein that exhibits signaling receptor binding; INVOLVED IN regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane (ortholog); ASSOCIATED WITH autosomal dominant intellectual developmental disorder 11 (ortholog); developmental and epileptic encephalopathy 11 (ortholog); intellectual disability (ortholog); FOUND IN parallel fiber to Purkinje cell synapse; postsynapse; presynapse; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; 4-[1-hydroxy-2-[4-(phenylmethyl)-1-piperidinyl]propyl]phenol | 3 | 165389295 | 165512821 | Rat | 151 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 621678 | Fads1 | fatty acid desaturase 1 | ENCODES a protein that exhibits acyl-CoA (8-3)-desaturase activity; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water; acyl-CoA 6-desaturase activity (ortholog); INVOLVED IN arachidonate metab olic process; response to fenofibrate; response to hormone; PARTICIPATES IN alpha-linolenic acid metabolic pathway; linoleic acid metabolic pathway; unsaturated fatty acid biosynthetic pathway; ASSOCIATED WITH Cardiac Fibrosis; congestive heart failure; Experimental Diabetes Mellitus; FOUND IN endoplasmic reticulum membrane (ortholog); mitochondrion (ortholog); INTERACTS WITH (+)-schisandrin B; (+)-sesamin; 1-(3-(trifluoromethyl)phenyl)piperazine | 1 | 216252605 | 216267618 | Rat | 292 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 61834 | Fdft1 | farnesyl diphosphate farnesyl transferase 1 | ENCODES a protein that exhibits squalene synthase [NAD(P)H] activity (ortholog); INVOLVED IN cholesterol biosynthetic process; farnesyl diphosphate metabolic process; cholesterol biosynthetic process via desmosterol (ortholog); PARTICIPATES IN cholesterol biosynthetic pathway; alendronate pharmacody namics pathway; cholesterol ester storage disease pathway; ASSOCIATED WITH alcohol use disorder; cataract; cannabis abuse (ortholog); FOUND IN endoplasmic reticulum membrane; cytoplasmic side of endoplasmic reticulum membrane (ortholog); endoplasmic reticulum (ortholog); INTERACTS WITH 1,2,4-trimethylbenzene; 1-(3-(trifluoromethyl)phenyl)piperazine; 1-benzylpiperazine | 15 | 41588114 | 41616168 | Rat | 375 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 68953 | Fdps | farnesyl diphosphate synthase | ENCODES a protein that exhibits (2E,6E)-farnesyl diphosphate synthase activity; dimethylallyltranstransferase activity (ortholog); INVOLVED IN cellular response to fatty acid; farnesyl diphosphate biosynthetic process; male gonad development; PARTICIPATES IN alendronate pharmacodynamics pathway; cho lesterol biosynthetic pathway; cholesterol ester storage disease pathway; ASSOCIATED WITH alcohol use disorder; Porokeratosis 9, Multiple Types (ortholog); Postmenopausal Osteoporosis (ortholog); FOUND IN mitochondrial matrix; peroxisome; cytosol (ortholog); INTERACTS WITH 1-(3-(trifluoromethyl)phenyl)piperazine; 1-benzylpiperazine; 1-naphthyl isothiocyanate | 2 | 176795192 | 176804816 | Rat | 390 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 2683 | Ggt1 | gamma-glutamyltransferase 1 | ENCODES a protein that exhibits aminoacyltransferase activity; glutathione hydrolase activity (ortholog); leukotriene-C(4) hydrolase activity (ortholog); INVOLVED IN cellular response to oxidative stress; hepatoblast differentiation; hepatocyte differentiation; PARTICIPATES IN acetylsalicylic acid p harmacodynamics pathway; antipyrine drug pathway; arachidonic acid metabolic pathway; ASSOCIATED WITH aflatoxins-related hepatocellular carcinoma; alcohol dependence; Chemical and Drug Induced Liver Injury; FOUND IN extracellular space; plasma membrane (ortholog); vesicle (ortholog); INTERACTS WITH (R)-lipoic acid; (S)-nicotine; 1-[(2,3,4-trimethoxyphenyl)methyl]piperazine | 20 | 13074141 | 13103551 | Rat | 428 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 71008 | Gpnmb | glycoprotein nmb | ENCODES a protein that exhibits heparin binding (ortholog); integrin binding (ortholog); receptor ligand activity (ortholog); INVOLVED IN bone mineralization; osteoblast differentiation; cell adhesion (ortholog); ASSOCIATED WITH brain infarction; acute kidney failure (ortholog); Acute Liver Failure (ortholog); FOUND IN cytoplasmic vesicle (ortholog); membrane (ortholog); plasma membrane (ortholog); INTERACTS WITH 1,2-dimethylhydrazine; 1-(3-(trifluoromethyl)phenyl)piperazine; 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine | 4 | 79341128 | 79362366 | Rat | 293 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 61983 | Grn | granulin precursor | ENCODES a protein that exhibits protein-folding chaperone binding (ortholog); INVOLVED IN chondrocyte proliferation; male mating behavior; neural precursor cell proliferation; ASSOCIATED WITH status epilepticus; Alzheimer's disease (ortholog); amyotrophic lateral sclerosis (ortholog); FOUND IN gluta matergic synapse; synapse; cerebellar climbing fiber to Purkinje cell synapse (ortholog); INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 1-[(2,3,4-trimethoxyphenyl)methyl]piperazine; 1-naphthyl isothiocyanate | 10 | 87887834 | 87893938 | Rat | 370 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 2845 | Htr1a | 5-hydroxytryptamine receptor 1A | ENCODES a protein that exhibits G protein-coupled serotonin receptor activity; G-protein alpha-subunit binding; serotonin binding; INVOLVED IN adenylate cyclase-inhibiting serotonin receptor signaling pathway; behavioral response to nicotine; negative regulation of gamma-aminobutyric acid secretion; PARTICIPATES IN alfentanil pharmacodynamics pathway; bupivacaine pharmacodynamics pathway; buprenorphine pharmacodynamics pathway; ASSOCIATED WITH alcohol use disorder; anxiety disorder; Catalepsy; FOUND IN axon hillock; GABA-ergic synapse; neuronal cell body; INTERACTS WITH (+)-pilocarpine; (S)-nicotine; 1-(3-chlorophenyl)piperazine | 2 | 38427169 | 38431733 | Rat | 331 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 621835 | Idi1 | isopentenyl-diphosphate delta isomerase 1 | ENCODES a protein that exhibits isopentenyl-diphosphate delta-isomerase activity (ortholog); magnesium ion binding (ortholog); manganese ion binding (ortholog); INVOLVED IN cholesterol biosynthetic process via desmosterol (ortholog); cholesterol biosynthetic process via lathosterol (ortholog); farne syl diphosphate biosynthetic process, mevalonate pathway (ortholog); PARTICIPATES IN alendronate pharmacodynamics pathway; cholesterol biosynthetic pathway; cholesterol ester storage disease pathway; FOUND IN peroxisome; cytosol (ortholog); INTERACTS WITH 1-(3-(trifluoromethyl)phenyl)piperazine; 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine; 1-benzylpiperazine | 17 | 66539761 | 66547524 | Rat | 381 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1583578 | Il20 | interleukin 20 | ENCODES a protein that exhibits cytokine activity (ortholog); interleukin-20 receptor binding (ortholog); interleukin-22 receptor binding (ortholog); INVOLVED IN positive regulation of osteoclast differentiation (ortholog); PARTICIPATES IN Jak-Stat signaling pathway; ASSOCIATED WITH end stage renal disease; Experimental Arthritis; acute kidney failure (ortholog); FOUND IN extracellular space (ortholog); interleukin-20 receptor complex (ortholog); INTERACTS WITH 1,2-dimethylhydrazine; 1-[(2,3,4-trimethoxyphenyl)methyl]piperazine; mercury dichloride | 13 | 44933249 | 44936893 | Rat | 68 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 620281 | Msmo1 | methylsterol monooxygenase 1 | ENCODES a protein that exhibits C-4 methylsterol oxidase activity (ortholog); INVOLVED IN cholesterol biosynthetic process via desmosterol (ortholog); zymosterol biosynthetic process (ortholog); PARTICIPATES IN alendronate pharmacodynamics pathway; cholesterol biosynthetic pathway; cholesterol ester storage disease pathway; ASSOCIATED WITH genetic disease (ortholog); Microcephaly, Congenital Cataract, and Psoriasiform Dermatitis (ortholog); FOUND IN endoplasmic reticulum membrane (inferred); INTERACTS WITH 1-(3-(trifluoromethyl)phenyl)piperazine; 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine; 1-benzylpiperazine | 16 | 29747113 | 29764360 | Rat | 360 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 621458 | Nefl | neurofilament light chain | ENCODES a protein that exhibits phospholipase binding; protein domain specific binding; protein-containing complex binding; INVOLVED IN cerebral cortex development; hippocampus development; intermediate filament polymerization or depolymerization; PARTICIPATES IN amyotrophic lateral sclerosis pathwa y; ASSOCIATED WITH congenital hypothyroidism; depressive disorder; Experimental Autoimmune Encephalomyelitis; FOUND IN axon; growth cone; neurofilament; INTERACTS WITH (-)-anisomycin; 1-[(2,3,4-trimethoxyphenyl)methyl]piperazine; 2,3,7,8-tetrachlorodibenzodioxine | 15 | 46477330 | 46481203 | Rat | 422 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 3187 | Notch1 | notch receptor 1 | ENCODES a protein that exhibits transmembrane signaling receptor activity; chromatin binding (ortholog); chromatin DNA binding (ortholog); INVOLVED IN animal organ regeneration; astrocyte differentiation; cell differentiation in spinal cord; PARTICIPATES IN Notch signaling pathway; Notch signaling p athway; altered Notch signaling pathway; ASSOCIATED WITH Carotid Artery Injuries; Diabetic Cardiomyopathies; Experimental Autoimmune Uveitis; FOUND IN acrosomal vesicle; nucleus; plasma membrane; INTERACTS WITH 1,2-dimethylhydrazine; 1-[(2,3,4-trimethoxyphenyl)methyl]piperazine; 17alpha-ethynylestradiol | 3 | 29676040 | 29721613 | Rat | 916 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 728909 | Pcsk9 | proprotein convertase subtilisin/kexin type 9 | ENCODES a protein that exhibits apolipoprotein binding (ortholog); apolipoprotein receptor binding (ortholog); endopeptidase activity (ortholog); INVOLVED IN cellular response to insulin stimulus; cellular response to starvation; cholesterol homeostasis; ASSOCIATED WITH autosomal recessive hyperchol esterolemia (ortholog); coronary artery disease (ortholog); Coronary Disease (ortholog); FOUND IN extracellular space; cell surface (ortholog); COPII-coated ER to Golgi transport vesicle (ortholog); INTERACTS WITH 1,2-dimethylhydrazine; 1-(3-(trifluoromethyl)phenyl)piperazine; 1-benzylpiperazine | 5 | 126440102 | 126462507 | Rat | 388 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 3344 | Plcb1 | phospholipase C beta 1 | ENCODES a protein that exhibits calcium ion binding; identical protein binding; phosphatidylinositol-4,5-bisphosphate phospholipase C activity; INVOLVED IN cellular response to fluoride; cellular response to glyceraldehyde; cellular response to ionomycin; PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; ASSOCIATED WITH abnormal depression-related behavior; ASSOCIATED WITH myocardial infarction; acute myeloid leukemia (ortholog); Alzheimer's disease (ortholog); FOUND IN chromatin (ortholog); cytoplasm (ortholog); GABA-ergic synapse (ortholog); INTERACTS WITH (+)-schisandrin B; (R)-noradrenaline; 1-(3-chlorophenyl)piperazine | 3 | 142512765 | 143224042 | Rat | 474 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1310007 | Rragd | Ras-related GTP binding D | ENCODES a protein that exhibits GDP binding (ortholog); GTP binding (ortholog); GTPase activity (ortholog); INVOLVED IN cellular response to L-leucine (ortholog); cellular response to leucine starvation (ortholog); positive regulation of TORC1 signaling (ortholog); PARTICIPATES IN mTOR signaling pat hway; ASSOCIATED WITH genetic disease (ortholog); renal hypomagnesemia 7, with or without dilated cardiomyopathy (ortholog); FOUND IN cytoplasm (ortholog); Gtr1-Gtr2 GTPase complex (ortholog); lysosome (ortholog); INTERACTS WITH 1-(3-(trifluoromethyl)phenyl)piperazine; 1-benzylpiperazine; 17beta-estradiol | 5 | 52170234 | 52205700 | Rat | 179 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 620314 | Ryr2 | ryanodine receptor 2 | ENCODES a protein that exhibits calcium-induced calcium release activity; ryanodine-sensitive calcium-release channel activity; scaffold protein binding; INVOLVED IN calcium ion transmembrane transport; manganese ion transmembrane transport; monoatomic ion transmembrane transport; PARTICIPATES IN ac ebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; ASSOCIATED WITH congestive heart failure; Experimental Diabetes Mellitus; pulmonary hypertension; FOUND IN A band; extrinsic component of cytoplasmic side of plasma membrane; nuclear envelope; INTERACTS WITH (S)-nicotine; 1-[(2,3,4-trimethoxyphenyl)methyl]piperazine; 17beta-estradiol | 17 | 63081527 | 63667141 | Rat | 474 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 62072 | Slc18a3 | solute carrier family 18 member A3 | ENCODES a protein that exhibits acetylcholine transmembrane transporter activity; acetylcholine:proton antiporter activity; monoamine:proton antiporter activity (ortholog); INVOLVED IN acetylcholine transport; acetylcholine uptake; neurotransmitter loading into synaptic vesicle; PARTICIPATES IN acet ylcholine signaling pathway via muscarinic acetylcholine receptor; acetylcholine signaling pathway via nicotinic acetylcholine receptor; ASSOCIATED WITH asthma; Binge Drinking; bladder disease; FOUND IN AP-1 adaptor complex; AP-2 adaptor complex; axon; INTERACTS WITH (S)-nicotine; 1-[(2,3,4-trimethoxyphenyl)methyl]piperazine; 4-amino-2,6-dinitrotoluene | 16 | 7719953 | 7722814 | Rat | 121 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 3704 | Slc2a1 | solute carrier family 2 member 1 | ENCODES a protein that exhibits D-glucose transmembrane transporter activity; dehydroascorbic acid transmembrane transporter activity; kinase binding; INVOLVED IN cellular hyperosmotic response; cellular response to mechanical stimulus; cerebral cortex development; PARTICIPATES IN facilitative sugar transporter mediated glucose transport pathway; Glut1 deficiency syndrome pathway; hypoxia inducible factor pathway; ASSOCIATED WITH alcohol dependence; Alcohol-Related Disorders; Diabetic Nephropathies; FOUND IN apical plasma membrane; basolateral plasma membrane; caveola; INTERACTS WITH (-)-epigallocatechin 3-gallate; 1-[(2,3,4-trimethoxyphenyl)methyl]piperazine; 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile | 5 | 138002522 | 138030742 | Rat | 875 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 3717 | Slc8a1 | solute carrier family 8 member A1 | ENCODES a protein that exhibits calcium:sodium antiporter activity; ankyrin binding (ortholog); calcium ion binding (ortholog); INVOLVED IN calcium ion export; calcium ion import; calcium ion transmembrane transport; PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agoni st and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; ASSOCIATED WITH brain ischemia; Cardiomegaly; congestive heart failure; FOUND IN axon; cell projection; dendrite; INTERACTS WITH (R)-noradrenaline; 1-[(2,3,4-trimethoxyphenyl)methyl]piperazine; 17alpha-ethynylestradiol | 6 | 18975498 | 19299704 | Rat | 441 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 621768 | Slpi | secretory leukocyte peptidase inhibitor | ENCODES a protein that exhibits DNA binding (ortholog); endopeptidase inhibitor activity (ortholog); enzyme binding (ortholog); INVOLVED IN antibacterial humoral response (ortholog); immune response (ortholog); innate immune response (ortholog); ASSOCIATED WITH Acute Lung Injury; chronic obstructive pulmonary disease; endophthalmitis; FOUND IN extracellular space (ortholog); INTERACTS WITH 1-[(2,3,4-trimethoxyphenyl)methyl]piperazine; 17alpha-ethynylestradiol; 17beta-estradiol | 3 | 173501573 | 173503822 | Rat | 266 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 3755 | Sqle | squalene epoxidase | ENCODES a protein that exhibits squalene monooxygenase activity; FAD binding (ortholog); INVOLVED IN cholesterol metabolic process; response to biphenyl; cholesterol biosynthetic process (ortholog); PARTICIPATES IN alendronate pharmacodynamics pathway; cholesterol biosynthetic pathway; cholesterol e ster storage disease pathway; ASSOCIATED WITH cholelithiasis (ortholog); Experimental Liver Neoplasms (ortholog); Hypercholesterolemia (ortholog); FOUND IN cytoplasmic side of endoplasmic reticulum membrane (ortholog); endoplasmic reticulum membrane (ortholog); membrane (ortholog); INTERACTS WITH 1-(3-(trifluoromethyl)phenyl)piperazine; 1-benzylpiperazine; 1-naphthyl isothiocyanate | 7 | 92758175 | 92773049 | Rat | 416 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 3727 | Sult2a6 | sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 6 | ENCODES a protein that exhibits alcohol sulfotransferase activity (inferred); bile-salt sulfotransferase activity (inferred); sulfotransferase activity (inferred); INVOLVED IN lipid metabolic process (inferred); steroid metabolic process (inferred); FOUND IN cytoplasm (inferred); cytosol (inferred); INTERACTS WITH (+)-schisandrin B; 1-(3-(trifluoromethyl)phenyl)piperazine; 1-benzylpiperazine | 1 | 84046685 | 84097808 | Rat | 67 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 621090 | Syngap1 | synaptic Ras GTPase activating protein 1 | ENCODES a protein that exhibits GTPase activator activity; protein kinase binding; INVOLVED IN negative regulation of Ras protein signal transduction; regulation of synaptic plasticity; dendrite development (ortholog); PARTICIPATES IN calcium/calmodulin dependent kinase 2 signaling pathway; ASSOCIAT ED WITH autistic disorder (ortholog); autosomal dominant intellectual developmental disorder 5 (ortholog); autosomal recessive intellectual developmental disorder 5 (ortholog); FOUND IN glutamatergic synapse; postsynaptic density, intracellular component; synapse; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4-[1-hydroxy-2-[4-(phenylmethyl)-1-piperidinyl]propyl]phenol; acetamide | 20 | 5028226 | 5058519 | Rat | 137 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 619799 | Vegfb | vascular endothelial growth factor B | ENCODES a protein that exhibits chemoattractant activity (ortholog); identical protein binding (ortholog); vascular endothelial growth factor receptor 1 binding (ortholog); INVOLVED IN angiogenesis; response to xenobiotic stimulus; cardiac muscle contraction (ortholog); PARTICIPATES IN vascular endo thelial growth factor signaling pathway; ceramide signaling pathway; mTOR signaling pathway; ASSOCIATED WITH Brain Injuries; retinal vein occlusion; Breast Neoplasms (ortholog); FOUND IN extracellular region (ortholog); extracellular space (ortholog); growth factor complex (ortholog); INTERACTS WITH 1-[(2,3,4-trimethoxyphenyl)methyl]piperazine; 1-naphthyl isothiocyanate; 17beta-estradiol | 1 | 213601570 | 213607254 | Rat | 222 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1561043 | Tut1 | terminal uridylyl transferase 1, U6 snRNA-specific | ENCODES a protein that exhibits enzyme binding (ortholog); enzyme-substrate adaptor activity (ortholog); mRNA 3'-UTR binding (ortholog); INVOLVED IN co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway (ortholog); histone mRNA catabolic process (ortholog); mRNA 3'-end proc essing (ortholog); FOUND IN mRNA cleavage and polyadenylation specificity factor complex (ortholog); nuclear speck (ortholog); nucleolus (ortholog); INTERACTS WITH (+)-schisandrin B; 6-propyl-2-thiouracil; bisphenol A | 1 | 215277802 | 215288869 | Rat | 110 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |